Incidental Mutation 'R1184:Tnrc6a'
| ID |
101923 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Tnrc6a
|
| Ensembl Gene |
ENSMUSG00000052707 |
| Gene Name |
trinucleotide repeat containing 6a |
| Synonyms |
3110054G10Rik, 2010321I05Rik, Tnrc6, CAGH26, D130023A07Rik |
| MMRRC Submission |
039256-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.879)
|
| Stock # |
R1184 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
7 |
| Chromosomal Location |
122723108-122794519 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 122769563 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Asparagine to Serine
at position 451
(N451S)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000091595
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000094053]
[ENSMUST00000205514]
[ENSMUST00000206014]
[ENSMUST00000206888]
|
| AlphaFold |
Q3UHK8 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000094053
AA Change: N451S
PolyPhen 2
Score 0.730 (Sensitivity: 0.86; Specificity: 0.92)
|
| SMART Domains |
Protein: ENSMUSP00000091595
Gene: ENSMUSG00000052707
AA Change: N451S
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
5 |
54 |
N/A |
INTRINSIC |
|
low complexity region
|
69 |
92 |
N/A |
INTRINSIC |
|
low complexity region
|
93 |
113 |
N/A |
INTRINSIC |
|
low complexity region
|
281 |
294 |
N/A |
INTRINSIC |
|
low complexity region
|
430 |
443 |
N/A |
INTRINSIC |
|
low complexity region
|
568 |
590 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
690 |
853 |
3.51e-6 |
PROSPERO |
|
low complexity region
|
858 |
871 |
N/A |
INTRINSIC |
|
Pfam:Ago_hook
|
1028 |
1190 |
1.2e-29 |
PFAM |
|
low complexity region
|
1284 |
1296 |
N/A |
INTRINSIC |
|
low complexity region
|
1301 |
1316 |
N/A |
INTRINSIC |
|
low complexity region
|
1337 |
1376 |
N/A |
INTRINSIC |
|
low complexity region
|
1386 |
1392 |
N/A |
INTRINSIC |
|
Pfam:TNRC6-PABC_bdg
|
1439 |
1714 |
1.5e-126 |
PFAM |
|
RRM
|
1717 |
1784 |
4.95e-2 |
SMART |
|
low complexity region
|
1808 |
1820 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000205449
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000205514
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000205732
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000205760
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000205789
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000206014
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000211170
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000206888
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000206922
|
| Meta Mutation Damage Score |
0.0746 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.2%
- 10x: 95.9%
- 20x: 91.5%
|
| Validation Efficiency |
100% (83/83) |
| MGI Phenotype |
FUNCTION: This gene encodes a member of the trinucleotide repeat containing 6 protein family. The protein is highly similar to a human protein that functions in post-transcriptional gene silencing through the RNA interference (RNAi) and microRNA pathways. The human protein associates with messenger RNAs and argonaute proteins in cytoplasmic bodies known as GW-bodies or P-bodies, and inhibiting its expression delocalizes other GW-body proteins and impairs RNAi and microRNA-induced gene silencing. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mice homozygous for a gene trap allele exhibit partial embryonic lethality during organogenesis associated with impaired hematopoiesis. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(21) : Gene trapped(21) |
| Other mutations in this stock |
Total: 82 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700003E16Rik |
A |
G |
6: 83,137,894 (GRCm39) |
R7G |
probably damaging |
Het |
| Ahdc1 |
T |
A |
4: 132,792,707 (GRCm39) |
M1316K |
probably benign |
Het |
| Alkal1 |
A |
G |
1: 6,459,712 (GRCm39) |
Y96C |
probably damaging |
Het |
| Anxa2r1 |
A |
T |
13: 120,496,667 (GRCm39) |
N67K |
probably benign |
Het |
| Arhgap17 |
T |
C |
7: 122,913,913 (GRCm39) |
Y199C |
probably damaging |
Het |
| Bmp2 |
T |
C |
2: 133,403,388 (GRCm39) |
V313A |
probably damaging |
Het |
| Cacna1b |
C |
T |
2: 24,577,757 (GRCm39) |
|
probably null |
Het |
| Cars1 |
T |
C |
7: 143,140,876 (GRCm39) |
T141A |
probably damaging |
Het |
| Ccdc57 |
A |
G |
11: 120,764,637 (GRCm39) |
|
probably benign |
Het |
| Cenpe |
T |
C |
3: 134,970,183 (GRCm39) |
|
probably null |
Het |
| Chadl |
T |
C |
15: 81,577,258 (GRCm39) |
S198G |
probably benign |
Het |
| Chd6 |
G |
C |
2: 160,872,722 (GRCm39) |
P286R |
probably damaging |
Het |
| Clec4a4 |
G |
T |
6: 122,989,671 (GRCm39) |
W104L |
probably benign |
Het |
| Coq4 |
G |
A |
2: 29,678,346 (GRCm39) |
|
probably benign |
Het |
| Cplane1 |
G |
T |
15: 8,245,971 (GRCm39) |
V1448L |
probably benign |
Het |
| Crtc2 |
T |
A |
3: 90,169,940 (GRCm39) |
Y445* |
probably null |
Het |
| Dapk1 |
A |
T |
13: 60,844,112 (GRCm39) |
I44F |
probably damaging |
Het |
| Dcbld2 |
T |
A |
16: 58,270,204 (GRCm39) |
|
probably null |
Het |
| Dcun1d4 |
T |
C |
5: 73,668,455 (GRCm39) |
|
probably benign |
Het |
| Depdc7 |
A |
T |
2: 104,560,523 (GRCm39) |
|
probably benign |
Het |
| Dna2 |
A |
G |
10: 62,794,977 (GRCm39) |
D416G |
probably benign |
Het |
| Dnah2 |
A |
T |
11: 69,390,016 (GRCm39) |
I743N |
probably damaging |
Het |
| Dnah9 |
A |
G |
11: 65,975,438 (GRCm39) |
|
probably null |
Het |
| Dock3 |
A |
G |
9: 106,846,999 (GRCm39) |
S877P |
probably damaging |
Het |
| Eif3l |
T |
A |
15: 78,959,966 (GRCm39) |
|
probably null |
Het |
| Epha5 |
A |
T |
5: 84,219,134 (GRCm39) |
|
probably null |
Het |
| Ffar3 |
T |
A |
7: 30,554,529 (GRCm39) |
N264Y |
probably damaging |
Het |
| Fyb1 |
A |
T |
15: 6,668,381 (GRCm39) |
I525F |
probably damaging |
Het |
| Fyco1 |
A |
G |
9: 123,648,218 (GRCm39) |
F1239L |
probably damaging |
Het |
| Gcdh |
T |
C |
8: 85,620,071 (GRCm39) |
|
probably benign |
Het |
| Gk5 |
T |
C |
9: 96,032,473 (GRCm39) |
|
probably benign |
Het |
| Grm1 |
A |
G |
10: 10,595,778 (GRCm39) |
Y617H |
probably benign |
Het |
| Gvin-ps3 |
A |
G |
7: 105,683,159 (GRCm39) |
V32A |
probably benign |
Het |
| Hhipl2 |
A |
T |
1: 183,206,042 (GRCm39) |
I131L |
probably damaging |
Het |
| Larp4b |
T |
C |
13: 9,216,345 (GRCm39) |
|
probably benign |
Het |
| Lrig2 |
T |
A |
3: 104,398,227 (GRCm39) |
I301F |
possibly damaging |
Het |
| Man2a2 |
A |
T |
7: 80,012,713 (GRCm39) |
I600N |
possibly damaging |
Het |
| Mylk2 |
G |
C |
2: 152,755,661 (GRCm39) |
|
probably null |
Het |
| Myo6 |
C |
T |
9: 80,193,664 (GRCm39) |
Q870* |
probably null |
Het |
| Napg |
T |
G |
18: 63,127,409 (GRCm39) |
H204Q |
probably benign |
Het |
| Neb |
G |
A |
2: 52,153,959 (GRCm39) |
T2384M |
probably damaging |
Het |
| Nek10 |
A |
G |
14: 14,931,325 (GRCm38) |
|
probably benign |
Het |
| Or11h23 |
A |
C |
14: 50,948,071 (GRCm39) |
T95P |
probably benign |
Het |
| Or4c111 |
A |
G |
2: 88,844,057 (GRCm39) |
M117T |
probably damaging |
Het |
| Or5an6 |
T |
C |
19: 12,372,221 (GRCm39) |
V198A |
probably benign |
Het |
| Or5b108 |
T |
G |
19: 13,168,739 (GRCm39) |
L236R |
probably damaging |
Het |
| Pclo |
A |
G |
5: 14,572,276 (GRCm39) |
T554A |
unknown |
Het |
| Perm1 |
C |
A |
4: 156,301,771 (GRCm39) |
T105K |
probably damaging |
Het |
| Pik3r1 |
T |
C |
13: 101,822,866 (GRCm39) |
|
probably null |
Het |
| Pld5 |
A |
G |
1: 175,872,462 (GRCm39) |
I225T |
probably damaging |
Het |
| Plxnc1 |
T |
C |
10: 94,667,195 (GRCm39) |
|
probably benign |
Het |
| Ptpn12 |
A |
C |
5: 21,203,354 (GRCm39) |
S475A |
possibly damaging |
Het |
| Ptprt |
A |
G |
2: 161,769,692 (GRCm39) |
V391A |
possibly damaging |
Het |
| Rac2 |
T |
G |
15: 78,450,145 (GRCm39) |
D65A |
possibly damaging |
Het |
| Rgl3 |
A |
G |
9: 21,888,676 (GRCm39) |
|
probably null |
Het |
| Rif1 |
GCCACCA |
GCCA |
2: 52,000,336 (GRCm39) |
|
probably benign |
Het |
| Sebox |
A |
T |
11: 78,394,675 (GRCm39) |
T47S |
probably damaging |
Het |
| Sema4b |
A |
G |
7: 79,874,388 (GRCm39) |
T593A |
probably benign |
Het |
| Serpina3a |
C |
T |
12: 104,082,787 (GRCm39) |
Q187* |
probably null |
Het |
| Serpinb1a |
T |
C |
13: 33,027,199 (GRCm39) |
K248E |
probably benign |
Het |
| Serpinb9e |
A |
C |
13: 33,443,757 (GRCm39) |
E259A |
probably benign |
Het |
| Slc30a3 |
T |
A |
5: 31,247,510 (GRCm39) |
H44L |
probably damaging |
Het |
| Smarca2 |
T |
C |
19: 26,748,333 (GRCm39) |
|
probably benign |
Het |
| Snrnp200 |
T |
A |
2: 127,078,737 (GRCm39) |
C1801S |
probably damaging |
Het |
| Soat1 |
G |
A |
1: 156,269,944 (GRCm39) |
|
probably null |
Het |
| Spink6 |
T |
C |
18: 44,204,605 (GRCm39) |
|
probably benign |
Het |
| Spta1 |
G |
A |
1: 174,012,256 (GRCm39) |
R354H |
probably damaging |
Het |
| Tbck |
T |
A |
3: 132,543,733 (GRCm39) |
H861Q |
probably benign |
Het |
| Tgfbrap1 |
G |
A |
1: 43,088,856 (GRCm39) |
T849M |
possibly damaging |
Het |
| Trim36 |
T |
C |
18: 46,329,318 (GRCm39) |
T41A |
probably damaging |
Het |
| Trmt112 |
C |
A |
19: 6,887,721 (GRCm39) |
|
probably benign |
Het |
| Trpc4ap |
A |
G |
2: 155,486,990 (GRCm39) |
|
probably benign |
Het |
| Ttll7 |
C |
T |
3: 146,645,746 (GRCm39) |
P535S |
probably damaging |
Het |
| Ttn |
A |
T |
2: 76,691,776 (GRCm39) |
|
probably benign |
Het |
| Txndc11 |
C |
T |
16: 10,946,364 (GRCm39) |
R149Q |
probably benign |
Het |
| Ubr4 |
C |
T |
4: 139,164,509 (GRCm39) |
|
probably benign |
Het |
| Usp30 |
G |
A |
5: 114,241,888 (GRCm39) |
|
probably null |
Het |
| Vmn1r195 |
A |
G |
13: 22,463,181 (GRCm39) |
Y217C |
probably damaging |
Het |
| Vps33b |
T |
A |
7: 79,932,234 (GRCm39) |
D135E |
probably benign |
Het |
| Vrk2 |
A |
G |
11: 26,433,331 (GRCm39) |
|
probably benign |
Het |
| Wdr81 |
G |
T |
11: 75,343,809 (GRCm39) |
P486Q |
probably damaging |
Het |
| Zfp788 |
T |
C |
7: 41,297,750 (GRCm39) |
Y129H |
probably damaging |
Het |
|
| Other mutations in Tnrc6a |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00335:Tnrc6a
|
APN |
7 |
122,770,003 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL00580:Tnrc6a
|
APN |
7 |
122,773,501 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01309:Tnrc6a
|
APN |
7 |
122,770,717 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL02004:Tnrc6a
|
APN |
7 |
122,780,589 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
IGL02142:Tnrc6a
|
APN |
7 |
122,751,414 (GRCm39) |
intron |
probably benign |
|
|
IGL02220:Tnrc6a
|
APN |
7 |
122,769,679 (GRCm39) |
missense |
probably benign |
|
|
IGL02436:Tnrc6a
|
APN |
7 |
122,783,438 (GRCm39) |
nonsense |
probably null |
|
|
IGL02670:Tnrc6a
|
APN |
7 |
122,770,535 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL02743:Tnrc6a
|
APN |
7 |
122,770,696 (GRCm39) |
missense |
probably damaging |
1.00 |
|
0152:Tnrc6a
|
UTSW |
7 |
122,779,877 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0008:Tnrc6a
|
UTSW |
7 |
122,769,617 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0008:Tnrc6a
|
UTSW |
7 |
122,769,617 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0369:Tnrc6a
|
UTSW |
7 |
122,770,083 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0512:Tnrc6a
|
UTSW |
7 |
122,785,951 (GRCm39) |
splice site |
probably benign |
|
|
R0566:Tnrc6a
|
UTSW |
7 |
122,770,136 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0600:Tnrc6a
|
UTSW |
7 |
122,771,039 (GRCm39) |
missense |
probably benign |
0.14 |
|
R0751:Tnrc6a
|
UTSW |
7 |
122,769,563 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R1319:Tnrc6a
|
UTSW |
7 |
122,783,474 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1405:Tnrc6a
|
UTSW |
7 |
122,770,301 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1405:Tnrc6a
|
UTSW |
7 |
122,770,301 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1585:Tnrc6a
|
UTSW |
7 |
122,776,098 (GRCm39) |
missense |
probably benign |
0.08 |
|
R1709:Tnrc6a
|
UTSW |
7 |
122,769,205 (GRCm39) |
missense |
probably benign |
0.10 |
|
R1776:Tnrc6a
|
UTSW |
7 |
122,770,520 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1791:Tnrc6a
|
UTSW |
7 |
122,792,140 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R1807:Tnrc6a
|
UTSW |
7 |
122,761,669 (GRCm39) |
splice site |
probably benign |
|
|
R1876:Tnrc6a
|
UTSW |
7 |
122,761,669 (GRCm39) |
splice site |
probably benign |
|
|
R2010:Tnrc6a
|
UTSW |
7 |
122,770,269 (GRCm39) |
missense |
probably benign |
0.26 |
|
R2086:Tnrc6a
|
UTSW |
7 |
122,761,669 (GRCm39) |
splice site |
probably benign |
|
|
R2089:Tnrc6a
|
UTSW |
7 |
122,771,343 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2091:Tnrc6a
|
UTSW |
7 |
122,771,343 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2091:Tnrc6a
|
UTSW |
7 |
122,771,343 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2511:Tnrc6a
|
UTSW |
7 |
122,770,315 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2830:Tnrc6a
|
UTSW |
7 |
122,792,172 (GRCm39) |
makesense |
probably null |
|
|
R2850:Tnrc6a
|
UTSW |
7 |
122,779,023 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3916:Tnrc6a
|
UTSW |
7 |
122,780,607 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4028:Tnrc6a
|
UTSW |
7 |
122,769,344 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4235:Tnrc6a
|
UTSW |
7 |
122,770,903 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4439:Tnrc6a
|
UTSW |
7 |
122,751,405 (GRCm39) |
nonsense |
probably null |
|
|
R4525:Tnrc6a
|
UTSW |
7 |
122,779,005 (GRCm39) |
missense |
probably benign |
|
|
R4578:Tnrc6a
|
UTSW |
7 |
122,783,444 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R4613:Tnrc6a
|
UTSW |
7 |
122,783,512 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4711:Tnrc6a
|
UTSW |
7 |
122,770,301 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4722:Tnrc6a
|
UTSW |
7 |
122,791,313 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R4746:Tnrc6a
|
UTSW |
7 |
122,789,220 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4892:Tnrc6a
|
UTSW |
7 |
122,769,134 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4942:Tnrc6a
|
UTSW |
7 |
122,791,836 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4967:Tnrc6a
|
UTSW |
7 |
122,789,095 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5064:Tnrc6a
|
UTSW |
7 |
122,785,946 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5239:Tnrc6a
|
UTSW |
7 |
122,785,842 (GRCm39) |
missense |
probably benign |
|
|
R5604:Tnrc6a
|
UTSW |
7 |
122,773,459 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5805:Tnrc6a
|
UTSW |
7 |
122,769,299 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5942:Tnrc6a
|
UTSW |
7 |
122,785,888 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5988:Tnrc6a
|
UTSW |
7 |
122,781,603 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6212:Tnrc6a
|
UTSW |
7 |
122,742,965 (GRCm39) |
splice site |
probably null |
|
|
R6284:Tnrc6a
|
UTSW |
7 |
122,770,558 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6417:Tnrc6a
|
UTSW |
7 |
122,770,297 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6420:Tnrc6a
|
UTSW |
7 |
122,770,297 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6575:Tnrc6a
|
UTSW |
7 |
122,769,133 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6760:Tnrc6a
|
UTSW |
7 |
122,771,222 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6886:Tnrc6a
|
UTSW |
7 |
122,786,668 (GRCm39) |
missense |
probably benign |
0.17 |
|
R6968:Tnrc6a
|
UTSW |
7 |
122,781,650 (GRCm39) |
missense |
probably benign |
0.05 |
|
R7216:Tnrc6a
|
UTSW |
7 |
122,770,718 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7260:Tnrc6a
|
UTSW |
7 |
122,785,813 (GRCm39) |
missense |
probably benign |
0.36 |
|
R7299:Tnrc6a
|
UTSW |
7 |
122,770,136 (GRCm39) |
missense |
probably benign |
|
|
R7322:Tnrc6a
|
UTSW |
7 |
122,770,731 (GRCm39) |
missense |
probably benign |
0.09 |
|
R7500:Tnrc6a
|
UTSW |
7 |
122,772,673 (GRCm39) |
splice site |
probably null |
|
|
R7872:Tnrc6a
|
UTSW |
7 |
122,779,057 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8270:Tnrc6a
|
UTSW |
7 |
122,769,294 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8313:Tnrc6a
|
UTSW |
7 |
122,769,936 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8348:Tnrc6a
|
UTSW |
7 |
122,791,346 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R8390:Tnrc6a
|
UTSW |
7 |
122,761,794 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8448:Tnrc6a
|
UTSW |
7 |
122,791,346 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R8514:Tnrc6a
|
UTSW |
7 |
122,783,438 (GRCm39) |
nonsense |
probably null |
|
|
R8552:Tnrc6a
|
UTSW |
7 |
122,761,669 (GRCm39) |
splice site |
probably benign |
|
|
R8767:Tnrc6a
|
UTSW |
7 |
122,783,133 (GRCm39) |
unclassified |
probably benign |
|
|
R9047:Tnrc6a
|
UTSW |
7 |
122,778,946 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9147:Tnrc6a
|
UTSW |
7 |
122,785,667 (GRCm39) |
intron |
probably benign |
|
|
R9153:Tnrc6a
|
UTSW |
7 |
122,773,519 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9166:Tnrc6a
|
UTSW |
7 |
122,786,624 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9179:Tnrc6a
|
UTSW |
7 |
122,791,881 (GRCm39) |
missense |
probably benign |
0.44 |
|
R9192:Tnrc6a
|
UTSW |
7 |
122,789,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9457:Tnrc6a
|
UTSW |
7 |
122,778,958 (GRCm39) |
missense |
probably benign |
0.24 |
|
R9778:Tnrc6a
|
UTSW |
7 |
122,769,635 (GRCm39) |
missense |
probably benign |
0.43 |
|
X0064:Tnrc6a
|
UTSW |
7 |
122,769,021 (GRCm39) |
missense |
probably benign |
0.28 |
|
Z1176:Tnrc6a
|
UTSW |
7 |
122,761,719 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- ACAATAGGATGAATGCTTGGGGCAC -3'
(R):5'- TAGGCACCCCATGTAGTACCGTAG -3'
Sequencing Primer
(F):5'- TTCAGTGTAGTACCATAGGCCAG -3'
(R):5'- ATGTAGTACCGTAGGAGCCTC -3'
|
| Posted On |
2014-01-15 |
Incidental Mutation