Mutagenetix > Incidental Mutation

Incidental Mutation 'R0097:Gm9938'

16239

Institutional Source

Beutler Lab

Gene Symbol

Gm9938

Ensembl Gene

ENSMUSG00000054178

Gene Name

predicted gene 9938

Synonyms

MMRRC Submission

038383-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.183) question?

Stock #

R0097 (G1)

Quality Score

Status

Validated

Chromosome

Chromosomal Location

23700643-23702398 bp(+) (GRCm39)

Type of Mutation

unclassified

DNA Base Change (assembly)

T to A at 23701828 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000097156 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000067077] [ENSMUST00000099560]

AlphaFold

no structure available at present

Predicted Effect

unknown
Transcript: ENSMUST00000067077
AA Change: N55K

Predicted Effect

probably benign
Transcript: ENSMUST00000099560

SMART Domains

Protein: ENSMUSP00000097156
Gene: ENSMUSG00000074925

Domain	Start	End	E-Value	Type
Pfam:PPTA	122	149	3.9e-8	PFAM
Pfam:PPTA	180	207	5e-11	PFAM
Pfam:PPTA	290	315	8e-9	PFAM

Meta Mutation Damage Score

0.0898

Coding Region Coverage

1x: 89.4%
3x: 86.4%
10x: 78.0%
20x: 64.9%

Validation Efficiency

86% (56/65)

Allele List at MGI

Other mutations in this stock

Total: 36 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1700006A11Rik	A	T	3: 124,206,129 (GRCm39)	I353K	probably benign	Het
Albfm1	T	A	5: 90,732,795 (GRCm39)	S535R	probably benign	Het
Arfgap2	T	A	2: 91,105,160 (GRCm39)	V422E	probably benign	Het
Baz1b	T	C	5: 135,227,113 (GRCm39)	S105P	probably benign	Het
Cacna1s	T	A	1: 136,028,360 (GRCm39)	M899K	possibly damaging	Het
Ccnd2	G	A	6: 127,123,015 (GRCm39)	A180V	probably benign	Het
Ciao3	T	C	17: 25,995,976 (GRCm39)	S67P	possibly damaging	Het
Dmrta1	A	T	4: 89,577,109 (GRCm39)	R188S	probably benign	Het
Eml3	T	A	19: 8,914,015 (GRCm39)	F465L	probably benign	Het
Gpr87	G	A	3: 59,086,506 (GRCm39)	T333I	probably damaging	Het
Lzic	A	G	4: 149,572,533 (GRCm39)	E41G	probably damaging	Het
Mprip	T	A	11: 59,649,317 (GRCm39)	L1007Q	possibly damaging	Het
Mtfr2	T	A	10: 20,224,122 (GRCm39)	S19T	probably damaging	Het
Mycbp2	A	T	14: 103,393,198 (GRCm39)	M3121K	probably damaging	Het
Myocd	T	A	11: 65,069,840 (GRCm39)	M667L	possibly damaging	Het
Neb	T	C	2: 52,094,906 (GRCm39)	N4882S	probably damaging	Het
Neo1	T	C	9: 58,882,021 (GRCm38)		probably benign	Het
Neu2	A	G	1: 87,525,188 (GRCm39)	D391G	probably benign	Het
Nol4	C	A	18: 22,852,198 (GRCm39)	A456S	probably benign	Het
Or5m13	T	C	2: 85,749,184 (GRCm39)	V305A	probably benign	Het
Padi6	C	T	4: 140,458,268 (GRCm39)	V513M	probably benign	Het
Prss38	A	G	11: 59,266,434 (GRCm39)	L8S	possibly damaging	Het
Rab5b	A	T	10: 128,518,809 (GRCm39)	F108I	probably damaging	Het
Ryr3	T	C	2: 112,630,400 (GRCm39)	D2157G	probably damaging	Het
Secisbp2l	T	C	2: 125,613,376 (GRCm39)	D206G	probably damaging	Het
Sh3pxd2b	T	A	11: 32,353,978 (GRCm39)	I182N	probably damaging	Het
Slc3a1	A	T	17: 85,340,288 (GRCm39)	I237F	probably damaging	Het
St6galnac6	T	C	2: 32,489,814 (GRCm39)	L8P	probably damaging	Het
T	A	T	17: 8,658,733 (GRCm39)		probably benign	Het
Tenm4	A	T	7: 96,542,133 (GRCm39)	D1882V	probably damaging	Het
Tgfbr1	T	A	4: 47,403,451 (GRCm39)	L283*	probably null	Het
Ubp1	T	C	9: 113,802,575 (GRCm39)		probably benign	Het
Ushbp1	C	T	8: 71,843,357 (GRCm39)	C314Y	probably damaging	Het
Vav2	A	T	2: 27,189,374 (GRCm39)		probably benign	Het
Vmn1r228	T	C	17: 20,996,625 (GRCm39)	M298V	probably benign	Het
Zmpste24	A	T	4: 120,952,740 (GRCm39)		probably benign	Het

Other mutations in Gm9938

Allele	Source	Chr	Coord	Type	Predicted Effect
R0078:Gm9938	UTSW	19	23,701,988 (GRCm39)	unclassified	probably benign
R0097:Gm9938	UTSW	19	23,701,828 (GRCm39)	unclassified	probably benign
R0990:Gm9938	UTSW	19	23,701,956 (GRCm39)	unclassified	probably benign
R1892:Gm9938	UTSW	19	23,701,955 (GRCm39)	unclassified	probably benign
R7056:Gm9938	UTSW	19	23,701,981 (GRCm39)	unclassified	probably benign
R8845:Gm9938	UTSW	19	23,701,941 (GRCm39)	missense	unknown

Posted On

2013-01-20