Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL00807:Taar2'

14342

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Taar2

Ensembl Gene

ENSMUSG00000059763

Gene Name

trace amine-associated receptor 2

Synonyms

Gpr58

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

IGL00807

Quality Score

Status

Chromosome

Chromosomal Location

23814470-23817481 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 23816573 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Methionine to Valine at position 38 (M38V)

Ref Sequence

ENSEMBL: ENSMUSP00000078137 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000079134]

AlphaFold

Q5QD17

Predicted Effect

probably benign
Transcript: ENSMUST00000079134
AA Change: M38V

PolyPhen 2 Score 0.002 (Sensitivity: 0.99; Specificity: 0.30)

SMART Domains

Protein: ENSMUSP00000078137
Gene: ENSMUSG00000059763
AA Change: M38V

Domain	Start	End	E-Value	Type
Pfam:7TM_GPCR_Srsx	42	318	2.4e-10	PFAM
Pfam:7tm_1	48	303	2.9e-54	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 19 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abca13	A	T	11: 9,328,285 (GRCm39)	T3453S	probably benign	Het
Ahnak	T	A	19: 8,985,886 (GRCm39)	V2390E	possibly damaging	Het
Aldh8a1	A	T	10: 21,271,329 (GRCm39)	I352F	probably damaging	Het
Ccnt2	T	C	1: 127,725,628 (GRCm39)		probably benign	Het
Ccr1l1	A	T	9: 123,777,506 (GRCm39)	W314R	probably benign	Het
Cdc42bpa	A	G	1: 179,969,018 (GRCm39)	I1218V	possibly damaging	Het
Dlc1	G	A	8: 37,040,002 (GRCm39)	T1386I	probably benign	Het
Frs2	A	C	10: 116,910,791 (GRCm39)		probably benign	Het
Gria1	T	C	11: 56,902,866 (GRCm39)	Y3H	probably benign	Het
Iigp1c	C	T	18: 60,378,483 (GRCm39)	S6F	probably damaging	Het
Ints2	T	C	11: 86,123,961 (GRCm39)	N609S	probably damaging	Het
Lyst	T	A	13: 13,825,008 (GRCm39)	M1541K	possibly damaging	Het
Mmachc	A	T	4: 116,563,118 (GRCm39)	V79E	probably damaging	Het
Nfe2l2	T	C	2: 75,509,757 (GRCm39)	D21G	probably damaging	Het
Pde2a	G	A	7: 101,153,619 (GRCm39)	V436M	probably damaging	Het
Polr1has	G	T	17: 37,275,813 (GRCm39)	A132S	probably damaging	Het
Rhot1	C	T	11: 80,116,928 (GRCm39)	H101Y	probably benign	Het
Sh2d4a	T	C	8: 68,782,018 (GRCm39)		probably null	Het
Tek	A	T	4: 94,686,956 (GRCm39)	N158I	probably damaging	Het

Other mutations in Taar2

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00229:Taar2	APN	10	23,817,266 (GRCm39)	missense	possibly damaging	0.50
IGL01346:Taar2	APN	10	23,816,997 (GRCm39)	missense	probably damaging	1.00
IGL01433:Taar2	APN	10	23,816,657 (GRCm39)	missense	probably benign	0.02
IGL01782:Taar2	APN	10	23,817,042 (GRCm39)	missense	probably damaging	1.00
IGL03106:Taar2	APN	10	23,817,195 (GRCm39)	missense	probably damaging	0.99
IGL03372:Taar2	APN	10	23,817,069 (GRCm39)	missense	probably benign	0.03
R0046:Taar2	UTSW	10	23,817,393 (GRCm39)	missense	probably benign	0.00
R0046:Taar2	UTSW	10	23,817,393 (GRCm39)	missense	probably benign	0.00
R0090:Taar2	UTSW	10	23,817,393 (GRCm39)	missense	probably benign	0.00
R0101:Taar2	UTSW	10	23,817,393 (GRCm39)	missense	probably benign	0.00
R0101:Taar2	UTSW	10	23,817,393 (GRCm39)	missense	probably benign	0.00
R0103:Taar2	UTSW	10	23,817,393 (GRCm39)	missense	probably benign	0.00
R0157:Taar2	UTSW	10	23,817,389 (GRCm39)	missense	probably damaging	1.00
R0189:Taar2	UTSW	10	23,817,393 (GRCm39)	missense	probably benign	0.00
R0190:Taar2	UTSW	10	23,817,393 (GRCm39)	missense	probably benign	0.00
R0226:Taar2	UTSW	10	23,817,393 (GRCm39)	missense	probably benign	0.00
R0226:Taar2	UTSW	10	23,816,961 (GRCm39)	missense	probably damaging	1.00
R0265:Taar2	UTSW	10	23,817,393 (GRCm39)	missense	probably benign	0.00
R0267:Taar2	UTSW	10	23,817,393 (GRCm39)	missense	probably benign	0.00
R0349:Taar2	UTSW	10	23,817,407 (GRCm39)	missense	probably benign	0.01
R0349:Taar2	UTSW	10	23,817,327 (GRCm39)	missense	possibly damaging	0.79
R0426:Taar2	UTSW	10	23,817,393 (GRCm39)	missense	probably benign	0.00
R0556:Taar2	UTSW	10	23,816,793 (GRCm39)	missense	probably damaging	1.00
R0698:Taar2	UTSW	10	23,817,393 (GRCm39)	missense	probably benign	0.00
R1191:Taar2	UTSW	10	23,816,927 (GRCm39)	missense	probably damaging	1.00
R2919:Taar2	UTSW	10	23,817,454 (GRCm39)	missense	probably benign	0.00
R4615:Taar2	UTSW	10	23,817,263 (GRCm39)	missense	probably benign	0.43
R4658:Taar2	UTSW	10	23,817,401 (GRCm39)	missense	probably benign	0.04
R4766:Taar2	UTSW	10	23,816,669 (GRCm39)	missense	probably damaging	0.98
R4872:Taar2	UTSW	10	23,816,591 (GRCm39)	missense	probably benign	0.02
R5205:Taar2	UTSW	10	23,816,874 (GRCm39)	missense	probably benign	0.42
R5271:Taar2	UTSW	10	23,816,930 (GRCm39)	missense	probably damaging	0.97
R5517:Taar2	UTSW	10	23,816,627 (GRCm39)	missense	possibly damaging	0.92
R6033:Taar2	UTSW	10	23,816,874 (GRCm39)	missense	probably benign
R6033:Taar2	UTSW	10	23,816,874 (GRCm39)	missense	probably benign
R6325:Taar2	UTSW	10	23,816,615 (GRCm39)	missense	probably benign	0.05
R6398:Taar2	UTSW	10	23,817,177 (GRCm39)	missense	probably benign	0.00
R6762:Taar2	UTSW	10	23,817,300 (GRCm39)	missense	probably damaging	0.98
R7121:Taar2	UTSW	10	23,816,725 (GRCm39)	missense	probably damaging	1.00
R7209:Taar2	UTSW	10	23,816,597 (GRCm39)	missense	possibly damaging	0.57
R7709:Taar2	UTSW	10	23,816,621 (GRCm39)	missense	probably benign	0.00
R8045:Taar2	UTSW	10	23,817,386 (GRCm39)	missense	probably damaging	1.00
R8223:Taar2	UTSW	10	23,817,248 (GRCm39)	missense	probably damaging	1.00
R8743:Taar2	UTSW	10	23,817,369 (GRCm39)	missense	probably damaging	1.00
R9307:Taar2	UTSW	10	23,817,237 (GRCm39)	missense	probably damaging	1.00
R9350:Taar2	UTSW	10	23,817,345 (GRCm39)	missense	probably damaging	1.00
R9351:Taar2	UTSW	10	23,816,900 (GRCm39)	missense	probably benign	0.14
R9755:Taar2	UTSW	10	23,817,038 (GRCm39)	missense	probably damaging	1.00
Z1176:Taar2	UTSW	10	23,817,084 (GRCm39)	missense	possibly damaging	0.94

Posted On

2012-12-06