Incidental Mutation 'R1463:Ly75'
| ID |
159199 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ly75
|
| Ensembl Gene |
ENSMUSG00000026980 |
| Gene Name |
lymphocyte antigen 75 |
| Synonyms |
DEC-205, CD205 |
| MMRRC Submission |
039517-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R1463 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
2 |
| Chromosomal Location |
60122447-60213617 bp(-) (GRCm39) |
| Type of Mutation |
critical splice donor site (2 bp from exon) |
| DNA Base Change (assembly) |
A to G
at 60199101 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000108152
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000028362]
[ENSMUST00000112533]
|
| AlphaFold |
Q60767 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000028362
|
| SMART Domains |
Protein: ENSMUSP00000028362
Gene: ENSMUSG00000026980
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
27 |
N/A |
INTRINSIC |
|
RICIN
|
33 |
146 |
2.63e-17 |
SMART |
|
FN2
|
162 |
209 |
1.22e-23 |
SMART |
|
CLECT
|
216 |
341 |
7.36e-32 |
SMART |
|
CLECT
|
361 |
486 |
9.28e-29 |
SMART |
|
CLECT
|
501 |
624 |
1.11e-17 |
SMART |
|
CLECT
|
643 |
791 |
1.93e-26 |
SMART |
|
CLECT
|
811 |
932 |
7.94e-2 |
SMART |
|
CLECT
|
952 |
1091 |
5.81e-21 |
SMART |
|
CLECT
|
1104 |
1222 |
1.04e-22 |
SMART |
|
CLECT
|
1240 |
1382 |
3.48e-10 |
SMART |
|
CLECT
|
1395 |
1513 |
9.59e-22 |
SMART |
|
CLECT
|
1530 |
1661 |
7.79e-22 |
SMART |
|
transmembrane domain
|
1670 |
1692 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000112533
|
| SMART Domains |
Protein: ENSMUSP00000108152
Gene: ENSMUSG00000026980
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
27 |
N/A |
INTRINSIC |
|
RICIN
|
33 |
146 |
2.63e-17 |
SMART |
|
FN2
|
162 |
209 |
1.22e-23 |
SMART |
|
CLECT
|
216 |
341 |
7.36e-32 |
SMART |
|
CLECT
|
361 |
486 |
9.28e-29 |
SMART |
|
CLECT
|
501 |
624 |
1.11e-17 |
SMART |
|
CLECT
|
643 |
791 |
1.93e-26 |
SMART |
|
CLECT
|
811 |
932 |
7.94e-2 |
SMART |
|
CLECT
|
952 |
1091 |
5.81e-21 |
SMART |
|
CLECT
|
1104 |
1222 |
1.04e-22 |
SMART |
|
CLECT
|
1240 |
1382 |
3.48e-10 |
SMART |
|
CLECT
|
1395 |
1513 |
9.59e-22 |
SMART |
|
CLECT
|
1530 |
1661 |
7.79e-22 |
SMART |
|
transmembrane domain
|
1670 |
1692 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000124654
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000151984
|
| Meta Mutation Damage Score |
0.9583 |
| Coding Region Coverage |
- 1x: 99.0%
- 3x: 98.2%
- 10x: 96.0%
- 20x: 91.6%
|
| Validation Efficiency |
97% (97/100) |
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a knock-out allele display abnormalities in CD8-positive T cell morphology and cytotoxic T cell physiology. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(7) : Targeted, knock-out(1) Targeted, other(1) Gene trapped(5)
|
| Other mutations in this stock |
Total: 100 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca5 |
A |
T |
11: 110,205,384 (GRCm39) |
I299N |
probably damaging |
Het |
| Abcc8 |
T |
C |
7: 45,803,936 (GRCm39) |
T413A |
probably benign |
Het |
| Actc1 |
G |
A |
2: 113,880,010 (GRCm39) |
S201F |
probably damaging |
Het |
| Adam30 |
G |
A |
3: 98,069,841 (GRCm39) |
C558Y |
probably damaging |
Het |
| Adcy4 |
T |
A |
14: 56,016,396 (GRCm39) |
I352F |
probably damaging |
Het |
| Adgrl4 |
A |
T |
3: 151,216,233 (GRCm39) |
D472V |
probably damaging |
Het |
| Afap1l2 |
T |
A |
19: 56,918,583 (GRCm39) |
M117L |
probably benign |
Het |
| AI597479 |
T |
C |
1: 43,152,389 (GRCm39) |
V229A |
probably damaging |
Het |
| Ascc1 |
T |
C |
10: 59,898,338 (GRCm39) |
V267A |
probably benign |
Het |
| Asxl3 |
A |
G |
18: 22,649,810 (GRCm39) |
S600G |
possibly damaging |
Het |
| Atg14 |
T |
C |
14: 47,786,451 (GRCm39) |
I268V |
probably benign |
Het |
| Bcas1 |
C |
T |
2: 170,260,584 (GRCm39) |
V32I |
probably benign |
Het |
| Cacna1c |
G |
T |
6: 118,570,955 (GRCm39) |
D2106E |
probably benign |
Het |
| Cacna1i |
A |
G |
15: 80,263,255 (GRCm39) |
H1440R |
possibly damaging |
Het |
| Catsper2 |
G |
A |
2: 121,236,927 (GRCm39) |
T240M |
probably damaging |
Het |
| Ccn4 |
T |
A |
15: 66,791,120 (GRCm39) |
N307K |
possibly damaging |
Het |
| Cd163 |
A |
G |
6: 124,288,406 (GRCm39) |
E279G |
probably damaging |
Het |
| Cdx2 |
C |
T |
5: 147,243,470 (GRCm39) |
S108N |
probably benign |
Het |
| Cenpf |
A |
T |
1: 189,386,936 (GRCm39) |
N1781K |
probably damaging |
Het |
| Cgref1 |
T |
A |
5: 31,093,338 (GRCm39) |
|
probably benign |
Het |
| Clcn4 |
C |
T |
7: 7,299,763 (GRCm39) |
W22* |
probably null |
Het |
| Cntn2 |
A |
G |
1: 132,448,875 (GRCm39) |
|
probably null |
Het |
| Cntn5 |
C |
T |
9: 9,673,801 (GRCm39) |
|
probably null |
Het |
| Cpeb3 |
A |
G |
19: 37,116,500 (GRCm39) |
M377T |
probably benign |
Het |
| Cryge |
T |
A |
1: 65,087,997 (GRCm39) |
R135* |
probably null |
Het |
| Ctdsp2 |
C |
A |
10: 126,829,790 (GRCm39) |
|
probably benign |
Het |
| Ctsll3 |
G |
A |
13: 60,949,089 (GRCm39) |
|
probably benign |
Het |
| Cuzd1 |
C |
A |
7: 130,918,371 (GRCm39) |
G189C |
probably damaging |
Het |
| Dmbt1 |
T |
A |
7: 130,711,366 (GRCm39) |
|
probably null |
Het |
| Dnai4 |
T |
A |
4: 102,944,615 (GRCm39) |
L245F |
possibly damaging |
Het |
| Dnajc13 |
A |
T |
9: 104,056,139 (GRCm39) |
S1587R |
probably damaging |
Het |
| Dock4 |
GCTCAGTGTATC |
GC |
12: 40,866,324 (GRCm39) |
|
probably null |
Het |
| Dock6 |
T |
C |
9: 21,743,202 (GRCm39) |
H701R |
probably damaging |
Het |
| Edem3 |
A |
G |
1: 151,683,261 (GRCm39) |
T646A |
possibly damaging |
Het |
| Esrra |
A |
C |
19: 6,889,823 (GRCm39) |
D160E |
probably benign |
Het |
| Fbn2 |
T |
C |
18: 58,143,452 (GRCm39) |
T2868A |
probably benign |
Het |
| Galnt7 |
T |
A |
8: 58,105,892 (GRCm39) |
M41L |
probably benign |
Het |
| Gbf1 |
T |
C |
19: 46,259,984 (GRCm39) |
|
probably benign |
Het |
| Glyat |
A |
G |
19: 12,625,467 (GRCm39) |
N63S |
probably damaging |
Het |
| Gm9376 |
A |
T |
14: 118,504,894 (GRCm39) |
M109L |
probably benign |
Het |
| H2-M10.3 |
A |
G |
17: 36,677,612 (GRCm39) |
V222A |
probably damaging |
Het |
| Ifna12 |
T |
G |
4: 88,521,193 (GRCm39) |
D118A |
possibly damaging |
Het |
| Inpp5j |
T |
C |
11: 3,451,147 (GRCm39) |
M501V |
probably benign |
Het |
| Itpr3 |
C |
T |
17: 27,336,128 (GRCm39) |
|
probably benign |
Het |
| Ivns1abp |
A |
G |
1: 151,237,291 (GRCm39) |
N527S |
probably benign |
Het |
| Kif13a |
T |
C |
13: 47,083,088 (GRCm39) |
T4A |
possibly damaging |
Het |
| Kif3b |
T |
C |
2: 153,172,073 (GRCm39) |
*748Q |
probably null |
Het |
| Klf8 |
C |
T |
X: 152,167,677 (GRCm39) |
Q241* |
probably null |
Het |
| Kras |
A |
T |
6: 145,170,787 (GRCm39) |
|
probably benign |
Het |
| Lamc3 |
C |
A |
2: 31,777,423 (GRCm39) |
T23K |
probably benign |
Het |
| Lrrc74b |
T |
A |
16: 17,377,737 (GRCm39) |
H47L |
probably benign |
Het |
| Map3k21 |
G |
A |
8: 126,668,876 (GRCm39) |
G821S |
probably benign |
Het |
| Mettl14 |
A |
G |
3: 123,167,722 (GRCm39) |
|
probably benign |
Het |
| Mettl5 |
T |
C |
2: 69,715,590 (GRCm39) |
|
probably benign |
Het |
| Mier3 |
A |
G |
13: 111,848,289 (GRCm39) |
D301G |
probably damaging |
Het |
| Mipep |
T |
C |
14: 61,025,595 (GRCm39) |
|
probably benign |
Het |
| Mmp21 |
T |
C |
7: 133,277,588 (GRCm39) |
|
probably null |
Het |
| Msh4 |
A |
G |
3: 153,563,207 (GRCm39) |
L723P |
probably damaging |
Het |
| Muc5b |
T |
C |
7: 141,412,817 (GRCm39) |
V1921A |
unknown |
Het |
| Myo1e |
G |
A |
9: 70,246,038 (GRCm39) |
E410K |
possibly damaging |
Het |
| Nav2 |
T |
G |
7: 49,185,710 (GRCm39) |
I951S |
probably damaging |
Het |
| Npc1 |
G |
A |
18: 12,324,887 (GRCm39) |
T1202I |
probably damaging |
Het |
| Or10j3 |
A |
G |
1: 173,030,934 (GRCm39) |
K4E |
probably benign |
Het |
| Or2ab1 |
A |
G |
11: 58,488,947 (GRCm39) |
R242G |
probably damaging |
Het |
| Or5a3 |
C |
T |
19: 12,400,252 (GRCm39) |
T193I |
probably benign |
Het |
| Pacc1 |
T |
C |
1: 191,060,486 (GRCm39) |
|
probably benign |
Het |
| Patl2 |
C |
T |
2: 121,954,216 (GRCm39) |
V452M |
probably benign |
Het |
| Pcdh18 |
A |
G |
3: 49,709,854 (GRCm39) |
V487A |
probably damaging |
Het |
| Pdzph1 |
C |
T |
17: 59,239,440 (GRCm39) |
A963T |
probably damaging |
Het |
| Pkd1l1 |
C |
T |
11: 8,866,302 (GRCm39) |
V518M |
probably damaging |
Het |
| Plcd3 |
A |
G |
11: 102,969,199 (GRCm39) |
F256S |
probably damaging |
Het |
| Proc |
T |
C |
18: 32,266,491 (GRCm39) |
D112G |
possibly damaging |
Het |
| Ptges2 |
T |
A |
2: 32,290,874 (GRCm39) |
|
probably null |
Het |
| Pth2r |
A |
T |
1: 65,402,436 (GRCm39) |
R312W |
probably damaging |
Het |
| Pttg1ip2 |
C |
A |
5: 5,502,073 (GRCm39) |
|
probably benign |
Het |
| Rbbp6 |
C |
T |
7: 122,591,676 (GRCm39) |
H546Y |
possibly damaging |
Het |
| Retreg2 |
A |
G |
1: 75,123,164 (GRCm39) |
E364G |
probably damaging |
Het |
| Rxrb |
G |
A |
17: 34,253,134 (GRCm39) |
C185Y |
probably damaging |
Het |
| Septin2 |
T |
A |
1: 93,427,037 (GRCm39) |
N133K |
possibly damaging |
Het |
| Serpina3b |
T |
A |
12: 104,104,969 (GRCm39) |
S382T |
probably benign |
Het |
| Serpinb9e |
T |
C |
13: 33,439,099 (GRCm39) |
F175S |
probably benign |
Het |
| Slc19a2 |
C |
T |
1: 164,084,766 (GRCm39) |
H219Y |
probably damaging |
Het |
| Slfn9 |
A |
T |
11: 82,872,524 (GRCm39) |
D737E |
possibly damaging |
Het |
| Snx31 |
T |
C |
15: 36,539,444 (GRCm39) |
E144G |
probably null |
Het |
| Sp2 |
A |
G |
11: 96,854,282 (GRCm39) |
|
probably benign |
Het |
| Spag9 |
C |
T |
11: 94,007,663 (GRCm39) |
L1117F |
probably damaging |
Het |
| Spata31e2 |
G |
T |
1: 26,721,222 (GRCm39) |
Y1319* |
probably null |
Het |
| Syndig1l |
A |
T |
12: 84,727,137 (GRCm39) |
|
probably benign |
Het |
| Sypl1 |
A |
T |
12: 33,024,332 (GRCm39) |
|
probably benign |
Het |
| Tmem169 |
T |
C |
1: 72,339,855 (GRCm39) |
M95T |
probably benign |
Het |
| Tnfrsf17 |
A |
G |
16: 11,133,066 (GRCm39) |
Y48C |
possibly damaging |
Het |
| Ttn |
A |
T |
2: 76,657,859 (GRCm39) |
|
probably benign |
Het |
| Uap1 |
G |
C |
1: 169,977,952 (GRCm39) |
H366Q |
probably benign |
Het |
| Ulbp1 |
A |
G |
10: 7,396,557 (GRCm39) |
|
probably benign |
Het |
| Urb2 |
T |
C |
8: 124,757,647 (GRCm39) |
V1118A |
probably benign |
Het |
| Usp54 |
T |
C |
14: 20,600,258 (GRCm39) |
N1493S |
probably benign |
Het |
| Vmn1r129 |
C |
A |
7: 21,094,655 (GRCm39) |
V188F |
probably benign |
Het |
| Vmn1r226 |
A |
T |
17: 20,907,994 (GRCm39) |
L75F |
probably benign |
Het |
| Yes1 |
T |
A |
5: 32,809,046 (GRCm39) |
S137R |
probably benign |
Het |
| Zfp804b |
A |
G |
5: 7,229,372 (GRCm39) |
|
probably benign |
Het |
|
| Other mutations in Ly75 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00561:Ly75
|
APN |
2 |
60,206,421 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01072:Ly75
|
APN |
2 |
60,184,840 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01409:Ly75
|
APN |
2 |
60,152,036 (GRCm39) |
splice site |
probably null |
|
|
IGL01432:Ly75
|
APN |
2 |
60,206,351 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01626:Ly75
|
APN |
2 |
60,131,359 (GRCm39) |
missense |
probably benign |
0.13 |
|
IGL01690:Ly75
|
APN |
2 |
60,168,655 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01862:Ly75
|
APN |
2 |
60,129,516 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01982:Ly75
|
APN |
2 |
60,142,108 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02075:Ly75
|
APN |
2 |
60,182,700 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02338:Ly75
|
APN |
2 |
60,184,796 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL02364:Ly75
|
APN |
2 |
60,188,851 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02456:Ly75
|
APN |
2 |
60,124,125 (GRCm39) |
missense |
probably benign |
0.09 |
|
IGL02474:Ly75
|
APN |
2 |
60,213,526 (GRCm39) |
missense |
probably null |
1.00 |
|
IGL02608:Ly75
|
APN |
2 |
60,152,244 (GRCm39) |
missense |
probably benign |
0.41 |
|
IGL02986:Ly75
|
APN |
2 |
60,138,535 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03015:Ly75
|
APN |
2 |
60,206,504 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03049:Ly75
|
APN |
2 |
60,182,414 (GRCm39) |
missense |
probably damaging |
0.99 |
|
euphues
|
UTSW |
2 |
60,129,389 (GRCm39) |
critical splice donor site |
probably null |
|
|
four_score
|
UTSW |
2 |
60,142,115 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
lyly
|
UTSW |
2 |
60,158,217 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
Witty
|
UTSW |
2 |
60,184,844 (GRCm39) |
missense |
probably damaging |
1.00 |
|
D605:Ly75
|
UTSW |
2 |
60,182,696 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0046:Ly75
|
UTSW |
2 |
60,169,801 (GRCm39) |
intron |
probably benign |
|
|
R0055:Ly75
|
UTSW |
2 |
60,152,262 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0055:Ly75
|
UTSW |
2 |
60,152,262 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0071:Ly75
|
UTSW |
2 |
60,152,163 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0071:Ly75
|
UTSW |
2 |
60,152,163 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0285:Ly75
|
UTSW |
2 |
60,148,663 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0387:Ly75
|
UTSW |
2 |
60,136,748 (GRCm39) |
missense |
probably benign |
0.20 |
|
R0492:Ly75
|
UTSW |
2 |
60,138,620 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0688:Ly75
|
UTSW |
2 |
60,146,565 (GRCm39) |
missense |
probably benign |
0.41 |
|
R1367:Ly75
|
UTSW |
2 |
60,124,102 (GRCm39) |
splice site |
probably null |
|
|
R1581:Ly75
|
UTSW |
2 |
60,158,237 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1663:Ly75
|
UTSW |
2 |
60,144,578 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1818:Ly75
|
UTSW |
2 |
60,142,121 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1881:Ly75
|
UTSW |
2 |
60,180,284 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2244:Ly75
|
UTSW |
2 |
60,180,257 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2905:Ly75
|
UTSW |
2 |
60,164,898 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3967:Ly75
|
UTSW |
2 |
60,158,217 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R3968:Ly75
|
UTSW |
2 |
60,158,217 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R4039:Ly75
|
UTSW |
2 |
60,183,339 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4406:Ly75
|
UTSW |
2 |
60,184,894 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4526:Ly75
|
UTSW |
2 |
60,161,117 (GRCm39) |
missense |
probably benign |
0.09 |
|
R4647:Ly75
|
UTSW |
2 |
60,138,622 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4795:Ly75
|
UTSW |
2 |
60,180,284 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4796:Ly75
|
UTSW |
2 |
60,180,284 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4962:Ly75
|
UTSW |
2 |
60,182,469 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4979:Ly75
|
UTSW |
2 |
60,206,238 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5072:Ly75
|
UTSW |
2 |
60,206,307 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5288:Ly75
|
UTSW |
2 |
60,133,985 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5373:Ly75
|
UTSW |
2 |
60,142,115 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R5374:Ly75
|
UTSW |
2 |
60,142,115 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R5384:Ly75
|
UTSW |
2 |
60,164,831 (GRCm39) |
nonsense |
probably null |
|
|
R5385:Ly75
|
UTSW |
2 |
60,133,985 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5395:Ly75
|
UTSW |
2 |
60,195,455 (GRCm39) |
missense |
probably benign |
0.41 |
|
R5531:Ly75
|
UTSW |
2 |
60,195,489 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5662:Ly75
|
UTSW |
2 |
60,182,725 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5667:Ly75
|
UTSW |
2 |
60,138,655 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5668:Ly75
|
UTSW |
2 |
60,184,844 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5671:Ly75
|
UTSW |
2 |
60,138,655 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5677:Ly75
|
UTSW |
2 |
60,129,426 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5764:Ly75
|
UTSW |
2 |
60,148,783 (GRCm39) |
missense |
probably benign |
|
|
R5896:Ly75
|
UTSW |
2 |
60,213,490 (GRCm39) |
missense |
probably benign |
|
|
R6025:Ly75
|
UTSW |
2 |
60,206,306 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6113:Ly75
|
UTSW |
2 |
60,199,217 (GRCm39) |
missense |
probably benign |
0.04 |
|
R6448:Ly75
|
UTSW |
2 |
60,129,389 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6601:Ly75
|
UTSW |
2 |
60,148,720 (GRCm39) |
missense |
probably benign |
0.11 |
|
R6745:Ly75
|
UTSW |
2 |
60,138,523 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6955:Ly75
|
UTSW |
2 |
60,158,217 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R6960:Ly75
|
UTSW |
2 |
60,136,749 (GRCm39) |
missense |
probably benign |
|
|
R7100:Ly75
|
UTSW |
2 |
60,136,778 (GRCm39) |
missense |
probably benign |
|
|
R7110:Ly75
|
UTSW |
2 |
60,206,528 (GRCm39) |
missense |
probably benign |
0.31 |
|
R7203:Ly75
|
UTSW |
2 |
60,154,196 (GRCm39) |
nonsense |
probably null |
|
|
R7291:Ly75
|
UTSW |
2 |
60,160,337 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7308:Ly75
|
UTSW |
2 |
60,164,859 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7447:Ly75
|
UTSW |
2 |
60,164,818 (GRCm39) |
nonsense |
probably null |
|
|
R7512:Ly75
|
UTSW |
2 |
60,164,907 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7595:Ly75
|
UTSW |
2 |
60,124,171 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7976:Ly75
|
UTSW |
2 |
60,195,432 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8005:Ly75
|
UTSW |
2 |
60,163,278 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8171:Ly75
|
UTSW |
2 |
60,144,572 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R8392:Ly75
|
UTSW |
2 |
60,180,284 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8705:Ly75
|
UTSW |
2 |
60,148,729 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8714:Ly75
|
UTSW |
2 |
60,164,829 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8798:Ly75
|
UTSW |
2 |
60,154,270 (GRCm39) |
missense |
probably benign |
0.32 |
|
R8799:Ly75
|
UTSW |
2 |
60,178,785 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8834:Ly75
|
UTSW |
2 |
60,161,433 (GRCm39) |
missense |
probably benign |
|
|
R8990:Ly75
|
UTSW |
2 |
60,188,903 (GRCm39) |
missense |
probably benign |
0.10 |
|
R9015:Ly75
|
UTSW |
2 |
60,146,442 (GRCm39) |
missense |
probably benign |
|
|
R9547:Ly75
|
UTSW |
2 |
60,161,069 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9628:Ly75
|
UTSW |
2 |
60,158,285 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9659:Ly75
|
UTSW |
2 |
60,168,665 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9660:Ly75
|
UTSW |
2 |
60,154,184 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9747:Ly75
|
UTSW |
2 |
60,136,672 (GRCm39) |
critical splice donor site |
probably null |
|
|
X0025:Ly75
|
UTSW |
2 |
60,184,819 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Ly75
|
UTSW |
2 |
60,182,477 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
Z1177:Ly75
|
UTSW |
2 |
60,180,348 (GRCm39) |
nonsense |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- ATGTAGCTGAGCTTCCCCAATGCC -3'
(R):5'- GAGCAGTCAGTCTCTGTGCTCTTTC -3'
Sequencing Primer
(F):5'- CTTCTTGAGCAGATTCTGAAGGC -3'
(R):5'- CACAGTATATGGCCTGCTCAG -3'
|
| Posted On |
2014-03-14 |
Incidental Mutation