Incidental Mutation 'IGL01650:Vmn1r62'
| ID |
102802 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Vmn1r62
|
| Ensembl Gene |
ENSMUSG00000092579 |
| Gene Name |
vomeronasal 1 receptor 62 |
| Synonyms |
V3R2, V1rd8, V1rd2 |
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.043)
|
| Stock # |
IGL01650
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
7 |
| Chromosomal Location |
5677603-5679598 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 5679024 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Alanine
at position 235
(V235A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000134168
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000173956]
|
| AlphaFold |
Q8R2C0 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000173956
AA Change: V235A
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000134168
Gene: ENSMUSG00000092579
AA Change: V235A
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:TAS2R
|
1 |
296 |
2.8e-11 |
PFAM |
|
Pfam:7tm_1
|
20 |
279 |
3.1e-6 |
PFAM |
|
Pfam:V1R
|
31 |
299 |
4.2e-18 |
PFAM |
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 34 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Agbl1 |
A |
G |
7: 76,070,067 (GRCm39) |
D281G |
probably damaging |
Het |
| Arhgap28 |
T |
C |
17: 68,180,127 (GRCm39) |
E236G |
probably damaging |
Het |
| Bltp1 |
G |
A |
3: 37,046,822 (GRCm39) |
|
probably benign |
Het |
| Btbd3 |
A |
T |
2: 138,126,025 (GRCm39) |
D334V |
probably damaging |
Het |
| Cabp4 |
T |
C |
19: 4,189,323 (GRCm39) |
E78G |
probably benign |
Het |
| Clcn4 |
T |
C |
7: 7,287,280 (GRCm39) |
|
probably benign |
Het |
| Col14a1 |
A |
G |
15: 55,270,089 (GRCm39) |
Y600C |
unknown |
Het |
| Cpne4 |
A |
G |
9: 104,778,710 (GRCm39) |
D167G |
probably damaging |
Het |
| Eif3a |
T |
A |
19: 60,762,434 (GRCm39) |
I450F |
probably damaging |
Het |
| Enpp2 |
T |
A |
15: 54,783,329 (GRCm39) |
Y10F |
probably benign |
Het |
| Fam227a |
A |
T |
15: 79,518,274 (GRCm39) |
H339Q |
possibly damaging |
Het |
| Far2 |
C |
A |
6: 148,074,985 (GRCm39) |
T406K |
possibly damaging |
Het |
| Fmo1 |
A |
G |
1: 162,661,153 (GRCm39) |
S377P |
probably benign |
Het |
| Fsip2 |
G |
A |
2: 82,821,430 (GRCm39) |
S5721N |
probably benign |
Het |
| Gatb |
T |
C |
3: 85,520,791 (GRCm39) |
I300T |
possibly damaging |
Het |
| Gpam |
T |
C |
19: 55,070,132 (GRCm39) |
N375D |
probably benign |
Het |
| Gsdma |
G |
T |
11: 98,564,513 (GRCm39) |
D331Y |
probably damaging |
Het |
| Kif13b |
T |
C |
14: 65,002,594 (GRCm39) |
V1073A |
probably benign |
Het |
| Mfsd4b1 |
T |
A |
10: 39,879,115 (GRCm39) |
M261L |
probably benign |
Het |
| Nav1 |
A |
T |
1: 135,382,498 (GRCm39) |
D1321E |
probably damaging |
Het |
| Or4f59 |
A |
G |
2: 111,872,720 (GRCm39) |
I219T |
possibly damaging |
Het |
| Or52j3 |
A |
G |
7: 102,836,286 (GRCm39) |
I159M |
probably benign |
Het |
| Or6c69 |
A |
G |
10: 129,747,550 (GRCm39) |
V199A |
probably benign |
Het |
| Or6c76b |
T |
A |
10: 129,692,936 (GRCm39) |
L183Q |
probably damaging |
Het |
| Or8g32 |
G |
T |
9: 39,305,252 (GRCm39) |
S55I |
probably damaging |
Het |
| Ppp1r10 |
G |
T |
17: 36,242,053 (GRCm39) |
R857L |
unknown |
Het |
| Prune2 |
T |
A |
19: 17,145,656 (GRCm39) |
I2752N |
possibly damaging |
Het |
| Pxdn |
T |
C |
12: 30,052,400 (GRCm39) |
I859T |
probably benign |
Het |
| Ros1 |
T |
C |
10: 52,031,075 (GRCm39) |
D510G |
probably damaging |
Het |
| Sema3g |
C |
A |
14: 30,943,744 (GRCm39) |
P208H |
probably benign |
Het |
| Smcr8 |
T |
C |
11: 60,669,010 (GRCm39) |
F53L |
probably damaging |
Het |
| Tnfsf13b |
A |
T |
8: 10,081,411 (GRCm39) |
I219F |
probably damaging |
Het |
| Vmn2r44 |
C |
A |
7: 8,383,103 (GRCm39) |
|
probably null |
Het |
| Zkscan7 |
A |
G |
9: 122,723,892 (GRCm39) |
D287G |
probably benign |
Het |
|
| Other mutations in Vmn1r62 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01337:Vmn1r62
|
APN |
7 |
5,679,144 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02892:Vmn1r62
|
APN |
7 |
5,679,202 (GRCm39) |
missense |
probably benign |
|
|
IGL02970:Vmn1r62
|
APN |
7 |
5,678,567 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
IGL03282:Vmn1r62
|
APN |
7 |
5,678,547 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R0470:Vmn1r62
|
UTSW |
7 |
5,679,066 (GRCm39) |
nonsense |
probably null |
|
|
R1416:Vmn1r62
|
UTSW |
7 |
5,678,904 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2149:Vmn1r62
|
UTSW |
7 |
5,678,358 (GRCm39) |
missense |
probably benign |
0.18 |
|
R4093:Vmn1r62
|
UTSW |
7 |
5,678,943 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4596:Vmn1r62
|
UTSW |
7 |
5,678,306 (GRCm39) |
start gained |
probably benign |
|
|
R4809:Vmn1r62
|
UTSW |
7 |
5,678,866 (GRCm39) |
missense |
probably benign |
0.41 |
|
R5669:Vmn1r62
|
UTSW |
7 |
5,678,736 (GRCm39) |
nonsense |
probably null |
|
|
R6262:Vmn1r62
|
UTSW |
7 |
5,678,556 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6312:Vmn1r62
|
UTSW |
7 |
5,679,083 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R6548:Vmn1r62
|
UTSW |
7 |
5,678,769 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7624:Vmn1r62
|
UTSW |
7 |
5,678,600 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7710:Vmn1r62
|
UTSW |
7 |
5,678,182 (GRCm39) |
start gained |
probably benign |
|
|
R7896:Vmn1r62
|
UTSW |
7 |
5,678,609 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8117:Vmn1r62
|
UTSW |
7 |
5,678,726 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R8673:Vmn1r62
|
UTSW |
7 |
5,678,277 (GRCm39) |
start gained |
probably benign |
|
|
R8714:Vmn1r62
|
UTSW |
7 |
5,678,629 (GRCm39) |
nonsense |
probably null |
|
|
R8962:Vmn1r62
|
UTSW |
7 |
5,678,601 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9133:Vmn1r62
|
UTSW |
7 |
5,679,062 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9246:Vmn1r62
|
UTSW |
7 |
5,678,628 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9360:Vmn1r62
|
UTSW |
7 |
5,678,952 (GRCm39) |
missense |
probably damaging |
0.99 |
|
RF007:Vmn1r62
|
UTSW |
7 |
5,678,669 (GRCm39) |
missense |
probably benign |
0.00 |
|
| Posted On |
2014-01-21 |
Incidental Mutation