Incidental Mutation 'IGL01778:Erv3'
ID153763
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Erv3
Ensembl Gene ENSMUSG00000037482
Gene Nameendogenous retroviral sequence 3
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.075) question?
Stock #IGL01778
Quality Score
Status
Chromosome2
Chromosomal Location131853678-131859747 bp(-) (GRCm38)
Type of Mutationnonsense
DNA Base Change (assembly) T to A at 131855957 bp
ZygosityHeterozygous
Amino Acid Change Arginine to Stop codon at position 161 (R161*)
Ref Sequence ENSEMBL: ENSMUSP00000047030 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000040941]
Predicted Effect probably null
Transcript: ENSMUST00000040941
AA Change: R161*
SMART Domains Protein: ENSMUSP00000047030
Gene: ENSMUSG00000037482
AA Change: R161*

DomainStartEndE-ValueType
signal peptide 1 19 N/A INTRINSIC
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 38 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Actrt2 T C 4: 154,666,705 K325E probably benign Het
Arc C T 15: 74,672,355 M6I probably benign Het
Atp7b A T 8: 21,994,828 D1404E probably benign Het
BC030867 T C 11: 102,255,596 C233R probably benign Het
Cdk5rap1 T A 2: 154,366,036 N156I probably damaging Het
Ctsa T C 2: 164,834,310 probably benign Het
Depdc1b T G 13: 108,362,327 N181K probably benign Het
Epg5 T C 18: 78,019,274 V1994A probably damaging Het
Epyc T A 10: 97,681,237 C312* probably null Het
Fhdc1 G A 3: 84,444,735 A1061V possibly damaging Het
Gfra3 T C 18: 34,691,591 T280A possibly damaging Het
Gldn A T 9: 54,334,492 probably null Het
Gm6768 T C 12: 119,262,496 noncoding transcript Het
Gtf3c4 G A 2: 28,835,088 R211C probably damaging Het
Hsh2d A G 8: 72,193,507 D16G probably damaging Het
Klk15 T A 7: 43,938,838 M190K probably damaging Het
Klri1 A G 6: 129,717,047 S26P possibly damaging Het
Krt78 T A 15: 101,950,967 D265V probably damaging Het
Lgr5 A C 10: 115,462,702 I355S probably damaging Het
Lig3 T A 11: 82,794,541 V595D probably damaging Het
Map2k6 A C 11: 110,512,869 probably benign Het
Mdm4 A G 1: 132,994,547 S286P probably benign Het
Olfr320 A G 11: 58,684,269 Y132C probably damaging Het
Pofut1 T A 2: 153,248,528 M114K probably damaging Het
Rdh13 C T 7: 4,430,389 probably null Het
Reg3g T A 6: 78,466,833 I131F probably benign Het
Slc26a4 C T 12: 31,528,854 probably benign Het
Slc8a2 T A 7: 16,158,893 F827I probably damaging Het
Slfn9 A T 11: 82,987,374 C310S probably damaging Het
Sypl A G 12: 32,975,642 Y235C probably damaging Het
Trav7-4 A T 14: 53,461,641 T82S possibly damaging Het
Trim28 T A 7: 13,030,702 V782D probably damaging Het
Ttn G A 2: 76,744,898 T25217M probably damaging Het
Usp6nl A G 2: 6,427,570 T260A possibly damaging Het
Vmn2r54 A T 7: 12,632,082 N308K probably benign Het
Xdh T C 17: 73,900,280 E986G probably benign Het
Zfp770 T C 2: 114,196,238 D450G probably damaging Het
Zw10 T G 9: 49,069,615 S438R probably benign Het
Other mutations in Erv3
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL02034:Erv3 APN 2 131856014 missense possibly damaging 0.46
F5770:Erv3 UTSW 2 131855926 missense possibly damaging 0.66
R1518:Erv3 UTSW 2 131856163 missense probably benign 0.04
R6036:Erv3 UTSW 2 131856005 missense possibly damaging 0.46
R6036:Erv3 UTSW 2 131856005 missense possibly damaging 0.46
R6045:Erv3 UTSW 2 131856022 missense probably damaging 0.97
R6988:Erv3 UTSW 2 131855966 missense possibly damaging 0.90
V7580:Erv3 UTSW 2 131855926 missense possibly damaging 0.66
V7581:Erv3 UTSW 2 131855926 missense possibly damaging 0.66
V7582:Erv3 UTSW 2 131855926 missense possibly damaging 0.66
V7583:Erv3 UTSW 2 131855926 missense possibly damaging 0.66
Posted On2014-02-04