Incidental Mutation 'IGL00771:Taar7b'
| ID |
14344 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Taar7b
|
| Ensembl Gene |
ENSMUSG00000095171 |
| Gene Name |
trace amine-associated receptor 7B |
| Synonyms |
LOC209517 |
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.128)
|
| Stock # |
IGL00771
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
10 |
| Chromosomal Location |
23875837-23876913 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 23876096 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Glutamic Acid
at position 87
(V87E)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000090328
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000092658]
|
| AlphaFold |
Q5QD11 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000092658
AA Change: V87E
PolyPhen 2
Score 0.014 (Sensitivity: 0.96; Specificity: 0.79)
|
| SMART Domains |
Protein: ENSMUSP00000090328
Gene: ENSMUSG00000095171
AA Change: V87E
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:7TM_GPCR_Srx
|
56 |
261 |
1.9e-7 |
PFAM |
|
Pfam:7tm_1
|
64 |
326 |
7.3e-59 |
PFAM |
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 34 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 9830107B12Rik |
A |
G |
17: 48,452,855 (GRCm39) |
L28S |
possibly damaging |
Het |
| Abca13 |
T |
A |
11: 9,240,870 (GRCm39) |
L911Q |
probably damaging |
Het |
| Armc9 |
C |
A |
1: 86,127,557 (GRCm39) |
|
probably null |
Het |
| Asxl2 |
A |
G |
12: 3,524,560 (GRCm39) |
H196R |
probably damaging |
Het |
| Atm |
T |
C |
9: 53,404,354 (GRCm39) |
D1329G |
probably benign |
Het |
| Cds2 |
T |
C |
2: 132,146,272 (GRCm39) |
|
probably benign |
Het |
| Cep295 |
A |
T |
9: 15,233,861 (GRCm39) |
C2184S |
probably damaging |
Het |
| Cpeb2 |
T |
C |
5: 43,394,890 (GRCm39) |
F623L |
possibly damaging |
Het |
| Dmd |
G |
A |
X: 82,951,978 (GRCm39) |
|
probably null |
Het |
| F11r |
T |
A |
1: 171,290,510 (GRCm39) |
|
probably null |
Het |
| Gbp3 |
C |
T |
3: 142,271,005 (GRCm39) |
|
probably benign |
Het |
| Gpc4 |
A |
G |
X: 51,163,527 (GRCm39) |
S119P |
possibly damaging |
Het |
| H2-M10.2 |
A |
G |
17: 36,597,288 (GRCm39) |
L9P |
probably damaging |
Het |
| Ica1l |
T |
C |
1: 60,053,106 (GRCm39) |
D144G |
probably damaging |
Het |
| Jaml |
A |
G |
9: 45,005,105 (GRCm39) |
K124E |
possibly damaging |
Het |
| Lamc2 |
T |
C |
1: 153,005,802 (GRCm39) |
N950S |
probably benign |
Het |
| Ltbp1 |
A |
T |
17: 75,669,511 (GRCm39) |
D1099V |
probably damaging |
Het |
| Mlxipl |
C |
T |
5: 135,161,632 (GRCm39) |
T517I |
probably damaging |
Het |
| Nbeal1 |
C |
T |
1: 60,274,512 (GRCm39) |
R308C |
probably benign |
Het |
| Nlrp1a |
A |
T |
11: 71,013,567 (GRCm39) |
L561* |
probably null |
Het |
| Prom1 |
A |
T |
5: 44,187,118 (GRCm39) |
|
probably benign |
Het |
| Ptprc |
T |
A |
1: 138,041,415 (GRCm39) |
E148V |
probably benign |
Het |
| Rap1gap |
T |
C |
4: 137,443,835 (GRCm39) |
V224A |
probably damaging |
Het |
| Slc7a6 |
T |
C |
8: 106,905,872 (GRCm39) |
S35P |
probably benign |
Het |
| Snx17 |
C |
T |
5: 31,354,679 (GRCm39) |
R314C |
probably damaging |
Het |
| Spats2l |
T |
C |
1: 57,982,231 (GRCm39) |
L371P |
probably damaging |
Het |
| Spsb1 |
C |
T |
4: 149,991,564 (GRCm39) |
M1I |
probably null |
Het |
| Sv2a |
G |
A |
3: 96,100,600 (GRCm39) |
V661I |
probably benign |
Het |
| Tcf7l2 |
G |
A |
19: 55,905,853 (GRCm39) |
V292I |
probably damaging |
Het |
| Teddm1b |
T |
A |
1: 153,750,340 (GRCm39) |
C50S |
possibly damaging |
Het |
| Trmt10a |
A |
G |
3: 137,856,216 (GRCm39) |
D159G |
probably benign |
Het |
| Urod |
T |
C |
4: 116,847,581 (GRCm39) |
N336S |
probably damaging |
Het |
| Usp8 |
A |
G |
2: 126,567,353 (GRCm39) |
|
probably null |
Het |
| Zfp182 |
A |
G |
X: 20,896,896 (GRCm39) |
Y467H |
probably damaging |
Het |
|
| Other mutations in Taar7b |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00330:Taar7b
|
APN |
10 |
23,876,740 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01662:Taar7b
|
APN |
10 |
23,875,874 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL02186:Taar7b
|
APN |
10 |
23,875,879 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02399:Taar7b
|
APN |
10 |
23,876,050 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02514:Taar7b
|
APN |
10 |
23,876,882 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02601:Taar7b
|
APN |
10 |
23,876,204 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02717:Taar7b
|
APN |
10 |
23,876,258 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02724:Taar7b
|
APN |
10 |
23,876,581 (GRCm39) |
missense |
probably benign |
|
|
IGL02725:Taar7b
|
APN |
10 |
23,875,961 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0103:Taar7b
|
UTSW |
10 |
23,876,192 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2060:Taar7b
|
UTSW |
10 |
23,876,573 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R4973:Taar7b
|
UTSW |
10 |
23,876,243 (GRCm39) |
missense |
probably benign |
0.08 |
|
R5055:Taar7b
|
UTSW |
10 |
23,876,845 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R5068:Taar7b
|
UTSW |
10 |
23,876,359 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5069:Taar7b
|
UTSW |
10 |
23,876,359 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5070:Taar7b
|
UTSW |
10 |
23,876,359 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5205:Taar7b
|
UTSW |
10 |
23,875,916 (GRCm39) |
missense |
probably benign |
0.05 |
|
R5994:Taar7b
|
UTSW |
10 |
23,876,246 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6131:Taar7b
|
UTSW |
10 |
23,876,615 (GRCm39) |
missense |
probably benign |
0.20 |
|
R6302:Taar7b
|
UTSW |
10 |
23,876,158 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
R6332:Taar7b
|
UTSW |
10 |
23,875,849 (GRCm39) |
missense |
probably benign |
0.05 |
|
R6809:Taar7b
|
UTSW |
10 |
23,876,756 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7126:Taar7b
|
UTSW |
10 |
23,875,960 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R7520:Taar7b
|
UTSW |
10 |
23,876,381 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8962:Taar7b
|
UTSW |
10 |
23,876,359 (GRCm39) |
missense |
probably benign |
0.00 |
|
| Posted On |
2012-12-06 |
Incidental Mutation