Incidental Mutation 'IGL00731:Snx24'
| ID |
14179 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Snx24
|
| Ensembl Gene |
ENSMUSG00000024535 |
| Gene Name |
sorting nexing 24 |
| Synonyms |
2810011K15Rik, 5730433I16Rik |
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.087)
|
| Stock # |
IGL00731
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
18 |
| Chromosomal Location |
53378734-53523992 bp(+) (GRCm39) |
| Type of Mutation |
splice site |
| DNA Base Change (assembly) |
C to T
at 53517681 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000131423
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000025417]
[ENSMUST00000165032]
|
| AlphaFold |
Q9CRB0 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000025417
|
| SMART Domains |
Protein: ENSMUSP00000025417
Gene: ENSMUSG00000024535
| Domain | Start | End | E-Value | Type |
|---|
|
PX
|
1 |
103 |
4.19e-10 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000165032
|
| SMART Domains |
Protein: ENSMUSP00000131423
Gene: ENSMUSG00000024535
| Domain | Start | End | E-Value | Type |
|---|
|
PX
|
1 |
103 |
4.19e-10 |
SMART |
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 18 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Aars1 |
A |
G |
8: 111,771,501 (GRCm39) |
|
probably benign |
Het |
| Adcy10 |
T |
C |
1: 165,400,183 (GRCm39) |
F1531L |
probably benign |
Het |
| Cgas |
G |
A |
9: 78,342,770 (GRCm39) |
P344L |
probably damaging |
Het |
| Dab2 |
T |
C |
15: 6,465,191 (GRCm39) |
S463P |
possibly damaging |
Het |
| Ehf |
C |
T |
2: 103,097,185 (GRCm39) |
|
probably null |
Het |
| Fnbp4 |
G |
T |
2: 90,598,987 (GRCm39) |
V704L |
probably benign |
Het |
| Gbp7 |
T |
C |
3: 142,252,189 (GRCm39) |
S591P |
probably benign |
Het |
| Gpr155 |
A |
G |
2: 73,192,957 (GRCm39) |
L498P |
probably damaging |
Het |
| Igll1 |
T |
C |
16: 16,678,783 (GRCm39) |
T176A |
probably benign |
Het |
| Klk1b21 |
A |
G |
7: 43,755,347 (GRCm39) |
E182G |
possibly damaging |
Het |
| Npat |
G |
A |
9: 53,473,386 (GRCm39) |
E393K |
probably damaging |
Het |
| Npnt |
C |
T |
3: 132,610,418 (GRCm39) |
|
probably null |
Het |
| Pde2a |
A |
G |
7: 101,157,306 (GRCm39) |
Y693C |
probably benign |
Het |
| Ralgapa1 |
A |
G |
12: 55,749,237 (GRCm39) |
S1269P |
possibly damaging |
Het |
| Rasal2 |
A |
C |
1: 156,985,334 (GRCm39) |
D804E |
probably benign |
Het |
| Rdh10 |
A |
G |
1: 16,178,099 (GRCm39) |
N124D |
probably benign |
Het |
| Slit3 |
G |
T |
11: 35,512,981 (GRCm39) |
D536Y |
probably damaging |
Het |
| Spink12 |
G |
A |
18: 44,241,177 (GRCm39) |
|
probably benign |
Het |
|
| Other mutations in Snx24 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL02471:Snx24
|
APN |
18 |
53,518,241 (GRCm39) |
splice site |
probably benign |
|
|
IGL02704:Snx24
|
APN |
18 |
53,460,509 (GRCm39) |
missense |
probably benign |
|
|
R1645:Snx24
|
UTSW |
18 |
53,522,634 (GRCm39) |
missense |
probably benign |
|
|
R4900:Snx24
|
UTSW |
18 |
53,518,295 (GRCm39) |
nonsense |
probably null |
|
|
R5307:Snx24
|
UTSW |
18 |
53,473,283 (GRCm39) |
nonsense |
probably null |
|
|
R7039:Snx24
|
UTSW |
18 |
53,473,307 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7299:Snx24
|
UTSW |
18 |
53,473,244 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7301:Snx24
|
UTSW |
18 |
53,473,244 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7805:Snx24
|
UTSW |
18 |
53,522,623 (GRCm39) |
missense |
probably benign |
0.22 |
|
| Posted On |
2012-12-06 |
Incidental Mutation