Incidental Mutation 'IGL00688:1700009N14Rik'
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Institutional Source Australian Phenomics Network (link to record)
Gene Symbol 1700009N14Rik
Ensembl Gene ENSMUSG00000028287
Gene NameRIKEN cDNA 1700009N14 gene
Accession Numbers
Is this an essential gene? Probably essential (E-score: 0.951) question?
Stock #IGL00688
Quality Score
Chromosomal Location39450295-39451776 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to T at 39451443 bp
Amino Acid Change Leucine to Phenylalanine at position 216 (L216F)
Ref Sequence ENSEMBL: ENSMUSP00000029955 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000029955]
Predicted Effect probably benign
Transcript: ENSMUST00000029955
AA Change: L216F

PolyPhen 2 Score 0.013 (Sensitivity: 0.96; Specificity: 0.78)
SMART Domains Protein: ENSMUSP00000029955
Gene: ENSMUSG00000028287
AA Change: L216F

RAN 16 216 3.9e-163 SMART
Predicted Effect noncoding transcript
Transcript: ENSMUST00000169881
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 16 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Atg13 A T 2: 91,686,497 probably benign Het
Fgf7 A G 2: 126,089,445 T157A probably damaging Het
Gm13101 G T 4: 143,965,822 P203Q possibly damaging Het
Irak4 A G 15: 94,566,863 H438R possibly damaging Het
Kansl1 T C 11: 104,425,066 T49A probably damaging Het
Kcnh5 T C 12: 74,898,397 K693E probably benign Het
Nfrkb T A 9: 31,389,049 D45E probably damaging Het
Prlr T C 15: 10,322,381 probably benign Het
Prpf40b A G 15: 99,316,131 K789E probably benign Het
Reep5 A T 18: 34,349,693 S154R probably benign Het
Setx T A 2: 29,148,445 S1647R possibly damaging Het
Sptbn2 A G 19: 4,725,938 E174G probably damaging Het
Taf1 A G X: 101,562,939 E1248G probably damaging Het
Tanc1 T G 2: 59,815,391 L929R probably damaging Het
Tanc2 A G 11: 105,798,690 Y226C probably damaging Het
Tmem69 T C 4: 116,553,474 I100V probably benign Het
Other mutations in 1700009N14Rik
AlleleSourceChrCoordTypePredicted EffectPPH Score
R0308:1700009N14Rik UTSW 4 39450989 missense probably damaging 1.00
R5061:1700009N14Rik UTSW 4 39450953 missense probably benign 0.03
R5154:1700009N14Rik UTSW 4 39450938 missense probably damaging 1.00
R5507:1700009N14Rik UTSW 4 39451084 missense probably damaging 0.96
R6463:1700009N14Rik UTSW 4 39450938 missense probably damaging 0.98
R6924:1700009N14Rik UTSW 4 39450884 missense probably damaging 1.00
Posted On2012-12-06