Incidental Mutation 'IGL01645:Gm5422'
ID102634
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Gm5422
Ensembl Gene ENSMUSG00000039684
Gene Namepredicted pseudogene 5422
Synonyms
Accession Numbers
Is this an essential gene? Probably essential (E-score: 0.793) question?
Stock #IGL01645
Quality Score
Status
Chromosome10
Chromosomal Location31248140-31251045 bp(+) (GRCm38)
Type of Mutationexon
DNA Base Change (assembly) A to T at 31250073 bp
ZygosityHeterozygous
Amino Acid Change
Gene Model predicted gene model for transcript(s):
Predicted Effect noncoding transcript
Transcript: ENSMUST00000050717
SMART Domains Protein: ENSMUSP00000135967
Gene: ENSMUSG00000039684

DomainStartEndE-ValueType
low complexity region 44 61 N/A INTRINSIC
Pfam:PC_rep 438 474 6.8e-9 PFAM
Pfam:PC_rep 475 509 1.1e-8 PFAM
SCOP:d1gw5a_ 603 760 4e-4 SMART
PDB:4CR4|Z 648 901 1e-50 PDB
Predicted Effect noncoding transcript
Transcript: ENSMUST00000216161
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 47 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
3632451O06Rik T C 14: 49,773,554 E232G probably damaging Het
Abcc8 C T 7: 46,115,053 C1156Y possibly damaging Het
Armc4 T C 18: 7,268,491 S343G probably benign Het
Atp8b1 G A 18: 64,546,113 H766Y probably benign Het
BC030867 T C 11: 102,255,186 L96P probably damaging Het
Cacna2d1 C A 5: 16,012,391 probably null Het
Card11 T A 5: 140,878,023 T987S probably benign Het
Dmxl2 A T 9: 54,378,733 Y2723N possibly damaging Het
Dnah11 T A 12: 118,186,998 I342F possibly damaging Het
Dnajc10 A G 2: 80,340,527 H454R possibly damaging Het
Dpy19l3 T C 7: 35,695,338 T592A probably benign Het
Eea1 T A 10: 95,989,589 S49T probably damaging Het
Esd T A 14: 74,749,719 N294K probably benign Het
Fmo3 A G 1: 162,964,006 V234A possibly damaging Het
Folh1 A G 7: 86,742,227 F420L probably damaging Het
Gabra1 T C 11: 42,135,562 N301S probably damaging Het
Gorab A T 1: 163,386,431 L310Q possibly damaging Het
Gsdme A G 6: 50,251,336 Y51H probably damaging Het
Itpr1 T C 6: 108,473,599 I1964T possibly damaging Het
Lmbr1 A G 5: 29,235,055 L410P probably damaging Het
Lrrc37a T C 11: 103,504,264 R112G probably benign Het
Mrgpra6 T C 7: 47,185,933 T247A probably benign Het
Mroh4 A G 15: 74,611,358 probably benign Het
Mycbpap T C 11: 94,503,467 probably null Het
Myoz2 T A 3: 123,034,232 K12N probably damaging Het
Olfr412 T C 11: 74,365,533 I288T possibly damaging Het
P3h1 T G 4: 119,236,783 F212V probably damaging Het
Pcnx2 T C 8: 125,887,917 D265G probably damaging Het
Pkd1l3 C T 8: 109,635,302 T992I possibly damaging Het
Prss58 T C 6: 40,897,310 D144G probably damaging Het
Pth2 T A 7: 45,181,340 L29Q possibly damaging Het
Rab1b A C 19: 5,104,934 probably benign Het
Rasa2 A T 9: 96,582,781 C190* probably null Het
Scn9a T C 2: 66,487,642 K1501E possibly damaging Het
Selenoi A G 5: 30,257,823 probably benign Het
Slc11a2 T C 15: 100,389,118 N558S probably benign Het
Sox10 T C 15: 79,156,339 I173V probably benign Het
Sra1 A C 18: 36,671,473 F476C probably damaging Het
St5 T A 7: 109,527,634 K540* probably null Het
Tmem119 T A 5: 113,795,348 K131* probably null Het
Trim12c T A 7: 104,345,054 K198* probably null Het
Ttn A G 2: 76,851,560 probably benign Het
Unc119b C T 5: 115,127,312 V154I probably benign Het
Usp47 T A 7: 112,054,862 S108R probably damaging Het
Vmn1r15 T A 6: 57,258,562 C138* probably null Het
Vmn1r191 T C 13: 22,179,444 I47V probably benign Het
Wnt3 C T 11: 103,812,378 A229V probably benign Het
Other mutations in Gm5422
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01306:Gm5422 APN 10 31249436 exon noncoding transcript
IGL01569:Gm5422 APN 10 31249901 exon noncoding transcript
IGL02273:Gm5422 APN 10 31250007 exon noncoding transcript
IGL02603:Gm5422 APN 10 31249440 exon noncoding transcript
IGL02928:Gm5422 APN 10 31250254 exon noncoding transcript
IGL03003:Gm5422 APN 10 31250844 exon noncoding transcript
IGL03274:Gm5422 APN 10 31250352 exon noncoding transcript
IGL03297:Gm5422 APN 10 31249731 exon noncoding transcript
ANU23:Gm5422 UTSW 10 31249436 exon noncoding transcript
R0010:Gm5422 UTSW 10 31249754 exon noncoding transcript
R0506:Gm5422 UTSW 10 31250322 exon noncoding transcript
R0560:Gm5422 UTSW 10 31249244 exon noncoding transcript
R0573:Gm5422 UTSW 10 31250160 exon noncoding transcript
R0652:Gm5422 UTSW 10 31249281 exon noncoding transcript
R1210:Gm5422 UTSW 10 31250723 intron noncoding transcript
R1259:Gm5422 UTSW 10 31249115 exon noncoding transcript
R1352:Gm5422 UTSW 10 31250735 intron noncoding transcript
R1631:Gm5422 UTSW 10 31249806 exon noncoding transcript
R1707:Gm5422 UTSW 10 31248462 exon noncoding transcript
R1893:Gm5422 UTSW 10 31249613 exon noncoding transcript
R2011:Gm5422 UTSW 10 31248768 exon noncoding transcript
R2132:Gm5422 UTSW 10 31248933 exon noncoding transcript
R3427:Gm5422 UTSW 10 31248846 exon noncoding transcript
R3772:Gm5422 UTSW 10 31248514 exon noncoding transcript
R4703:Gm5422 UTSW 10 31249612 exon noncoding transcript
R5539:Gm5422 UTSW 10 31248650 exon noncoding transcript
R5603:Gm5422 UTSW 10 31250844 exon noncoding transcript
R5660:Gm5422 UTSW 10 31250052 exon noncoding transcript
R6124:Gm5422 UTSW 10 31249400 exon noncoding transcript
R6178:Gm5422 UTSW 10 31249692 exon noncoding transcript
Posted On2014-01-21