Incidental Mutation 'IGL01689:Lypd5'
| ID |
104060 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Lypd5
|
| Ensembl Gene |
ENSMUSG00000030484 |
| Gene Name |
Ly6/Plaur domain containing 5 |
| Synonyms |
2210003I03Rik, 2310011E23Rik |
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
IGL01689
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
7 |
| Chromosomal Location |
24048621-24053672 bp(+) (GRCm39) |
| Type of Mutation |
splice site |
| DNA Base Change (assembly) |
A to G
at 24052054 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000032683
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000032683]
|
| AlphaFold |
Q9D7Z7 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000032683
|
| SMART Domains |
Protein: ENSMUSP00000032683
Gene: ENSMUSG00000030484
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
23 |
N/A |
INTRINSIC |
|
Blast:LU
|
24 |
119 |
7e-38 |
BLAST |
|
LU
|
132 |
225 |
1.19e-1 |
SMART |
|
low complexity region
|
230 |
248 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 18 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Aox4 |
A |
G |
1: 58,284,320 (GRCm39) |
|
probably benign |
Het |
| Arhgap10 |
A |
G |
8: 78,137,763 (GRCm39) |
|
probably benign |
Het |
| Armc9 |
T |
C |
1: 86,202,140 (GRCm39) |
V766A |
probably benign |
Het |
| Asxl2 |
A |
T |
12: 3,546,425 (GRCm39) |
Q403L |
probably benign |
Het |
| Cd244a |
G |
A |
1: 171,410,462 (GRCm39) |
|
probably benign |
Het |
| Cdc34b |
A |
G |
11: 94,633,345 (GRCm39) |
K182E |
probably benign |
Het |
| Csnk1d |
A |
T |
11: 120,862,393 (GRCm39) |
F295L |
probably benign |
Het |
| Gm11541 |
A |
G |
11: 94,595,020 (GRCm39) |
V16A |
unknown |
Het |
| Kdr |
T |
C |
5: 76,097,500 (GRCm39) |
D1252G |
probably benign |
Het |
| Kif14 |
A |
G |
1: 136,447,380 (GRCm39) |
D1395G |
probably damaging |
Het |
| Lars1 |
T |
A |
18: 42,350,014 (GRCm39) |
Q930L |
probably benign |
Het |
| Or2w1b |
G |
A |
13: 21,300,243 (GRCm39) |
C127Y |
probably damaging |
Het |
| Paics |
T |
C |
5: 77,109,138 (GRCm39) |
|
probably null |
Het |
| Pcnt |
A |
G |
10: 76,247,487 (GRCm39) |
V1015A |
probably damaging |
Het |
| Thada |
C |
T |
17: 84,754,116 (GRCm39) |
S285N |
possibly damaging |
Het |
| Tlr1 |
T |
C |
5: 65,083,122 (GRCm39) |
D485G |
probably damaging |
Het |
| Vmn2r66 |
T |
C |
7: 84,657,033 (GRCm39) |
N124S |
probably damaging |
Het |
| Zfyve26 |
T |
C |
12: 79,330,827 (GRCm39) |
D464G |
possibly damaging |
Het |
|
| Other mutations in Lypd5 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01066:Lypd5
|
APN |
7 |
24,052,910 (GRCm39) |
missense |
probably benign |
0.10 |
|
IGL01121:Lypd5
|
APN |
7 |
24,050,976 (GRCm39) |
missense |
probably benign |
|
|
IGL02584:Lypd5
|
APN |
7 |
24,052,993 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
IGL02888:Lypd5
|
APN |
7 |
24,052,044 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5167:Lypd5
|
UTSW |
7 |
24,051,889 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R5982:Lypd5
|
UTSW |
7 |
24,052,462 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6746:Lypd5
|
UTSW |
7 |
24,052,531 (GRCm39) |
splice site |
probably null |
|
|
R7951:Lypd5
|
UTSW |
7 |
24,051,060 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8704:Lypd5
|
UTSW |
7 |
24,050,982 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R8725:Lypd5
|
UTSW |
7 |
24,053,101 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8727:Lypd5
|
UTSW |
7 |
24,053,101 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8897:Lypd5
|
UTSW |
7 |
24,051,015 (GRCm39) |
missense |
probably benign |
0.13 |
|
X0057:Lypd5
|
UTSW |
7 |
24,048,646 (GRCm39) |
utr 5 prime |
probably benign |
|
|
Z1177:Lypd5
|
UTSW |
7 |
24,052,038 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Posted On |
2014-01-21 |
Incidental Mutation