Incidental Mutation 'IGL01760:Ighv9-1'
ID153248
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Ighv9-1
Ensembl Gene ENSMUSG00000096805
Gene Nameimmunoglobulin heavy variable 9-1
SynonymsGm16987
Accession Numbers
Is this an essential gene? Not available question?
Stock #IGL01760
Quality Score
Status
Chromosome12
Chromosomal Location114093928-114094358 bp(-) (GRCm38)
Type of Mutationnonsense
DNA Base Change (assembly) C to A at 114094194 bp
ZygosityHeterozygous
Amino Acid Change Glutamic Acid to Stop codon at position 29 (E29*)
Ref Sequence ENSEMBL: ENSMUSP00000141346 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000103471] [ENSMUST00000195884]
Predicted Effect probably null
Transcript: ENSMUST00000103471
AA Change: E10*
SMART Domains Protein: ENSMUSP00000100252
Gene: ENSMUSG00000096805
AA Change: E10*

DomainStartEndE-ValueType
IGv 17 98 9.37e-27 SMART
Predicted Effect noncoding transcript
Transcript: ENSMUST00000192430
Predicted Effect probably null
Transcript: ENSMUST00000195884
AA Change: E29*
SMART Domains Protein: ENSMUSP00000141346
Gene: ENSMUSG00000096805
AA Change: E29*

DomainStartEndE-ValueType
signal peptide 1 19 N/A INTRINSIC
IGv 36 117 3.9e-29 SMART
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 28 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Adgre5 T A 8: 83,731,957 T147S probably benign Het
BC030867 T C 11: 102,255,596 C233R probably benign Het
Chst3 A T 10: 60,186,470 V185D probably damaging Het
Col14a1 A C 15: 55,423,459 D892A unknown Het
Dopey1 A G 9: 86,519,923 T1059A probably benign Het
Erlec1 A C 11: 30,934,731 S441A probably benign Het
Frmd4b G T 6: 97,308,702 T289N probably damaging Het
Gm2016 A T 12: 87,877,021 probably benign Het
Gm6133 G A 18: 78,350,175 R128Q probably benign Het
Gnai2 A G 9: 107,616,518 S155P probably damaging Het
Hspg2 T C 4: 137,512,671 S517P possibly damaging Het
Lrp1 T C 10: 127,573,501 K1583R probably benign Het
Ltbp1 C T 17: 75,227,150 T211M probably damaging Het
Mttp A G 3: 138,111,736 S418P probably benign Het
Napa A G 7: 16,098,744 N23S possibly damaging Het
Odf2 C A 2: 29,914,460 Q347K probably damaging Het
Ogdhl A G 14: 32,339,937 D504G probably damaging Het
Olfr433 T C 1: 174,042,625 L225P probably damaging Het
Pdxdc1 A T 16: 13,859,152 N273K probably damaging Het
Rslcan18 T C 13: 67,113,951 I11V probably benign Het
Spidr G T 16: 15,912,560 R664S possibly damaging Het
Tead3 T C 17: 28,333,081 N385S probably benign Het
Trim13 T A 14: 61,605,723 N396K probably benign Het
Trp53bp2 C T 1: 182,448,428 A160V possibly damaging Het
Vmn2r69 A G 7: 85,406,864 S689P possibly damaging Het
Vmn2r79 A T 7: 87,002,158 Q255L probably benign Het
Wsb1 T C 11: 79,242,041 Y276C probably damaging Het
Zfp236 G T 18: 82,621,422 N1233K probably damaging Het
Other mutations in Ighv9-1
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01295:Ighv9-1 APN 12 114093999 missense probably damaging 1.00
R4031:Ighv9-1 UTSW 12 114094224 missense probably benign 0.01
R6147:Ighv9-1 UTSW 12 114094220 missense probably damaging 0.99
R6538:Ighv9-1 UTSW 12 114094065 missense possibly damaging 0.89
Posted On2014-02-04