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Incidental Mutations

86 incidental mutations are currently displayed, and affect 86 genes.

18 are Possibly Damaging.

18 are Probably Damaging.

35 are Probably Benign.

12 are Probably Null.

8 create premature stop codons.

0 are critical splice junction mutations.

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Mutations in Coding Regions/Splice Sites Identified by Next-Gen Sequencing

[records 1 to 86 of 86] 10 25 50 100 500 1000 per page Full List
	ID	Source UTSW APN	Gene	E-score	Stock #	Gen G0 G0' G1 G2 G3 G3R F1 F2 F3 C0 C1 C2 C3 D1 HES IPS A3	Quality -	Vld Y N ?	Strain	Chr 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 X Y	Position	Mutation A R N D C E Q G H I L K M F P S T W Y V * A R N D C E Q G H I L K M F P S T W Y V *	Ref A C G T -	Var A C G T -	Type makesense missense nonsense start codon destroyed start gained synonymous splice acceptor site splice donor site critical splice acceptor site critical splice donor site splice site large deletion large insertion rearrangement small deletion small insertion exon frame shift intragenic intron utr 3 prime utr 5 prime unclassified	Exon Dist	Zygosity Homo Het Hemi Null	Predicted Effect unknown probably benign probably null possibly damaging probably damaging noncoding transcript silent not run no transcript	PPH Score -	Meta Score	MGI Phenotype available none listed	Posted
1	350543		1700031F05Rik		R4648	G1	222	N		X	102860909	N132K	G	T	missense		Het	possibly damaging	0.816			10/08/2015
2	350497		2010315B03Rik	0.124	R4648	G1	168	N		9	124293598	Y232F	T	A	missense		Het	probably benign	0.004			10/08/2015
3	350530		2310079G19Rik	0.168	R4648	G1	225	N		16	88627367	S79G	T	C	missense		Het	probably benign	0.371			10/08/2015
4	350460		4930568D16Rik	0.214	R4648	G1	225	N		2	35354446	Y298F	T	A	missense		Het	probably damaging	1.000			10/08/2015
5	350537		Alpk2	0.209	R4648	G1	225	N		18	65349882	F352L	A	G	missense		Het	probably damaging	0.987			10/08/2015
6	350525		Angpt1	1.000	R4648	G1	225	N		15	42676184	Y93F	T	A	missense		Het	probably benign	0.016		phenotype	10/08/2015
7	350522		Ankrd33b	0.095	R4648	G1	225	N		15	31325024	*129W	T	C	makesense		Het	probably null				10/08/2015
8	350529		Atp5j	0.380	R4648	G1	225	N		16	84828455	M87V	T	C	missense		Het	probably benign	0.014		phenotype	10/08/2015
9	350501		Atp8b3	0.175	R4648	G1	225	N		10	80525623	S822P	A	G	missense		Het	possibly damaging	0.945		phenotype	10/08/2015
10	350505		Bbs10	0.189	R4648	G1	225	N		10	111301134	K703E	A	G	missense		Het	probably benign	0.016	0.014	phenotype	10/08/2015
11	350488		Bbs2	0.329	R4648	G1	225	N		8	94080879	V429E	A	T	missense		Het	probably damaging	1.000		phenotype	10/08/2015
12	500713		Bccip	0.960	R4648	G1	225	N		7	133714899	L83F	C	T	missense		Het	probably damaging	1.000		phenotype	12/01/2017
13	350518		Brd9	0.859	R4648	G1	225	N		13	73940776	V198I	G	A	missense		Het	probably benign	0.372			10/08/2015
14	350542		C1galt1c1	0.144	R4648	G1	222	N		X	38631472	S216T	A	T	missense		Het	probably benign	0.057		phenotype	10/08/2015
15	350472		C77080	0.227	R4648	G1	225	N		4	129221940	T977K	G	T	missense		Het	probably benign	0.002			10/08/2015
16	350541		Calhm1	0.403	R4648	G1	225	N		19	47143801	L125P	A	G	missense		Het	probably damaging	0.983		phenotype	10/08/2015
17	350487		Ccdc110	0.081	R4648	G1	225	N		8	45942668	Q532L	A	T	missense		Het	possibly damaging	0.953			10/08/2015
18	350454		Cdh19	0.033	R4648	G1	225	N		1	110925177	L343F	G	A	missense		Het	probably benign	0.040		phenotype	10/08/2015
19	350455		Cep350	0.884	R4648	G1	225	N		1	155902598	S1653P	A	G	missense		Het	possibly damaging	0.845		phenotype	10/08/2015
20	350490		Cmtm4	0.069	R4648	G1	225	N		8	104356320	I135T	A	G	missense		Het	possibly damaging	0.854		phenotype	10/08/2015
21	350519		Cmya5	0.221	R4648	G1	225	N		13	93093828	L1584P	A	G	missense		Het	possibly damaging	0.838			10/08/2015
22	350453		Crocc2	0.181	R4648	G1	225	N		1	93168794	V24M	G	A	missense		Het	possibly damaging	0.948	0.278		10/08/2015
23	350457		Crp	0.000	R4648	G1	225	N		1	172698137	M1V	A	G	start codon destroyed		Het	probably null	0.236		phenotype	10/08/2015
24	350486		Csmd1	0.290	R4648	G1	225	N		8	15998788	Q2305*	G	A	nonsense		Het	probably null			phenotype	10/08/2015
25	350540		Cyp2c38	0.147	R4648	G1	225	N		19	39460688	I74F	T	A	missense		Het	probably benign	0.047			10/08/2015
26	500712		Dab1	0.705	R4648	G1	225	N		4	104731751	A524V	C	T	missense		Het	probably benign	0.289	0.212	phenotype	12/01/2017
27	350495		Dcaf1	1.000	R4648	G1	225	N		9	106865677		A	T	unclassified		Het	probably benign			phenotype	10/08/2015
28	350532		Dhx16	0.922	R4648	G1	225	N		17	35885635	A565G	C	G	missense		Het	probably benign	0.105		phenotype	10/08/2015
29	350469		Dock7	0.000	R4648	G1	225	N		4	98969644	E1448*	C	A	nonsense		Het	probably null			phenotype	10/08/2015
30	350538		Dpf2	0.797	R4648	G1	225	N		19	5907081	R38H	C	T	missense		Het	probably damaging	1.000		phenotype	10/08/2015
31	350498		E030030I06Rik	0.867	R4648	G1	178	N		10	22148845	R56S	T	A	missense		Het	unknown				10/08/2015
32	350483		Etnk1	0.952	R4648	G1	225	N		6	143195274	Y248C	A	G	missense		Het	probably damaging	1.000		phenotype	10/08/2015
33	350526		Ext1	1.000	R4648	G1	225	N		15	53089987	S494P	A	G	missense		Het	possibly damaging	0.947		phenotype	10/08/2015
34	350478		Gk2	0.000	R4648	G1	225	N		5	97455720	S420G	T	C	missense		Het	probably benign	0.043			10/08/2015
35	350506		Gm26596		R4648	G1	225	N		10	112929159		T	C	unclassified		Het	probably benign				10/08/2015
36	350527		Gm5414	0.185	R4648	G1	225	N		15	101628108	N27K	G	T	missense		Het	possibly damaging	0.724			10/08/2015
37	350514		Gskip	0.104	R4648	G1	225	N		12	105698729	D9G	A	G	missense		Het	probably benign	0.174		phenotype	10/08/2015
38	500714		H2-K2	0.501	R4648	G1	225	N		17	33976015		T	A	splice site		Het	noncoding transcript				12/01/2017
39	350500		Hk1	0.244	R4648	G1	225	N		10	62304779	S105R	T	G	missense		Het	probably benign	0.001		phenotype	10/08/2015
40	350502		Hmg20b	0.408	R4648	G1	225	N		10	81348582	Q129L	T	A	missense		Het	probably damaging	0.991			10/08/2015
41	350517		Idnk	0.000	R4648	G1	225	N		13	58162869	D67G	A	G	missense		Het	probably benign	0.053		phenotype	10/08/2015
42	350451		Igfbp5	0.096	R4648	G1	225	N		1	72864063	H118N	G	T	missense		Het	probably benign	0.015		phenotype	10/08/2015
43	350515		Irf4	0.317	R4648	G1	225	N		13	30763597	Y427F	A	T	missense		Het	probably benign	0.003		phenotype	10/08/2015
44	350494		Khdc3	0.213	R4648	G1	225	N		9	73102586	E26G	A	G	missense		Het	possibly damaging	0.806		phenotype	10/08/2015
45	350485		Kif7	1.000	R4648	G1	225	N		7	79709191	D512G	T	C	missense		Het	probably damaging	0.998		phenotype	10/08/2015
46	350458		Lamb3	0.394	R4648	G1	225	N		1	193331357	I513N	T	A	missense		Het	probably damaging	0.986		phenotype	10/08/2015
47	350539		Lipo1	0.070	R4648	G1	225	N		19	33783460	L174P	A	G	missense		Het	probably damaging	0.995			10/08/2015
48	350475		Lnx1	0.158	R4648	G1	225	N		5	74610796	V350I	C	T	missense		Het	probably benign	0.158		phenotype	10/08/2015
49	350491		Map3k21	0.434	R4648	G1	225	N		8	125942111	D812G	A	G	missense		Het	probably benign	0.000			10/08/2015
50	350470		Mast2	0.000	R4648	G1	225	N		4	116314839	Y637*	G	T	nonsense		Het	probably null			phenotype	10/08/2015
51	350523		Matn2	0.000	R4648	G1	225	N		15	34428533	I681T	T	C	missense		Het	probably damaging	1.000		phenotype	10/08/2015
52	350473		Med18	0.931	R4648	G1	225	N		4	132462963	V37D	A	T	missense		Het	possibly damaging	0.861		phenotype	10/08/2015
53	350507		Mip	0.181	R4648	G1	225	N		10	128227053	H122Q	T	A	missense		Het	probably benign	0.004		phenotype	10/08/2015
54	350492		Mmp13	0.235	R4648	G1	225	N		9	7274233	D180V	A	T	missense		Het	probably damaging	1.000		phenotype	10/08/2015
55	350508		Mpg	0.000	R4648	G1	225	N		11	32230034	C187*	C	A	nonsense		Het	probably null			phenotype	10/08/2015
56	350481		Mtmr14	0.211	R4648	G1	225	N		6	113260606	E256G	A	G	missense		Het	probably benign	0.123		phenotype	10/08/2015
57	350536		Myo7b	0.589	R4648	G1	220	N		18	31967125		C	T	splice site	5 bp	Het	probably null			phenotype	10/08/2015
58	350511		Nmt1	1.000	R4648	G1	225	N		11	103063917	V425D	T	A	missense		Het	probably damaging	1.000		phenotype	10/08/2015
59	350520		Nynrin	0.118	R4648	G1	225	N		14	55872894	Y1819*	T	A	nonsense		Het	probably null				10/08/2015
60	350462		Olfr1212	0.052	R4648	G1	225	N		2	88959212	F249I	T	A	missense		Het	probably damaging	0.994		phenotype	10/08/2015
61	350471		Olfr1330	0.141	R4648	G1	225	N		4	118893950	N289S	A	G	missense		Het	possibly damaging	0.842		phenotype	10/08/2015
62	350461		Olfr152	0.284	R4648	G1	225	N		2	87783221	V227A	T	C	missense		Het	possibly damaging	0.763		phenotype	10/08/2015
63	350474		Otof	0.211	R4648	G1	225	N		5	30383570	E875G	T	C	missense		Het	possibly damaging	0.821		phenotype	10/08/2015
64	350477		Paqr3	0.171	R4648	G1	225	N		5	97108210	R102*	T	A	nonsense		Het	probably null			phenotype	10/08/2015
65	350482		Phc1	1.000	R4648	G1	225	N		6	122321913	I699V	T	C	missense		Het	possibly damaging	0.948		phenotype	10/08/2015
66	350528		Prkdc	0.973	R4648	G1	225	N		16	15816774	D3594E	T	G	missense		Het	probably benign	0.048		phenotype	10/08/2015
67	350493		Pstpip1	0.150	R4648	G1	225	N		9	56125218	D246V	A	T	missense		Het	probably damaging	1.000		phenotype	10/08/2015
68	350464		Rbm46	0.713	R4648	G1	225	N		3	82864458	D283E	A	T	missense		Het	probably benign	0.004	0.012		10/08/2015
69	350516		Ror2	1.000	R4648	G1	225	N		13	53285500	C9*	A	T	nonsense		Het	probably null			phenotype	10/08/2015
70	350479		Setd1b	1.000	R4648	G1	214	N		5	123148112	A407V	C	T	missense		Het	unknown			phenotype	10/08/2015
71	350513		Slc26a4	0.000	R4648	G1	225	N		12	31540526	D376A	T	G	missense		Het	possibly damaging	0.899		phenotype	10/08/2015
72	350480		Smarcad1	0.221	R4648	G1	225	N		6	65067089	E215G	A	G	missense		Het	probably benign	0.041		phenotype	10/08/2015
73	350450		Spag16	0.233	R4648	G1	193	N		1	69827035	R11Q	G	A	missense		Het	probably null	0.991		phenotype	10/08/2015
74	350476		Sult1d1	0.023	R4648	G1	225	N		5	87566095	Q30L	T	A	missense		Het	probably benign	0.002		phenotype	10/08/2015
75	350534		Tbc1d5	0.154	R4648	G1	225	N		17	50736223	C746R	A	G	missense		Het	probably benign	0.000			10/08/2015
76	350521		Tdh	0.131	R4648	G1	195	N		14	63493756	L323P	A	G	missense		Het	possibly damaging	0.507			10/08/2015
77	350465		Tet2	1.000	R4648	G1	225	N		3	133488082	M197K	A	T	missense		Het	probably benign	0.024		phenotype	10/08/2015
78	350456		Tnn	0.237	R4648	G1	225	N		1	160146042	M252V	T	C	missense		Het	probably benign	0.000			10/08/2015
79	350499		Trdn	0.361	R4648	G1	225	N		10	33195981	E215*	G	T	nonsense		Het	probably null			phenotype	10/08/2015
80	350533		Trem1	0.000	R4648	G1	225	N		17	48244562	V84I	G	A	missense		Het	probably benign	0.102		phenotype	10/08/2015
81	350466		Tspan5	0.165	R4648	G1	225	N		3	138898315	F154L	T	C	missense		Het	probably damaging	0.999		phenotype	10/08/2015
82	350468		Usp45	0.201	R4648	G1	225	N		4	21825044	R647G	A	G	missense		Het	probably benign	0.117		phenotype	10/08/2015
83	350463		Usp50	0.100	R4648	G1	225	N		2	126778033	I120F	T	A	missense		Het	probably damaging	0.984			10/08/2015
84	350452		Vil1	0.469	R4648	G1	225	N		1	74432298	M746T	T	C	missense		Het	probably benign	0.000		phenotype	10/08/2015
85	350504		Washc4	0.789	R4648	G1	225	N		10	83574543	M665K	T	A	missense		Het	possibly damaging	0.711		phenotype	10/08/2015
86	350512		Zfp750	0.508	R4648	G1	225	N		11	121511880	T681A	T	C	missense		Het	probably benign	0.001		phenotype	10/08/2015
[records 1 to 86 of 86]