Incidental Mutation 'IGL01818:Gm4922'
| ID |
154446 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Gm4922
|
| Ensembl Gene |
ENSMUSG00000044624 |
| Gene Name |
predicted gene 4922 |
| Synonyms |
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
IGL01818
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
10 |
| Chromosomal Location |
18655475-18662541 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 18660701 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Glycine
at position 7
(D7G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000149756
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000055107]
[ENSMUST00000216654]
|
| AlphaFold |
Q8C0N0 |
| Predicted Effect |
unknown
Transcript: ENSMUST00000055107
AA Change: D7G
|
| SMART Domains |
Protein: ENSMUSP00000055273
Gene: ENSMUSG00000044624
AA Change: D7G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
3 |
13 |
N/A |
INTRINSIC |
|
S_TKc
|
28 |
275 |
1.92e-75 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000215162
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000216654
AA Change: D7G
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 22 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Agrp |
T |
C |
8: 106,294,018 (GRCm39) |
D35G |
probably benign |
Het |
| C3ar1 |
T |
C |
6: 122,827,378 (GRCm39) |
N280D |
probably benign |
Het |
| Ccpg1 |
A |
G |
9: 72,904,735 (GRCm39) |
T15A |
probably damaging |
Het |
| Chmp7 |
A |
G |
14: 69,956,616 (GRCm39) |
V361A |
probably damaging |
Het |
| Dnmbp |
T |
A |
19: 43,889,604 (GRCm39) |
K721M |
probably damaging |
Het |
| Elmod3 |
T |
C |
6: 72,563,490 (GRCm39) |
E46G |
possibly damaging |
Het |
| H2-T24 |
C |
A |
17: 36,328,128 (GRCm39) |
|
probably benign |
Het |
| Hal |
A |
T |
10: 93,326,846 (GRCm39) |
T161S |
probably damaging |
Het |
| Htr1d |
A |
G |
4: 136,170,197 (GRCm39) |
E142G |
probably benign |
Het |
| Minar1 |
T |
C |
9: 89,483,366 (GRCm39) |
E677G |
probably damaging |
Het |
| Mrps31 |
T |
C |
8: 22,901,483 (GRCm39) |
M1T |
probably null |
Het |
| Nckap1l |
T |
C |
15: 103,386,709 (GRCm39) |
L628P |
probably damaging |
Het |
| Oosp2 |
T |
C |
19: 11,627,053 (GRCm39) |
N90S |
probably benign |
Het |
| Pitpnm3 |
A |
G |
11: 72,003,077 (GRCm39) |
|
probably benign |
Het |
| Ppox |
A |
T |
1: 171,108,318 (GRCm39) |
I6K |
probably benign |
Het |
| Skint6 |
G |
T |
4: 112,805,766 (GRCm39) |
Q690K |
probably benign |
Het |
| Stat1 |
T |
C |
1: 52,190,437 (GRCm39) |
I564T |
probably damaging |
Het |
| Tiam1 |
T |
A |
16: 89,664,592 (GRCm39) |
I539F |
probably damaging |
Het |
| Tmem191 |
A |
G |
16: 17,095,594 (GRCm39) |
R35G |
possibly damaging |
Het |
| Trim30d |
A |
T |
7: 104,121,267 (GRCm39) |
C343S |
probably damaging |
Het |
| Trpm3 |
T |
C |
19: 22,891,838 (GRCm39) |
L736S |
probably damaging |
Het |
| Vmn2r73 |
T |
A |
7: 85,519,109 (GRCm39) |
|
probably benign |
Het |
|
| Other mutations in Gm4922 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01810:Gm4922
|
APN |
10 |
18,659,795 (GRCm39) |
missense |
probably benign |
0.20 |
|
IGL01931:Gm4922
|
APN |
10 |
18,660,042 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02021:Gm4922
|
APN |
10 |
18,660,225 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02573:Gm4922
|
APN |
10 |
18,659,423 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL03305:Gm4922
|
APN |
10 |
18,659,232 (GRCm39) |
nonsense |
probably null |
|
|
R0149:Gm4922
|
UTSW |
10 |
18,659,289 (GRCm39) |
missense |
probably benign |
0.10 |
|
R0361:Gm4922
|
UTSW |
10 |
18,659,289 (GRCm39) |
missense |
probably benign |
0.10 |
|
R0564:Gm4922
|
UTSW |
10 |
18,659,813 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R1079:Gm4922
|
UTSW |
10 |
18,660,086 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1163:Gm4922
|
UTSW |
10 |
18,659,469 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R1164:Gm4922
|
UTSW |
10 |
18,659,469 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R1398:Gm4922
|
UTSW |
10 |
18,659,496 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R1458:Gm4922
|
UTSW |
10 |
18,659,640 (GRCm39) |
nonsense |
probably null |
|
|
R1867:Gm4922
|
UTSW |
10 |
18,660,211 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R1994:Gm4922
|
UTSW |
10 |
18,659,388 (GRCm39) |
missense |
probably benign |
0.10 |
|
R2146:Gm4922
|
UTSW |
10 |
18,659,264 (GRCm39) |
missense |
probably benign |
|
|
R2437:Gm4922
|
UTSW |
10 |
18,659,829 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3551:Gm4922
|
UTSW |
10 |
18,660,244 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3939:Gm4922
|
UTSW |
10 |
18,660,362 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4580:Gm4922
|
UTSW |
10 |
18,659,432 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4602:Gm4922
|
UTSW |
10 |
18,660,007 (GRCm39) |
nonsense |
probably null |
|
|
R4704:Gm4922
|
UTSW |
10 |
18,660,567 (GRCm39) |
missense |
probably benign |
0.20 |
|
R4790:Gm4922
|
UTSW |
10 |
18,659,916 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R5478:Gm4922
|
UTSW |
10 |
18,659,885 (GRCm39) |
missense |
probably benign |
|
|
R5510:Gm4922
|
UTSW |
10 |
18,659,745 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5694:Gm4922
|
UTSW |
10 |
18,660,035 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R6080:Gm4922
|
UTSW |
10 |
18,660,500 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6869:Gm4922
|
UTSW |
10 |
18,660,263 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6923:Gm4922
|
UTSW |
10 |
18,659,616 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7667:Gm4922
|
UTSW |
10 |
18,660,096 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8198:Gm4922
|
UTSW |
10 |
18,659,340 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8270:Gm4922
|
UTSW |
10 |
18,659,760 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8310:Gm4922
|
UTSW |
10 |
18,659,536 (GRCm39) |
missense |
probably benign |
0.09 |
|
R9454:Gm4922
|
UTSW |
10 |
18,660,329 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Posted On |
2014-02-04 |
Incidental Mutation