Incidental Mutation 'R1169:Igf1r'
| ID |
101475 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Igf1r
|
| Ensembl Gene |
ENSMUSG00000005533 |
| Gene Name |
insulin-like growth factor I receptor |
| Synonyms |
IGF-1R, line 186, A330103N21Rik, hyft, CD221 |
| MMRRC Submission |
039242-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R1169 (G1)
|
| Quality Score |
97 |
|
Status
|
Not validated
|
| Chromosome |
7 |
| Chromosomal Location |
67602575-67883416 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to T
at 67814875 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Leucine
at position 259
(V259L)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000005671
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000005671]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000005671
AA Change: V259L
PolyPhen 2
Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)
|
| SMART Domains |
Protein: ENSMUSP00000005671
Gene: ENSMUSG00000005533
AA Change: V259L
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Recep_L_domain
|
51 |
161 |
1.6e-29 |
PFAM |
|
FU
|
227 |
270 |
2.98e-12 |
SMART |
|
Pfam:Recep_L_domain
|
353 |
467 |
3.8e-32 |
PFAM |
|
FN3
|
490 |
593 |
4.67e-2 |
SMART |
|
FN3
|
612 |
815 |
1.95e-4 |
SMART |
|
FN3
|
833 |
915 |
7.4e-5 |
SMART |
|
low complexity region
|
937 |
954 |
N/A |
INTRINSIC |
|
TyrKc
|
1000 |
1268 |
8.51e-141 |
SMART |
|
low complexity region
|
1285 |
1303 |
N/A |
INTRINSIC |
|
low complexity region
|
1306 |
1319 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000207621
|
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.2%
- 10x: 95.9%
- 20x: 91.0%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]
PHENOTYPE: Targeted null mutants die at birth of respiratory failure; fetuses exhibit retarded growth, organ hypoplasia, ossification delay and nervous system and epidermal abnormalities. hyft homozygous fetuses are growth retarded and exhibit hydrops fetalis and focal hepatic ischemia. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 77 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abhd17a |
T |
C |
10: 80,419,781 (GRCm39) |
E275G |
probably damaging |
Het |
| Adam10 |
T |
A |
9: 70,653,574 (GRCm39) |
I123N |
probably damaging |
Het |
| Adam8 |
A |
T |
7: 139,563,842 (GRCm39) |
L715Q |
probably benign |
Het |
| Adcyap1r1 |
T |
A |
6: 55,471,101 (GRCm39) |
F418L |
probably damaging |
Het |
| Ankrd50 |
A |
T |
3: 38,508,401 (GRCm39) |
I1322K |
probably damaging |
Het |
| Arid4a |
G |
A |
12: 71,122,112 (GRCm39) |
S509N |
probably benign |
Het |
| Atxn7 |
T |
C |
14: 14,095,468 (GRCm38) |
S389P |
possibly damaging |
Het |
| C4b |
A |
T |
17: 34,961,946 (GRCm39) |
L100Q |
probably benign |
Het |
| Cacul1 |
G |
A |
19: 60,568,846 (GRCm39) |
A104V |
probably damaging |
Het |
| Camsap3 |
T |
C |
8: 3,653,866 (GRCm39) |
F512S |
probably damaging |
Het |
| Casp1 |
T |
C |
9: 5,299,454 (GRCm39) |
V61A |
possibly damaging |
Het |
| Cfap251 |
GGGAGGAGGAGGAGGAGGAGGA |
GGGAGGAGGAGGAGGAGGA |
5: 123,392,673 (GRCm39) |
|
probably benign |
Het |
| Chd1 |
T |
A |
17: 15,955,994 (GRCm39) |
F531Y |
probably damaging |
Het |
| Clec2h |
C |
T |
6: 128,651,758 (GRCm39) |
Q156* |
probably null |
Het |
| Clip2 |
T |
A |
5: 134,521,104 (GRCm39) |
E978V |
probably benign |
Het |
| Cnpy2 |
T |
G |
10: 128,159,465 (GRCm39) |
L34R |
probably damaging |
Het |
| Cog6 |
A |
T |
3: 52,921,265 (GRCm39) |
C114S |
probably benign |
Het |
| Col6a3 |
A |
T |
1: 90,749,736 (GRCm39) |
V366E |
possibly damaging |
Het |
| Col6a5 |
A |
G |
9: 105,774,173 (GRCm39) |
|
probably null |
Het |
| Cplx3 |
T |
C |
9: 57,517,278 (GRCm39) |
T369A |
probably damaging |
Het |
| Dmbt1 |
G |
A |
7: 130,676,254 (GRCm39) |
|
probably null |
Het |
| Dok1 |
A |
G |
6: 83,009,029 (GRCm39) |
F218L |
possibly damaging |
Het |
| Dph7 |
T |
A |
2: 24,856,583 (GRCm39) |
N178K |
probably benign |
Het |
| Enam |
A |
T |
5: 88,651,117 (GRCm39) |
E800D |
probably damaging |
Het |
| Fads3 |
A |
T |
19: 10,031,463 (GRCm39) |
Q205L |
possibly damaging |
Het |
| Fbxo44 |
T |
C |
4: 148,240,433 (GRCm39) |
H265R |
probably benign |
Het |
| Gli1 |
T |
A |
10: 127,174,320 (GRCm39) |
S24C |
probably damaging |
Het |
| Gm4894 |
T |
A |
9: 49,185,526 (GRCm39) |
C43* |
probably null |
Het |
| Gpbp1l1 |
C |
T |
4: 116,431,563 (GRCm39) |
H74Y |
possibly damaging |
Het |
| H2-Eb2 |
T |
A |
17: 34,552,331 (GRCm39) |
F59I |
possibly damaging |
Het |
| Hspa14 |
T |
C |
2: 3,499,161 (GRCm39) |
N211S |
possibly damaging |
Het |
| Ifnlr1 |
T |
G |
4: 135,432,419 (GRCm39) |
F285C |
probably benign |
Het |
| Igf2bp2 |
A |
T |
16: 21,897,480 (GRCm39) |
Y244* |
probably null |
Het |
| Ighg2c |
A |
T |
12: 113,249,572 (GRCm39) |
|
probably benign |
Het |
| Ighv8-14 |
A |
T |
12: 115,772,075 (GRCm39) |
|
probably null |
Het |
| Iqsec2 |
A |
G |
X: 150,927,727 (GRCm39) |
S87G |
probably benign |
Het |
| Itsn2 |
A |
G |
12: 4,689,694 (GRCm39) |
K589R |
probably damaging |
Het |
| Khdc1a |
A |
C |
1: 21,420,495 (GRCm39) |
E38D |
possibly damaging |
Het |
| Krt42 |
T |
G |
11: 100,154,171 (GRCm39) |
|
probably null |
Het |
| Lpo |
T |
C |
11: 87,708,143 (GRCm39) |
N183S |
possibly damaging |
Het |
| Lrrc3 |
T |
A |
10: 77,736,764 (GRCm39) |
Y224F |
probably damaging |
Het |
| Ly6g6f |
T |
A |
17: 35,302,240 (GRCm39) |
D99V |
probably damaging |
Het |
| Lyplal1 |
T |
C |
1: 185,846,531 (GRCm39) |
I42V |
probably benign |
Het |
| Mis18bp1 |
G |
A |
12: 65,190,057 (GRCm39) |
Q793* |
probably null |
Het |
| Myh10 |
T |
G |
11: 68,653,667 (GRCm39) |
M346R |
probably damaging |
Het |
| Nav1 |
G |
T |
1: 135,382,943 (GRCm39) |
H1256Q |
probably damaging |
Het |
| Nbea |
A |
G |
3: 55,875,744 (GRCm39) |
V1642A |
probably benign |
Het |
| Or4d6 |
C |
T |
19: 12,086,853 (GRCm39) |
R19H |
probably benign |
Het |
| Or8b12i |
T |
C |
9: 20,082,354 (GRCm39) |
N171S |
probably benign |
Het |
| Or8i2 |
A |
G |
2: 86,852,061 (GRCm39) |
F276L |
probably damaging |
Het |
| Or8k28 |
A |
G |
2: 86,285,931 (GRCm39) |
I228T |
possibly damaging |
Het |
| Orm3 |
G |
A |
4: 63,276,085 (GRCm39) |
V166M |
probably damaging |
Het |
| Oxct1 |
T |
A |
15: 4,120,708 (GRCm39) |
I264N |
probably damaging |
Het |
| Paox |
G |
A |
7: 139,706,244 (GRCm39) |
V55I |
probably benign |
Het |
| Pde4d |
C |
A |
13: 110,087,462 (GRCm39) |
|
probably null |
Het |
| Pnliprp1 |
A |
G |
19: 58,723,383 (GRCm39) |
N258S |
probably damaging |
Het |
| Potegl |
A |
G |
2: 23,146,994 (GRCm39) |
K275E |
possibly damaging |
Het |
| Prl7b1 |
C |
A |
13: 27,790,887 (GRCm39) |
R66L |
possibly damaging |
Het |
| Ptpre |
G |
T |
7: 135,269,341 (GRCm39) |
C261F |
probably benign |
Het |
| Rho |
C |
G |
6: 115,909,199 (GRCm39) |
N78K |
probably damaging |
Het |
| Rnf17 |
A |
G |
14: 56,751,622 (GRCm39) |
N1487D |
possibly damaging |
Het |
| Ryr3 |
G |
A |
2: 112,563,359 (GRCm39) |
T2922I |
probably benign |
Het |
| Saxo2 |
A |
C |
7: 82,284,379 (GRCm39) |
F160V |
possibly damaging |
Het |
| Sbf2 |
A |
T |
7: 109,909,391 (GRCm39) |
Y1786N |
probably benign |
Het |
| Sdad1 |
A |
T |
5: 92,446,092 (GRCm39) |
V280E |
probably benign |
Het |
| Sgsm1 |
T |
C |
5: 113,427,351 (GRCm39) |
D90G |
probably damaging |
Het |
| Siglec1 |
A |
T |
2: 130,916,747 (GRCm39) |
D1169E |
probably damaging |
Het |
| Sim1 |
T |
A |
10: 50,857,618 (GRCm39) |
V456E |
probably benign |
Het |
| Skint8 |
T |
A |
4: 111,785,710 (GRCm39) |
I52N |
possibly damaging |
Het |
| Slc27a1 |
C |
A |
8: 72,033,297 (GRCm39) |
R280S |
probably benign |
Het |
| Slc9a3 |
G |
A |
13: 74,298,862 (GRCm39) |
V94I |
probably damaging |
Het |
| Sorcs2 |
C |
A |
5: 36,185,269 (GRCm39) |
V936L |
possibly damaging |
Het |
| Syce1 |
A |
G |
7: 140,358,120 (GRCm39) |
F255S |
probably benign |
Het |
| Tmc7 |
G |
A |
7: 118,150,483 (GRCm39) |
S350L |
probably benign |
Het |
| Tmem200a |
T |
A |
10: 25,870,246 (GRCm39) |
I8F |
probably damaging |
Het |
| Trip6 |
T |
C |
5: 137,310,182 (GRCm39) |
H322R |
probably benign |
Het |
| Vmn2r72 |
A |
T |
7: 85,400,517 (GRCm39) |
N177K |
probably benign |
Het |
|
| Other mutations in Igf1r |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00742:Igf1r
|
APN |
7 |
67,839,771 (GRCm39) |
missense |
probably benign |
|
|
IGL00837:Igf1r
|
APN |
7 |
67,851,100 (GRCm39) |
splice site |
probably benign |
|
|
IGL01515:Igf1r
|
APN |
7 |
67,857,200 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01572:Igf1r
|
APN |
7 |
67,843,189 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02100:Igf1r
|
APN |
7 |
67,839,706 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL02506:Igf1r
|
APN |
7 |
67,843,144 (GRCm39) |
missense |
probably benign |
|
|
IGL02672:Igf1r
|
APN |
7 |
67,839,781 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL02701:Igf1r
|
APN |
7 |
67,850,997 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
IGL02742:Igf1r
|
APN |
7 |
67,839,739 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL03073:Igf1r
|
APN |
7 |
67,864,791 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03257:Igf1r
|
APN |
7 |
67,864,688 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Frufru
|
UTSW |
7 |
67,653,911 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Hungarian
|
UTSW |
7 |
67,864,745 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Mimi
|
UTSW |
7 |
67,844,774 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
Piroshka
|
UTSW |
7 |
67,857,084 (GRCm39) |
nonsense |
probably null |
|
|
Romanian
|
UTSW |
7 |
67,653,885 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
Sublime
|
UTSW |
7 |
67,653,927 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Toy
|
UTSW |
7 |
67,653,720 (GRCm39) |
missense |
probably damaging |
1.00 |
|
BB009:Igf1r
|
UTSW |
7 |
67,861,802 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
BB019:Igf1r
|
UTSW |
7 |
67,861,802 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
FR4548:Igf1r
|
UTSW |
7 |
67,875,934 (GRCm39) |
small insertion |
probably benign |
|
|
FR4737:Igf1r
|
UTSW |
7 |
67,875,929 (GRCm39) |
small insertion |
probably benign |
|
|
FR4976:Igf1r
|
UTSW |
7 |
67,875,934 (GRCm39) |
small insertion |
probably benign |
|
|
FR4976:Igf1r
|
UTSW |
7 |
67,875,929 (GRCm39) |
small insertion |
probably benign |
|
|
PIT4445001:Igf1r
|
UTSW |
7 |
67,857,211 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0003:Igf1r
|
UTSW |
7 |
67,814,990 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0184:Igf1r
|
UTSW |
7 |
67,875,941 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R0538:Igf1r
|
UTSW |
7 |
67,857,574 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0632:Igf1r
|
UTSW |
7 |
67,814,903 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0727:Igf1r
|
UTSW |
7 |
67,861,906 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0750:Igf1r
|
UTSW |
7 |
67,861,839 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1104:Igf1r
|
UTSW |
7 |
67,844,774 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R1348:Igf1r
|
UTSW |
7 |
67,868,216 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1471:Igf1r
|
UTSW |
7 |
67,653,585 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1580:Igf1r
|
UTSW |
7 |
67,857,617 (GRCm39) |
missense |
probably benign |
|
|
R1745:Igf1r
|
UTSW |
7 |
67,819,661 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1772:Igf1r
|
UTSW |
7 |
67,844,822 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1789:Igf1r
|
UTSW |
7 |
67,864,681 (GRCm39) |
nonsense |
probably null |
|
|
R1823:Igf1r
|
UTSW |
7 |
67,844,729 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R1902:Igf1r
|
UTSW |
7 |
67,850,997 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R1962:Igf1r
|
UTSW |
7 |
67,857,023 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2179:Igf1r
|
UTSW |
7 |
67,653,698 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2215:Igf1r
|
UTSW |
7 |
67,814,982 (GRCm39) |
missense |
probably benign |
|
|
R2221:Igf1r
|
UTSW |
7 |
67,851,710 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2233:Igf1r
|
UTSW |
7 |
67,861,828 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2234:Igf1r
|
UTSW |
7 |
67,861,828 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2235:Igf1r
|
UTSW |
7 |
67,861,828 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3023:Igf1r
|
UTSW |
7 |
67,833,147 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4044:Igf1r
|
UTSW |
7 |
67,839,810 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R4226:Igf1r
|
UTSW |
7 |
67,844,826 (GRCm39) |
nonsense |
probably null |
|
|
R4387:Igf1r
|
UTSW |
7 |
67,819,757 (GRCm39) |
missense |
probably benign |
|
|
R4388:Igf1r
|
UTSW |
7 |
67,819,757 (GRCm39) |
missense |
probably benign |
|
|
R4728:Igf1r
|
UTSW |
7 |
67,839,372 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4781:Igf1r
|
UTSW |
7 |
67,814,947 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R5254:Igf1r
|
UTSW |
7 |
67,857,067 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5278:Igf1r
|
UTSW |
7 |
67,843,166 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R5510:Igf1r
|
UTSW |
7 |
67,843,107 (GRCm39) |
missense |
probably benign |
0.19 |
|
R5522:Igf1r
|
UTSW |
7 |
67,833,258 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5527:Igf1r
|
UTSW |
7 |
67,857,569 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5761:Igf1r
|
UTSW |
7 |
67,857,001 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5849:Igf1r
|
UTSW |
7 |
67,839,781 (GRCm39) |
missense |
probably benign |
|
|
R6189:Igf1r
|
UTSW |
7 |
67,857,084 (GRCm39) |
nonsense |
probably null |
|
|
R6262:Igf1r
|
UTSW |
7 |
67,653,720 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6285:Igf1r
|
UTSW |
7 |
67,653,885 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6318:Igf1r
|
UTSW |
7 |
67,814,981 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6365:Igf1r
|
UTSW |
7 |
67,839,798 (GRCm39) |
missense |
probably benign |
0.26 |
|
R6377:Igf1r
|
UTSW |
7 |
67,850,998 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6831:Igf1r
|
UTSW |
7 |
67,857,067 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R6848:Igf1r
|
UTSW |
7 |
67,653,927 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6902:Igf1r
|
UTSW |
7 |
67,653,911 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7193:Igf1r
|
UTSW |
7 |
67,836,905 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7373:Igf1r
|
UTSW |
7 |
67,844,826 (GRCm39) |
nonsense |
probably null |
|
|
R7442:Igf1r
|
UTSW |
7 |
67,823,026 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7903:Igf1r
|
UTSW |
7 |
67,834,500 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7923:Igf1r
|
UTSW |
7 |
67,839,849 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7932:Igf1r
|
UTSW |
7 |
67,861,802 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R8368:Igf1r
|
UTSW |
7 |
67,836,796 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8458:Igf1r
|
UTSW |
7 |
67,845,377 (GRCm39) |
missense |
probably benign |
|
|
R8539:Igf1r
|
UTSW |
7 |
67,653,596 (GRCm39) |
missense |
probably benign |
0.06 |
|
R8704:Igf1r
|
UTSW |
7 |
67,819,802 (GRCm39) |
splice site |
probably benign |
|
|
R8746:Igf1r
|
UTSW |
7 |
67,864,745 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8829:Igf1r
|
UTSW |
7 |
67,875,769 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8832:Igf1r
|
UTSW |
7 |
67,875,769 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8859:Igf1r
|
UTSW |
7 |
67,833,211 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R9057:Igf1r
|
UTSW |
7 |
67,833,186 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9243:Igf1r
|
UTSW |
7 |
67,861,775 (GRCm39) |
missense |
probably benign |
0.11 |
|
R9342:Igf1r
|
UTSW |
7 |
67,844,746 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9412:Igf1r
|
UTSW |
7 |
67,857,001 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9525:Igf1r
|
UTSW |
7 |
67,864,682 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9727:Igf1r
|
UTSW |
7 |
67,857,554 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9730:Igf1r
|
UTSW |
7 |
67,839,423 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9779:Igf1r
|
UTSW |
7 |
67,654,065 (GRCm39) |
missense |
probably damaging |
1.00 |
|
RF025:Igf1r
|
UTSW |
7 |
67,875,927 (GRCm39) |
small insertion |
probably benign |
|
|
RF032:Igf1r
|
UTSW |
7 |
67,875,927 (GRCm39) |
small insertion |
probably benign |
|
|
RF034:Igf1r
|
UTSW |
7 |
67,875,924 (GRCm39) |
small insertion |
probably benign |
|
|
RF037:Igf1r
|
UTSW |
7 |
67,875,924 (GRCm39) |
small insertion |
probably benign |
|
|
RF039:Igf1r
|
UTSW |
7 |
67,875,924 (GRCm39) |
small insertion |
probably benign |
|
|
RF044:Igf1r
|
UTSW |
7 |
67,875,927 (GRCm39) |
small insertion |
probably benign |
|
|
Z1186:Igf1r
|
UTSW |
7 |
67,875,916 (GRCm39) |
small insertion |
probably benign |
|
|
Z1186:Igf1r
|
UTSW |
7 |
67,875,930 (GRCm39) |
small insertion |
probably benign |
|
|
Z1186:Igf1r
|
UTSW |
7 |
67,875,928 (GRCm39) |
small insertion |
probably benign |
|
|
Z1186:Igf1r
|
UTSW |
7 |
67,875,922 (GRCm39) |
small insertion |
probably benign |
|
|
Z1186:Igf1r
|
UTSW |
7 |
67,875,917 (GRCm39) |
small insertion |
probably benign |
|
|
Z1191:Igf1r
|
UTSW |
7 |
67,875,918 (GRCm39) |
small insertion |
probably benign |
|
|
Z1191:Igf1r
|
UTSW |
7 |
67,875,917 (GRCm39) |
small insertion |
probably benign |
|
|
Z1191:Igf1r
|
UTSW |
7 |
67,875,921 (GRCm39) |
small insertion |
probably benign |
|
|
| Predicted Primers |
|
| Posted On |
2014-01-15 |
Incidental Mutation