Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01690:Cfap107'

104070

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Cfap107

Ensembl Gene

ENSMUSG00000028589

Gene Name

cilia and flagella associated protein 107

Synonyms

1700012P22Rik

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.057) question?

Stock #

IGL01690

Quality Score

Status

Chromosome

Chromosomal Location

144144759-144165342 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

G to A at 144165098 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Threonine to Methionine at position 26 (T26M)

Ref Sequence

ENSEMBL: ENSMUSP00000030323 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000030323]

AlphaFold

no structure available at present

Predicted Effect

probably damaging
Transcript: ENSMUST00000030323
AA Change: T26M

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 38 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4931429P17Rik	A	G	13: 48,114,446 (GRCm39)		noncoding transcript	Het
Agap2	T	C	10: 126,918,827 (GRCm39)		probably benign	Het
Bicra	G	A	7: 15,721,678 (GRCm39)	T613I	probably benign	Het
Cd163	T	C	6: 124,284,277 (GRCm39)	S150P	possibly damaging	Het
F830045P16Rik	T	G	2: 129,314,614 (GRCm39)	Q221P	probably damaging	Het
Fam135b	T	A	15: 71,328,784 (GRCm39)	M1172L	probably benign	Het
Fbxo2	G	T	4: 148,249,581 (GRCm39)		probably null	Het
Frem1	C	T	4: 82,877,533 (GRCm39)		probably benign	Het
Galnt17	C	T	5: 131,114,734 (GRCm39)		probably null	Het
Gipc2	A	G	3: 151,833,771 (GRCm39)	I170T	probably damaging	Het
Gm2399	C	T	13: 12,717,417 (GRCm39)		noncoding transcript	Het
Hdac10	T	A	15: 89,010,194 (GRCm39)	M283L	probably benign	Het
Icam5	A	G	9: 20,946,095 (GRCm39)	E309G	possibly damaging	Het
Ift70a1	A	G	2: 75,810,277 (GRCm39)	V602A	probably benign	Het
Igkv3-5	T	A	6: 70,640,865 (GRCm39)	S115R	probably benign	Het
Impg2	A	G	16: 56,025,568 (GRCm39)	R67G	probably damaging	Het
Kansl1l	T	C	1: 66,840,232 (GRCm39)	Y356C	probably damaging	Het
Ly75	T	C	2: 60,168,655 (GRCm39)	D751G	probably damaging	Het
Lyst	A	G	13: 13,917,831 (GRCm39)	D3297G	probably damaging	Het
Mall	A	G	2: 127,571,699 (GRCm39)	F30L	probably benign	Het
Map1b	C	T	13: 99,571,512 (GRCm39)	G403D	probably damaging	Het
Mmp11	T	C	10: 75,762,730 (GRCm39)	Y241C	probably damaging	Het
Niban1	C	A	1: 151,579,555 (GRCm39)	R425S	probably damaging	Het
Or4a72	A	G	2: 89,405,557 (GRCm39)	V171A	probably benign	Het
Pcnt	C	T	10: 76,228,609 (GRCm39)	A1519T	probably damaging	Het
Pcsk2	A	G	2: 143,529,490 (GRCm39)	M96V	probably benign	Het
Piwil4	T	C	9: 14,614,391 (GRCm39)	D124G	probably damaging	Het
Plb1	A	T	5: 32,471,041 (GRCm39)	I538F	probably damaging	Het
Polq	A	G	16: 36,883,200 (GRCm39)	D1788G	probably damaging	Het
Pus7	A	G	5: 23,980,962 (GRCm39)	S134P	probably damaging	Het
Sec61a2	G	A	2: 5,891,363 (GRCm39)	S56L	possibly damaging	Het
Sel1l	G	T	12: 91,810,033 (GRCm39)	D26E	probably benign	Het
Slc25a48	G	A	13: 56,612,758 (GRCm39)		probably benign	Het
Tas2r126	T	C	6: 42,412,241 (GRCm39)	F258S	probably benign	Het
Tnfrsf13b	G	A	11: 61,032,146 (GRCm39)	V59I	possibly damaging	Het
Usp6nl	G	A	2: 6,445,879 (GRCm39)	V619M	probably benign	Het
Vmn1r67	A	G	7: 10,180,767 (GRCm39)	I10M	possibly damaging	Het
Vmn2r71	A	G	7: 85,264,782 (GRCm39)	D38G	probably damaging	Het

Other mutations in Cfap107

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL02120:Cfap107	APN	4	144,144,981 (GRCm39)	missense	probably benign	0.00
IGL03406:Cfap107	APN	4	144,150,414 (GRCm39)	missense	probably damaging	1.00
R0699:Cfap107	UTSW	4	144,146,322 (GRCm39)	missense	probably damaging	1.00
R5380:Cfap107	UTSW	4	144,150,372 (GRCm39)	missense	probably damaging	0.98
R7405:Cfap107	UTSW	4	144,146,323 (GRCm39)	missense	probably damaging	0.98
R7607:Cfap107	UTSW	4	144,146,332 (GRCm39)	missense	probably damaging	0.99

Posted On

2014-01-21