Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01795:Dnaaf8'

155328

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Dnaaf8

Ensembl Gene

ENSMUSG00000022543

Gene Name

dynein axonemal assembly factor 8

Synonyms

4930451G09Rik

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.055) question?

Stock #

IGL01795

Quality Score

Status

Chromosome

Chromosomal Location

4782152-4796827 bp(+) (GRCm39)

Type of Mutation

exon

DNA Base Change (assembly)

T to G at 4791935 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Gene Model

predicted gene model for transcript(s): [ENSMUST00000090457]

AlphaFold

no structure available at present

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000090457

SMART Domains

Protein: ENSMUSP00000087942
Gene: ENSMUSG00000022543

Domain	Start	End	E-Value	Type
Pfam:DUF4701	1	195	7.5e-72	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000229669

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 28 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4930590J08Rik	C	T	6: 91,895,093 (GRCm39)	R263*	probably null	Het
Arfgef1	A	T	1: 10,217,753 (GRCm39)	I1562K	probably benign	Het
B4galt1	T	A	4: 40,807,760 (GRCm39)	D347V	probably damaging	Het
Ccdc178	T	A	18: 22,152,175 (GRCm39)	R646S	probably benign	Het
Ccr1	A	T	9: 123,764,149 (GRCm39)	L127*	probably null	Het
Cd109	A	G	9: 78,569,047 (GRCm39)		probably benign	Het
Chd6	A	G	2: 160,803,294 (GRCm39)	V2128A	probably benign	Het
Chil6	T	A	3: 106,296,108 (GRCm39)	I376F	probably damaging	Het
Chit1	T	C	1: 134,076,167 (GRCm39)	S275P	probably damaging	Het
Erap1	T	A	13: 74,814,209 (GRCm39)		probably null	Het
F5	T	C	1: 164,021,959 (GRCm39)	V1478A	probably benign	Het
Fras1	G	T	5: 96,925,904 (GRCm39)	V3703F	probably damaging	Het
Hmmr	C	T	11: 40,612,561 (GRCm39)	M185I	probably benign	Het
Kcnu1	A	G	8: 26,403,733 (GRCm39)	Y8C	probably damaging	Het
Krt16	A	G	11: 100,138,550 (GRCm39)		probably benign	Het
Mcf2l	A	G	8: 13,050,749 (GRCm39)		probably null	Het
Mgat5	C	T	1: 127,396,968 (GRCm39)	R572W	probably damaging	Het
Neil2	T	C	14: 63,426,199 (GRCm39)	D57G	probably benign	Het
Nom1	A	G	5: 29,651,869 (GRCm39)	T736A	probably benign	Het
Or4k51	A	T	2: 111,584,731 (GRCm39)	M46L	probably benign	Het
Or5m5	T	A	2: 85,814,478 (GRCm39)	I98N	probably damaging	Het
Or6p1	A	T	1: 174,258,215 (GRCm39)	I74F	possibly damaging	Het
Prr14l	A	T	5: 32,989,189 (GRCm39)		probably benign	Het
Sall1	A	G	8: 89,755,308 (GRCm39)	S1224P	probably benign	Het
Slc44a2	A	C	9: 21,256,645 (GRCm39)	K336Q	probably damaging	Het
Speer4c2	C	A	5: 15,861,884 (GRCm39)		probably benign	Het
Sptan1	C	T	2: 29,908,501 (GRCm39)	T1754I	probably benign	Het
Zdhhc5	T	C	2: 84,520,390 (GRCm39)	S596G	probably benign	Het

Other mutations in Dnaaf8

Allele	Source	Chr	Coord	Type	Predicted Effect
IGL03052:Dnaaf8	APN	16	4,795,358 (GRCm39)	splice site	noncoding transcript
R0392:Dnaaf8	UTSW	16	4,795,363 (GRCm39)	splice site	noncoding transcript
R4851:Dnaaf8	UTSW	16	4,794,138 (GRCm39)	exon	noncoding transcript
R5562:Dnaaf8	UTSW	16	4,791,940 (GRCm39)	exon	noncoding transcript
R5868:Dnaaf8	UTSW	16	4,791,932 (GRCm39)	exon	noncoding transcript

Posted On

2014-02-04