Incidental Mutation 'IGL00870:Vmn1r13'
ID14781
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Vmn1r13
Ensembl Gene ENSMUSG00000064259
Gene Namevomeronasal 1 receptor 13
SynonymsV1rc5
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.060) question?
Stock #IGL00870
Quality Score
Status
Chromosome6
Chromosomal Location57203290-57214799 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to T at 57210113 bp
ZygosityHeterozygous
Amino Acid Change Methionine to Leucine at position 86 (M86L)
Ref Sequence ENSEMBL: ENSMUSP00000154429 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000078885] [ENSMUST00000226892] [ENSMUST00000227298] [ENSMUST00000227421]
Predicted Effect probably benign
Transcript: ENSMUST00000078885
AA Change: M86L

PolyPhen 2 Score 0.105 (Sensitivity: 0.93; Specificity: 0.86)
SMART Domains Protein: ENSMUSP00000077924
Gene: ENSMUSG00000064259
AA Change: M86L

DomainStartEndE-ValueType
Pfam:V1R 28 294 3.3e-58 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000226892
AA Change: M86L

PolyPhen 2 Score 0.105 (Sensitivity: 0.93; Specificity: 0.86)
Predicted Effect probably benign
Transcript: ENSMUST00000227298
AA Change: M86L

PolyPhen 2 Score 0.105 (Sensitivity: 0.93; Specificity: 0.86)
Predicted Effect probably benign
Transcript: ENSMUST00000227421
AA Change: M86L

PolyPhen 2 Score 0.105 (Sensitivity: 0.93; Specificity: 0.86)
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 31 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Ahnak T A 19: 9,013,698 D4115E probably damaging Het
Asb5 T C 8: 54,583,660 probably null Het
Cpeb3 A T 19: 37,054,295 I569N probably damaging Het
Cpsf7 T C 19: 10,539,650 probably null Het
Dlat A G 9: 50,650,869 L285P probably damaging Het
Dytn T C 1: 63,677,113 probably benign Het
Ears2 A T 7: 122,055,676 L123Q probably damaging Het
Gad2 T C 2: 22,629,971 V212A probably benign Het
Gon4l T C 3: 88,857,185 Y358H probably damaging Het
Gys1 T C 7: 45,448,013 probably null Het
Hnrnpm C A 17: 33,649,902 R517L probably damaging Het
Krtap20-2 G A 16: 89,205,987 G25D unknown Het
Lrif1 T C 3: 106,734,641 probably null Het
Naip2 A G 13: 100,152,060 probably benign Het
Olfr884 A T 9: 38,047,740 I173F probably damaging Het
Oxct1 T A 15: 4,101,818 L396Q probably damaging Het
Pclo A T 5: 14,539,983 R766W unknown Het
Pkhd1 T A 1: 20,571,390 I275F probably damaging Het
Rxfp3 A G 15: 11,036,215 F357S probably damaging Het
Rxfp3 A G 15: 11,036,305 V327A probably damaging Het
Serpinb2 A G 1: 107,523,070 I181V probably damaging Het
Smad5 A G 13: 56,723,667 D25G probably benign Het
Strada A G 11: 106,171,257 L82P probably damaging Het
Tek T A 4: 94,873,081 Y1079* probably null Het
Tenm3 T C 8: 48,417,132 T209A probably benign Het
Tnks1bp1 C T 2: 85,062,236 Q836* probably null Het
Toporsl T C 4: 52,610,172 S22P probably benign Het
Ttc17 T C 2: 94,371,733 probably null Het
Ttc39a A G 4: 109,442,345 probably benign Het
Vangl1 T C 3: 102,189,440 D60G probably damaging Het
Vmn1r220 C T 13: 23,184,477 M16I probably null Het
Other mutations in Vmn1r13
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01511:Vmn1r13 APN 6 57210329 missense probably benign 0.00
IGL02412:Vmn1r13 APN 6 57210489 missense possibly damaging 0.46
IGL02455:Vmn1r13 APN 6 57210472 missense probably damaging 1.00
IGL03046:Vmn1r13 APN 6 57210732 missense probably benign
R0285:Vmn1r13 UTSW 6 57209994 missense probably benign 0.06
R0304:Vmn1r13 UTSW 6 57210626 missense probably benign 0.01
R0385:Vmn1r13 UTSW 6 57210705 missense probably benign 0.06
R0402:Vmn1r13 UTSW 6 57210098 missense possibly damaging 0.96
R0544:Vmn1r13 UTSW 6 57210263 missense probably benign
R0960:Vmn1r13 UTSW 6 57210011 missense probably benign 0.06
R1297:Vmn1r13 UTSW 6 57210407 missense probably damaging 0.99
R4056:Vmn1r13 UTSW 6 57209985 missense probably benign 0.03
R5108:Vmn1r13 UTSW 6 57209916 missense probably benign 0.33
R6388:Vmn1r13 UTSW 6 57209918 missense probably benign 0.01
R7136:Vmn1r13 UTSW 6 57210254 missense not run
X0066:Vmn1r13 UTSW 6 57210597 missense possibly damaging 0.90
Posted On2012-12-06