Incidental Mutation 'IGL00795:Tas2r131'
| ID |
14372 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Tas2r131
|
| Ensembl Gene |
ENSMUSG00000057699 |
| Gene Name |
taste receptor, type 2, member 131 |
| Synonyms |
Tas2r31, mGR31, T2R31, mt2r61 |
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
IGL00795
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
6 |
| Chromosomal Location |
132933875-132934807 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to A
at 132934554 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Isoleucine
at position 85
(T85I)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000080736
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000082085]
|
| AlphaFold |
Q7M708 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000082085
AA Change: T85I
PolyPhen 2
Score 0.943 (Sensitivity: 0.80; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000080736
Gene: ENSMUSG00000057699
AA Change: T85I
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:TAS2R
|
1 |
293 |
1.2e-66 |
PFAM |
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 15 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 5031410I06Rik |
T |
C |
5: 26,309,153 (GRCm39) |
R50G |
probably damaging |
Het |
| Ap1m1 |
A |
G |
8: 73,007,353 (GRCm39) |
N308S |
probably damaging |
Het |
| Bub1 |
A |
G |
2: 127,663,735 (GRCm39) |
V222A |
probably benign |
Het |
| Ccdc91 |
G |
T |
6: 147,409,305 (GRCm39) |
D4Y |
probably damaging |
Het |
| Defb21 |
A |
G |
2: 152,416,665 (GRCm39) |
D47G |
probably benign |
Het |
| Dnah17 |
C |
A |
11: 117,984,460 (GRCm39) |
C1607F |
probably benign |
Het |
| Hycc2 |
C |
T |
1: 58,591,338 (GRCm39) |
E102K |
probably damaging |
Het |
| Insc |
T |
C |
7: 114,441,389 (GRCm39) |
L401P |
probably damaging |
Het |
| Kif18a |
A |
T |
2: 109,123,365 (GRCm39) |
N213I |
probably damaging |
Het |
| Mapre1 |
A |
G |
2: 153,588,234 (GRCm39) |
D19G |
probably damaging |
Het |
| Mettl8 |
A |
T |
2: 70,812,434 (GRCm39) |
I32N |
probably damaging |
Het |
| Mroh9 |
T |
A |
1: 162,888,191 (GRCm39) |
T295S |
probably damaging |
Het |
| Pum3 |
T |
A |
19: 27,399,758 (GRCm39) |
Y225F |
probably damaging |
Het |
| Tbcd |
T |
G |
11: 121,507,758 (GRCm39) |
I1193S |
probably benign |
Het |
| Tgoln1 |
C |
T |
6: 72,593,235 (GRCm39) |
A82T |
probably benign |
Het |
|
| Other mutations in Tas2r131 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00592:Tas2r131
|
APN |
6 |
132,934,159 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01023:Tas2r131
|
APN |
6 |
132,934,764 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02439:Tas2r131
|
APN |
6 |
132,934,732 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0335:Tas2r131
|
UTSW |
6 |
132,934,792 (GRCm39) |
missense |
probably benign |
|
|
R0523:Tas2r131
|
UTSW |
6 |
132,934,414 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R1056:Tas2r131
|
UTSW |
6 |
132,934,030 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R1069:Tas2r131
|
UTSW |
6 |
132,934,788 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4073:Tas2r131
|
UTSW |
6 |
132,934,802 (GRCm39) |
nonsense |
probably null |
|
|
R4719:Tas2r131
|
UTSW |
6 |
132,933,936 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5002:Tas2r131
|
UTSW |
6 |
132,934,114 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5049:Tas2r131
|
UTSW |
6 |
132,934,540 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5635:Tas2r131
|
UTSW |
6 |
132,934,571 (GRCm39) |
missense |
probably benign |
0.27 |
|
R5905:Tas2r131
|
UTSW |
6 |
132,934,639 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6028:Tas2r131
|
UTSW |
6 |
132,934,639 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6229:Tas2r131
|
UTSW |
6 |
132,933,985 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7115:Tas2r131
|
UTSW |
6 |
132,934,567 (GRCm39) |
missense |
probably benign |
0.07 |
|
R7561:Tas2r131
|
UTSW |
6 |
132,933,921 (GRCm39) |
missense |
probably benign |
0.26 |
|
R7741:Tas2r131
|
UTSW |
6 |
132,934,438 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R7810:Tas2r131
|
UTSW |
6 |
132,934,705 (GRCm39) |
missense |
probably benign |
0.11 |
|
R8878:Tas2r131
|
UTSW |
6 |
132,934,467 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9506:Tas2r131
|
UTSW |
6 |
132,934,024 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
X0025:Tas2r131
|
UTSW |
6 |
132,934,501 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Tas2r131
|
UTSW |
6 |
132,933,960 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Posted On |
2012-12-06 |
Incidental Mutation