Incidental Mutation 'IGL00685:Tas2r102'
ID14369
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Tas2r102
Ensembl Gene ENSMUSG00000056901
Gene Nametaste receptor, type 2, member 102
SynonymsTas2r2, mt2r51, mGR02, STC 9-7
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.036) question?
Stock #IGL00685
Quality Score
Status
Chromosome6
Chromosomal Location132762131-132763174 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to G at 132762525 bp
ZygosityHeterozygous
Amino Acid Change Asparagine to Serine at position 132 (N132S)
Ref Sequence ENSEMBL: ENSMUSP00000068332 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000069268]
Predicted Effect possibly damaging
Transcript: ENSMUST00000069268
AA Change: N132S

PolyPhen 2 Score 0.579 (Sensitivity: 0.88; Specificity: 0.91)
SMART Domains Protein: ENSMUSP00000068332
Gene: ENSMUSG00000056901
AA Change: N132S

DomainStartEndE-ValueType
Pfam:TAS2R 21 317 3.6e-100 PFAM
Predicted Effect noncoding transcript
Transcript: ENSMUST00000204939
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 5 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Foxn2 T C 17: 88,462,877 S51P probably benign Het
Fra10ac1 T A 19: 38,201,564 K217N probably damaging Het
Klra9 T A 6: 130,182,406 I215F probably damaging Het
Manea A G 4: 26,340,578 L128P probably damaging Het
Odf2l A T 3: 145,127,873 N138Y possibly damaging Het
Other mutations in Tas2r102
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01777:Tas2r102 APN 6 132762852 missense probably damaging 0.98
IGL01956:Tas2r102 APN 6 132762453 nonsense probably null
IGL02126:Tas2r102 APN 6 132762644 missense probably damaging 1.00
IGL02650:Tas2r102 APN 6 132762210 missense probably null 0.00
R0483:Tas2r102 UTSW 6 132762365 missense probably damaging 1.00
R0573:Tas2r102 UTSW 6 132762673 missense probably damaging 0.98
R0726:Tas2r102 UTSW 6 132762452 missense probably damaging 1.00
R1777:Tas2r102 UTSW 6 132762291 missense probably benign 0.08
R3615:Tas2r102 UTSW 6 132762818 nonsense probably null
R3616:Tas2r102 UTSW 6 132762818 nonsense probably null
R4556:Tas2r102 UTSW 6 132762915 missense probably damaging 1.00
R4633:Tas2r102 UTSW 6 132762679 missense possibly damaging 0.87
R4724:Tas2r102 UTSW 6 132762557 missense probably damaging 0.97
R5268:Tas2r102 UTSW 6 132762397 missense probably damaging 0.98
R5494:Tas2r102 UTSW 6 132763143 missense probably benign 0.12
Posted On2012-12-06