Mutagenetix > Incidental Mutation

Incidental Mutation 'R1457:Otogl'

158587

Institutional Source

Beutler Lab

Gene Symbol

Otogl

Ensembl Gene

ENSMUSG00000091455

Gene Name

otogelin-like

Synonyms

Gm6924

MMRRC Submission

039512-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R1457 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

107596392-107747995 bp(-) (GRCm39)

Type of Mutation

splice site

DNA Base Change (assembly)

A to C at 107714013 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000129467 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000165341] [ENSMUST00000165341]

AlphaFold

F7A4A7

Predicted Effect

probably null
Transcript: ENSMUST00000165341

SMART Domains

Protein: ENSMUSP00000129467
Gene: ENSMUSG00000091455

Domain	Start	End	E-Value	Type
signal peptide	1	22	N/A	INTRINSIC
EGF_like	71	101	3.36e1	SMART
VWD	104	264	4.74e-29	SMART
C8	305	378	6.13e-6	SMART
VWD	463	625	7e-41	SMART
C8	668	733	3.6e-3	SMART
Pfam:TIL	736	791	2.3e-11	PFAM
SCOP:d1coua_	833	911	1e-6	SMART
VWD	928	1085	1.29e-30	SMART
C8	1120	1194	1.81e-26	SMART
Pfam:AbfB	1230	1350	1.2e-10	PFAM
Pfam:TIL	1364	1418	6.1e-8	PFAM
VWD	1497	1671	2.34e-10	SMART
C8	1705	1775	9.56e-17	SMART
Pfam:TIL	1778	1836	1.6e-8	PFAM
low complexity region	1870	1886	N/A	INTRINSIC
CT	2242	2325	6.9e-14	SMART

Predicted Effect

probably null
Transcript: ENSMUST00000165341

SMART Domains

Protein: ENSMUSP00000129467
Gene: ENSMUSG00000091455

Domain	Start	End	E-Value	Type
signal peptide	1	22	N/A	INTRINSIC
EGF_like	71	101	3.36e1	SMART
VWD	104	264	4.74e-29	SMART
C8	305	378	6.13e-6	SMART
VWD	463	625	7e-41	SMART
C8	668	733	3.6e-3	SMART
Pfam:TIL	736	791	2.3e-11	PFAM
SCOP:d1coua_	833	911	1e-6	SMART
VWD	928	1085	1.29e-30	SMART
C8	1120	1194	1.81e-26	SMART
Pfam:AbfB	1230	1350	1.2e-10	PFAM
Pfam:TIL	1364	1418	6.1e-8	PFAM
VWD	1497	1671	2.34e-10	SMART
C8	1705	1775	9.56e-17	SMART
Pfam:TIL	1778	1836	1.6e-8	PFAM
low complexity region	1870	1886	N/A	INTRINSIC
CT	2242	2325	6.9e-14	SMART

Coding Region Coverage

1x: 98.9%
3x: 97.8%
10x: 94.7%
20x: 87.3%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene belongs to the otogelin family. This gene is expressed in the inner ear of vertebrates with the highest level of expression seen at the embryonic stage and lowest in adult. Knockdown studies in zebrafish suggest that this gene is essential for normal inner ear function. Mutations in this gene are associated with autosomal recessive deafness. [provided by RefSeq, Dec 2012]

Allele List at MGI

Other mutations in this stock

Total: 77 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abca14	A	T	7: 119,888,683 (GRCm39)	I1210F	probably benign	Het
Ankrd17	T	C	5: 90,433,705 (GRCm39)	H688R	possibly damaging	Het
Arhgap24	T	A	5: 102,811,972 (GRCm39)	N66K	probably damaging	Het
Atp1a1	C	T	3: 101,497,782 (GRCm39)	G335D	probably damaging	Het
Cacna1g	C	T	11: 94,350,381 (GRCm39)	R488H	possibly damaging	Het
Cacna1h	A	T	17: 25,616,594 (GRCm39)	V149E	probably damaging	Het
Cd22	G	T	7: 30,572,595 (GRCm39)	P338Q	probably benign	Het
Cntln	G	T	4: 85,015,076 (GRCm39)	M1122I	probably benign	Het
Cntrl	A	G	2: 35,012,768 (GRCm39)	N302S	probably benign	Het
Cog8	T	C	8: 107,779,528 (GRCm39)	R250G	probably damaging	Het
Cracdl	A	T	1: 37,665,093 (GRCm39)	Y268*	probably null	Het
Creld2	T	C	15: 88,707,956 (GRCm39)	C232R	probably damaging	Het
Cyp2b23	G	A	7: 26,372,574 (GRCm39)	P347L	probably damaging	Het
Dnah5	T	C	15: 28,403,688 (GRCm39)		probably null	Het
Eml6	C	T	11: 29,974,459 (GRCm39)	V40I	probably damaging	Het
Epb42	C	T	2: 120,860,448 (GRCm39)		probably null	Het
Fcrla	A	G	1: 170,748,573 (GRCm39)	L190P	probably damaging	Het
Galnt18	A	T	7: 111,378,635 (GRCm39)	Y40*	probably null	Het
Gdf7	A	T	12: 8,348,073 (GRCm39)	M416K	probably damaging	Het
Gm11232	T	A	4: 71,675,156 (GRCm39)		probably null	Het
Gpam	T	A	19: 55,076,608 (GRCm39)	N198Y	probably damaging	Het
Grip1	C	T	10: 119,822,255 (GRCm39)	S327F	possibly damaging	Het
Hey2	C	T	10: 30,710,352 (GRCm39)	A134T	probably benign	Het
Kat6a	T	C	8: 23,428,668 (GRCm39)	I1341T	probably benign	Het
Kcnd3	T	C	3: 105,575,502 (GRCm39)	L542P	probably benign	Het
Lars1	G	A	18: 42,343,115 (GRCm39)	R1101C	probably damaging	Het
Lman2	T	C	13: 55,499,064 (GRCm39)	D234G	probably benign	Het
Map3k19	A	C	1: 127,745,635 (GRCm39)	I1273R	probably damaging	Het
Matn1	T	A	4: 130,677,330 (GRCm39)	F180I	possibly damaging	Het
Meikin	T	A	11: 54,261,767 (GRCm39)	L61*	probably null	Het
Mroh2b	G	T	15: 4,955,166 (GRCm39)	D720Y	probably damaging	Het
Myh13	T	C	11: 67,221,872 (GRCm39)	I199T	probably damaging	Het
Myh4	T	A	11: 67,139,287 (GRCm39)	S535T	probably damaging	Het
Myo5a	T	C	9: 75,120,347 (GRCm39)	M1715T	probably damaging	Het
Nat8	A	T	6: 85,807,971 (GRCm39)	V54D	probably damaging	Het
Nbea	A	G	3: 55,992,748 (GRCm39)	V286A	probably damaging	Het
Ndnf	A	G	6: 65,680,998 (GRCm39)	K426E	possibly damaging	Het
Nup210l	T	A	3: 90,098,279 (GRCm39)	N1410K	possibly damaging	Het
Oca2	A	T	7: 55,971,269 (GRCm39)	T399S	probably damaging	Het
Or10al2	A	T	17: 37,983,816 (GRCm39)	K301*	probably null	Het
Or1af1	A	C	2: 37,109,671 (GRCm39)	T57P	possibly damaging	Het
Or51a43	A	T	7: 103,717,666 (GRCm39)	C191S	probably damaging	Het
Or52h7	T	A	7: 104,214,278 (GRCm39)	N283K	probably damaging	Het
Or8c10	G	A	9: 38,279,492 (GRCm39)	V217I	probably benign	Het
Or8j3	A	G	2: 86,028,596 (GRCm39)	S167P	probably damaging	Het
Pde4b	C	T	4: 102,462,373 (GRCm39)	T511I	probably damaging	Het
Proser3	A	G	7: 30,239,172 (GRCm39)		probably null	Het
Psmd12	G	A	11: 107,370,472 (GRCm39)	V24M	probably damaging	Het
Rbm17	A	T	2: 11,598,272 (GRCm39)	M170K	probably benign	Het
Rims2	C	T	15: 39,374,710 (GRCm39)	T1064I	possibly damaging	Het
Ripor3	C	T	2: 167,834,573 (GRCm39)	V281M	probably damaging	Het
Rreb1	C	A	13: 38,130,904 (GRCm39)	Q1353K	possibly damaging	Het
Sgo2a	A	G	1: 58,054,965 (GRCm39)	D383G	probably benign	Het
Sik3	C	T	9: 46,132,446 (GRCm39)	T1346M	probably damaging	Het
Slx1b	A	T	7: 126,291,968 (GRCm39)	V63E	probably damaging	Het
Son	A	G	16: 91,453,974 (GRCm39)	D907G	probably damaging	Het
Src	G	A	2: 157,311,132 (GRCm39)	V401M	probably damaging	Het
St3gal4	T	C	9: 34,966,053 (GRCm39)	K24E	possibly damaging	Het
Stat6	A	G	10: 127,494,114 (GRCm39)	K647R	probably damaging	Het
Tbl1xr1	G	A	3: 22,247,333 (GRCm39)		probably null	Het
Tlk2	G	A	11: 105,147,778 (GRCm39)		probably null	Het
Tmbim6	T	A	15: 99,299,496 (GRCm39)	I3K	probably benign	Het
Tmeff2	A	T	1: 51,221,026 (GRCm39)	I334F	probably damaging	Het
Ttn	T	C	2: 76,670,659 (GRCm39)		probably null	Het
Ubl7	T	A	9: 57,821,894 (GRCm39)	I81N	probably damaging	Het
Ugt1a10	A	G	1: 87,983,433 (GRCm39)	Y77C	probably damaging	Het
Uqcrfs1	A	G	13: 30,724,890 (GRCm39)	C217R	probably damaging	Het
Usp50	T	C	2: 126,603,554 (GRCm39)	T331A	probably benign	Het
Vmn1r65	A	G	7: 6,012,156 (GRCm39)	V26A	probably benign	Het
Wdfy3	A	C	5: 102,065,445 (GRCm39)	V1241G	possibly damaging	Het
Wtap	A	C	17: 13,200,631 (GRCm39)		probably null	Het
Zbtb40	C	A	4: 136,712,148 (GRCm39)	A1187S	possibly damaging	Het
Zfp57	T	C	17: 37,316,990 (GRCm39)	S20P	probably damaging	Het
Zfp592	A	G	7: 80,674,227 (GRCm39)	D397G	probably damaging	Het
Zfp747	A	T	7: 126,973,676 (GRCm39)	S165T	probably benign	Het
Zfp949	C	T	9: 88,451,891 (GRCm39)	T487I	probably damaging	Het
Zscan4d	A	G	7: 10,898,921 (GRCm39)	C119R	probably damaging	Het

Other mutations in Otogl

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
H8562:Otogl	UTSW	10	107,746,817 (GRCm39)	missense	probably benign	0.00
R0084:Otogl	UTSW	10	107,737,202 (GRCm39)	missense	probably damaging	0.96
R0164:Otogl	UTSW	10	107,710,391 (GRCm39)	missense	probably damaging	0.97
R0164:Otogl	UTSW	10	107,710,391 (GRCm39)	missense	probably damaging	0.97
R0238:Otogl	UTSW	10	107,642,557 (GRCm39)	missense	probably damaging	0.98
R0238:Otogl	UTSW	10	107,642,557 (GRCm39)	missense	probably damaging	0.98
R0239:Otogl	UTSW	10	107,642,557 (GRCm39)	missense	probably damaging	0.98
R0239:Otogl	UTSW	10	107,642,557 (GRCm39)	missense	probably damaging	0.98
R0294:Otogl	UTSW	10	107,613,089 (GRCm39)	missense	probably damaging	1.00
R0360:Otogl	UTSW	10	107,606,511 (GRCm39)	splice site	probably benign
R0442:Otogl	UTSW	10	107,712,716 (GRCm39)	missense	probably damaging	1.00
R0488:Otogl	UTSW	10	107,639,466 (GRCm39)	missense	probably benign	0.02
R0507:Otogl	UTSW	10	107,702,601 (GRCm39)	missense	possibly damaging	0.51
R0573:Otogl	UTSW	10	107,616,849 (GRCm39)	missense	probably benign	0.00
R0581:Otogl	UTSW	10	107,624,901 (GRCm39)	missense	possibly damaging	0.79
R0613:Otogl	UTSW	10	107,652,931 (GRCm39)	missense	probably damaging	0.99
R0614:Otogl	UTSW	10	107,634,216 (GRCm39)	missense	probably benign	0.14
R0742:Otogl	UTSW	10	107,702,601 (GRCm39)	missense	possibly damaging	0.51
R0846:Otogl	UTSW	10	107,608,157 (GRCm39)	missense	probably benign	0.40
R1146:Otogl	UTSW	10	107,722,374 (GRCm39)	missense	probably damaging	1.00
R1146:Otogl	UTSW	10	107,722,374 (GRCm39)	missense	probably damaging	1.00
R1439:Otogl	UTSW	10	107,615,113 (GRCm39)	missense	probably benign	0.02
R1526:Otogl	UTSW	10	107,705,387 (GRCm39)	missense	probably damaging	1.00
R1662:Otogl	UTSW	10	107,634,218 (GRCm39)	missense	possibly damaging	0.84
R1664:Otogl	UTSW	10	107,642,437 (GRCm39)	missense	probably benign	0.00
R1667:Otogl	UTSW	10	107,649,826 (GRCm39)	nonsense	probably null
R1695:Otogl	UTSW	10	107,649,878 (GRCm39)	missense	probably damaging	0.99
R1731:Otogl	UTSW	10	107,652,972 (GRCm39)	missense	probably damaging	1.00
R1733:Otogl	UTSW	10	107,619,573 (GRCm39)	missense	possibly damaging	0.46
R1764:Otogl	UTSW	10	107,735,322 (GRCm39)	nonsense	probably null
R1824:Otogl	UTSW	10	107,615,692 (GRCm39)	missense	probably benign
R1850:Otogl	UTSW	10	107,713,925 (GRCm39)	missense	probably damaging	1.00
R1856:Otogl	UTSW	10	107,690,125 (GRCm39)	missense	possibly damaging	0.92
R1875:Otogl	UTSW	10	107,735,451 (GRCm39)	missense	probably damaging	1.00
R1938:Otogl	UTSW	10	107,613,436 (GRCm39)	missense	probably damaging	0.98
R1986:Otogl	UTSW	10	107,630,051 (GRCm39)	critical splice acceptor site	probably null
R2072:Otogl	UTSW	10	107,616,904 (GRCm39)	missense	probably damaging	1.00
R2117:Otogl	UTSW	10	107,694,779 (GRCm39)	missense	probably benign	0.06
R2219:Otogl	UTSW	10	107,692,838 (GRCm39)	missense	probably damaging	1.00
R2508:Otogl	UTSW	10	107,710,361 (GRCm39)	missense	probably damaging	0.99
R2883:Otogl	UTSW	10	107,604,842 (GRCm39)	missense	probably damaging	1.00
R2931:Otogl	UTSW	10	107,655,865 (GRCm39)	missense	possibly damaging	0.85
R3620:Otogl	UTSW	10	107,710,232 (GRCm39)	missense	probably damaging	0.99
R3621:Otogl	UTSW	10	107,710,232 (GRCm39)	missense	probably damaging	0.99
R3735:Otogl	UTSW	10	107,735,390 (GRCm39)	nonsense	probably null
R3812:Otogl	UTSW	10	107,735,332 (GRCm39)	missense	probably damaging	1.00
R3880:Otogl	UTSW	10	107,663,565 (GRCm39)	missense	probably damaging	0.96
R3958:Otogl	UTSW	10	107,657,786 (GRCm39)	missense	probably damaging	1.00
R4063:Otogl	UTSW	10	107,626,510 (GRCm39)	missense	probably benign	0.02
R4064:Otogl	UTSW	10	107,626,510 (GRCm39)	missense	probably benign	0.02
R4108:Otogl	UTSW	10	107,607,105 (GRCm39)	missense	probably benign	0.01
R4352:Otogl	UTSW	10	107,705,396 (GRCm39)	missense	probably damaging	1.00
R4526:Otogl	UTSW	10	107,722,841 (GRCm39)	missense	probably damaging	1.00
R4614:Otogl	UTSW	10	107,727,985 (GRCm39)	nonsense	probably null
R4703:Otogl	UTSW	10	107,657,785 (GRCm39)	missense	probably damaging	1.00
R4741:Otogl	UTSW	10	107,615,121 (GRCm39)	missense	probably benign	0.00
R4790:Otogl	UTSW	10	107,657,894 (GRCm39)	critical splice acceptor site	probably null
R4801:Otogl	UTSW	10	107,737,197 (GRCm39)	missense	probably damaging	1.00
R4802:Otogl	UTSW	10	107,737,197 (GRCm39)	missense	probably damaging	1.00
R4910:Otogl	UTSW	10	107,715,378 (GRCm39)	missense	probably benign	0.05
R4913:Otogl	UTSW	10	107,712,716 (GRCm39)	missense	probably damaging	0.98
R5238:Otogl	UTSW	10	107,604,834 (GRCm39)	missense	probably damaging	1.00
R5261:Otogl	UTSW	10	107,613,453 (GRCm39)	missense	probably benign	0.16
R5387:Otogl	UTSW	10	107,616,794 (GRCm39)	missense	probably benign	0.03
R5395:Otogl	UTSW	10	107,652,999 (GRCm39)	missense	probably benign	0.39
R5403:Otogl	UTSW	10	107,644,617 (GRCm39)	missense	probably benign	0.08
R5482:Otogl	UTSW	10	107,657,802 (GRCm39)	missense	probably damaging	0.99
R5547:Otogl	UTSW	10	107,617,909 (GRCm39)	missense	possibly damaging	0.55
R5611:Otogl	UTSW	10	107,622,630 (GRCm39)	missense	probably damaging	1.00
R5642:Otogl	UTSW	10	107,722,413 (GRCm39)	missense	probably benign	0.44
R5690:Otogl	UTSW	10	107,612,978 (GRCm39)	synonymous	silent
R5711:Otogl	UTSW	10	107,612,978 (GRCm39)	synonymous	silent
R5731:Otogl	UTSW	10	107,717,325 (GRCm39)	missense	probably damaging	0.98
R5743:Otogl	UTSW	10	107,692,862 (GRCm39)	missense	possibly damaging	0.67
R5782:Otogl	UTSW	10	107,612,978 (GRCm39)	synonymous	silent
R5820:Otogl	UTSW	10	107,612,978 (GRCm39)	synonymous	silent
R5897:Otogl	UTSW	10	107,612,978 (GRCm39)	synonymous	silent
R6004:Otogl	UTSW	10	107,715,390 (GRCm39)	missense	probably damaging	1.00
R6145:Otogl	UTSW	10	107,612,978 (GRCm39)	synonymous	silent
R6146:Otogl	UTSW	10	107,612,978 (GRCm39)	synonymous	silent
R6147:Otogl	UTSW	10	107,612,978 (GRCm39)	synonymous	silent
R6149:Otogl	UTSW	10	107,717,314 (GRCm39)	missense	probably benign	0.36
R6226:Otogl	UTSW	10	107,607,067 (GRCm39)	nonsense	probably null
R6283:Otogl	UTSW	10	107,626,361 (GRCm39)	missense	probably damaging	0.98
R6414:Otogl	UTSW	10	107,617,911 (GRCm39)	missense	probably damaging	1.00
R6604:Otogl	UTSW	10	107,657,895 (GRCm39)	splice site	probably null
R6634:Otogl	UTSW	10	107,698,165 (GRCm39)	missense	probably damaging	1.00
R6727:Otogl	UTSW	10	107,612,978 (GRCm39)	synonymous	silent
R6755:Otogl	UTSW	10	107,689,164 (GRCm39)	nonsense	probably null
R6795:Otogl	UTSW	10	107,612,978 (GRCm39)	synonymous	silent
R6797:Otogl	UTSW	10	107,612,978 (GRCm39)	synonymous	silent
R6864:Otogl	UTSW	10	107,663,667 (GRCm39)	missense	probably damaging	0.96
R6924:Otogl	UTSW	10	107,644,502 (GRCm39)	missense	probably damaging	1.00
R6967:Otogl	UTSW	10	107,649,911 (GRCm39)	missense	probably benign	0.01
R7000:Otogl	UTSW	10	107,615,692 (GRCm39)	missense	probably benign
R7075:Otogl	UTSW	10	107,614,790 (GRCm39)	missense	probably benign	0.16
R7122:Otogl	UTSW	10	107,702,515 (GRCm39)	missense	probably benign	0.08
R7176:Otogl	UTSW	10	107,614,772 (GRCm39)	missense	probably damaging	1.00
R7184:Otogl	UTSW	10	107,599,061 (GRCm39)	missense	probably damaging	1.00
R7199:Otogl	UTSW	10	107,710,394 (GRCm39)	missense	possibly damaging	0.88
R7252:Otogl	UTSW	10	107,657,804 (GRCm39)	missense	probably benign	0.06
R7286:Otogl	UTSW	10	107,606,471 (GRCm39)	missense	probably benign	0.00
R7373:Otogl	UTSW	10	107,737,112 (GRCm39)	missense	probably damaging	1.00
R7449:Otogl	UTSW	10	107,639,524 (GRCm39)	missense	probably damaging	1.00
R7486:Otogl	UTSW	10	107,657,849 (GRCm39)	missense	probably damaging	1.00
R7493:Otogl	UTSW	10	107,722,843 (GRCm39)	missense	probably benign	0.06
R7659:Otogl	UTSW	10	107,612,981 (GRCm39)	missense	probably benign	0.19
R7732:Otogl	UTSW	10	107,642,525 (GRCm39)	missense	probably benign	0.01
R7754:Otogl	UTSW	10	107,705,407 (GRCm39)	missense	probably damaging	0.99
R7757:Otogl	UTSW	10	107,712,782 (GRCm39)	missense	probably damaging	1.00
R7800:Otogl	UTSW	10	107,722,376 (GRCm39)	missense	probably damaging	0.99
R7864:Otogl	UTSW	10	107,705,428 (GRCm39)	missense	probably damaging	1.00
R7879:Otogl	UTSW	10	107,612,970 (GRCm39)	missense	probably benign	0.00
R7941:Otogl	UTSW	10	107,642,663 (GRCm39)	splice site	probably null
R7956:Otogl	UTSW	10	107,713,887 (GRCm39)	missense	possibly damaging	0.62
R7988:Otogl	UTSW	10	107,731,637 (GRCm39)	missense	probably damaging	1.00
R8057:Otogl	UTSW	10	107,644,476 (GRCm39)	missense	probably benign	0.00
R8058:Otogl	UTSW	10	107,598,287 (GRCm39)	missense	probably damaging	1.00
R8127:Otogl	UTSW	10	107,731,613 (GRCm39)	missense	probably damaging	1.00
R8143:Otogl	UTSW	10	107,642,527 (GRCm39)	missense	probably damaging	1.00
R8310:Otogl	UTSW	10	107,613,461 (GRCm39)	missense	possibly damaging	0.94
R8319:Otogl	UTSW	10	107,689,127 (GRCm39)	critical splice donor site	probably null
R8339:Otogl	UTSW	10	107,625,397 (GRCm39)	missense	probably benign	0.34
R8339:Otogl	UTSW	10	107,625,396 (GRCm39)	missense	probably damaging	0.99
R8394:Otogl	UTSW	10	107,722,326 (GRCm39)	critical splice donor site	probably null
R8428:Otogl	UTSW	10	107,634,597 (GRCm39)	missense	probably damaging	1.00
R8444:Otogl	UTSW	10	107,692,975 (GRCm39)	missense	probably benign	0.01
R8501:Otogl	UTSW	10	107,626,421 (GRCm39)	missense	probably benign
R8503:Otogl	UTSW	10	107,727,987 (GRCm39)	missense	probably damaging	1.00
R8680:Otogl	UTSW	10	107,747,936 (GRCm39)	critical splice donor site	probably null
R9025:Otogl	UTSW	10	107,613,432 (GRCm39)	missense	probably damaging	0.99
R9090:Otogl	UTSW	10	107,652,974 (GRCm39)	missense	probably null	0.99
R9223:Otogl	UTSW	10	107,690,205 (GRCm39)	missense	probably damaging	0.99
R9268:Otogl	UTSW	10	107,616,917 (GRCm39)	missense	probably damaging	1.00
R9271:Otogl	UTSW	10	107,652,974 (GRCm39)	missense	probably null	0.99
R9356:Otogl	UTSW	10	107,617,890 (GRCm39)	missense	probably damaging	1.00
R9484:Otogl	UTSW	10	107,737,156 (GRCm39)	missense	probably damaging	1.00
R9484:Otogl	UTSW	10	107,657,894 (GRCm39)	critical splice acceptor site	probably null
R9571:Otogl	UTSW	10	107,598,364 (GRCm39)	missense	possibly damaging	0.94
R9731:Otogl	UTSW	10	107,735,328 (GRCm39)	missense	probably damaging	1.00
X0065:Otogl	UTSW	10	107,731,643 (GRCm39)	missense	probably damaging	1.00
X0067:Otogl	UTSW	10	107,702,538 (GRCm39)	missense	probably damaging	1.00
Z1176:Otogl	UTSW	10	107,614,734 (GRCm39)	missense	probably damaging	0.97
Z1176:Otogl	UTSW	10	107,613,074 (GRCm39)	missense	probably benign
Z1176:Otogl	UTSW	10	107,624,893 (GRCm39)	missense	probably benign	0.00
Z1177:Otogl	UTSW	10	107,689,258 (GRCm39)	missense	possibly damaging	0.78
Z1177:Otogl	UTSW	10	107,599,119 (GRCm39)	nonsense	probably null
Z1177:Otogl	UTSW	10	107,712,764 (GRCm39)	missense	probably benign	0.14

Predicted Primers

PCR Primer
(F):5'- TGTTCACAGTGAGCCTTCTGCAAAG -3'
(R):5'- ACTGCACCGAACATGACTGTCC -3'

Sequencing Primer
(F):5'- CCTTCTGCAAAGTGATCGTGAATC -3'
(R):5'- GAACATGACTGTCCAGGTAATCTTC -3'

Posted On

2014-03-14