Incidental Mutation 'R1169:Pde4d'
| ID |
101553 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Pde4d
|
| Ensembl Gene |
ENSMUSG00000021699 |
| Gene Name |
phosphodiesterase 4D, cAMP specific |
| Synonyms |
9630011N22Rik, dunce, Dpde3 |
| MMRRC Submission |
039242-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R1169 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
13 |
| Chromosomal Location |
108790711-110092503 bp(+) (GRCm39) |
| Type of Mutation |
splice site |
| DNA Base Change (assembly) |
C to A
at 110087462 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000136485
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000074103]
[ENSMUST00000079975]
[ENSMUST00000117420]
[ENSMUST00000117420]
[ENSMUST00000117879]
[ENSMUST00000117879]
[ENSMUST00000119507]
[ENSMUST00000119507]
[ENSMUST00000119672]
[ENSMUST00000120664]
[ENSMUST00000120664]
[ENSMUST00000120671]
[ENSMUST00000120671]
[ENSMUST00000122041]
[ENSMUST00000135275]
[ENSMUST00000135275]
[ENSMUST00000177907]
|
| AlphaFold |
Q01063 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000074103
|
| SMART Domains |
Protein: ENSMUSP00000073742
Gene: ENSMUSG00000021699
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
8 |
18 |
N/A |
INTRINSIC |
|
HDc
|
329 |
504 |
1.12e-2 |
SMART |
|
low complexity region
|
652 |
667 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000079975
|
| SMART Domains |
Protein: ENSMUSP00000078891
Gene: ENSMUSG00000021699
| Domain | Start | End | E-Value | Type |
|---|
|
HDc
|
349 |
524 |
1.12e-2 |
SMART |
|
low complexity region
|
672 |
687 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000117420
|
| SMART Domains |
Protein: ENSMUSP00000113610
Gene: ENSMUSG00000021699
| Domain | Start | End | E-Value | Type |
|---|
|
HDc
|
168 |
343 |
1.12e-2 |
SMART |
|
low complexity region
|
491 |
506 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000117420
|
| SMART Domains |
Protein: ENSMUSP00000113610
Gene: ENSMUSG00000021699
| Domain | Start | End | E-Value | Type |
|---|
|
HDc
|
168 |
343 |
1.12e-2 |
SMART |
|
low complexity region
|
491 |
506 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000117879
|
| SMART Domains |
Protein: ENSMUSP00000112774
Gene: ENSMUSG00000021699
| Domain | Start | End | E-Value | Type |
|---|
|
HDc
|
155 |
330 |
1.12e-2 |
SMART |
|
low complexity region
|
478 |
493 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000117879
|
| SMART Domains |
Protein: ENSMUSP00000112774
Gene: ENSMUSG00000021699
| Domain | Start | End | E-Value | Type |
|---|
|
HDc
|
155 |
330 |
1.12e-2 |
SMART |
|
low complexity region
|
478 |
493 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000119507
|
| SMART Domains |
Protein: ENSMUSP00000114089
Gene: ENSMUSG00000021699
| Domain | Start | End | E-Value | Type |
|---|
|
HDc
|
354 |
529 |
1.12e-2 |
SMART |
|
low complexity region
|
677 |
692 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000119507
|
| SMART Domains |
Protein: ENSMUSP00000114089
Gene: ENSMUSG00000021699
| Domain | Start | End | E-Value | Type |
|---|
|
HDc
|
354 |
529 |
1.12e-2 |
SMART |
|
low complexity region
|
677 |
692 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000119672
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000120664
|
| SMART Domains |
Protein: ENSMUSP00000113024
Gene: ENSMUSG00000021699
| Domain | Start | End | E-Value | Type |
|---|
|
HDc
|
235 |
410 |
1.12e-2 |
SMART |
|
low complexity region
|
558 |
573 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000120664
|
| SMART Domains |
Protein: ENSMUSP00000113024
Gene: ENSMUSG00000021699
| Domain | Start | End | E-Value | Type |
|---|
|
HDc
|
235 |
410 |
1.12e-2 |
SMART |
|
low complexity region
|
558 |
573 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000120671
|
| SMART Domains |
Protein: ENSMUSP00000112991
Gene: ENSMUSG00000021699
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
45 |
84 |
N/A |
INTRINSIC |
|
HDc
|
454 |
629 |
1.12e-2 |
SMART |
|
low complexity region
|
777 |
792 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000120671
|
| SMART Domains |
Protein: ENSMUSP00000112991
Gene: ENSMUSG00000021699
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
45 |
84 |
N/A |
INTRINSIC |
|
HDc
|
454 |
629 |
1.12e-2 |
SMART |
|
low complexity region
|
777 |
792 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000122041
|
| SMART Domains |
Protein: ENSMUSP00000113488
Gene: ENSMUSG00000021699
| Domain | Start | End | E-Value | Type |
|---|
|
HDc
|
398 |
573 |
1.12e-2 |
SMART |
|
low complexity region
|
721 |
736 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000135275
|
| SMART Domains |
Protein: ENSMUSP00000119583
Gene: ENSMUSG00000021699
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
25 |
N/A |
INTRINSIC |
|
HDc
|
351 |
526 |
1.12e-2 |
SMART |
|
low complexity region
|
674 |
689 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000135275
|
| SMART Domains |
Protein: ENSMUSP00000119583
Gene: ENSMUSG00000021699
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
25 |
N/A |
INTRINSIC |
|
HDc
|
351 |
526 |
1.12e-2 |
SMART |
|
low complexity region
|
674 |
689 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000153234
|
| SMART Domains |
Protein: ENSMUSP00000121592
Gene: ENSMUSG00000021699
| Domain | Start | End | E-Value | Type |
|---|
|
PDB:1E9K|A
|
22 |
59 |
9e-18 |
PDB |
|
low complexity region
|
69 |
85 |
N/A |
INTRINSIC |
|
HDc
|
405 |
580 |
1.12e-2 |
SMART |
|
low complexity region
|
728 |
743 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000153234
|
| SMART Domains |
Protein: ENSMUSP00000121592
Gene: ENSMUSG00000021699
| Domain | Start | End | E-Value | Type |
|---|
|
PDB:1E9K|A
|
22 |
59 |
9e-18 |
PDB |
|
low complexity region
|
69 |
85 |
N/A |
INTRINSIC |
|
HDc
|
405 |
580 |
1.12e-2 |
SMART |
|
low complexity region
|
728 |
743 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000177907
|
| SMART Domains |
Protein: ENSMUSP00000136485
Gene: ENSMUSG00000021699
| Domain | Start | End | E-Value | Type |
|---|
|
HDc
|
398 |
573 |
1.12e-2 |
SMART |
|
low complexity region
|
721 |
736 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000155459
|
| SMART Domains |
Protein: ENSMUSP00000114945
Gene: ENSMUSG00000021699
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:PDEase_I
|
121 |
189 |
2.6e-23 |
PFAM |
|
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.2%
- 10x: 95.9%
- 20x: 91.0%
|
| Validation Efficiency |
|
| MGI Phenotype |
PHENOTYPE: Homozygotes for targeted null mutations exhibit delayed growth, female infertility associated with impaired ovulation, and reduced postnatal viability. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 77 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abhd17a |
T |
C |
10: 80,419,781 (GRCm39) |
E275G |
probably damaging |
Het |
| Adam10 |
T |
A |
9: 70,653,574 (GRCm39) |
I123N |
probably damaging |
Het |
| Adam8 |
A |
T |
7: 139,563,842 (GRCm39) |
L715Q |
probably benign |
Het |
| Adcyap1r1 |
T |
A |
6: 55,471,101 (GRCm39) |
F418L |
probably damaging |
Het |
| Ankrd50 |
A |
T |
3: 38,508,401 (GRCm39) |
I1322K |
probably damaging |
Het |
| Arid4a |
G |
A |
12: 71,122,112 (GRCm39) |
S509N |
probably benign |
Het |
| Atxn7 |
T |
C |
14: 14,095,468 (GRCm38) |
S389P |
possibly damaging |
Het |
| C4b |
A |
T |
17: 34,961,946 (GRCm39) |
L100Q |
probably benign |
Het |
| Cacul1 |
G |
A |
19: 60,568,846 (GRCm39) |
A104V |
probably damaging |
Het |
| Camsap3 |
T |
C |
8: 3,653,866 (GRCm39) |
F512S |
probably damaging |
Het |
| Casp1 |
T |
C |
9: 5,299,454 (GRCm39) |
V61A |
possibly damaging |
Het |
| Cfap251 |
GGGAGGAGGAGGAGGAGGAGGA |
GGGAGGAGGAGGAGGAGGA |
5: 123,392,673 (GRCm39) |
|
probably benign |
Het |
| Chd1 |
T |
A |
17: 15,955,994 (GRCm39) |
F531Y |
probably damaging |
Het |
| Clec2h |
C |
T |
6: 128,651,758 (GRCm39) |
Q156* |
probably null |
Het |
| Clip2 |
T |
A |
5: 134,521,104 (GRCm39) |
E978V |
probably benign |
Het |
| Cnpy2 |
T |
G |
10: 128,159,465 (GRCm39) |
L34R |
probably damaging |
Het |
| Cog6 |
A |
T |
3: 52,921,265 (GRCm39) |
C114S |
probably benign |
Het |
| Col6a3 |
A |
T |
1: 90,749,736 (GRCm39) |
V366E |
possibly damaging |
Het |
| Col6a5 |
A |
G |
9: 105,774,173 (GRCm39) |
|
probably null |
Het |
| Cplx3 |
T |
C |
9: 57,517,278 (GRCm39) |
T369A |
probably damaging |
Het |
| Dmbt1 |
G |
A |
7: 130,676,254 (GRCm39) |
|
probably null |
Het |
| Dok1 |
A |
G |
6: 83,009,029 (GRCm39) |
F218L |
possibly damaging |
Het |
| Dph7 |
T |
A |
2: 24,856,583 (GRCm39) |
N178K |
probably benign |
Het |
| Enam |
A |
T |
5: 88,651,117 (GRCm39) |
E800D |
probably damaging |
Het |
| Fads3 |
A |
T |
19: 10,031,463 (GRCm39) |
Q205L |
possibly damaging |
Het |
| Fbxo44 |
T |
C |
4: 148,240,433 (GRCm39) |
H265R |
probably benign |
Het |
| Gli1 |
T |
A |
10: 127,174,320 (GRCm39) |
S24C |
probably damaging |
Het |
| Gm4894 |
T |
A |
9: 49,185,526 (GRCm39) |
C43* |
probably null |
Het |
| Gpbp1l1 |
C |
T |
4: 116,431,563 (GRCm39) |
H74Y |
possibly damaging |
Het |
| H2-Eb2 |
T |
A |
17: 34,552,331 (GRCm39) |
F59I |
possibly damaging |
Het |
| Hspa14 |
T |
C |
2: 3,499,161 (GRCm39) |
N211S |
possibly damaging |
Het |
| Ifnlr1 |
T |
G |
4: 135,432,419 (GRCm39) |
F285C |
probably benign |
Het |
| Igf1r |
G |
T |
7: 67,814,875 (GRCm39) |
V259L |
probably benign |
Het |
| Igf2bp2 |
A |
T |
16: 21,897,480 (GRCm39) |
Y244* |
probably null |
Het |
| Ighg2c |
A |
T |
12: 113,249,572 (GRCm39) |
|
probably benign |
Het |
| Ighv8-14 |
A |
T |
12: 115,772,075 (GRCm39) |
|
probably null |
Het |
| Iqsec2 |
A |
G |
X: 150,927,727 (GRCm39) |
S87G |
probably benign |
Het |
| Itsn2 |
A |
G |
12: 4,689,694 (GRCm39) |
K589R |
probably damaging |
Het |
| Khdc1a |
A |
C |
1: 21,420,495 (GRCm39) |
E38D |
possibly damaging |
Het |
| Krt42 |
T |
G |
11: 100,154,171 (GRCm39) |
|
probably null |
Het |
| Lpo |
T |
C |
11: 87,708,143 (GRCm39) |
N183S |
possibly damaging |
Het |
| Lrrc3 |
T |
A |
10: 77,736,764 (GRCm39) |
Y224F |
probably damaging |
Het |
| Ly6g6f |
T |
A |
17: 35,302,240 (GRCm39) |
D99V |
probably damaging |
Het |
| Lyplal1 |
T |
C |
1: 185,846,531 (GRCm39) |
I42V |
probably benign |
Het |
| Mis18bp1 |
G |
A |
12: 65,190,057 (GRCm39) |
Q793* |
probably null |
Het |
| Myh10 |
T |
G |
11: 68,653,667 (GRCm39) |
M346R |
probably damaging |
Het |
| Nav1 |
G |
T |
1: 135,382,943 (GRCm39) |
H1256Q |
probably damaging |
Het |
| Nbea |
A |
G |
3: 55,875,744 (GRCm39) |
V1642A |
probably benign |
Het |
| Or4d6 |
C |
T |
19: 12,086,853 (GRCm39) |
R19H |
probably benign |
Het |
| Or8b12i |
T |
C |
9: 20,082,354 (GRCm39) |
N171S |
probably benign |
Het |
| Or8i2 |
A |
G |
2: 86,852,061 (GRCm39) |
F276L |
probably damaging |
Het |
| Or8k28 |
A |
G |
2: 86,285,931 (GRCm39) |
I228T |
possibly damaging |
Het |
| Orm3 |
G |
A |
4: 63,276,085 (GRCm39) |
V166M |
probably damaging |
Het |
| Oxct1 |
T |
A |
15: 4,120,708 (GRCm39) |
I264N |
probably damaging |
Het |
| Paox |
G |
A |
7: 139,706,244 (GRCm39) |
V55I |
probably benign |
Het |
| Pnliprp1 |
A |
G |
19: 58,723,383 (GRCm39) |
N258S |
probably damaging |
Het |
| Potegl |
A |
G |
2: 23,146,994 (GRCm39) |
K275E |
possibly damaging |
Het |
| Prl7b1 |
C |
A |
13: 27,790,887 (GRCm39) |
R66L |
possibly damaging |
Het |
| Ptpre |
G |
T |
7: 135,269,341 (GRCm39) |
C261F |
probably benign |
Het |
| Rho |
C |
G |
6: 115,909,199 (GRCm39) |
N78K |
probably damaging |
Het |
| Rnf17 |
A |
G |
14: 56,751,622 (GRCm39) |
N1487D |
possibly damaging |
Het |
| Ryr3 |
G |
A |
2: 112,563,359 (GRCm39) |
T2922I |
probably benign |
Het |
| Saxo2 |
A |
C |
7: 82,284,379 (GRCm39) |
F160V |
possibly damaging |
Het |
| Sbf2 |
A |
T |
7: 109,909,391 (GRCm39) |
Y1786N |
probably benign |
Het |
| Sdad1 |
A |
T |
5: 92,446,092 (GRCm39) |
V280E |
probably benign |
Het |
| Sgsm1 |
T |
C |
5: 113,427,351 (GRCm39) |
D90G |
probably damaging |
Het |
| Siglec1 |
A |
T |
2: 130,916,747 (GRCm39) |
D1169E |
probably damaging |
Het |
| Sim1 |
T |
A |
10: 50,857,618 (GRCm39) |
V456E |
probably benign |
Het |
| Skint8 |
T |
A |
4: 111,785,710 (GRCm39) |
I52N |
possibly damaging |
Het |
| Slc27a1 |
C |
A |
8: 72,033,297 (GRCm39) |
R280S |
probably benign |
Het |
| Slc9a3 |
G |
A |
13: 74,298,862 (GRCm39) |
V94I |
probably damaging |
Het |
| Sorcs2 |
C |
A |
5: 36,185,269 (GRCm39) |
V936L |
possibly damaging |
Het |
| Syce1 |
A |
G |
7: 140,358,120 (GRCm39) |
F255S |
probably benign |
Het |
| Tmc7 |
G |
A |
7: 118,150,483 (GRCm39) |
S350L |
probably benign |
Het |
| Tmem200a |
T |
A |
10: 25,870,246 (GRCm39) |
I8F |
probably damaging |
Het |
| Trip6 |
T |
C |
5: 137,310,182 (GRCm39) |
H322R |
probably benign |
Het |
| Vmn2r72 |
A |
T |
7: 85,400,517 (GRCm39) |
N177K |
probably benign |
Het |
|
| Other mutations in Pde4d |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00465:Pde4d
|
APN |
13 |
110,073,221 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
IGL00792:Pde4d
|
APN |
13 |
110,071,929 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
IGL01014:Pde4d
|
APN |
13 |
110,086,036 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01660:Pde4d
|
APN |
13 |
110,074,606 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02233:Pde4d
|
APN |
13 |
109,877,084 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02405:Pde4d
|
APN |
13 |
108,996,743 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02544:Pde4d
|
APN |
13 |
109,877,057 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02885:Pde4d
|
APN |
13 |
110,084,795 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03286:Pde4d
|
APN |
13 |
110,091,040 (GRCm39) |
unclassified |
probably benign |
|
|
IGL03406:Pde4d
|
APN |
13 |
110,091,125 (GRCm39) |
unclassified |
probably benign |
|
|
Heliosphere
|
UTSW |
13 |
109,253,476 (GRCm39) |
missense |
probably benign |
|
|
Stubbs
|
UTSW |
13 |
109,909,256 (GRCm39) |
intron |
probably benign |
|
|
IGL03055:Pde4d
|
UTSW |
13 |
110,071,879 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0020:Pde4d
|
UTSW |
13 |
110,091,104 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R0020:Pde4d
|
UTSW |
13 |
110,091,104 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R0054:Pde4d
|
UTSW |
13 |
109,876,955 (GRCm39) |
missense |
probably benign |
0.23 |
|
R0054:Pde4d
|
UTSW |
13 |
109,876,955 (GRCm39) |
missense |
probably benign |
0.23 |
|
R0357:Pde4d
|
UTSW |
13 |
110,087,802 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R0482:Pde4d
|
UTSW |
13 |
110,073,244 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0689:Pde4d
|
UTSW |
13 |
109,877,078 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R0884:Pde4d
|
UTSW |
13 |
110,087,474 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1225:Pde4d
|
UTSW |
13 |
110,086,755 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1246:Pde4d
|
UTSW |
13 |
110,087,507 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1344:Pde4d
|
UTSW |
13 |
110,086,921 (GRCm39) |
nonsense |
probably null |
|
|
R1351:Pde4d
|
UTSW |
13 |
110,087,809 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R1371:Pde4d
|
UTSW |
13 |
109,253,595 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1418:Pde4d
|
UTSW |
13 |
110,086,921 (GRCm39) |
nonsense |
probably null |
|
|
R2197:Pde4d
|
UTSW |
13 |
110,084,924 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2440:Pde4d
|
UTSW |
13 |
110,063,731 (GRCm39) |
intron |
probably benign |
|
|
R3114:Pde4d
|
UTSW |
13 |
110,084,792 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3115:Pde4d
|
UTSW |
13 |
110,084,792 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3722:Pde4d
|
UTSW |
13 |
110,087,866 (GRCm39) |
nonsense |
probably null |
|
|
R3742:Pde4d
|
UTSW |
13 |
109,877,013 (GRCm39) |
missense |
probably benign |
0.42 |
|
R3797:Pde4d
|
UTSW |
13 |
109,769,431 (GRCm39) |
missense |
probably benign |
0.29 |
|
R3983:Pde4d
|
UTSW |
13 |
109,876,940 (GRCm39) |
missense |
probably benign |
0.23 |
|
R4618:Pde4d
|
UTSW |
13 |
110,070,411 (GRCm39) |
missense |
probably benign |
0.13 |
|
R4768:Pde4d
|
UTSW |
13 |
110,070,408 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4795:Pde4d
|
UTSW |
13 |
110,074,705 (GRCm39) |
intron |
probably benign |
|
|
R4824:Pde4d
|
UTSW |
13 |
109,253,400 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4942:Pde4d
|
UTSW |
13 |
108,996,733 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4984:Pde4d
|
UTSW |
13 |
109,876,998 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5180:Pde4d
|
UTSW |
13 |
109,877,007 (GRCm39) |
missense |
probably benign |
0.13 |
|
R5267:Pde4d
|
UTSW |
13 |
109,397,343 (GRCm39) |
intron |
probably benign |
|
|
R5311:Pde4d
|
UTSW |
13 |
109,769,399 (GRCm39) |
missense |
probably benign |
|
|
R5311:Pde4d
|
UTSW |
13 |
109,769,398 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5376:Pde4d
|
UTSW |
13 |
109,909,178 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5551:Pde4d
|
UTSW |
13 |
110,084,930 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5753:Pde4d
|
UTSW |
13 |
109,909,256 (GRCm39) |
intron |
probably benign |
|
|
R5754:Pde4d
|
UTSW |
13 |
110,074,547 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5838:Pde4d
|
UTSW |
13 |
109,876,976 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5864:Pde4d
|
UTSW |
13 |
110,074,582 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6039:Pde4d
|
UTSW |
13 |
110,084,876 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6039:Pde4d
|
UTSW |
13 |
110,084,876 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6049:Pde4d
|
UTSW |
13 |
109,169,119 (GRCm39) |
nonsense |
probably null |
|
|
R6214:Pde4d
|
UTSW |
13 |
110,085,967 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6215:Pde4d
|
UTSW |
13 |
110,085,967 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6273:Pde4d
|
UTSW |
13 |
110,086,755 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6431:Pde4d
|
UTSW |
13 |
109,738,320 (GRCm39) |
splice site |
probably null |
|
|
R6501:Pde4d
|
UTSW |
13 |
109,253,476 (GRCm39) |
missense |
probably benign |
|
|
R6534:Pde4d
|
UTSW |
13 |
109,769,435 (GRCm39) |
missense |
probably benign |
0.05 |
|
R6709:Pde4d
|
UTSW |
13 |
110,084,813 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6722:Pde4d
|
UTSW |
13 |
109,769,432 (GRCm39) |
nonsense |
probably null |
|
|
R7164:Pde4d
|
UTSW |
13 |
109,169,222 (GRCm39) |
missense |
probably benign |
|
|
R7222:Pde4d
|
UTSW |
13 |
109,894,113 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7417:Pde4d
|
UTSW |
13 |
109,769,322 (GRCm39) |
splice site |
probably null |
|
|
R7489:Pde4d
|
UTSW |
13 |
109,253,301 (GRCm39) |
missense |
unknown |
|
|
R7563:Pde4d
|
UTSW |
13 |
110,087,541 (GRCm39) |
missense |
probably benign |
0.37 |
|
R7861:Pde4d
|
UTSW |
13 |
110,071,858 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8167:Pde4d
|
UTSW |
13 |
109,578,855 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8197:Pde4d
|
UTSW |
13 |
110,084,870 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8469:Pde4d
|
UTSW |
13 |
108,996,722 (GRCm39) |
missense |
probably benign |
|
|
R8715:Pde4d
|
UTSW |
13 |
110,071,876 (GRCm39) |
missense |
probably benign |
0.29 |
|
R8926:Pde4d
|
UTSW |
13 |
110,074,625 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9054:Pde4d
|
UTSW |
13 |
110,071,924 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9406:Pde4d
|
UTSW |
13 |
109,877,064 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9516:Pde4d
|
UTSW |
13 |
109,397,196 (GRCm39) |
missense |
|
|
|
R9526:Pde4d
|
UTSW |
13 |
110,071,915 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
|
| Posted On |
2014-01-15 |
Incidental Mutation