Incidental Mutation 'IGL00088:Ncbp3'
ID1162
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Ncbp3
Ensembl Gene ENSMUSG00000020783
Gene Namenuclear cap binding subunit 3
Synonyms1200014J11Rik
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.111) question?
Stock #IGL00088
Quality Score
Status
Chromosome11
Chromosomal Location73047783-73089317 bp(+) (GRCm38)
Type of Mutationsplice site
DNA Base Change (assembly) A to T at 73073529 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000021135 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000021135]
Predicted Effect probably benign
Transcript: ENSMUST00000021135
SMART Domains Protein: ENSMUSP00000021135
Gene: ENSMUSG00000020783

DomainStartEndE-ValueType
low complexity region 13 27 N/A INTRINSIC
low complexity region 33 52 N/A INTRINSIC
Pfam:DUF2414 123 177 4.5e-24 PFAM
low complexity region 191 231 N/A INTRINSIC
coiled coil region 345 364 N/A INTRINSIC
low complexity region 379 403 N/A INTRINSIC
low complexity region 581 592 N/A INTRINSIC
low complexity region 602 615 N/A INTRINSIC
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 63 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
4930572O03Rik C A 5: 15,656,886 probably benign Het
Ankhd1 A G 18: 36,665,459 probably benign Het
Anpep A G 7: 79,825,736 V879A possibly damaging Het
Asb13 T G 13: 3,643,476 V78G probably null Het
Atad2b A G 12: 5,024,593 R1051G probably damaging Het
Bdp1 T C 13: 100,098,510 Y192C probably damaging Het
C1ql2 G T 1: 120,341,670 G185C probably damaging Het
C87499 T A 4: 88,629,070 K121N probably benign Het
Catsperg2 A G 7: 29,705,404 S745P possibly damaging Het
Col19a1 A T 1: 24,561,306 S52T unknown Het
Col4a2 G T 8: 11,443,685 G1418V probably damaging Het
Crnkl1 C T 2: 145,918,468 D677N possibly damaging Het
Cyp2j8 T A 4: 96,503,842 N125I probably benign Het
Cyp2t4 A T 7: 27,155,298 M68L probably benign Het
Dclk2 T A 3: 86,799,090 probably null Het
Dmxl2 T C 9: 54,401,704 D1921G probably benign Het
Dnah10 G A 5: 124,828,603 G4104S probably damaging Het
Echdc2 T C 4: 108,178,911 I273T probably damaging Het
Extl1 T C 4: 134,358,019 K596E probably damaging Het
Fads3 A T 19: 10,052,299 D108V probably null Het
Fam135b A G 15: 71,450,494 L1274P probably damaging Het
Fat1 T A 8: 45,024,602 H2228Q possibly damaging Het
Gcc2 C T 10: 58,292,680 H1341Y probably damaging Het
Gls2 A G 10: 128,200,971 probably null Het
Gm13119 T A 4: 144,362,530 H139Q possibly damaging Het
Gpr137 A C 19: 6,939,704 V139G probably damaging Het
Ikbke A G 1: 131,270,012 probably null Het
Irak2 A T 6: 113,678,675 N285Y probably benign Het
Kcnu1 G A 8: 25,897,856 C566Y probably benign Het
Klhl29 G A 12: 5,140,705 P97S probably benign Het
Lama4 T C 10: 39,065,595 probably benign Het
Lhx6 G A 2: 36,091,716 probably benign Het
Mdn1 T C 4: 32,723,651 L2529P probably damaging Het
Muc4 G A 16: 32,754,086 G1321R probably benign Het
Naa15 T A 3: 51,438,405 V19D probably damaging Het
Nckipsd G A 9: 108,814,969 V530I probably benign Het
Neb A G 2: 52,308,747 I394T possibly damaging Het
Nnmt A T 9: 48,591,924 probably benign Het
Nupl1 T A 14: 60,242,577 I207L probably benign Het
Olfr113 A T 17: 37,574,917 C169S probably damaging Het
Olfr180 C T 16: 58,915,850 E264K probably benign Het
Olfr290 T A 7: 84,916,370 M197K probably damaging Het
Otud4 T A 8: 79,672,881 N741K probably damaging Het
Pard6a T A 8: 105,703,201 C264S probably benign Het
Plch2 T C 4: 155,006,642 N276S probably damaging Het
Racgap1 T C 15: 99,636,122 probably benign Het
Rad51d T C 11: 82,889,746 D70G probably damaging Het
Recql4 C T 15: 76,707,336 A484T possibly damaging Het
Reg3g A T 6: 78,466,779 S149T probably benign Het
Rpl13a C A 7: 45,127,071 probably null Het
Scn10a T C 9: 119,672,226 Y164C probably damaging Het
Scn2a A G 2: 65,764,440 I1878V probably benign Het
Sgcg T A 14: 61,240,347 R98* probably null Het
Tas2r137 A T 6: 40,491,340 I35F probably benign Het
Tex19.2 A G 11: 121,116,812 F270S possibly damaging Het
Traip C T 9: 107,970,550 R391W probably benign Het
Trim7 A G 11: 48,845,571 N251D probably damaging Het
Trmt2a T A 16: 18,249,487 V8D probably benign Het
Ubr3 A C 2: 69,988,810 I9L probably benign Het
Usp42 A G 5: 143,717,142 S575P probably benign Het
Vmn2r52 G T 7: 10,169,096 H468Q probably benign Het
Vmn2r59 T A 7: 42,012,064 T776S possibly damaging Het
Zcchc6 T C 13: 59,816,698 E221G probably damaging Het
Other mutations in Ncbp3
AlleleSourceChrCoordTypePredicted EffectPPH Score
R0180:Ncbp3 UTSW 11 73064978 splice site probably null
R0464:Ncbp3 UTSW 11 73069821 splice site probably benign
R0620:Ncbp3 UTSW 11 73049845 splice site probably benign
R2024:Ncbp3 UTSW 11 73053520 missense possibly damaging 0.95
R2121:Ncbp3 UTSW 11 73053478 missense possibly damaging 0.56
R4610:Ncbp3 UTSW 11 73079018 missense probably damaging 0.98
R4693:Ncbp3 UTSW 11 73075677 missense probably benign 0.00
R4883:Ncbp3 UTSW 11 73069752 missense probably damaging 0.99
R4974:Ncbp3 UTSW 11 73053529 critical splice donor site probably null
R5212:Ncbp3 UTSW 11 73053547 intron probably benign
R5740:Ncbp3 UTSW 11 73053497 missense possibly damaging 0.88
R5906:Ncbp3 UTSW 11 73073501 missense probably benign 0.04
R6026:Ncbp3 UTSW 11 73067722 missense probably benign 0.00
R6154:Ncbp3 UTSW 11 73049874 missense probably damaging 1.00
R6403:Ncbp3 UTSW 11 73078976 missense probably benign 0.00
R6626:Ncbp3 UTSW 11 73073384 missense possibly damaging 0.88
R6838:Ncbp3 UTSW 11 73073474 missense possibly damaging 0.89
R7155:Ncbp3 UTSW 11 73048009 missense probably damaging 0.99
R7369:Ncbp3 UTSW 11 73077921 missense probably benign 0.00
Y5379:Ncbp3 UTSW 11 73073260 small deletion probably benign
Posted On2011-07-12