Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01793:Vmn1r83'

155266

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn1r83

Ensembl Gene

ENSMUSG00000066804

Gene Name

vomeronasal 1 receptor 83

Synonyms

V1rg8

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.063) question?

Stock #

IGL01793

Quality Score

Status

Chromosome

Chromosomal Location

12054177-12056055 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

C to T at 12055504 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Methionine to Isoleucine at position 184 (M184I)

Ref Sequence

ENSEMBL: ENSMUSP00000154521 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000086229] [ENSMUST00000226701]

AlphaFold

Q8R287

Predicted Effect

probably benign
Transcript: ENSMUST00000086229
AA Change: M184I

PolyPhen 2 Score 0.021 (Sensitivity: 0.95; Specificity: 0.80)

SMART Domains

Protein: ENSMUSP00000083406
Gene: ENSMUSG00000066804
AA Change: M184I

Domain	Start	End	E-Value	Type
Pfam:TAS2R	1	303	1.3e-8	PFAM
Pfam:V1R	26	299	1.7e-28	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000226701
AA Change: M184I

PolyPhen 2 Score 0.021 (Sensitivity: 0.95; Specificity: 0.80)

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 29 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Aox1	A	G	1: 58,375,783 (GRCm39)	I871V	possibly damaging	Het
Bbs7	A	T	3: 36,659,831 (GRCm39)		probably null	Het
D930020B18Rik	T	C	10: 121,507,736 (GRCm39)	I158T	probably damaging	Het
Drc7	T	C	8: 95,797,905 (GRCm39)	I441T	probably benign	Het
Etl4	T	C	2: 20,748,709 (GRCm39)	I147T	possibly damaging	Het
Fat1	G	A	8: 45,442,149 (GRCm39)	M1150I	probably benign	Het
Fbn1	T	C	2: 125,229,213 (GRCm39)	S523G	possibly damaging	Het
Gramd1a	C	T	7: 30,833,838 (GRCm39)		probably null	Het
Hc	A	G	2: 34,918,202 (GRCm39)	Y694H	probably damaging	Het
Kif6	T	A	17: 49,931,521 (GRCm39)	I73N	probably damaging	Het
Large1	A	G	8: 73,585,809 (GRCm39)		probably benign	Het
Luzp2	G	T	7: 54,821,997 (GRCm39)	L171F	probably damaging	Het
Naaladl1	C	A	19: 6,159,661 (GRCm39)		probably null	Het
Otop1	G	A	5: 38,457,215 (GRCm39)	A325T	possibly damaging	Het
Parp8	T	A	13: 117,047,415 (GRCm39)	Y219F	probably damaging	Het
Pkp3	A	G	7: 140,668,817 (GRCm39)	I660V	probably benign	Het
Plin3	T	C	17: 56,588,540 (GRCm39)	N238S	probably benign	Het
Ppef2	A	T	5: 92,394,615 (GRCm39)	D186E	probably damaging	Het
Rab40c	G	A	17: 26,103,596 (GRCm39)	L156F	probably damaging	Het
Scnn1a	T	C	6: 125,320,666 (GRCm39)	V547A	probably benign	Het
Spag6l	A	G	16: 16,599,721 (GRCm39)	V247A	probably damaging	Het
Syne1	T	C	10: 5,302,191 (GRCm39)	E853G	possibly damaging	Het
Synj2	C	T	17: 6,077,500 (GRCm39)	R460*	probably null	Het
Synj2	T	A	17: 6,088,321 (GRCm39)	H1457Q	probably benign	Het
Syt1	T	C	10: 108,419,836 (GRCm39)	D275G	possibly damaging	Het
Tmx1	A	G	12: 70,505,561 (GRCm39)	D108G	probably benign	Het
Vmn1r180	T	C	7: 23,652,668 (GRCm39)	V277A	probably benign	Het
Zfp750	G	T	11: 121,404,810 (GRCm39)	P22T	probably damaging	Het
Zscan2	A	G	7: 80,524,692 (GRCm39)	I138V	probably null	Het

Other mutations in Vmn1r83

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01371:Vmn1r83	APN	7	12,055,160 (GRCm39)	missense	probably benign	0.10
IGL01447:Vmn1r83	APN	7	12,055,424 (GRCm39)	missense	probably benign
IGL02137:Vmn1r83	APN	7	12,055,761 (GRCm39)	missense	probably damaging	1.00
IGL03155:Vmn1r83	APN	7	12,055,617 (GRCm39)	missense	probably benign
IGL03182:Vmn1r83	APN	7	12,055,617 (GRCm39)	missense	probably benign
R0627:Vmn1r83	UTSW	7	12,055,919 (GRCm39)	missense	probably damaging	0.99
R1511:Vmn1r83	UTSW	7	12,055,197 (GRCm39)	missense	possibly damaging	0.87
R3882:Vmn1r83	UTSW	7	12,055,329 (GRCm39)	missense	probably damaging	1.00
R4613:Vmn1r83	UTSW	7	12,055,695 (GRCm39)	missense	probably benign	0.00
R4678:Vmn1r83	UTSW	7	12,055,697 (GRCm39)	missense	possibly damaging	0.67
R5580:Vmn1r83	UTSW	7	12,055,800 (GRCm39)	missense	probably benign	0.01
R6982:Vmn1r83	UTSW	7	12,055,763 (GRCm39)	missense	probably damaging	1.00
R7440:Vmn1r83	UTSW	7	12,055,556 (GRCm39)	missense	probably damaging	1.00
R7476:Vmn1r83	UTSW	7	12,055,542 (GRCm39)	missense	possibly damaging	0.93
R7522:Vmn1r83	UTSW	7	12,055,505 (GRCm39)	missense	possibly damaging	0.61
R7759:Vmn1r83	UTSW	7	12,055,360 (GRCm39)	missense	probably benign	0.06
R8886:Vmn1r83	UTSW	7	12,055,843 (GRCm39)	missense	probably benign	0.10
R9077:Vmn1r83	UTSW	7	12,055,571 (GRCm39)	missense	probably damaging	1.00

Posted On

2014-02-04