Incidental Mutation 'IGL01785:Phf21b'
ID153790
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Phf21b
Ensembl Gene ENSMUSG00000016624
Gene NamePHD finger protein 21B
SynonymsA730032D07Rik
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.233) question?
Stock #IGL01785
Quality Score
Status
Chromosome15
Chromosomal Location84785381-84856049 bp(-) (GRCm38)
Type of Mutationsplice site
DNA Base Change (assembly) C to A at 84808061 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000124941 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000016768] [ENSMUST00000159939] [ENSMUST00000162044]
Predicted Effect probably benign
Transcript: ENSMUST00000016768
SMART Domains Protein: ENSMUSP00000016768
Gene: ENSMUSG00000016624

DomainStartEndE-ValueType
low complexity region 188 202 N/A INTRINSIC
PHD 297 340 6.64e-10 SMART
coiled coil region 368 403 N/A INTRINSIC
low complexity region 456 467 N/A INTRINSIC
Predicted Effect probably benign
Transcript: ENSMUST00000159939
SMART Domains Protein: ENSMUSP00000125355
Gene: ENSMUSG00000016624

DomainStartEndE-ValueType
low complexity region 200 214 N/A INTRINSIC
PHD 309 352 6.64e-10 SMART
coiled coil region 380 415 N/A INTRINSIC
low complexity region 468 479 N/A INTRINSIC
Predicted Effect noncoding transcript
Transcript: ENSMUST00000160389
Predicted Effect probably benign
Transcript: ENSMUST00000162044
SMART Domains Protein: ENSMUSP00000124941
Gene: ENSMUSG00000016624

DomainStartEndE-ValueType
low complexity region 200 214 N/A INTRINSIC
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 30 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Abcb4 T A 5: 8,915,058 Y309* probably null Het
Abhd18 G A 3: 40,905,904 R42Q probably damaging Het
Ano3 T A 2: 110,682,715 Q645L probably damaging Het
Clasp1 T A 1: 118,497,736 L272Q possibly damaging Het
Clec1b A G 6: 129,403,562 D115G probably damaging Het
Clec2e A T 6: 129,093,401 probably benign Het
Corin T C 5: 72,339,876 N532S probably damaging Het
Csn1s2b A G 5: 87,809,913 K2R possibly damaging Het
Mcm8 A G 2: 132,827,948 D314G probably benign Het
Mga T A 2: 119,902,912 D80E probably damaging Het
Msh4 A G 3: 153,857,507 L744P probably damaging Het
Myof A T 19: 37,980,423 L348* probably null Het
Olfr1348 T C 7: 6,501,900 I109V probably benign Het
Olfr530 T A 7: 140,373,125 M162L probably benign Het
Otud3 T C 4: 138,896,897 D278G probably benign Het
Pdpr C A 8: 111,129,656 H670Q probably damaging Het
Polr3a G A 14: 24,484,120 Q106* probably null Het
Ptprm G T 17: 66,685,623 N1366K probably damaging Het
Slc10a5 G A 3: 10,335,199 P134S probably benign Het
Slc30a9 A G 5: 67,346,238 probably benign Het
Stat6 T A 10: 127,657,227 V576D probably damaging Het
Tmem132d T C 5: 127,984,315 I408V probably benign Het
Tmem50a T C 4: 134,898,447 E153G probably damaging Het
Tmod4 A G 3: 95,125,618 T22A probably benign Het
Tmprss7 C T 16: 45,680,634 G268D probably damaging Het
Tor1a A G 2: 30,963,703 probably null Het
Ttc29 T C 8: 78,282,341 L280P probably damaging Het
Tusc5 G A 11: 76,680,466 V103I probably benign Het
Usp20 A G 2: 31,017,163 E594G probably benign Het
Vmn1r31 A C 6: 58,472,724 M3R possibly damaging Het
Other mutations in Phf21b
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL02311:Phf21b APN 15 84793894 critical splice donor site probably null
IGL02700:Phf21b APN 15 84803461 missense probably benign 0.00
IGL03201:Phf21b APN 15 84787247 missense probably benign 0.32
R0113:Phf21b UTSW 15 84804767 missense probably damaging 1.00
R1464:Phf21b UTSW 15 84804959 missense probably damaging 0.99
R1464:Phf21b UTSW 15 84804959 missense probably damaging 0.99
R1529:Phf21b UTSW 15 84797396 missense probably damaging 1.00
R1834:Phf21b UTSW 15 84797346 missense probably damaging 1.00
R1854:Phf21b UTSW 15 84854762 missense probably benign 0.41
R3683:Phf21b UTSW 15 84798690 missense probably damaging 1.00
R4729:Phf21b UTSW 15 84854741 nonsense probably null
R5476:Phf21b UTSW 15 84787265 missense probably benign
R5526:Phf21b UTSW 15 84791805 missense probably benign 0.00
R5659:Phf21b UTSW 15 84793900 nonsense probably null
R6208:Phf21b UTSW 15 84795116 missense probably damaging 0.97
R6281:Phf21b UTSW 15 84854745 missense probably benign 0.02
R6288:Phf21b UTSW 15 84855071 intron probably benign
R6322:Phf21b UTSW 15 84787379 missense possibly damaging 0.94
R6875:Phf21b UTSW 15 84787446 missense probably damaging 1.00
Posted On2014-02-04