Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL00791:Slit2'

14139

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Slit2

Ensembl Gene

ENSMUSG00000031558

Gene Name

slit guidance ligand 2

Synonyms

E030015M03Rik, Drad-1, b2b1200.1Clo, Slil3, E130320P19Rik

Accession Numbers

Essential gene?

Essential (E-score: 1.000) question?

Stock #

IGL00791

Quality Score

Status

Chromosome

Chromosomal Location

48140480-48465075 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 48461374 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Tyrosine to Histidine at position 1474 (Y1474H)

Ref Sequence

ENSEMBL: ENSMUSP00000134263 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000033967] [ENSMUST00000170109] [ENSMUST00000173107] [ENSMUST00000173686] [ENSMUST00000174313] [ENSMUST00000174421]

AlphaFold

Q9R1B9

Predicted Effect

probably benign
Transcript: ENSMUST00000033967

SMART Domains

Protein: ENSMUSP00000033967
Gene: ENSMUSG00000031558

Domain	Start	End	E-Value	Type
signal peptide	1	18	N/A	INTRINSIC
LRRNT	27	59	6.53e-9	SMART
LRR	53	77	1.41e2	SMART
LRR_TYP	78	101	1.79e-2	SMART
LRR	102	125	2.45e0	SMART
LRR	126	149	9.96e-1	SMART
LRR	154	173	1.29e2	SMART
LRR_TYP	174	197	2.05e-2	SMART
LRRCT	209	258	3.42e-9	SMART
LRRNT	272	304	4.55e-8	SMART
LRR	298	322	3e1	SMART
LRR_TYP	323	346	1.95e-3	SMART
LRR_TYP	347	370	2.24e-3	SMART
LRR	371	394	1.31e0	SMART
LRR	395	418	2.49e-1	SMART
LRRCT	430	479	1.88e-6	SMART
LRRNT	497	529	1.45e-6	SMART
LRR_TYP	549	572	1.38e-3	SMART
LRR	597	620	9.96e-1	SMART
LRR_TYP	621	644	2.71e-2	SMART
LRRCT	656	705	3.56e-7	SMART
LRRNT	718	750	3.69e-8	SMART
LRR	768	791	7.36e0	SMART
LRR_TYP	792	815	5.59e-4	SMART
LRR_TYP	816	839	7.9e-4	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000170109
AA Change: Y1465H

PolyPhen 2 Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)

SMART Domains

Protein: ENSMUSP00000127615
Gene: ENSMUSG00000031558
AA Change: Y1465H

Domain	Start	End	E-Value	Type
signal peptide	1	18	N/A	INTRINSIC
LRRNT	27	59	6.53e-9	SMART
LRR	53	77	1.41e2	SMART
LRR_TYP	78	101	1.79e-2	SMART
LRR	102	125	2.45e0	SMART
LRR	126	149	9.96e-1	SMART
LRR	154	173	1.29e2	SMART
LRR_TYP	174	197	2.05e-2	SMART
LRRCT	209	258	3.42e-9	SMART
LRRNT	272	304	4.55e-8	SMART
LRR	298	322	3e1	SMART
LRR_TYP	323	346	1.95e-3	SMART
LRR_TYP	347	370	2.24e-3	SMART
LRR	371	394	1.31e0	SMART
LRR	395	418	2.49e-1	SMART
LRRCT	430	479	1.88e-6	SMART
LRRNT	497	529	1.45e-6	SMART
LRR_TYP	549	572	1.38e-3	SMART
LRR	597	620	9.96e-1	SMART
LRR_TYP	621	644	2.71e-2	SMART
LRRCT	656	705	3.56e-7	SMART
LRRNT	718	750	3.69e-8	SMART
LRR	768	791	7.36e0	SMART
LRR_TYP	792	815	5.59e-4	SMART
LRR_TYP	816	839	7.9e-4	SMART
LRRCT	851	900	3.9e-13	SMART
EGF	913	947	3.73e-5	SMART
EGF	952	988	4.35e-6	SMART
EGF_CA	990	1026	2.21e-7	SMART
FOLN	993	1015	5.84e1	SMART
EGF	1031	1066	1.07e-5	SMART
EGF_CA	1068	1104	3.97e-9	SMART
FOLN	1116	1138	2.22e0	SMART
EGF	1116	1149	1.62e-5	SMART
LamG	1172	1308	4.82e-39	SMART
EGF	1327	1360	3.68e-4	SMART
EGF	1366	1399	3.88e-3	SMART
FOLN	1407	1429	3.34e0	SMART
EGF	1407	1440	4.46e-3	SMART
CT	1451	1520	4.23e-4	SMART

Predicted Effect

possibly damaging
Transcript: ENSMUST00000173107
AA Change: Y1453H

PolyPhen 2 Score 0.861 (Sensitivity: 0.83; Specificity: 0.93)

SMART Domains

Protein: ENSMUSP00000133840
Gene: ENSMUSG00000031558
AA Change: Y1453H

Domain	Start	End	E-Value	Type
signal peptide	1	18	N/A	INTRINSIC
LRRNT	27	59	6.53e-9	SMART
LRR	53	77	1.41e2	SMART
LRR_TYP	78	101	1.79e-2	SMART
LRR	102	125	2.45e0	SMART
LRR	126	149	9.96e-1	SMART
LRR	154	173	1.29e2	SMART
LRR_TYP	174	197	2.05e-2	SMART
LRRCT	209	258	3.42e-9	SMART
LRRNT	272	304	4.55e-8	SMART
LRR	298	322	3e1	SMART
LRR_TYP	323	346	1.95e-3	SMART
LRR_TYP	347	370	2.24e-3	SMART
LRR	371	394	1.31e0	SMART
LRR	395	418	2.49e-1	SMART
LRRCT	430	479	1.88e-6	SMART
LRRNT	505	537	1.45e-6	SMART
LRR_TYP	557	580	1.38e-3	SMART
LRR	605	628	9.96e-1	SMART
LRR_TYP	629	652	2.71e-2	SMART
LRRCT	664	713	3.56e-7	SMART
LRRNT	726	758	3.69e-8	SMART
LRR	776	799	7.36e0	SMART
LRR_TYP	800	823	5.59e-4	SMART
LRR_TYP	824	847	7.9e-4	SMART
LRRCT	859	908	3.9e-13	SMART
EGF	921	955	3.73e-5	SMART
EGF	960	996	4.35e-6	SMART
EGF_CA	998	1034	2.21e-7	SMART
FOLN	1001	1023	5.84e1	SMART
EGF	1039	1074	1.07e-5	SMART
EGF_CA	1076	1112	3.97e-9	SMART
FOLN	1124	1146	2.22e0	SMART
EGF	1124	1157	1.62e-5	SMART
LamG	1180	1316	4.82e-39	SMART
EGF	1335	1368	3.68e-4	SMART
EGF	1374	1407	3.88e-3	SMART
FOLN	1415	1437	3.34e0	SMART
EGF	1415	1448	4.46e-3	SMART
CT	1459	1528	4.23e-4	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000173686

SMART Domains

Protein: ENSMUSP00000133382
Gene: ENSMUSG00000031558

Domain	Start	End	E-Value	Type
EGF	1	31	2.05e-2	SMART
EGF	43	76	1.62e-5	SMART
Pfam:Laminin_G_2	107	149	1.4e-6	PFAM
Pfam:Laminin_G_1	107	150	5e-8	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000174313
AA Change: Y1457H

PolyPhen 2 Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)

SMART Domains

Protein: ENSMUSP00000133912
Gene: ENSMUSG00000031558
AA Change: Y1457H

Domain	Start	End	E-Value	Type
signal peptide	1	18	N/A	INTRINSIC
LRRNT	27	59	6.53e-9	SMART
LRR	53	77	1.41e2	SMART
LRR_TYP	78	101	1.79e-2	SMART
LRR	102	125	2.45e0	SMART
LRR	126	149	9.96e-1	SMART
LRR	154	173	1.29e2	SMART
LRR_TYP	174	197	2.05e-2	SMART
LRRCT	209	258	3.42e-9	SMART
LRRNT	276	308	4.55e-8	SMART
LRR	302	326	3e1	SMART
LRR_TYP	327	350	1.95e-3	SMART
LRR_TYP	351	374	2.24e-3	SMART
LRR	375	398	1.31e0	SMART
LRR	399	422	2.49e-1	SMART
LRRCT	434	483	1.88e-6	SMART
LRRNT	501	533	1.45e-6	SMART
LRR_TYP	553	576	1.38e-3	SMART
LRR	601	624	9.96e-1	SMART
LRR_TYP	625	648	2.71e-2	SMART
LRRCT	660	709	3.56e-7	SMART
LRRNT	722	754	3.69e-8	SMART
LRR	772	795	7.36e0	SMART
LRR_TYP	796	819	5.59e-4	SMART
LRR_TYP	820	843	7.9e-4	SMART
LRRCT	855	904	3.9e-13	SMART
EGF	917	951	3.73e-5	SMART
EGF	956	992	4.35e-6	SMART
EGF_CA	994	1030	2.21e-7	SMART
FOLN	997	1019	5.84e1	SMART
EGF	1035	1070	1.07e-5	SMART
EGF_CA	1072	1108	3.97e-9	SMART
FOLN	1120	1142	2.22e0	SMART
EGF	1120	1153	1.62e-5	SMART
LamG	1176	1312	4.82e-39	SMART
EGF	1331	1364	3.68e-4	SMART
EGF	1370	1403	3.88e-3	SMART
FOLN	1411	1433	3.34e0	SMART
EGF	1411	1444	4.46e-3	SMART
CT	1455	1524	4.23e-4	SMART

Predicted Effect

possibly damaging
Transcript: ENSMUST00000174421
AA Change: Y1474H

PolyPhen 2 Score 0.861 (Sensitivity: 0.83; Specificity: 0.93)

SMART Domains

Protein: ENSMUSP00000134263
Gene: ENSMUSG00000031558
AA Change: Y1474H

Domain	Start	End	E-Value	Type
signal peptide	1	18	N/A	INTRINSIC
LRRNT	27	59	6.53e-9	SMART
LRR	53	77	1.41e2	SMART
LRR_TYP	78	101	1.79e-2	SMART
LRR	102	125	2.45e0	SMART
LRR	126	149	9.96e-1	SMART
LRR	154	173	1.29e2	SMART
LRR_TYP	174	197	2.05e-2	SMART
LRRCT	209	258	3.42e-9	SMART
LRRNT	276	308	4.55e-8	SMART
LRR	302	326	3e1	SMART
LRR_TYP	327	350	1.95e-3	SMART
LRR_TYP	351	374	2.24e-3	SMART
LRR	375	398	1.31e0	SMART
LRR	399	422	2.49e-1	SMART
LRRCT	434	483	1.88e-6	SMART
LRRNT	509	541	1.45e-6	SMART
LRR_TYP	561	584	1.38e-3	SMART
LRR	609	632	9.96e-1	SMART
LRR_TYP	633	656	2.71e-2	SMART
LRRCT	668	717	3.56e-7	SMART
LRRNT	730	762	3.69e-8	SMART
LRR	780	803	7.36e0	SMART
LRR_TYP	804	827	5.59e-4	SMART
LRR_TYP	828	851	7.9e-4	SMART
LRRCT	863	912	3.9e-13	SMART
EGF	925	959	3.73e-5	SMART
EGF	964	1000	4.35e-6	SMART
EGF_CA	1002	1047	4.74e-7	SMART
FOLN	1005	1027	5.84e1	SMART
EGF	1052	1087	1.07e-5	SMART
EGF_CA	1089	1125	3.97e-9	SMART
FOLN	1137	1159	2.22e0	SMART
EGF	1137	1170	1.62e-5	SMART
LamG	1193	1329	4.82e-39	SMART
EGF	1348	1381	3.68e-4	SMART
EGF	1387	1420	3.88e-3	SMART
FOLN	1428	1450	3.34e0	SMART
EGF	1428	1461	4.46e-3	SMART
CT	1472	1541	4.23e-4	SMART

Coding Region Coverage

Validation Efficiency

MGI Phenotype

FUNCTION: The protein encoded by this gene is a member of the Slit family of secreted glycoproteins, which function as ligands for the Robo family of immunoglobulin receptors. Slit proteins play highly conserved roles in axon guidance and neuronal migration and may also have functions during other cell migration processes including leukocyte migration. In mammals, members of the slit family are characterized by an N-terminal signal peptide, four leucine-rich repeats, nine epidermal growth factor repeats, and a C-terminal cysteine knot. Mice deficient for this gene exhibit abnormal axonal projections in the embryonic forebrain and develop supernumerary uretic buds that maintain improper connections to the nephric duct. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
PHENOTYPE: Homozygous mutants display perinatal lethality, abnormal ureteric bud development, multiple fused kidneys, multiple ureters, and hydroureter. [provided by MGI curators]

Allele List at MGI

All alleles(4) : Targeted(4)

Other mutations in this stock

Total: 21 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Asap2	A	T	12: 21,289,649 (GRCm39)	M519L	possibly damaging	Het
Bbs7	T	C	3: 36,629,436 (GRCm39)	*674W	probably null	Het
Ceacam13	A	G	7: 17,747,278 (GRCm39)	T244A	possibly damaging	Het
Cln8	T	A	8: 14,944,689 (GRCm39)	M1K	probably null	Het
Cnot9	T	C	1: 74,561,533 (GRCm39)	V126A	probably benign	Het
Enpep	T	C	3: 129,125,731 (GRCm39)	T134A	possibly damaging	Het
Fastkd5	C	A	2: 130,458,297 (GRCm39)	A98S	probably benign	Het
Gsdmc	A	T	15: 63,676,284 (GRCm39)	I53N	possibly damaging	Het
Hexd	A	G	11: 121,111,986 (GRCm39)	S427G	probably benign	Het
Lrrk2	T	G	15: 91,664,044 (GRCm39)	L1927R	probably damaging	Het
Mia2	A	G	12: 59,155,085 (GRCm39)	E267G	possibly damaging	Het
Plec	A	G	15: 76,057,137 (GRCm39)	S4132P	probably damaging	Het
Rtn3	A	G	19: 7,412,434 (GRCm39)	L780P	probably damaging	Het
Serpinb9c	A	T	13: 33,335,867 (GRCm39)	V195E	probably damaging	Het
Taf15	A	G	11: 83,379,749 (GRCm39)		probably null	Het
Tbc1d17	A	G	7: 44,494,737 (GRCm39)	S194P	probably benign	Het
Tbc1d2b	T	C	9: 90,109,481 (GRCm39)	S332G	probably benign	Het
Tmpo	A	T	10: 90,998,420 (GRCm39)	S456T	possibly damaging	Het
Tubgcp2	A	G	7: 139,581,411 (GRCm39)	L608P	probably damaging	Het
Zfp39	T	A	11: 58,783,885 (GRCm39)		probably benign	Het
Zfp935	A	C	13: 62,602,278 (GRCm39)	N307K	probably benign	Het

Other mutations in Slit2

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00809:Slit2	APN	5	48,146,493 (GRCm39)	missense	possibly damaging	0.88
IGL00811:Slit2	APN	5	48,146,493 (GRCm39)	missense	possibly damaging	0.88
IGL00813:Slit2	APN	5	48,146,493 (GRCm39)	missense	possibly damaging	0.88
IGL00815:Slit2	APN	5	48,146,493 (GRCm39)	missense	possibly damaging	0.88
IGL00816:Slit2	APN	5	48,146,493 (GRCm39)	missense	possibly damaging	0.88
IGL00817:Slit2	APN	5	48,146,493 (GRCm39)	missense	possibly damaging	0.88
IGL00819:Slit2	APN	5	48,146,493 (GRCm39)	missense	possibly damaging	0.88
IGL00820:Slit2	APN	5	48,146,493 (GRCm39)	missense	possibly damaging	0.88
IGL00822:Slit2	APN	5	48,146,493 (GRCm39)	missense	possibly damaging	0.88
IGL01077:Slit2	APN	5	48,374,785 (GRCm39)	splice site	probably null
IGL01375:Slit2	APN	5	48,439,056 (GRCm39)	splice site	probably benign
IGL01481:Slit2	APN	5	48,460,273 (GRCm39)	missense	probably benign	0.05
IGL01934:Slit2	APN	5	48,395,747 (GRCm39)	missense	possibly damaging	0.93
IGL01992:Slit2	APN	5	48,395,759 (GRCm39)	missense	probably benign	0.01
IGL02315:Slit2	APN	5	48,145,213 (GRCm39)	missense	probably damaging	0.98
IGL02328:Slit2	APN	5	48,387,646 (GRCm39)	missense	probably damaging	1.00
IGL02366:Slit2	APN	5	48,461,410 (GRCm39)	missense	possibly damaging	0.53
IGL02526:Slit2	APN	5	48,461,565 (GRCm39)	nonsense	probably null
IGL02852:Slit2	APN	5	48,402,014 (GRCm39)	missense	probably damaging	1.00
IGL02887:Slit2	APN	5	48,374,816 (GRCm39)	missense	probably benign	0.44
IGL03123:Slit2	APN	5	48,368,681 (GRCm39)	missense	probably damaging	1.00
IGL03182:Slit2	APN	5	48,377,395 (GRCm39)	missense	possibly damaging	0.77
P0025:Slit2	UTSW	5	48,461,377 (GRCm39)	missense	probably damaging	0.96
R0032:Slit2	UTSW	5	48,414,198 (GRCm39)	missense	probably damaging	0.99
R0032:Slit2	UTSW	5	48,414,198 (GRCm39)	missense	probably damaging	0.99
R0055:Slit2	UTSW	5	48,439,068 (GRCm39)	nonsense	probably null
R0055:Slit2	UTSW	5	48,439,068 (GRCm39)	nonsense	probably null
R0267:Slit2	UTSW	5	48,339,673 (GRCm39)	splice site	probably benign
R0552:Slit2	UTSW	5	48,395,721 (GRCm39)	missense	probably damaging	1.00
R0610:Slit2	UTSW	5	48,433,016 (GRCm39)	missense	possibly damaging	0.77
R0883:Slit2	UTSW	5	48,402,915 (GRCm39)	splice site	probably benign
R1390:Slit2	UTSW	5	48,374,832 (GRCm39)	missense	probably benign	0.06
R1442:Slit2	UTSW	5	48,395,725 (GRCm39)	missense	probably damaging	0.96
R1453:Slit2	UTSW	5	48,414,393 (GRCm39)	missense	possibly damaging	0.88
R1508:Slit2	UTSW	5	48,349,591 (GRCm39)	missense	probably damaging	0.98
R1639:Slit2	UTSW	5	48,416,996 (GRCm39)	missense	probably damaging	1.00
R1705:Slit2	UTSW	5	48,346,814 (GRCm39)	missense	probably damaging	0.99
R1828:Slit2	UTSW	5	48,461,372 (GRCm39)	missense	probably damaging	1.00
R1897:Slit2	UTSW	5	48,395,765 (GRCm39)	missense	probably damaging	1.00
R1908:Slit2	UTSW	5	48,439,330 (GRCm39)	missense	probably damaging	1.00
R1919:Slit2	UTSW	5	48,348,358 (GRCm39)	unclassified	probably benign
R1982:Slit2	UTSW	5	48,407,178 (GRCm39)	missense	probably damaging	1.00
R2013:Slit2	UTSW	5	48,459,832 (GRCm39)	missense	probably damaging	1.00
R2136:Slit2	UTSW	5	48,461,567 (GRCm39)	missense	probably benign	0.03
R2655:Slit2	UTSW	5	48,346,917 (GRCm39)	missense	possibly damaging	0.88
R3402:Slit2	UTSW	5	48,440,763 (GRCm39)	missense	probably damaging	0.98
R3724:Slit2	UTSW	5	48,414,225 (GRCm39)	critical splice donor site	probably null
R4176:Slit2	UTSW	5	48,394,586 (GRCm39)	splice site	probably null
R4306:Slit2	UTSW	5	48,460,125 (GRCm39)	missense	possibly damaging	0.83
R4397:Slit2	UTSW	5	48,377,423 (GRCm39)	critical splice donor site	probably null
R4525:Slit2	UTSW	5	48,407,215 (GRCm39)	missense	probably damaging	1.00
R4688:Slit2	UTSW	5	48,414,345 (GRCm39)	splice site	probably null
R5026:Slit2	UTSW	5	48,414,147 (GRCm39)	missense	probably damaging	0.99
R5138:Slit2	UTSW	5	48,439,309 (GRCm39)	missense	probably damaging	1.00
R5465:Slit2	UTSW	5	48,407,254 (GRCm39)	missense	probably damaging	1.00
R5471:Slit2	UTSW	5	48,346,897 (GRCm39)	missense	probably damaging	1.00
R5699:Slit2	UTSW	5	48,378,333 (GRCm39)	critical splice donor site	probably null
R5735:Slit2	UTSW	5	48,416,958 (GRCm39)	missense	probably damaging	1.00
R5834:Slit2	UTSW	5	48,416,989 (GRCm39)	missense	probably damaging	1.00
R5967:Slit2	UTSW	5	48,142,506 (GRCm39)	missense	probably damaging	0.99
R6150:Slit2	UTSW	5	48,461,516 (GRCm39)	missense	probably damaging	1.00
R6219:Slit2	UTSW	5	48,459,770 (GRCm39)	missense	possibly damaging	0.53
R6344:Slit2	UTSW	5	48,377,023 (GRCm39)	missense	probably benign	0.07
R6408:Slit2	UTSW	5	48,142,328 (GRCm39)	unclassified	probably benign
R6479:Slit2	UTSW	5	48,389,331 (GRCm39)	missense	probably damaging	1.00
R6526:Slit2	UTSW	5	48,461,509 (GRCm39)	missense	probably damaging	0.99
R6959:Slit2	UTSW	5	48,395,727 (GRCm39)	missense	possibly damaging	0.83
R7139:Slit2	UTSW	5	48,402,025 (GRCm39)	missense	probably benign	0.19
R7201:Slit2	UTSW	5	48,394,627 (GRCm39)	missense	probably null	0.85
R7472:Slit2	UTSW	5	48,414,180 (GRCm39)	missense	probably damaging	0.97
R7491:Slit2	UTSW	5	48,377,336 (GRCm39)	missense	probably benign	0.18
R7566:Slit2	UTSW	5	48,407,239 (GRCm39)	missense	probably damaging	0.99
R7622:Slit2	UTSW	5	48,142,547 (GRCm39)	missense	probably damaging	0.98
R7831:Slit2	UTSW	5	48,402,025 (GRCm39)	missense	probably benign	0.19
R7870:Slit2	UTSW	5	48,459,649 (GRCm39)	missense	probably damaging	0.99
R7899:Slit2	UTSW	5	48,404,527 (GRCm39)	missense	possibly damaging	0.89
R7969:Slit2	UTSW	5	48,461,378 (GRCm39)	missense	possibly damaging	0.47
R7984:Slit2	UTSW	5	48,333,465 (GRCm39)	intron	probably benign
R8021:Slit2	UTSW	5	48,459,834 (GRCm39)	nonsense	probably null
R8253:Slit2	UTSW	5	48,433,013 (GRCm39)	missense	probably benign	0.00
R8321:Slit2	UTSW	5	48,387,609 (GRCm39)	missense	probably damaging	1.00
R8426:Slit2	UTSW	5	48,382,105 (GRCm39)	missense	probably benign	0.00
R8513:Slit2	UTSW	5	48,382,050 (GRCm39)	nonsense	probably null
R8756:Slit2	UTSW	5	48,459,829 (GRCm39)	nonsense	probably null
R8796:Slit2	UTSW	5	48,460,190 (GRCm39)	missense	probably benign	0.01
R8799:Slit2	UTSW	5	48,461,524 (GRCm39)	missense	possibly damaging	0.73
R8947:Slit2	UTSW	5	48,407,140 (GRCm39)	missense	probably damaging	1.00
R9005:Slit2	UTSW	5	48,459,860 (GRCm39)	missense	possibly damaging	0.73
R9173:Slit2	UTSW	5	48,377,285 (GRCm39)	missense	probably damaging	0.98
R9310:Slit2	UTSW	5	48,349,568 (GRCm39)	missense	possibly damaging	0.59
R9365:Slit2	UTSW	5	48,461,534 (GRCm39)	missense	probably benign	0.04
Z1088:Slit2	UTSW	5	48,459,695 (GRCm39)	missense	probably damaging	1.00

Posted On

2012-12-06