Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL00845:Zfp599'

14982

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Zfp599

Ensembl Gene

ENSMUSG00000062794

Gene Name

zinc finger protein 599

Synonyms

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.069) question?

Stock #

IGL00845

Quality Score

Status

Chromosome

Chromosomal Location

22158726-22171191 bp(-) (GRCm39)

Type of Mutation

splice site

DNA Base Change (assembly)

T to A at 22162814 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000083462 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000086281]

AlphaFold

E9PWP1

Predicted Effect

probably benign
Transcript: ENSMUST00000086281

SMART Domains

Protein: ENSMUSP00000083462
Gene: ENSMUSG00000062794

Domain	Start	End	E-Value	Type
KRAB	4	64	5.35e-33	SMART
ZnF_C2H2	228	250	5.59e-4	SMART
ZnF_C2H2	256	278	2.43e-4	SMART
ZnF_C2H2	284	306	1.69e-3	SMART
ZnF_C2H2	312	334	8.94e-3	SMART
ZnF_C2H2	340	362	8.47e-4	SMART
ZnF_C2H2	368	390	5.06e-2	SMART
ZnF_C2H2	396	418	7.9e-4	SMART
ZnF_C2H2	424	446	7.67e-2	SMART
ZnF_C2H2	452	474	1.64e-1	SMART
ZnF_C2H2	480	503	7.37e-4	SMART

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 17 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abca14	A	G	7: 119,823,174 (GRCm39)		probably benign	Het
Dnah8	T	A	17: 31,038,250 (GRCm39)		probably null	Het
Hmcn1	G	A	1: 150,480,757 (GRCm39)	S4473F	probably damaging	Het
Mcf2	T	A	X: 59,172,446 (GRCm39)	D429V	probably damaging	Het
Myo15a	A	G	11: 60,368,605 (GRCm39)	D455G	probably damaging	Het
Myom1	T	C	17: 71,391,424 (GRCm39)	Y978H	probably damaging	Het
Naglu	A	G	11: 100,967,778 (GRCm39)	E576G	possibly damaging	Het
Rbm20	T	C	19: 53,806,380 (GRCm39)	Y487H	probably damaging	Het
Slc12a1	T	A	2: 125,030,158 (GRCm39)	C577S	probably damaging	Het
Slc34a2	T	C	5: 53,215,696 (GRCm39)		probably benign	Het
Sulf1	C	T	1: 12,867,191 (GRCm39)	T125I	probably damaging	Het
Tbc1d21	C	T	9: 58,269,745 (GRCm39)	V198I	possibly damaging	Het
Tcp11l2	T	C	10: 84,440,847 (GRCm39)	V351A	possibly damaging	Het
Tdrd6	T	C	17: 43,937,607 (GRCm39)	D1147G	probably benign	Het
Tmem185a	A	T	X: 69,505,923 (GRCm39)		probably null	Het
Vps50	C	T	6: 3,532,177 (GRCm39)	Q227*	probably null	Het
Zmym4	A	G	4: 126,794,406 (GRCm39)	V908A	probably benign	Het

Other mutations in Zfp599

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00580:Zfp599	APN	9	22,160,768 (GRCm39)	missense	possibly damaging	0.94
R0136:Zfp599	UTSW	9	22,161,038 (GRCm39)	missense	probably benign	0.13
R0239:Zfp599	UTSW	9	22,161,055 (GRCm39)	missense	probably damaging	1.00
R0239:Zfp599	UTSW	9	22,161,055 (GRCm39)	missense	probably damaging	1.00
R0421:Zfp599	UTSW	9	22,161,843 (GRCm39)	splice site	probably benign
R1699:Zfp599	UTSW	9	22,161,700 (GRCm39)	missense	probably benign	0.20
R1723:Zfp599	UTSW	9	22,169,361 (GRCm39)	missense	probably damaging	1.00
R1899:Zfp599	UTSW	9	22,162,845 (GRCm39)	missense	probably benign	0.00
R4231:Zfp599	UTSW	9	22,161,041 (GRCm39)	nonsense	probably null
R4233:Zfp599	UTSW	9	22,161,041 (GRCm39)	nonsense	probably null
R4236:Zfp599	UTSW	9	22,161,041 (GRCm39)	nonsense	probably null
R4931:Zfp599	UTSW	9	22,169,419 (GRCm39)	missense	probably damaging	0.98
R5117:Zfp599	UTSW	9	22,161,396 (GRCm39)	nonsense	probably null
R5615:Zfp599	UTSW	9	22,165,165 (GRCm39)	missense	probably benign
R5759:Zfp599	UTSW	9	22,160,957 (GRCm39)	missense	probably damaging	1.00
R5915:Zfp599	UTSW	9	22,161,130 (GRCm39)	missense	probably damaging	1.00
R6184:Zfp599	UTSW	9	22,160,947 (GRCm39)	missense	probably benign	0.18
R6188:Zfp599	UTSW	9	22,161,286 (GRCm39)	missense	probably damaging	1.00
R6657:Zfp599	UTSW	9	22,161,538 (GRCm39)	missense	probably damaging	1.00
R6736:Zfp599	UTSW	9	22,161,140 (GRCm39)	missense	probably damaging	1.00
R6752:Zfp599	UTSW	9	22,160,840 (GRCm39)	missense	probably damaging	1.00
R7071:Zfp599	UTSW	9	22,169,392 (GRCm39)	missense	probably benign	0.38
R7643:Zfp599	UTSW	9	22,161,188 (GRCm39)	missense	probably benign	0.19
R7714:Zfp599	UTSW	9	22,161,811 (GRCm39)	missense	probably benign	0.07
R7951:Zfp599	UTSW	9	22,160,764 (GRCm39)	missense	probably damaging	1.00
R7967:Zfp599	UTSW	9	22,160,830 (GRCm39)	missense	possibly damaging	0.66
R8014:Zfp599	UTSW	9	22,160,777 (GRCm39)	missense	probably benign	0.03
R8187:Zfp599	UTSW	9	22,161,111 (GRCm39)	nonsense	probably null
R9562:Zfp599	UTSW	9	22,160,999 (GRCm39)	missense	probably damaging	0.98
R9684:Zfp599	UTSW	9	22,160,824 (GRCm39)	missense	probably damaging	1.00
R9722:Zfp599	UTSW	9	22,160,741 (GRCm39)	missense	probably damaging	0.96
RF005:Zfp599	UTSW	9	22,165,180 (GRCm39)	missense	probably benign	0.03
RF024:Zfp599	UTSW	9	22,165,180 (GRCm39)	missense	probably benign	0.03

Posted On

2012-12-06