Mutagenetix > Incidental Mutation

Incidental Mutation 'R1419:Gm16380'

159996

Institutional Source

Beutler Lab

Gene Symbol

Gm16380

Ensembl Gene

ENSMUSG00000059830

Gene Name

predicted pseudogene 16380

Synonyms

MMRRC Submission

039475-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.129) question?

Stock #

R1419 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

53791368-53791845 bp(+) (GRCm39)

Type of Mutation

exon

DNA Base Change (assembly)

C to T at 53791471 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Gene Model

predicted gene model for transcript(s):

AlphaFold

no structure available at present

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000077997

SMART Domains

Protein: ENSMUSP00000129245
Gene: ENSMUSG00000059830

Domain	Start	End	E-Value	Type
Pfam:Siva	1	152	6.6e-65	PFAM

Coding Region Coverage

1x: 98.9%
3x: 98.0%
10x: 95.5%
20x: 90.1%

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 40 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abca15	T	A	7: 119,974,125 (GRCm39)	M894K	probably benign	Het
Ablim1	C	A	19: 57,123,065 (GRCm39)	C173F	probably damaging	Het
Abtb2	G	T	2: 103,539,765 (GRCm39)	R710L	probably benign	Het
Arap3	T	C	18: 38,111,485 (GRCm39)	T1144A	possibly damaging	Het
Arhgef12	A	T	9: 42,938,516 (GRCm39)	V92D	probably damaging	Het
Ash1l	T	G	3: 88,892,204 (GRCm39)	M1361R	probably damaging	Het
Atm	A	C	9: 53,368,789 (GRCm39)	N2337K	probably benign	Het
Cog7	T	C	7: 121,555,215 (GRCm39)	E316G	probably damaging	Het
Dsp	A	G	13: 38,370,671 (GRCm39)	Y858C	probably damaging	Het
Enc1	G	T	13: 97,382,692 (GRCm39)	G401C	probably damaging	Het
Gata6	T	C	18: 11,064,706 (GRCm39)	V506A	probably benign	Het
Hsd17b8	G	A	17: 34,246,617 (GRCm39)	R89C	probably benign	Het
Hsh2d	G	A	8: 72,954,304 (GRCm39)	D229N	probably benign	Het
Ift80	T	A	3: 68,847,531 (GRCm39)	N322Y	probably damaging	Het
Igsf9	T	A	1: 172,325,578 (GRCm39)	V1082E	probably damaging	Het
Katnal2	A	T	18: 77,065,128 (GRCm39)	L481Q	possibly damaging	Het
Kcnma1	T	C	14: 23,417,710 (GRCm39)	T713A	probably damaging	Het
Kif13a	T	C	13: 46,978,711 (GRCm39)	T230A	probably damaging	Het
Klhl14	C	A	18: 21,785,250 (GRCm39)	R59L	probably damaging	Het
Mecom	A	G	3: 30,035,038 (GRCm39)	C213R	probably damaging	Het
Mrpl13	T	A	15: 55,397,717 (GRCm39)	M178L	probably benign	Het
Myof	T	C	19: 37,890,359 (GRCm39)	E1971G	probably damaging	Het
Naa10	A	G	X: 72,961,522 (GRCm39)	V133A	probably damaging	Het
Nlrp4g	G	A	9: 124,349,434 (GRCm38)		noncoding transcript	Het
Ofcc1	C	T	13: 40,362,305 (GRCm39)	G206R	probably benign	Het
Oplah	T	C	15: 76,182,120 (GRCm39)	I1047V	probably benign	Het
Or4a15	T	C	2: 89,193,666 (GRCm39)	T36A	probably damaging	Het
Or4k47	A	T	2: 111,451,640 (GRCm39)	F260I	probably benign	Het
Or5al1	A	G	2: 85,989,773 (GRCm39)	*314Q	probably null	Het
Paip1	A	G	13: 119,593,553 (GRCm39)	D189G	probably damaging	Het
Pkn1	A	G	8: 84,400,151 (GRCm39)	F624L	probably damaging	Het
Plxnb1	C	A	9: 108,943,454 (GRCm39)	P1899H	probably damaging	Het
Rpa3	T	A	6: 8,257,720 (GRCm39)	E47D	probably benign	Het
Shoc1	T	C	4: 59,064,457 (GRCm39)	T826A	possibly damaging	Het
Snai2	C	T	16: 14,526,044 (GRCm39)	H232Y	possibly damaging	Het
Spint5	T	C	2: 164,557,331 (GRCm39)	S23P	possibly damaging	Het
St8sia2	G	A	7: 73,616,742 (GRCm39)	Q78*	probably null	Het
Tktl2	A	G	8: 66,965,690 (GRCm39)	N416S	probably damaging	Het
Tm7sf3	T	A	6: 146,505,475 (GRCm39)	I494F	possibly damaging	Het
Trf	C	T	9: 103,103,307 (GRCm39)	V119M	probably damaging	Het

Other mutations in Gm16380

Allele	Source	Chr	Coord	Type	Predicted Effect
IGL02207:Gm16380	APN	9	53,791,823 (GRCm39)	exon	noncoding transcript
R0386:Gm16380	UTSW	9	53,791,727 (GRCm39)	exon	noncoding transcript
R0398:Gm16380	UTSW	9	53,791,453 (GRCm39)	exon	noncoding transcript
R0512:Gm16380	UTSW	9	53,791,529 (GRCm39)	exon	noncoding transcript
R2301:Gm16380	UTSW	9	53,791,484 (GRCm39)	exon	noncoding transcript
R3697:Gm16380	UTSW	9	53,791,736 (GRCm39)	exon	noncoding transcript
R5128:Gm16380	UTSW	9	53,791,397 (GRCm39)	exon	noncoding transcript

Predicted Primers

PCR Primer
(F):5'- ATCTAGTGACGTGTGCTCGGCG -3'
(R):5'- TCCACAGATCTCATGCACGATGAAC -3'

Sequencing Primer
(F):5'- TGTGTGATACCCGCTACCAT -3'
(R):5'- TCATGCACGATGAACAAGCG -3'

Posted On

2014-03-14