Incidental Mutation 'IGL01695:Gm6408'
ID104262
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Gm6408
Ensembl Gene ENSMUSG00000096344
Gene Namepredicted gene 6408
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.072) question?
Stock #IGL01695
Quality Score
Status
Chromosome5
Chromosomal Location146481965-146484704 bp(+) (GRCm38)
Type of Mutationsplice site
DNA Base Change (assembly) A to G at 146482129 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000136735 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000179032]
Predicted Effect probably benign
Transcript: ENSMUST00000179032
SMART Domains Protein: ENSMUSP00000136735
Gene: ENSMUSG00000096344

DomainStartEndE-ValueType
RasGEFN 66 182 4.47e-3 SMART
low complexity region 270 292 N/A INTRINSIC
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 36 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
2610507B11Rik T C 11: 78,265,193 V177A probably benign Het
Ap3b2 T A 7: 81,476,939 probably benign Het
Arfgef3 T C 10: 18,603,419 T1483A probably benign Het
Arl5a A T 2: 52,412,105 I99N probably damaging Het
Bahcc1 G A 11: 120,276,609 G1279R probably benign Het
Bbs5 A G 2: 69,649,090 N43S probably damaging Het
Cdh23 C T 10: 60,331,833 V1795M probably benign Het
Cep350 T C 1: 155,944,158 E353G probably damaging Het
Cps1 A T 1: 67,197,035 I976L probably benign Het
Ctdp1 A T 18: 80,449,626 S551R probably damaging Het
Cyp2b19 C T 7: 26,759,064 T68I probably damaging Het
Esr2 A G 12: 76,145,319 S312P probably damaging Het
Fam26e A G 10: 34,092,202 V285A possibly damaging Het
Gm11639 A T 11: 104,736,063 E864D probably damaging Het
Krt9 A T 11: 100,191,437 probably null Het
Myh6 T C 14: 54,957,413 T662A probably benign Het
Ntn1 T C 11: 68,226,604 D473G probably benign Het
Olfr576 T C 7: 102,965,583 F161S probably damaging Het
Piezo1 A T 8: 122,495,509 C961S possibly damaging Het
Pik3c2a T C 7: 116,417,518 T335A possibly damaging Het
Plaa A T 4: 94,574,037 Y140* probably null Het
Plxnb2 T C 15: 89,157,214 I1749V possibly damaging Het
Ppp1r9a T A 6: 5,064,003 N555K probably damaging Het
Ptprn2 T A 12: 116,841,388 H174Q probably benign Het
Reln G A 5: 21,920,438 T2749M probably damaging Het
Scarf1 A G 11: 75,521,957 N384S probably damaging Het
Scrt1 T A 15: 76,518,950 H280L unknown Het
Serpina1f C A 12: 103,693,684 C113F probably damaging Het
Setdb2 A T 14: 59,402,293 probably benign Het
Strc A G 2: 121,375,298 L830P probably damaging Het
Tifab T C 13: 56,176,385 S82G probably benign Het
Tmem217 T A 17: 29,526,348 H136L probably damaging Het
Trio T C 15: 27,773,001 E715G probably damaging Het
Ttn A T 2: 76,944,016 M2182K probably damaging Het
Ube2d1 T C 10: 71,262,252 D12G probably damaging Het
Utrn T C 10: 12,745,342 D195G probably benign Het
Other mutations in Gm6408
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01806:Gm6408 APN 5 146482082 missense probably damaging 1.00
R0211:Gm6408 UTSW 5 146483060 missense probably benign 0.04
R1763:Gm6408 UTSW 5 146482322 missense probably damaging 1.00
R3745:Gm6408 UTSW 5 146484436 missense probably damaging 1.00
R4393:Gm6408 UTSW 5 146482337 missense probably damaging 1.00
R5586:Gm6408 UTSW 5 146484457 missense possibly damaging 0.71
R5734:Gm6408 UTSW 5 146482382 missense probably benign 0.07
R5999:Gm6408 UTSW 5 146484257 missense possibly damaging 0.86
R6181:Gm6408 UTSW 5 146483772 missense possibly damaging 0.84
R7007:Gm6408 UTSW 5 146483837 missense probably damaging 1.00
R7063:Gm6408 UTSW 5 146483784 missense probably benign 0.01
R7224:Gm6408 UTSW 5 146484370 missense probably benign 0.10
Posted On2014-01-21