Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01813:Vmn1r183'

154303

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn1r183

Ensembl Gene

ENSMUSG00000066723

Gene Name

vomeronasal 1 receptor 183

Synonyms

V1rd15, LOC209824

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.054) question?

Stock #

IGL01813

Quality Score

Status

Chromosome

Chromosomal Location

23754199-23755116 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 23754985 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Phenylalanine to Isoleucine at position 263 (F263I)

Ref Sequence

ENSEMBL: ENSMUSP00000083176 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000086012]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000086012
AA Change: F263I

PolyPhen 2 Score 0.192 (Sensitivity: 0.92; Specificity: 0.87)

SMART Domains

Protein: ENSMUSP00000083176
Gene: ENSMUSG00000066723
AA Change: F263I

Domain	Start	End	E-Value	Type
Pfam:TAS2R	8	297	5.6e-15	PFAM
Pfam:7tm_1	31	285	1.4e-9	PFAM
Pfam:V1R	41	296	2.5e-18	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000205855

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 32 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abcb11	T	A	2: 69,117,936 (GRCm39)		probably benign	Het
Adgrb2	T	C	4: 129,906,359 (GRCm39)	V929A	probably benign	Het
Aldh2	T	C	5: 121,710,136 (GRCm39)	I400V	probably benign	Het
Atxn2l	T	C	7: 126,099,425 (GRCm39)	D84G	probably damaging	Het
Avpr1a	T	A	10: 122,284,916 (GRCm39)	N69K	probably damaging	Het
BC034090	G	A	1: 155,102,085 (GRCm39)	Q60*	probably null	Het
Bltp1	G	A	3: 36,982,669 (GRCm39)	S778N	possibly damaging	Het
Bub3	T	C	7: 131,170,362 (GRCm39)	S295P	probably benign	Het
Cacna1b	T	C	2: 24,499,902 (GRCm39)	S161G	probably damaging	Het
Clba1	C	T	12: 112,779,179 (GRCm39)	T272M	probably damaging	Het
Col6a4	T	A	9: 105,954,452 (GRCm39)	S296C	probably damaging	Het
Cyp4f15	G	A	17: 32,905,131 (GRCm39)	R38H	probably benign	Het
Dync2h1	T	C	9: 7,122,799 (GRCm39)	I2052M	probably damaging	Het
Gm11627	T	C	11: 102,469,634 (GRCm39)		probably benign	Het
Jmjd8	A	T	17: 26,048,212 (GRCm39)		probably null	Het
Kmt2c	A	G	5: 25,495,802 (GRCm39)	V629A	possibly damaging	Het
Kremen1	T	C	11: 5,149,667 (GRCm39)	T335A	probably benign	Het
Oosp2	T	C	19: 11,628,847 (GRCm39)	T85A	probably benign	Het
Or12d17	A	G	17: 37,777,649 (GRCm39)	E184G	probably damaging	Het
Or8s10	A	G	15: 98,335,530 (GRCm39)	Y60C	possibly damaging	Het
Pex5l	T	C	3: 33,136,204 (GRCm39)	E5G	probably benign	Het
Pigk	A	T	3: 152,448,156 (GRCm39)	Q173L	probably damaging	Het
Pik3c2g	T	A	6: 139,599,407 (GRCm39)	N174K	possibly damaging	Het
Plb1	C	T	5: 32,486,429 (GRCm39)	H893Y	probably damaging	Het
Pus7	T	C	5: 23,965,302 (GRCm39)		probably benign	Het
R3hdm1	G	A	1: 128,102,970 (GRCm39)		probably null	Het
Samd7	C	T	3: 30,808,435 (GRCm39)	P83S	probably benign	Het
Supt5	T	A	7: 28,023,400 (GRCm39)	Y293F	probably damaging	Het
Tbc1d30	T	C	10: 121,102,956 (GRCm39)	D692G	probably benign	Het
Tmpo	G	A	10: 90,999,104 (GRCm39)	R228C	probably benign	Het
Tnn	A	T	1: 159,916,008 (GRCm39)	H1236Q	probably damaging	Het
Ubr3	T	C	2: 69,781,914 (GRCm39)	I667T	probably benign	Het

Other mutations in Vmn1r183

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00987:Vmn1r183	APN	7	23,754,649 (GRCm39)	missense	probably damaging	1.00
IGL03377:Vmn1r183	APN	7	23,754,817 (GRCm39)	missense	possibly damaging	0.70
PIT4791001:Vmn1r183	UTSW	7	23,754,266 (GRCm39)	missense	probably damaging	0.99
R0463:Vmn1r183	UTSW	7	23,754,926 (GRCm39)	missense	probably damaging	1.00
R0616:Vmn1r183	UTSW	7	23,754,250 (GRCm39)	missense	probably benign	0.03
R0666:Vmn1r183	UTSW	7	23,754,601 (GRCm39)	missense	probably benign
R3928:Vmn1r183	UTSW	7	23,754,997 (GRCm39)	missense	probably damaging	0.98
R4425:Vmn1r183	UTSW	7	23,754,973 (GRCm39)	missense	probably benign	0.00
R4767:Vmn1r183	UTSW	7	23,754,531 (GRCm39)	frame shift	probably null
R4835:Vmn1r183	UTSW	7	23,754,564 (GRCm39)	missense	probably benign	0.07
R5267:Vmn1r183	UTSW	7	23,754,971 (GRCm39)	missense	possibly damaging	0.90
R5693:Vmn1r183	UTSW	7	23,754,227 (GRCm39)	missense	possibly damaging	0.94
R6291:Vmn1r183	UTSW	7	23,754,982 (GRCm39)	missense	possibly damaging	0.70
R6439:Vmn1r183	UTSW	7	23,754,704 (GRCm39)	missense	possibly damaging	0.73
R7073:Vmn1r183	UTSW	7	23,754,926 (GRCm39)	missense	probably damaging	1.00
R8732:Vmn1r183	UTSW	7	23,754,890 (GRCm39)	missense	possibly damaging	0.89

Posted On

2014-02-04