Incidental Mutation 'IGL01680:Zfp647'
ID103782
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Zfp647
Ensembl Gene ENSMUSG00000054967
Gene Namezinc finger protein 647
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.132) question?
Stock #IGL01680
Quality Score
Status
Chromosome15
Chromosomal Location76910371-76925448 bp(-) (GRCm38)
Type of Mutationsplice site
DNA Base Change (assembly) T to A at 76917768 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000155660 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000048854] [ENSMUST00000229055] [ENSMUST00000229865] [ENSMUST00000230677]
Predicted Effect probably benign
Transcript: ENSMUST00000048854
SMART Domains Protein: ENSMUSP00000041575
Gene: ENSMUSG00000054967

DomainStartEndE-ValueType
low complexity region 2 15 N/A INTRINSIC
KRAB 17 77 7.05e-33 SMART
ZnF_C2H2 174 196 3.39e-3 SMART
ZnF_C2H2 202 224 1.2e-3 SMART
ZnF_C2H2 230 252 2.95e-3 SMART
ZnF_C2H2 258 280 4.79e-3 SMART
ZnF_C2H2 286 308 1.84e-4 SMART
ZnF_C2H2 314 336 6.32e-3 SMART
ZnF_C2H2 342 364 7.37e-4 SMART
ZnF_C2H2 370 392 1.6e-4 SMART
ZnF_C2H2 398 420 2.2e-2 SMART
ZnF_C2H2 426 448 6.78e-3 SMART
ZnF_C2H2 454 476 4.87e-4 SMART
ZnF_C2H2 482 504 2.24e-3 SMART
ZnF_C2H2 510 532 9.08e-4 SMART
Predicted Effect probably benign
Transcript: ENSMUST00000229055
Predicted Effect probably benign
Transcript: ENSMUST00000229865
Predicted Effect probably benign
Transcript: ENSMUST00000230677
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 37 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Adgre1 T C 17: 57,402,620 W121R unknown Het
Adprh C T 16: 38,450,216 G76S possibly damaging Het
Arhgap31 T C 16: 38,603,614 T697A probably benign Het
Ces2f T C 8: 104,954,073 M489T probably benign Het
Clec5a A G 6: 40,584,380 Y44H probably benign Het
Csmd3 T C 15: 47,970,030 H950R probably damaging Het
Dgkz G T 2: 91,935,865 P784T probably benign Het
Dok1 T C 6: 83,031,312 D463G possibly damaging Het
Eif4a2 C A 16: 23,109,191 Q94K probably benign Het
Epg5 T C 18: 78,012,741 L1710P probably damaging Het
Fam45a A G 19: 60,817,534 T86A possibly damaging Het
Fign A G 2: 63,978,644 probably benign Het
Gbp10 T C 5: 105,224,271 probably null Het
Gga2 G T 7: 121,998,076 D363E probably benign Het
Glis2 T A 16: 4,611,331 F133I possibly damaging Het
Isg20 A G 7: 78,916,585 D94G probably damaging Het
Kif23 T C 9: 61,931,814 D319G probably benign Het
Lbr C A 1: 181,836,194 R87L probably damaging Het
Map3k9 T C 12: 81,724,739 T715A probably benign Het
Mapk14 T C 17: 28,725,846 probably null Het
Mpp4 A C 1: 59,130,067 C341W probably benign Het
Mroh9 C T 1: 163,047,982 probably null Het
Myo16 T C 8: 10,272,630 V20A probably damaging Het
Olfr1120 T C 2: 87,357,905 S154P probably damaging Het
Olfr371 A T 8: 85,230,679 L61F probably benign Het
Olfr551 A T 7: 102,588,229 C171* probably null Het
Pofut2 C T 10: 77,263,293 R186W probably damaging Het
Ppp1r1b T A 11: 98,350,566 probably null Het
Slc34a2 A G 5: 53,060,876 I166V probably damaging Het
Slc4a2 A G 5: 24,432,930 T375A probably benign Het
Slitrk5 C A 14: 111,679,000 H19N probably benign Het
Sptb T A 12: 76,630,682 Q126L probably damaging Het
Stoml1 T C 9: 58,256,713 V105A probably damaging Het
Stt3b C A 9: 115,246,261 probably benign Het
Thbs4 T C 13: 92,776,980 E144G probably benign Het
Tns3 A G 11: 8,548,937 Y49H probably damaging Het
Vmn2r87 C T 10: 130,479,717 W160* probably null Het
Other mutations in Zfp647
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01565:Zfp647 APN 15 76911670 nonsense probably null
IGL02647:Zfp647 APN 15 76917715 missense probably damaging 1.00
IGL03213:Zfp647 APN 15 76911977 missense possibly damaging 0.46
IGL03401:Zfp647 APN 15 76911368 missense probably damaging 1.00
R0418:Zfp647 UTSW 15 76911386 missense probably damaging 1.00
R1479:Zfp647 UTSW 15 76911203 missense possibly damaging 0.94
R1913:Zfp647 UTSW 15 76911951 missense probably benign 0.02
R1959:Zfp647 UTSW 15 76911114 missense possibly damaging 0.57
R2176:Zfp647 UTSW 15 76911660 missense probably damaging 1.00
R3076:Zfp647 UTSW 15 76918009 start codon destroyed probably null
R3077:Zfp647 UTSW 15 76918009 start codon destroyed probably null
R3701:Zfp647 UTSW 15 76910910 missense probably damaging 1.00
R3702:Zfp647 UTSW 15 76910910 missense probably damaging 1.00
R3960:Zfp647 UTSW 15 76910976 unclassified probably null
R4938:Zfp647 UTSW 15 76911044 frame shift probably null
R4939:Zfp647 UTSW 15 76911044 frame shift probably null
R5196:Zfp647 UTSW 15 76912085 missense probably damaging 0.96
R5197:Zfp647 UTSW 15 76912085 missense probably damaging 0.96
R5345:Zfp647 UTSW 15 76911495 missense possibly damaging 0.48
R5415:Zfp647 UTSW 15 76911393 missense possibly damaging 0.79
R5791:Zfp647 UTSW 15 76918006 missense unknown
R5942:Zfp647 UTSW 15 76912085 missense probably damaging 0.96
R5944:Zfp647 UTSW 15 76912085 missense probably damaging 0.96
R5945:Zfp647 UTSW 15 76912085 missense probably damaging 0.96
R5946:Zfp647 UTSW 15 76912085 missense probably damaging 0.96
R5947:Zfp647 UTSW 15 76912085 missense probably damaging 0.96
R6005:Zfp647 UTSW 15 76912085 missense probably damaging 0.96
R6007:Zfp647 UTSW 15 76912085 missense probably damaging 0.96
R6073:Zfp647 UTSW 15 76912085 missense probably damaging 0.96
R6074:Zfp647 UTSW 15 76912085 missense probably damaging 0.96
R6101:Zfp647 UTSW 15 76912085 missense probably damaging 0.96
R6102:Zfp647 UTSW 15 76912085 missense probably damaging 0.96
R6103:Zfp647 UTSW 15 76912085 missense probably damaging 0.96
R6126:Zfp647 UTSW 15 76912085 missense probably damaging 0.96
R6127:Zfp647 UTSW 15 76912085 missense probably damaging 0.96
R6129:Zfp647 UTSW 15 76912085 missense probably damaging 0.96
R6136:Zfp647 UTSW 15 76912085 missense probably damaging 0.96
R6151:Zfp647 UTSW 15 76912085 missense probably damaging 0.96
R6305:Zfp647 UTSW 15 76912085 missense probably damaging 0.96
R6306:Zfp647 UTSW 15 76912085 missense probably damaging 0.96
R6329:Zfp647 UTSW 15 76912085 missense probably damaging 0.96
R6721:Zfp647 UTSW 15 76911876 missense probably benign 0.00
R7158:Zfp647 UTSW 15 76917305 missense probably benign 0.01
R7239:Zfp647 UTSW 15 76911756 missense probably damaging 1.00
Posted On2014-01-21