Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL00823:Dnah17'

10220

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Dnah17

Ensembl Gene

ENSMUSG00000033987

Gene Name

dynein, axonemal, heavy chain 17

Synonyms

Dnahcl1, LOC382552, 2810003K23Rik, Dnahc17

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

IGL00823

Quality Score

Status

Chromosome

Chromosomal Location

117912549-118021460 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

C to T at 117937987 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Valine to Isoleucine at position 3347 (V3347I)

Ref Sequence

ENSEMBL: ENSMUSP00000101915 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000084803] [ENSMUST00000106308] [ENSMUST00000132685]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000084803
AA Change: V3347I

PolyPhen 2 Score 0.123 (Sensitivity: 0.93; Specificity: 0.86)

SMART Domains

Protein: ENSMUSP00000081864
Gene: ENSMUSG00000033987
AA Change: V3347I

Domain	Start	End	E-Value	Type
Pfam:DHC_N1	183	766	8.5e-142	PFAM
low complexity region	1015	1028	N/A	INTRINSIC
Pfam:DHC_N2	1260	1673	5.8e-135	PFAM
Pfam:AAA_6	1793	2023	6e-161	PFAM
low complexity region	2092	2104	N/A	INTRINSIC
Pfam:AAA_5	2107	2243	7.8e-13	PFAM
Pfam:AAA_7	2400	2671	1.1e-171	PFAM
Pfam:AAA_8	2748	3015	4.9e-166	PFAM
Pfam:MT	3027	3370	3.4e-214	PFAM
Pfam:AAA_9	3388	3615	2.4e-144	PFAM
Pfam:Dynein_heavy	3742	4452	N/A	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000106308
AA Change: V3347I

PolyPhen 2 Score 0.221 (Sensitivity: 0.91; Specificity: 0.88)

SMART Domains

Protein: ENSMUSP00000101915
Gene: ENSMUSG00000033987
AA Change: V3347I

Domain	Start	End	E-Value	Type
Pfam:DHC_N1	184	764	1.7e-152	PFAM
low complexity region	1015	1028	N/A	INTRINSIC
Pfam:DHC_N2	1262	1671	4.1e-132	PFAM
Pfam:AAA_6	1793	2023	7e-149	PFAM
low complexity region	2092	2104	N/A	INTRINSIC
Pfam:AAA_5	2107	2243	2.5e-11	PFAM
Pfam:AAA_7	2400	2671	4.4e-169	PFAM
Pfam:AAA_8	2748	3015	7.1e-163	PFAM
Pfam:MT	3027	3370	1.1e-210	PFAM
Pfam:AAA_9	3392	3614	1e-84	PFAM
Pfam:Dynein_heavy	3748	4479	3.5e-230	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000132685
AA Change: V3360I

PolyPhen 2 Score 0.101 (Sensitivity: 0.93; Specificity: 0.86)

SMART Domains

Protein: ENSMUSP00000120542
Gene: ENSMUSG00000033987
AA Change: V3360I

Domain	Start	End	E-Value	Type
Pfam:DHC_N2	279	688	3.1e-132	PFAM
Pfam:AAA_6	811	1041	5.3e-149	PFAM
low complexity region	1110	1122	N/A	INTRINSIC
Blast:AAA	1123	1354	1e-104	BLAST
Pfam:AAA_7	1452	1671	8.9e-134	PFAM
Pfam:AAA_8	1763	2030	5.4e-163	PFAM
Pfam:MT	2042	2168	6.8e-52	PFAM
Pfam:MT	2163	2412	8.2e-149	PFAM
Pfam:AAA_9	2434	2656	7.9e-85	PFAM
Pfam:Dynein_heavy	2790	3457	2.6e-209	PFAM
Pfam:Dynein_heavy	3460	3569	4.6e-17	PFAM

Coding Region Coverage

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] Dyneins are microtubule-associated motor protein complexes composed of several heavy, light, and intermediate chains. DNAH17 is a heavy chain associated with axonemal dynein (Milisav and Affara, 1998 [PubMed 9545504]).[supplied by OMIM, Mar 2008]

Allele List at MGI

Other mutations in this stock

Total: 41 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Aasdh	T	C	5: 77,026,381 (GRCm39)		probably benign	Het
Adam5	T	C	8: 25,308,758 (GRCm39)	E39G	probably benign	Het
Anapc7	G	A	5: 122,571,540 (GRCm39)	W205*	probably null	Het
Arhgap5	C	T	12: 52,565,525 (GRCm39)	T832I	possibly damaging	Het
Arhgef10	T	A	8: 14,990,378 (GRCm39)		probably benign	Het
Atg5	A	G	10: 44,239,040 (GRCm39)	T274A	probably benign	Het
Baiap2l2	G	T	15: 79,168,765 (GRCm39)		probably benign	Het
Brap	T	A	5: 121,803,290 (GRCm39)	M146K	probably damaging	Het
Brpf1	T	C	6: 113,298,847 (GRCm39)	S1074P	probably benign	Het
Camta1	A	C	4: 151,169,058 (GRCm39)	I231R	probably benign	Het
Ccdc15	C	T	9: 37,231,709 (GRCm39)	G205D	probably benign	Het
Cd6	G	T	19: 10,773,758 (GRCm39)		probably benign	Het
Cdh17	T	G	4: 11,783,412 (GRCm39)	S219R	possibly damaging	Het
Cgn	G	A	3: 94,674,519 (GRCm39)	R873W	probably damaging	Het
Ctnna3	C	T	10: 63,373,322 (GRCm39)	P41L	possibly damaging	Het
Dmbt1	T	C	7: 130,659,888 (GRCm39)	W484R	probably benign	Het
Dmd	A	G	X: 83,469,419 (GRCm39)		probably null	Het
Fgd5	T	A	6: 91,965,440 (GRCm39)	S400T	possibly damaging	Het
Kitl	C	A	10: 99,923,206 (GRCm39)		probably benign	Het
Lamc3	A	T	2: 31,808,533 (GRCm39)	D763V	probably damaging	Het
Lgmn	T	C	12: 102,364,435 (GRCm39)		probably benign	Het
Lpcat2	T	G	8: 93,591,598 (GRCm39)	W81G	possibly damaging	Het
Myh13	A	G	11: 67,246,773 (GRCm39)	I1165V	probably benign	Het
Nf1	A	G	11: 79,456,343 (GRCm39)	D599G	probably damaging	Het
Nin	T	C	12: 70,061,567 (GRCm39)	N2099S	probably benign	Het
Nlrc4	T	C	17: 74,754,985 (GRCm39)	D77G	probably benign	Het
Otub1	A	G	19: 7,181,416 (GRCm39)		probably benign	Het
Pabir2	A	T	X: 52,334,208 (GRCm39)	C222S	probably damaging	Het
Pah	A	G	10: 87,406,193 (GRCm39)	Y174C	probably null	Het
Rbbp5	G	A	1: 132,417,444 (GRCm39)	V88I	probably damaging	Het
Scn1a	C	T	2: 66,155,279 (GRCm39)	R560H	probably benign	Het
Snx5	T	C	2: 144,097,485 (GRCm39)	I217V	probably benign	Het
Syne2	T	C	12: 76,036,016 (GRCm39)	S3769P	probably damaging	Het
Tent2	T	C	13: 93,322,905 (GRCm39)	T15A	probably benign	Het
Tmem255b	T	C	8: 13,507,054 (GRCm39)	M261T	probably benign	Het
Top3b	T	C	16: 16,705,486 (GRCm39)	I417T	probably damaging	Het
Tspan2	T	C	3: 102,665,549 (GRCm39)		probably null	Het
Ttn	T	C	2: 76,540,057 (GRCm39)	T34310A	possibly damaging	Het
Ush2a	G	A	1: 188,643,640 (GRCm39)	C4334Y	possibly damaging	Het
Wdpcp	A	G	11: 21,609,995 (GRCm39)	D21G	probably damaging	Het
Yy2	A	C	X: 156,351,207 (GRCm39)	D186E	probably benign	Het

Other mutations in Dnah17

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00231:Dnah17	APN	11	117,979,040 (GRCm39)	missense	possibly damaging	0.81
IGL00531:Dnah17	APN	11	117,933,999 (GRCm39)	missense	probably damaging	0.97
IGL00764:Dnah17	APN	11	117,987,311 (GRCm39)	missense	probably damaging	0.99
IGL00795:Dnah17	APN	11	117,984,460 (GRCm39)	missense	probably benign	0.35
IGL01145:Dnah17	APN	11	117,937,999 (GRCm39)	missense	possibly damaging	0.63
IGL01433:Dnah17	APN	11	117,940,760 (GRCm39)	missense	probably damaging	1.00
IGL01454:Dnah17	APN	11	117,949,223 (GRCm39)	missense	probably damaging	1.00
IGL01545:Dnah17	APN	11	118,010,394 (GRCm39)	missense	probably damaging	1.00
IGL01548:Dnah17	APN	11	117,989,438 (GRCm39)	missense	probably benign	0.21
IGL01557:Dnah17	APN	11	117,964,512 (GRCm39)	missense	probably damaging	0.98
IGL01632:Dnah17	APN	11	117,924,707 (GRCm39)	missense	probably damaging	1.00
IGL01636:Dnah17	APN	11	117,931,882 (GRCm39)	missense	probably benign	0.03
IGL01672:Dnah17	APN	11	117,932,986 (GRCm39)	missense	probably damaging	0.97
IGL01822:Dnah17	APN	11	117,972,819 (GRCm39)	missense	probably damaging	1.00
IGL01869:Dnah17	APN	11	117,943,502 (GRCm39)	missense	probably benign	0.09
IGL01916:Dnah17	APN	11	118,016,114 (GRCm39)	missense	probably benign	0.00
IGL02131:Dnah17	APN	11	117,963,734 (GRCm39)	missense	probably damaging	1.00
IGL02154:Dnah17	APN	11	118,015,087 (GRCm39)	missense	probably benign	0.01
IGL02220:Dnah17	APN	11	117,963,793 (GRCm39)	nonsense	probably null
IGL02454:Dnah17	APN	11	117,971,593 (GRCm39)	missense	probably damaging	0.98
IGL02458:Dnah17	APN	11	117,927,176 (GRCm39)	missense	probably damaging	1.00
IGL02588:Dnah17	APN	11	117,916,479 (GRCm39)	missense	possibly damaging	0.95
IGL02865:Dnah17	APN	11	117,964,374 (GRCm39)	missense	probably damaging	1.00
IGL02881:Dnah17	APN	11	117,932,944 (GRCm39)	missense	probably damaging	1.00
IGL02952:Dnah17	APN	11	117,979,094 (GRCm39)	missense	probably benign	0.03
IGL03382:Dnah17	APN	11	117,972,769 (GRCm39)	missense	probably damaging	1.00
IGL03389:Dnah17	APN	11	117,985,805 (GRCm39)	missense	probably damaging	1.00
ergos	UTSW	11	117,931,984 (GRCm39)	splice site	probably benign
watt	UTSW	11	117,971,592 (GRCm39)	missense	probably damaging	0.96
PIT4280001:Dnah17	UTSW	11	117,989,408 (GRCm39)	missense	possibly damaging	0.85
R0004:Dnah17	UTSW	11	117,950,918 (GRCm39)	missense	possibly damaging	0.90
R0112:Dnah17	UTSW	11	117,965,260 (GRCm39)	missense	possibly damaging	0.82
R0116:Dnah17	UTSW	11	117,949,132 (GRCm39)	missense	probably benign	0.01
R0157:Dnah17	UTSW	11	118,017,997 (GRCm39)	missense	probably benign
R0320:Dnah17	UTSW	11	117,943,500 (GRCm39)	missense	possibly damaging	0.56
R0362:Dnah17	UTSW	11	117,989,365 (GRCm39)	missense	probably benign	0.10
R0382:Dnah17	UTSW	11	118,019,822 (GRCm39)	missense	probably damaging	1.00
R0383:Dnah17	UTSW	11	117,958,373 (GRCm39)	missense	probably benign
R0400:Dnah17	UTSW	11	117,972,904 (GRCm39)	missense	probably damaging	1.00
R0420:Dnah17	UTSW	11	117,930,765 (GRCm39)	missense	probably damaging	1.00
R0483:Dnah17	UTSW	11	117,937,950 (GRCm39)	missense	probably benign
R0533:Dnah17	UTSW	11	118,001,363 (GRCm39)	missense	possibly damaging	0.50
R0562:Dnah17	UTSW	11	117,963,726 (GRCm39)	missense	probably damaging	1.00
R0564:Dnah17	UTSW	11	117,973,807 (GRCm39)	missense	probably damaging	1.00
R0604:Dnah17	UTSW	11	118,012,297 (GRCm39)	missense	probably benign	0.00
R0608:Dnah17	UTSW	11	117,981,575 (GRCm39)	nonsense	probably null
R0614:Dnah17	UTSW	11	117,961,394 (GRCm39)	splice site	probably benign
R0632:Dnah17	UTSW	11	117,958,508 (GRCm39)	splice site	probably benign
R0831:Dnah17	UTSW	11	117,951,097 (GRCm39)	missense	probably damaging	0.99
R0838:Dnah17	UTSW	11	117,950,930 (GRCm39)	missense	probably damaging	1.00
R0879:Dnah17	UTSW	11	117,947,661 (GRCm39)	splice site	probably benign
R1061:Dnah17	UTSW	11	117,943,514 (GRCm39)	missense	possibly damaging	0.51
R1190:Dnah17	UTSW	11	117,933,001 (GRCm39)	missense	probably damaging	1.00
R1293:Dnah17	UTSW	11	118,017,963 (GRCm39)	critical splice donor site	probably null
R1297:Dnah17	UTSW	11	118,012,192 (GRCm39)	splice site	probably benign
R1332:Dnah17	UTSW	11	117,934,041 (GRCm39)	missense	possibly damaging	0.70
R1336:Dnah17	UTSW	11	117,934,041 (GRCm39)	missense	possibly damaging	0.70
R1364:Dnah17	UTSW	11	118,016,432 (GRCm39)	splice site	probably benign
R1418:Dnah17	UTSW	11	117,964,849 (GRCm39)	missense	probably damaging	0.98
R1432:Dnah17	UTSW	11	117,914,153 (GRCm39)	missense	probably damaging	1.00
R1497:Dnah17	UTSW	11	118,005,059 (GRCm39)	missense	probably damaging	1.00
R1500:Dnah17	UTSW	11	117,991,879 (GRCm39)	missense	probably benign
R1506:Dnah17	UTSW	11	118,016,213 (GRCm39)	missense	possibly damaging	0.53
R1512:Dnah17	UTSW	11	117,985,841 (GRCm39)	missense	probably benign
R1567:Dnah17	UTSW	11	118,016,811 (GRCm39)	missense	probably damaging	1.00
R1597:Dnah17	UTSW	11	117,994,324 (GRCm39)	splice site	probably benign
R1665:Dnah17	UTSW	11	118,012,321 (GRCm39)	splice site	probably benign
R1703:Dnah17	UTSW	11	117,917,575 (GRCm39)	missense	probably damaging	1.00
R1716:Dnah17	UTSW	11	117,923,424 (GRCm39)	missense	probably benign	0.00
R1727:Dnah17	UTSW	11	117,987,362 (GRCm39)	nonsense	probably null
R1727:Dnah17	UTSW	11	117,961,315 (GRCm39)	missense	probably damaging	0.98
R1728:Dnah17	UTSW	11	117,960,345 (GRCm39)	missense	possibly damaging	0.76
R1784:Dnah17	UTSW	11	117,960,345 (GRCm39)	missense	possibly damaging	0.76
R1852:Dnah17	UTSW	11	118,012,742 (GRCm39)	missense	probably damaging	0.97
R1869:Dnah17	UTSW	11	117,938,015 (GRCm39)	nonsense	probably null
R1886:Dnah17	UTSW	11	117,998,987 (GRCm39)	missense	possibly damaging	0.62
R1893:Dnah17	UTSW	11	117,957,794 (GRCm39)	missense	probably benign	0.00
R1954:Dnah17	UTSW	11	117,915,557 (GRCm39)	missense	probably damaging	1.00
R1969:Dnah17	UTSW	11	117,995,361 (GRCm39)	missense	probably benign	0.00
R1971:Dnah17	UTSW	11	117,995,361 (GRCm39)	missense	probably benign	0.00
R1975:Dnah17	UTSW	11	117,987,362 (GRCm39)	nonsense	probably null
R1977:Dnah17	UTSW	11	118,003,417 (GRCm39)	missense	possibly damaging	0.52
R2055:Dnah17	UTSW	11	117,958,357 (GRCm39)	missense	probably benign	0.00
R2115:Dnah17	UTSW	11	118,010,628 (GRCm39)	missense	probably benign	0.00
R2132:Dnah17	UTSW	11	117,924,573 (GRCm39)	missense	probably damaging	0.98
R2200:Dnah17	UTSW	11	117,993,235 (GRCm39)	splice site	probably benign
R2277:Dnah17	UTSW	11	117,987,387 (GRCm39)	missense	possibly damaging	0.81
R2279:Dnah17	UTSW	11	117,987,387 (GRCm39)	missense	possibly damaging	0.81
R2400:Dnah17	UTSW	11	118,017,210 (GRCm39)	critical splice acceptor site	probably null
R2402:Dnah17	UTSW	11	118,016,800 (GRCm39)	missense	probably benign	0.10
R2497:Dnah17	UTSW	11	117,977,850 (GRCm39)	splice site	probably null
R2923:Dnah17	UTSW	11	117,984,373 (GRCm39)	missense	probably damaging	1.00
R3121:Dnah17	UTSW	11	117,931,912 (GRCm39)	missense	probably damaging	1.00
R3236:Dnah17	UTSW	11	117,985,680 (GRCm39)	missense	probably benign	0.08
R3237:Dnah17	UTSW	11	117,985,680 (GRCm39)	missense	probably benign	0.08
R3498:Dnah17	UTSW	11	117,971,675 (GRCm39)	splice site	probably benign
R3499:Dnah17	UTSW	11	117,971,675 (GRCm39)	splice site	probably benign
R3746:Dnah17	UTSW	11	117,973,742 (GRCm39)	missense	probably benign	0.00
R3749:Dnah17	UTSW	11	117,973,742 (GRCm39)	missense	probably benign	0.00
R3762:Dnah17	UTSW	11	117,995,352 (GRCm39)	missense	probably benign	0.00
R3826:Dnah17	UTSW	11	117,931,984 (GRCm39)	splice site	probably benign
R3828:Dnah17	UTSW	11	117,931,984 (GRCm39)	splice site	probably benign
R3829:Dnah17	UTSW	11	117,931,984 (GRCm39)	splice site	probably benign
R3877:Dnah17	UTSW	11	117,915,533 (GRCm39)	missense	probably damaging	1.00
R3899:Dnah17	UTSW	11	117,985,634 (GRCm39)	missense	possibly damaging	0.78
R3900:Dnah17	UTSW	11	117,985,634 (GRCm39)	missense	possibly damaging	0.78
R3911:Dnah17	UTSW	11	117,971,675 (GRCm39)	splice site	probably benign
R3913:Dnah17	UTSW	11	117,971,675 (GRCm39)	splice site	probably benign
R3930:Dnah17	UTSW	11	117,971,675 (GRCm39)	splice site	probably benign
R3931:Dnah17	UTSW	11	117,971,675 (GRCm39)	splice site	probably benign
R3969:Dnah17	UTSW	11	117,931,984 (GRCm39)	splice site	probably benign
R3970:Dnah17	UTSW	11	117,931,984 (GRCm39)	splice site	probably benign
R4056:Dnah17	UTSW	11	117,961,364 (GRCm39)	missense	probably benign	0.05
R4113:Dnah17	UTSW	11	118,003,420 (GRCm39)	missense	possibly damaging	0.50
R4295:Dnah17	UTSW	11	118,009,598 (GRCm39)	missense	probably damaging	1.00
R4324:Dnah17	UTSW	11	117,985,039 (GRCm39)	missense	probably benign	0.01
R4412:Dnah17	UTSW	11	117,964,509 (GRCm39)	missense	probably damaging	1.00
R4413:Dnah17	UTSW	11	117,915,994 (GRCm39)	missense	probably benign	0.00
R4422:Dnah17	UTSW	11	117,972,799 (GRCm39)	missense	possibly damaging	0.91
R4552:Dnah17	UTSW	11	117,943,769 (GRCm39)	missense	possibly damaging	0.79
R4669:Dnah17	UTSW	11	117,965,119 (GRCm39)	missense	probably benign	0.02
R4677:Dnah17	UTSW	11	118,010,640 (GRCm39)	missense	probably damaging	1.00
R4716:Dnah17	UTSW	11	117,964,474 (GRCm39)	missense	probably benign	0.02
R4832:Dnah17	UTSW	11	117,917,606 (GRCm39)	missense	probably damaging	1.00
R4868:Dnah17	UTSW	11	117,999,038 (GRCm39)	missense	probably benign	0.03
R4897:Dnah17	UTSW	11	117,969,419 (GRCm39)	missense	probably damaging	1.00
R4928:Dnah17	UTSW	11	117,918,259 (GRCm39)	missense	probably damaging	1.00
R4937:Dnah17	UTSW	11	117,932,980 (GRCm39)	missense	probably damaging	1.00
R4957:Dnah17	UTSW	11	117,965,124 (GRCm39)	missense	probably benign	0.44
R5008:Dnah17	UTSW	11	118,001,403 (GRCm39)	missense	probably benign	0.01
R5016:Dnah17	UTSW	11	117,971,592 (GRCm39)	missense	probably damaging	0.96
R5027:Dnah17	UTSW	11	117,993,365 (GRCm39)	missense	probably benign	0.01
R5133:Dnah17	UTSW	11	118,007,939 (GRCm39)	missense	probably benign	0.00
R5140:Dnah17	UTSW	11	117,977,771 (GRCm39)	missense	probably damaging	1.00
R5146:Dnah17	UTSW	11	118,005,005 (GRCm39)	missense	probably damaging	0.99
R5151:Dnah17	UTSW	11	117,918,293 (GRCm39)	missense	probably damaging	1.00
R5153:Dnah17	UTSW	11	117,973,800 (GRCm39)	nonsense	probably null
R5192:Dnah17	UTSW	11	117,925,185 (GRCm39)	missense	possibly damaging	0.96
R5315:Dnah17	UTSW	11	118,018,109 (GRCm39)	missense	possibly damaging	0.79
R5317:Dnah17	UTSW	11	118,018,109 (GRCm39)	missense	possibly damaging	0.79
R5335:Dnah17	UTSW	11	118,003,340 (GRCm39)	missense	probably damaging	1.00
R5379:Dnah17	UTSW	11	118,008,029 (GRCm39)	intron	probably benign
R5396:Dnah17	UTSW	11	118,018,108 (GRCm39)	missense	probably benign
R5418:Dnah17	UTSW	11	117,985,810 (GRCm39)	missense	probably benign	0.04
R5534:Dnah17	UTSW	11	117,943,596 (GRCm39)	missense	possibly damaging	0.83
R5539:Dnah17	UTSW	11	117,964,486 (GRCm39)	missense	probably benign	0.03
R5594:Dnah17	UTSW	11	117,934,055 (GRCm39)	splice site	probably null
R5634:Dnah17	UTSW	11	117,943,752 (GRCm39)	splice site	probably null
R5696:Dnah17	UTSW	11	117,991,882 (GRCm39)	missense	probably benign	0.44
R5802:Dnah17	UTSW	11	117,927,272 (GRCm39)	missense	possibly damaging	0.79
R5826:Dnah17	UTSW	11	117,925,193 (GRCm39)	missense	probably damaging	1.00
R5873:Dnah17	UTSW	11	117,947,723 (GRCm39)	missense	probably benign	0.01
R5898:Dnah17	UTSW	11	118,005,039 (GRCm39)	missense	probably benign	0.00
R5934:Dnah17	UTSW	11	117,931,928 (GRCm39)	missense	probably benign
R6030:Dnah17	UTSW	11	117,916,375 (GRCm39)	missense	probably benign	0.32
R6030:Dnah17	UTSW	11	117,916,375 (GRCm39)	missense	probably benign	0.32
R6038:Dnah17	UTSW	11	117,946,715 (GRCm39)	missense	probably benign	0.00
R6038:Dnah17	UTSW	11	117,946,715 (GRCm39)	missense	probably benign	0.00
R6113:Dnah17	UTSW	11	118,017,101 (GRCm39)	missense	probably damaging	1.00
R6117:Dnah17	UTSW	11	118,010,397 (GRCm39)	missense	probably benign	0.00
R6137:Dnah17	UTSW	11	117,916,480 (GRCm39)	missense	probably damaging	1.00
R6173:Dnah17	UTSW	11	117,930,772 (GRCm39)	missense	probably damaging	1.00
R6258:Dnah17	UTSW	11	118,017,149 (GRCm39)	nonsense	probably null
R6258:Dnah17	UTSW	11	118,017,148 (GRCm39)	missense	probably damaging	1.00
R6258:Dnah17	UTSW	11	118,017,150 (GRCm39)	missense	probably damaging	1.00
R6260:Dnah17	UTSW	11	118,017,150 (GRCm39)	missense	probably damaging	1.00
R6260:Dnah17	UTSW	11	118,017,148 (GRCm39)	missense	probably damaging	1.00
R6260:Dnah17	UTSW	11	118,017,149 (GRCm39)	nonsense	probably null
R6278:Dnah17	UTSW	11	118,017,116 (GRCm39)	missense	probably damaging	0.99
R6298:Dnah17	UTSW	11	117,998,987 (GRCm39)	missense	probably benign	0.00
R6300:Dnah17	UTSW	11	117,925,136 (GRCm39)	missense	probably damaging	1.00
R6302:Dnah17	UTSW	11	118,019,981 (GRCm39)	missense	probably benign	0.09
R6363:Dnah17	UTSW	11	118,001,331 (GRCm39)	missense	probably benign
R6381:Dnah17	UTSW	11	118,020,011 (GRCm39)	missense	probably benign	0.08
R6418:Dnah17	UTSW	11	118,020,023 (GRCm39)	missense	probably damaging	0.99
R6660:Dnah17	UTSW	11	117,991,014 (GRCm39)	missense	probably benign
R6803:Dnah17	UTSW	11	118,016,198 (GRCm39)	missense	probably benign	0.00
R6820:Dnah17	UTSW	11	117,959,826 (GRCm39)	missense	probably damaging	0.99
R6885:Dnah17	UTSW	11	117,981,598 (GRCm39)	missense	possibly damaging	0.47
R6921:Dnah17	UTSW	11	117,932,310 (GRCm39)	missense	probably damaging	0.98
R6932:Dnah17	UTSW	11	117,950,905 (GRCm39)	missense	possibly damaging	0.95
R6954:Dnah17	UTSW	11	117,957,258 (GRCm39)	missense	probably damaging	1.00
R7000:Dnah17	UTSW	11	117,916,528 (GRCm39)	critical splice acceptor site	probably null
R7007:Dnah17	UTSW	11	118,009,697 (GRCm39)	missense	possibly damaging	0.92
R7048:Dnah17	UTSW	11	117,936,944 (GRCm39)	missense	possibly damaging	0.80
R7056:Dnah17	UTSW	11	118,016,212 (GRCm39)	missense	probably benign
R7131:Dnah17	UTSW	11	117,970,484 (GRCm39)	missense	probably benign	0.14
R7143:Dnah17	UTSW	11	117,976,956 (GRCm39)	missense	probably damaging	1.00
R7146:Dnah17	UTSW	11	117,972,936 (GRCm39)	missense	probably damaging	0.98
R7147:Dnah17	UTSW	11	117,985,755 (GRCm39)	missense	probably benign	0.31
R7172:Dnah17	UTSW	11	117,931,957 (GRCm39)	nonsense	probably null
R7183:Dnah17	UTSW	11	118,020,014 (GRCm39)	missense	probably benign
R7297:Dnah17	UTSW	11	117,994,182 (GRCm39)	missense	probably damaging	0.98
R7297:Dnah17	UTSW	11	117,946,556 (GRCm39)	critical splice donor site	probably null
R7367:Dnah17	UTSW	11	118,006,022 (GRCm39)	missense	probably benign
R7398:Dnah17	UTSW	11	117,971,550 (GRCm39)	missense	probably damaging	0.96
R7426:Dnah17	UTSW	11	117,981,543 (GRCm39)	missense	probably null	0.79
R7524:Dnah17	UTSW	11	118,012,307 (GRCm39)	missense	probably benign	0.03
R7529:Dnah17	UTSW	11	117,940,692 (GRCm39)	critical splice donor site	probably null
R7615:Dnah17	UTSW	11	118,001,373 (GRCm39)	nonsense	probably null
R7681:Dnah17	UTSW	11	117,916,012 (GRCm39)	missense	probably damaging	1.00
R7702:Dnah17	UTSW	11	118,012,304 (GRCm39)	missense	possibly damaging	0.64
R7702:Dnah17	UTSW	11	117,916,466 (GRCm39)	missense	probably benign	0.00
R7713:Dnah17	UTSW	11	117,915,997 (GRCm39)	missense	probably benign	0.02
R7809:Dnah17	UTSW	11	117,995,462 (GRCm39)	missense	probably benign	0.09
R7842:Dnah17	UTSW	11	117,970,508 (GRCm39)	critical splice acceptor site	probably null
R7935:Dnah17	UTSW	11	118,018,048 (GRCm39)	missense	probably benign	0.20
R7951:Dnah17	UTSW	11	118,009,592 (GRCm39)	missense	possibly damaging	0.64
R8070:Dnah17	UTSW	11	117,915,497 (GRCm39)	missense	probably damaging	0.97
R8098:Dnah17	UTSW	11	117,941,193 (GRCm39)	missense	probably damaging	1.00
R8101:Dnah17	UTSW	11	118,016,744 (GRCm39)	missense	probably benign
R8177:Dnah17	UTSW	11	118,019,753 (GRCm39)	missense	possibly damaging	0.60
R8343:Dnah17	UTSW	11	118,005,021 (GRCm39)	missense	probably benign
R8350:Dnah17	UTSW	11	117,977,873 (GRCm39)	missense	probably damaging	0.98
R8393:Dnah17	UTSW	11	117,947,855 (GRCm39)	missense	probably damaging	1.00
R8401:Dnah17	UTSW	11	117,915,485 (GRCm39)	missense	probably damaging	0.96
R8418:Dnah17	UTSW	11	117,994,284 (GRCm39)	missense	probably benign	0.01
R8450:Dnah17	UTSW	11	117,977,873 (GRCm39)	missense	probably damaging	0.98
R8546:Dnah17	UTSW	11	118,015,101 (GRCm39)	missense	probably benign	0.00
R8697:Dnah17	UTSW	11	117,976,985 (GRCm39)	missense	possibly damaging	0.96
R8710:Dnah17	UTSW	11	117,932,973 (GRCm39)	missense	probably damaging	1.00
R8713:Dnah17	UTSW	11	117,979,028 (GRCm39)	missense	probably damaging	1.00
R8722:Dnah17	UTSW	11	117,961,283 (GRCm39)	nonsense	probably null
R8797:Dnah17	UTSW	11	117,992,201 (GRCm39)	missense	probably benign	0.00
R8953:Dnah17	UTSW	11	118,016,238 (GRCm39)	splice site	probably benign
R8965:Dnah17	UTSW	11	117,915,492 (GRCm39)	missense	probably damaging	1.00
R8976:Dnah17	UTSW	11	117,917,666 (GRCm39)	missense	probably damaging	1.00
R9090:Dnah17	UTSW	11	117,931,870 (GRCm39)	missense	probably damaging	1.00
R9128:Dnah17	UTSW	11	117,937,004 (GRCm39)	missense	possibly damaging	0.76
R9134:Dnah17	UTSW	11	117,978,972 (GRCm39)	missense	probably damaging	1.00
R9245:Dnah17	UTSW	11	118,016,503 (GRCm39)	missense	probably benign	0.02
R9251:Dnah17	UTSW	11	118,012,618 (GRCm39)	missense	probably benign	0.03
R9271:Dnah17	UTSW	11	117,931,870 (GRCm39)	missense	probably damaging	1.00
R9367:Dnah17	UTSW	11	118,012,212 (GRCm39)	missense	possibly damaging	0.93
R9367:Dnah17	UTSW	11	117,987,464 (GRCm39)	missense	possibly damaging	0.95
R9381:Dnah17	UTSW	11	117,914,219 (GRCm39)	missense	probably benign
R9405:Dnah17	UTSW	11	118,009,737 (GRCm39)	missense	probably benign
R9449:Dnah17	UTSW	11	117,987,452 (GRCm39)	missense	probably benign	0.07
R9517:Dnah17	UTSW	11	117,915,440 (GRCm39)	missense	possibly damaging	0.76
R9588:Dnah17	UTSW	11	118,012,783 (GRCm39)	missense	probably benign	0.00
R9629:Dnah17	UTSW	11	117,979,804 (GRCm39)	missense	probably damaging	1.00
R9654:Dnah17	UTSW	11	117,927,156 (GRCm39)	critical splice donor site	probably null
R9655:Dnah17	UTSW	11	117,971,649 (GRCm39)	missense	possibly damaging	0.94
R9662:Dnah17	UTSW	11	117,925,166 (GRCm39)	missense	probably damaging	0.97
R9686:Dnah17	UTSW	11	117,979,048 (GRCm39)	missense	possibly damaging	0.46
R9689:Dnah17	UTSW	11	117,963,731 (GRCm39)	missense	probably damaging	1.00
R9706:Dnah17	UTSW	11	118,017,026 (GRCm39)	missense	probably damaging	1.00
X0058:Dnah17	UTSW	11	117,973,751 (GRCm39)	missense	probably damaging	1.00
Z1176:Dnah17	UTSW	11	118,017,992 (GRCm39)	missense	probably benign	0.01
Z1177:Dnah17	UTSW	11	117,977,786 (GRCm39)	missense	probably damaging	1.00
Z1177:Dnah17	UTSW	11	117,969,389 (GRCm39)	missense	possibly damaging	0.91
Z1177:Dnah17	UTSW	11	118,017,968 (GRCm39)	nonsense	probably null

Posted On

2012-12-06