Incidental Mutation 'R1436:Pde8b'
| ID |
160663 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Pde8b
|
| Ensembl Gene |
ENSMUSG00000021684 |
| Gene Name |
phosphodiesterase 8B |
| Synonyms |
B230331L10Rik, C030047E14Rik |
| MMRRC Submission |
039491-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.110)
|
| Stock # |
R1436 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
13 |
| Chromosomal Location |
95160962-95386844 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 95162678 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Alanine
at position 815
(T815A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000128987
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000022192]
[ENSMUST00000056512]
[ENSMUST00000067082]
[ENSMUST00000160801]
[ENSMUST00000162153]
[ENSMUST00000162292]
[ENSMUST00000162412]
[ENSMUST00000172104]
|
| AlphaFold |
E9Q4S1 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000022192
AA Change: T823A
PolyPhen 2
Score 0.002 (Sensitivity: 0.99; Specificity: 0.30)
|
| SMART Domains |
Protein: ENSMUSP00000022192
Gene: ENSMUSG00000021684
AA Change: T823A
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:PDE8
|
1 |
52 |
2.2e-39 |
PFAM |
|
low complexity region
|
75 |
98 |
N/A |
INTRINSIC |
|
Pfam:Response_reg
|
134 |
252 |
2.9e-15 |
PFAM |
|
Blast:HDc
|
420 |
481 |
1e-20 |
BLAST |
|
HDc
|
565 |
748 |
3.01e-3 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000056512
|
| SMART Domains |
Protein: ENSMUSP00000055145
Gene: ENSMUSG00000042015
| Domain | Start | End | E-Value | Type |
|---|
|
WD40
|
32 |
70 |
4.48e-2 |
SMART |
|
WD40
|
73 |
119 |
1.24e-4 |
SMART |
|
WD40
|
122 |
159 |
1.28e1 |
SMART |
|
WD40
|
211 |
249 |
2.86e0 |
SMART |
|
WD40
|
308 |
350 |
7.92e-3 |
SMART |
|
WD40
|
394 |
432 |
1.67e-1 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000067082
AA Change: T850A
PolyPhen 2
Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)
|
| SMART Domains |
Protein: ENSMUSP00000070465
Gene: ENSMUSG00000021684
AA Change: T850A
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:PDE8
|
1 |
47 |
1.4e-32 |
PFAM |
|
low complexity region
|
75 |
98 |
N/A |
INTRINSIC |
|
Blast:REC
|
112 |
235 |
6e-45 |
BLAST |
|
PAS
|
249 |
316 |
3.59e-3 |
SMART |
|
Blast:HDc
|
447 |
508 |
1e-20 |
BLAST |
|
HDc
|
592 |
775 |
3.01e-3 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000160801
|
| SMART Domains |
Protein: ENSMUSP00000124033
Gene: ENSMUSG00000042015
| Domain | Start | End | E-Value | Type |
|---|
|
WD40
|
32 |
70 |
4.48e-2 |
SMART |
|
WD40
|
73 |
119 |
1.24e-4 |
SMART |
|
WD40
|
122 |
159 |
1.28e1 |
SMART |
|
WD40
|
211 |
249 |
2.86e0 |
SMART |
|
WD40
|
308 |
350 |
7.92e-3 |
SMART |
|
WD40
|
394 |
432 |
1.67e-1 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000162153
AA Change: T765A
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000124704
Gene: ENSMUSG00000021684
AA Change: T765A
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Response_reg
|
29 |
147 |
2.6e-15 |
PFAM |
|
PAS
|
164 |
231 |
3.59e-3 |
SMART |
|
Blast:HDc
|
362 |
423 |
1e-20 |
BLAST |
|
HDc
|
507 |
690 |
3.01e-3 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000162292
AA Change: T773A
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000124068
Gene: ENSMUSG00000021684
AA Change: T773A
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:PDE8
|
1 |
52 |
2.1e-39 |
PFAM |
|
low complexity region
|
75 |
98 |
N/A |
INTRINSIC |
|
Pfam:Response_reg
|
134 |
252 |
2.6e-15 |
PFAM |
|
Blast:HDc
|
370 |
431 |
1e-20 |
BLAST |
|
HDc
|
515 |
698 |
3.01e-3 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000162412
AA Change: T715A
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000124409
Gene: ENSMUSG00000021684
AA Change: T715A
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Response_reg
|
29 |
147 |
2.3e-15 |
PFAM |
|
PAS
|
164 |
231 |
3.59e-3 |
SMART |
|
Blast:HDc
|
312 |
373 |
1e-20 |
BLAST |
|
HDc
|
457 |
640 |
3.01e-3 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000172104
AA Change: T815A
PolyPhen 2
Score 0.002 (Sensitivity: 0.99; Specificity: 0.30)
|
| SMART Domains |
Protein: ENSMUSP00000128987
Gene: ENSMUSG00000021684
AA Change: T815A
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:PDE8
|
1 |
52 |
2.2e-39 |
PFAM |
|
low complexity region
|
75 |
98 |
N/A |
INTRINSIC |
|
Pfam:Response_reg
|
134 |
252 |
2.8e-15 |
PFAM |
|
PAS
|
269 |
336 |
3.59e-3 |
SMART |
|
HDc
|
557 |
740 |
3.01e-3 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000162882
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000220923
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000162670
|
| SMART Domains |
Protein: ENSMUSP00000125237
Gene: ENSMUSG00000021684
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:PDEase_I
|
1 |
182 |
6.6e-56 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000223486
|
| Meta Mutation Damage Score |
0.1108 |
| Coding Region Coverage |
- 1x: 98.9%
- 3x: 97.8%
- 10x: 94.6%
- 20x: 86.8%
|
| Validation Efficiency |
94% (65/69) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a cyclic nucleotide phosphodiesterase (PDE) that catalyzes the hydrolysis of the second messenger cAMP. The encoded protein, which does not hydrolyze cGMP, is resistant to several PDE inhibitors. Defects in this gene are a cause of autosomal dominant striatal degeneration (ADSD). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2010]
PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased uring corticosterone, decreased serum adrenocorticotropin and decreased sensitivity to a PDE8-selective inhibitor. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 59 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| A2m |
T |
C |
6: 121,621,172 (GRCm39) |
F292S |
probably benign |
Het |
| Aadacl2fm3 |
A |
T |
3: 59,772,760 (GRCm39) |
D88V |
probably damaging |
Het |
| Abca13 |
T |
C |
11: 9,242,646 (GRCm39) |
V1503A |
probably damaging |
Het |
| AI661453 |
C |
T |
17: 47,777,627 (GRCm39) |
|
probably benign |
Het |
| Ano2 |
T |
C |
6: 125,844,134 (GRCm39) |
|
probably null |
Het |
| Areg |
G |
T |
5: 91,287,664 (GRCm39) |
|
probably benign |
Het |
| Atg16l2 |
A |
G |
7: 100,940,757 (GRCm39) |
V453A |
probably damaging |
Het |
| BC034090 |
A |
G |
1: 155,101,662 (GRCm39) |
S563P |
probably benign |
Het |
| Bhmt-ps1 |
A |
G |
4: 26,369,591 (GRCm39) |
|
noncoding transcript |
Het |
| Birc6 |
C |
A |
17: 74,959,700 (GRCm39) |
P3855Q |
probably damaging |
Het |
| Cd151 |
A |
T |
7: 141,049,197 (GRCm39) |
K8M |
probably damaging |
Het |
| Cd163 |
T |
C |
6: 124,304,890 (GRCm39) |
V1089A |
possibly damaging |
Het |
| Chd3 |
A |
T |
11: 69,248,400 (GRCm39) |
|
probably null |
Het |
| Cnot6l |
T |
A |
5: 96,281,971 (GRCm39) |
E9V |
probably damaging |
Het |
| Col22a1 |
A |
G |
15: 71,794,806 (GRCm39) |
|
probably benign |
Het |
| Cyp2c68 |
A |
G |
19: 39,729,484 (GRCm39) |
M1T |
probably null |
Het |
| Dbp |
T |
C |
7: 45,357,879 (GRCm39) |
V149A |
probably damaging |
Het |
| Dnah10 |
T |
C |
5: 124,839,285 (GRCm39) |
V1241A |
probably benign |
Het |
| Galnt10 |
T |
C |
11: 57,662,295 (GRCm39) |
S314P |
probably damaging |
Het |
| Glce |
C |
T |
9: 61,977,292 (GRCm39) |
|
probably null |
Het |
| Gm5093 |
C |
G |
17: 46,750,680 (GRCm39) |
D116H |
probably damaging |
Het |
| Golim4 |
A |
G |
3: 75,785,951 (GRCm39) |
|
probably null |
Het |
| Helz2 |
A |
T |
2: 180,877,317 (GRCm39) |
I1107N |
probably damaging |
Het |
| Hoxc9 |
T |
C |
15: 102,890,304 (GRCm39) |
S74P |
probably benign |
Het |
| Ikbkb |
T |
A |
8: 23,163,419 (GRCm39) |
N297I |
probably benign |
Het |
| Il20ra |
T |
A |
10: 19,625,000 (GRCm39) |
I93N |
probably damaging |
Het |
| Itch |
C |
A |
2: 155,034,065 (GRCm39) |
N412K |
probably damaging |
Het |
| Kcna5 |
T |
A |
6: 126,511,724 (GRCm39) |
T135S |
probably damaging |
Het |
| Lncpint |
G |
A |
6: 31,157,974 (GRCm39) |
|
noncoding transcript |
Het |
| Lrrc39 |
A |
T |
3: 116,373,293 (GRCm39) |
|
probably null |
Het |
| Mad2l1 |
T |
A |
6: 66,516,797 (GRCm39) |
V163E |
possibly damaging |
Het |
| Moxd1 |
C |
T |
10: 24,120,256 (GRCm39) |
T128M |
probably damaging |
Het |
| Mpeg1 |
C |
T |
19: 12,439,823 (GRCm39) |
S427F |
probably damaging |
Het |
| Nckap5 |
T |
C |
1: 125,953,798 (GRCm39) |
Y854C |
possibly damaging |
Het |
| Ncln |
C |
T |
10: 81,325,727 (GRCm39) |
E373K |
probably damaging |
Het |
| Neurod4 |
T |
C |
10: 130,106,540 (GRCm39) |
T245A |
possibly damaging |
Het |
| Nsun5 |
T |
C |
5: 135,399,067 (GRCm39) |
L39P |
probably damaging |
Het |
| Or2ad1 |
G |
T |
13: 21,327,162 (GRCm39) |
Q22K |
probably benign |
Het |
| Or4c105 |
A |
T |
2: 88,648,336 (GRCm39) |
T274S |
possibly damaging |
Het |
| Or4f7 |
A |
G |
2: 111,644,906 (GRCm39) |
L55S |
probably damaging |
Het |
| Pofut2 |
C |
T |
10: 77,104,398 (GRCm39) |
R392W |
probably damaging |
Het |
| Ppip5k2 |
G |
A |
1: 97,639,507 (GRCm39) |
T1186I |
probably benign |
Het |
| Rhot2 |
A |
C |
17: 26,060,374 (GRCm39) |
S277R |
probably benign |
Het |
| Satb1 |
T |
G |
17: 52,111,391 (GRCm39) |
|
probably null |
Het |
| Sec31b |
T |
C |
19: 44,524,634 (GRCm39) |
I88V |
probably damaging |
Het |
| Selenon |
T |
A |
4: 134,267,997 (GRCm39) |
E483V |
probably damaging |
Het |
| Serpinc1 |
A |
G |
1: 160,820,981 (GRCm39) |
T22A |
possibly damaging |
Het |
| Sf3a2 |
G |
A |
10: 80,640,040 (GRCm39) |
|
probably benign |
Het |
| Sf3b1 |
A |
G |
1: 55,040,580 (GRCm39) |
Y561H |
possibly damaging |
Het |
| Smarcc1 |
T |
A |
9: 109,947,708 (GRCm39) |
|
probably benign |
Het |
| Stard3nl |
C |
T |
13: 19,556,819 (GRCm39) |
R107Q |
probably damaging |
Het |
| Syce1 |
C |
T |
7: 140,357,593 (GRCm39) |
R324H |
possibly damaging |
Het |
| Tnk1 |
G |
T |
11: 69,743,119 (GRCm39) |
|
probably benign |
Het |
| Trim46 |
A |
G |
3: 89,150,968 (GRCm39) |
F198L |
probably damaging |
Het |
| Trip4 |
A |
T |
9: 65,788,233 (GRCm39) |
W71R |
probably damaging |
Het |
| Ubox5 |
A |
C |
2: 130,439,213 (GRCm39) |
|
probably benign |
Het |
| Ust |
G |
A |
10: 8,183,202 (GRCm39) |
T167M |
probably damaging |
Het |
| Zbtb2 |
T |
C |
10: 4,318,697 (GRCm39) |
Q443R |
probably benign |
Het |
| Zfp407 |
A |
G |
18: 84,361,196 (GRCm39) |
|
probably benign |
Het |
|
| Other mutations in Pde8b |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00325:Pde8b
|
APN |
13 |
95,170,875 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01517:Pde8b
|
APN |
13 |
95,237,395 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL01736:Pde8b
|
APN |
13 |
95,166,910 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01756:Pde8b
|
APN |
13 |
95,182,895 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01867:Pde8b
|
APN |
13 |
95,237,446 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01939:Pde8b
|
APN |
13 |
95,232,232 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02026:Pde8b
|
APN |
13 |
95,170,869 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02685:Pde8b
|
APN |
13 |
95,162,628 (GRCm39) |
makesense |
probably null |
|
|
IGL02830:Pde8b
|
APN |
13 |
95,189,409 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL02966:Pde8b
|
APN |
13 |
95,232,156 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL03003:Pde8b
|
APN |
13 |
95,178,465 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03064:Pde8b
|
APN |
13 |
95,182,906 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03349:Pde8b
|
APN |
13 |
95,179,551 (GRCm39) |
splice site |
probably benign |
|
|
R0356:Pde8b
|
UTSW |
13 |
95,182,962 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0464:Pde8b
|
UTSW |
13 |
95,241,206 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0711:Pde8b
|
UTSW |
13 |
95,244,325 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R1467:Pde8b
|
UTSW |
13 |
95,170,680 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1467:Pde8b
|
UTSW |
13 |
95,170,680 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1494:Pde8b
|
UTSW |
13 |
95,184,304 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1546:Pde8b
|
UTSW |
13 |
95,182,951 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1699:Pde8b
|
UTSW |
13 |
95,169,374 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1795:Pde8b
|
UTSW |
13 |
95,178,527 (GRCm39) |
missense |
probably benign |
0.10 |
|
R1879:Pde8b
|
UTSW |
13 |
95,221,723 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R2184:Pde8b
|
UTSW |
13 |
95,162,723 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2223:Pde8b
|
UTSW |
13 |
95,179,955 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2892:Pde8b
|
UTSW |
13 |
95,170,767 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3034:Pde8b
|
UTSW |
13 |
95,359,275 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4204:Pde8b
|
UTSW |
13 |
95,359,053 (GRCm39) |
missense |
probably benign |
0.22 |
|
R4206:Pde8b
|
UTSW |
13 |
95,359,053 (GRCm39) |
missense |
probably benign |
0.22 |
|
R4623:Pde8b
|
UTSW |
13 |
95,178,447 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R4711:Pde8b
|
UTSW |
13 |
95,166,958 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5133:Pde8b
|
UTSW |
13 |
95,223,250 (GRCm39) |
missense |
probably benign |
0.05 |
|
R5134:Pde8b
|
UTSW |
13 |
95,223,250 (GRCm39) |
missense |
probably benign |
0.05 |
|
R5314:Pde8b
|
UTSW |
13 |
95,223,361 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R5342:Pde8b
|
UTSW |
13 |
95,178,498 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5376:Pde8b
|
UTSW |
13 |
95,162,654 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5806:Pde8b
|
UTSW |
13 |
95,178,548 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5830:Pde8b
|
UTSW |
13 |
95,178,398 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6021:Pde8b
|
UTSW |
13 |
95,162,670 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R6035:Pde8b
|
UTSW |
13 |
95,164,105 (GRCm39) |
intron |
probably benign |
|
|
R6035:Pde8b
|
UTSW |
13 |
95,164,105 (GRCm39) |
intron |
probably benign |
|
|
R6129:Pde8b
|
UTSW |
13 |
95,178,467 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6181:Pde8b
|
UTSW |
13 |
95,223,316 (GRCm39) |
missense |
probably benign |
0.36 |
|
R6313:Pde8b
|
UTSW |
13 |
95,178,508 (GRCm39) |
nonsense |
probably null |
|
|
R6849:Pde8b
|
UTSW |
13 |
95,184,307 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R6914:Pde8b
|
UTSW |
13 |
95,223,352 (GRCm39) |
missense |
probably benign |
0.06 |
|
R6999:Pde8b
|
UTSW |
13 |
95,223,342 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R7149:Pde8b
|
UTSW |
13 |
95,223,349 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7275:Pde8b
|
UTSW |
13 |
95,179,442 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7483:Pde8b
|
UTSW |
13 |
95,164,251 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7553:Pde8b
|
UTSW |
13 |
95,223,258 (GRCm39) |
missense |
probably benign |
0.21 |
|
R7790:Pde8b
|
UTSW |
13 |
95,170,679 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7802:Pde8b
|
UTSW |
13 |
95,237,446 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7852:Pde8b
|
UTSW |
13 |
95,244,205 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7872:Pde8b
|
UTSW |
13 |
95,223,347 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R7897:Pde8b
|
UTSW |
13 |
95,244,202 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8144:Pde8b
|
UTSW |
13 |
95,359,278 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8792:Pde8b
|
UTSW |
13 |
95,179,534 (GRCm39) |
missense |
probably benign |
|
|
R8850:Pde8b
|
UTSW |
13 |
95,226,793 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8905:Pde8b
|
UTSW |
13 |
95,182,993 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9252:Pde8b
|
UTSW |
13 |
95,169,424 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9256:Pde8b
|
UTSW |
13 |
95,164,204 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9582:Pde8b
|
UTSW |
13 |
95,169,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TTACAAGGGCACGCAGGCTAAC -3'
(R):5'- GGATACACATGCACACAGATGCCAG -3'
Sequencing Primer
(F):5'- AGGCAGCTCGTTTTGTCAC -3'
(R):5'- tctgtcccctagagctgag -3'
|
| Posted On |
2014-03-14 |
Incidental Mutation