Mutagenetix > Incidental Mutation

Incidental Mutation 'R1395:Map1a'

162784

Institutional Source

Beutler Lab

Gene Symbol

Map1a

Ensembl Gene

ENSMUSG00000027254

Gene Name

microtubule-associated protein 1 A

Synonyms

Mtap1a, Mtap-1, 6330416M19Rik, Mtap1

MMRRC Submission

039457-MU

Accession Numbers

Essential gene?

Possibly non essential (E-score: 0.269) question?

Stock #

R1395 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

121120081-121141313 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

C to T at 121134406 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Histidine to Tyrosine at position 1741 (H1741Y)

Ref Sequence

ENSEMBL: ENSMUSP00000092223 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000094639] [ENSMUST00000110639]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000094639
AA Change: H1741Y

PolyPhen 2 Score 0.264 (Sensitivity: 0.91; Specificity: 0.88)

SMART Domains

Protein: ENSMUSP00000092223
Gene: ENSMUSG00000027254
AA Change: H1741Y

Domain	Start	End	E-Value	Type
Blast:Lactamase_B	286	538	2e-54	BLAST
SCOP:d1eq1a_	584	699	8e-5	SMART
low complexity region	743	755	N/A	INTRINSIC
low complexity region	820	833	N/A	INTRINSIC
low complexity region	852	867	N/A	INTRINSIC
low complexity region	897	911	N/A	INTRINSIC
low complexity region	1228	1239	N/A	INTRINSIC
low complexity region	1334	1344	N/A	INTRINSIC
low complexity region	1540	1555	N/A	INTRINSIC
coiled coil region	1573	1602	N/A	INTRINSIC
internal_repeat_1	1616	1726	7.66e-6	PROSPERO
coiled coil region	1747	1771	N/A	INTRINSIC
internal_repeat_1	1774	1888	7.66e-6	PROSPERO
low complexity region	2060	2084	N/A	INTRINSIC
low complexity region	2121	2133	N/A	INTRINSIC
low complexity region	2156	2169	N/A	INTRINSIC
low complexity region	2383	2396	N/A	INTRINSIC
low complexity region	2436	2460	N/A	INTRINSIC
low complexity region	2517	2541	N/A	INTRINSIC
low complexity region	2589	2600	N/A	INTRINSIC
low complexity region	2662	2682	N/A	INTRINSIC
low complexity region	2685	2704	N/A	INTRINSIC
low complexity region	2716	2728	N/A	INTRINSIC
low complexity region	2766	2790	N/A	INTRINSIC
low complexity region	2980	2988	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000110639
AA Change: H1503Y

PolyPhen 2 Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)

SMART Domains

Protein: ENSMUSP00000106269
Gene: ENSMUSG00000027254
AA Change: H1503Y

Domain	Start	End	E-Value	Type
Blast:Lactamase_B	48	300	3e-54	BLAST
SCOP:d1eq1a_	346	461	1e-4	SMART
low complexity region	505	517	N/A	INTRINSIC
low complexity region	582	595	N/A	INTRINSIC
low complexity region	614	629	N/A	INTRINSIC
low complexity region	659	673	N/A	INTRINSIC
low complexity region	990	1001	N/A	INTRINSIC
low complexity region	1096	1106	N/A	INTRINSIC
low complexity region	1302	1317	N/A	INTRINSIC
coiled coil region	1335	1364	N/A	INTRINSIC
internal_repeat_1	1378	1488	5.43e-6	PROSPERO
coiled coil region	1509	1533	N/A	INTRINSIC
internal_repeat_1	1536	1650	5.43e-6	PROSPERO
low complexity region	1822	1846	N/A	INTRINSIC
low complexity region	1883	1895	N/A	INTRINSIC
low complexity region	1918	1931	N/A	INTRINSIC
low complexity region	2145	2158	N/A	INTRINSIC
low complexity region	2198	2222	N/A	INTRINSIC
low complexity region	2279	2303	N/A	INTRINSIC
low complexity region	2351	2362	N/A	INTRINSIC
low complexity region	2424	2444	N/A	INTRINSIC
low complexity region	2447	2466	N/A	INTRINSIC
low complexity region	2478	2490	N/A	INTRINSIC
low complexity region	2528	2552	N/A	INTRINSIC
low complexity region	2742	2750	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000133283

Meta Mutation Damage Score

0.0898

Coding Region Coverage

1x: 99.0%
3x: 98.2%
10x: 96.0%
20x: 92.0%

Validation Efficiency

99% (70/71)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The product of this gene is a precursor polypeptide that presumably undergoes proteolytic processing to generate the final MAP1A heavy chain and LC2 light chain. Expression of this gene is almost exclusively in the brain. Studies of the rat microtubule-associated protein 1A gene suggested a role in early events of spinal cord development. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mice homozygous for a knock-out allele exhibit Purkinje cell degeneration. Mice homozygous for a spontaneous mutation exhibit mild ataxia and Purkinje cell degeneration. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 65 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
2900026A02Rik	A	G	5: 113,249,362 (GRCm39)	Y122H	probably damaging	Het
A330070K13Rik	A	G	5: 130,407,982 (GRCm39)		probably benign	Het
Abcc2	A	G	19: 43,822,379 (GRCm39)	R1406G	probably benign	Het
Adgrv1	G	T	13: 81,534,907 (GRCm39)	T5786K	probably benign	Het
Ankrd27	T	C	7: 35,315,294 (GRCm39)	F481S	possibly damaging	Het
Arhgap11a	C	T	2: 113,663,467 (GRCm39)	V939I	probably benign	Het
Arhgap12	T	C	18: 6,037,058 (GRCm39)	N561S	probably benign	Het
Arhgef12	T	C	9: 42,917,166 (GRCm39)	H391R	probably damaging	Het
Asb3	T	C	11: 31,051,032 (GRCm39)		probably benign	Het
C2cd5	T	C	6: 143,007,464 (GRCm39)		probably benign	Het
Ccdc85a	T	C	11: 28,533,412 (GRCm39)	K44R	possibly damaging	Het
Cep128	C	T	12: 91,233,754 (GRCm39)	R438Q	probably benign	Het
Cep192	A	G	18: 67,991,992 (GRCm39)	T1957A	probably damaging	Het
Col20a1	T	A	2: 180,640,400 (GRCm39)	V519E	probably damaging	Het
Cylc2	A	G	4: 51,228,366 (GRCm39)	K146E	possibly damaging	Het
Drgx	C	T	14: 32,330,326 (GRCm39)	P148S	probably benign	Het
Dst	T	C	1: 34,204,236 (GRCm39)		probably null	Het
Eef1a1	C	T	9: 78,386,300 (GRCm39)	V402I	probably benign	Het
Esyt3	T	C	9: 99,198,835 (GRCm39)		probably benign	Het
Extl3	A	G	14: 65,314,945 (GRCm39)	V79A	possibly damaging	Het
Fat3	C	T	9: 16,158,212 (GRCm39)	V1133I	probably benign	Het
Fcgbp	A	G	7: 27,792,804 (GRCm39)	H936R	probably damaging	Het
Fdxacb1	TAGAC	T	9: 50,683,796 (GRCm39)		probably null	Het
Fryl	T	C	5: 73,230,255 (GRCm39)	H1634R	probably damaging	Het
Gm44511	G	A	6: 128,797,293 (GRCm39)	S32L	possibly damaging	Het
Gm8374	G	T	14: 18,537,058 (GRCm39)	N55K	probably benign	Het
Gria1	T	A	11: 57,174,392 (GRCm39)	I558N	probably damaging	Het
Gse1	G	T	8: 121,301,738 (GRCm39)		probably benign	Het
Gtf3c3	C	T	1: 54,456,937 (GRCm39)	A488T	probably damaging	Het
Hectd4	T	C	5: 121,466,576 (GRCm39)		probably null	Het
Herc1	T	C	9: 66,346,463 (GRCm39)	I1943T	probably benign	Het
Ift172	T	C	5: 31,442,582 (GRCm39)		probably benign	Het
Ift81	G	T	5: 122,706,986 (GRCm39)	D485E	probably benign	Het
Lactb	T	C	9: 66,878,661 (GRCm39)		probably benign	Het
Map1lc3b	T	C	8: 122,323,459 (GRCm39)	Y110H	probably benign	Het
Mlh1	T	C	9: 111,076,445 (GRCm39)	D304G	probably damaging	Het
Myo1f	A	G	17: 33,802,714 (GRCm39)	D386G	probably damaging	Het
Ncoa4	T	A	14: 31,894,798 (GRCm39)		probably null	Het
Neto1	T	C	18: 86,416,144 (GRCm39)		probably benign	Het
Nf1	T	C	11: 79,426,809 (GRCm39)	V1741A	possibly damaging	Het
Nkain2	C	A	10: 32,766,185 (GRCm39)		probably benign	Het
Obsl1	T	C	1: 75,469,309 (GRCm39)	S109G	probably damaging	Het
Or51ah3	T	C	7: 103,210,326 (GRCm39)	L214P	possibly damaging	Het
Or51f23	G	A	7: 102,453,414 (GRCm39)	C243Y	possibly damaging	Het
Or6z6	T	A	7: 6,491,361 (GRCm39)	T171S	probably damaging	Het
Or9s13	T	A	1: 92,548,267 (GRCm39)	I213N	probably benign	Het
Phlpp1	T	C	1: 106,278,348 (GRCm39)	V920A	possibly damaging	Het
Psen1	G	A	12: 83,771,346 (GRCm39)	G209R	probably damaging	Het
Ralgapa2	T	G	2: 146,230,420 (GRCm39)	K963N	probably damaging	Het
Rdh12	A	G	12: 79,255,839 (GRCm39)	T9A	probably benign	Het
Rgma	G	T	7: 73,067,542 (GRCm39)	A360S	probably benign	Het
Sag	G	A	1: 87,756,163 (GRCm39)	V257I	probably benign	Het
Scaf1	T	C	7: 44,657,721 (GRCm39)	E386G	probably damaging	Het
Slc4a10	A	G	2: 62,143,630 (GRCm39)	E1055G	probably benign	Het
Sned1	G	A	1: 93,209,376 (GRCm39)	V830M	possibly damaging	Het
Spata31e5	T	C	1: 28,815,890 (GRCm39)	E714G	possibly damaging	Het
Spata46	A	G	1: 170,139,573 (GRCm39)	T191A	probably benign	Het
Tgm2	T	A	2: 157,966,172 (GRCm39)	H494L	probably benign	Het
Tub	C	T	7: 108,620,161 (GRCm39)	R102*	probably null	Het
Ugt3a1	T	G	15: 9,306,378 (GRCm39)	L176V	possibly damaging	Het
Vmn2r15	T	A	5: 109,442,014 (GRCm39)	I140L	probably benign	Het
Wdr44	T	G	X: 23,662,298 (GRCm39)	C645G	probably damaging	Het
Wdr87-ps	T	A	7: 29,230,812 (GRCm39)		noncoding transcript	Het
Zfp322a	C	T	13: 23,540,945 (GRCm39)	V266I	probably benign	Het
Zfp663	T	C	2: 165,194,492 (GRCm39)	R576G	probably damaging	Het

Other mutations in Map1a

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00419:Map1a	APN	2	121,129,508 (GRCm39)	missense	probably damaging	0.99
IGL00826:Map1a	APN	2	121,132,757 (GRCm39)	missense	possibly damaging	0.87
IGL01476:Map1a	APN	2	121,135,688 (GRCm39)	missense	probably damaging	1.00
IGL02029:Map1a	APN	2	121,133,779 (GRCm39)	missense	possibly damaging	0.57
IGL02100:Map1a	APN	2	121,133,327 (GRCm39)	missense	probably damaging	0.99
IGL02136:Map1a	APN	2	121,130,693 (GRCm39)	missense	probably damaging	1.00
IGL02146:Map1a	APN	2	121,129,927 (GRCm39)	missense	probably damaging	1.00
IGL02264:Map1a	APN	2	121,137,794 (GRCm39)	missense	probably damaging	1.00
IGL02456:Map1a	APN	2	121,129,134 (GRCm39)	missense	probably damaging	1.00
IGL02485:Map1a	APN	2	121,129,769 (GRCm39)	missense	probably damaging	1.00
IGL02535:Map1a	APN	2	121,132,658 (GRCm39)	nonsense	probably null
IGL02628:Map1a	APN	2	121,130,585 (GRCm39)	missense	probably damaging	1.00
IGL02721:Map1a	APN	2	121,134,518 (GRCm39)	missense	probably benign	0.44
IGL03273:Map1a	APN	2	121,130,719 (GRCm39)	missense	probably damaging	1.00
IGL03281:Map1a	APN	2	121,135,541 (GRCm39)	missense	probably damaging	1.00
IGL02991:Map1a	UTSW	2	121,132,091 (GRCm39)	missense	probably damaging	0.99
R0096:Map1a	UTSW	2	121,131,986 (GRCm39)	missense	probably damaging	1.00
R0096:Map1a	UTSW	2	121,131,986 (GRCm39)	missense	probably damaging	1.00
R0218:Map1a	UTSW	2	121,135,906 (GRCm39)	missense	probably benign	0.00
R0363:Map1a	UTSW	2	121,132,525 (GRCm39)	missense	probably damaging	1.00
R0450:Map1a	UTSW	2	121,136,255 (GRCm39)	missense	probably benign	0.27
R0469:Map1a	UTSW	2	121,136,255 (GRCm39)	missense	probably benign	0.27
R0477:Map1a	UTSW	2	121,132,582 (GRCm39)	missense	probably damaging	1.00
R0504:Map1a	UTSW	2	121,133,422 (GRCm39)	missense	probably benign	0.03
R0510:Map1a	UTSW	2	121,136,255 (GRCm39)	missense	probably benign	0.27
R0521:Map1a	UTSW	2	121,136,234 (GRCm39)	missense	probably damaging	1.00
R0601:Map1a	UTSW	2	121,129,083 (GRCm39)	missense	probably damaging	1.00
R0619:Map1a	UTSW	2	121,135,736 (GRCm39)	missense	probably damaging	0.96
R0633:Map1a	UTSW	2	121,138,495 (GRCm39)	missense	probably damaging	1.00
R0652:Map1a	UTSW	2	121,133,264 (GRCm39)	missense	probably benign	0.04
R0893:Map1a	UTSW	2	121,131,014 (GRCm39)	missense	probably damaging	1.00
R0960:Map1a	UTSW	2	121,132,124 (GRCm39)	missense	probably benign	0.16
R1115:Map1a	UTSW	2	121,137,859 (GRCm39)	splice site	probably null
R1166:Map1a	UTSW	2	121,130,741 (GRCm39)	missense	probably damaging	1.00
R1326:Map1a	UTSW	2	121,136,671 (GRCm39)	nonsense	probably null
R1331:Map1a	UTSW	2	121,136,701 (GRCm39)	nonsense	probably null
R1489:Map1a	UTSW	2	121,130,918 (GRCm39)	missense	possibly damaging	0.91
R1573:Map1a	UTSW	2	121,134,607 (GRCm39)	missense	probably benign	0.37
R1596:Map1a	UTSW	2	121,120,246 (GRCm39)	missense	probably benign	0.00
R1662:Map1a	UTSW	2	121,136,889 (GRCm39)	missense	possibly damaging	0.90
R1675:Map1a	UTSW	2	121,133,136 (GRCm39)	nonsense	probably null
R1919:Map1a	UTSW	2	121,137,493 (GRCm39)	missense	probably damaging	1.00
R2122:Map1a	UTSW	2	121,129,927 (GRCm39)	missense	probably damaging	1.00
R2126:Map1a	UTSW	2	121,129,122 (GRCm39)	missense	probably damaging	0.96
R2143:Map1a	UTSW	2	121,132,426 (GRCm39)	missense	probably damaging	1.00
R2172:Map1a	UTSW	2	121,138,413 (GRCm39)	missense	probably damaging	1.00
R2249:Map1a	UTSW	2	121,130,768 (GRCm39)	missense	probably damaging	1.00
R2254:Map1a	UTSW	2	121,134,272 (GRCm39)	missense	possibly damaging	0.71
R2255:Map1a	UTSW	2	121,134,272 (GRCm39)	missense	possibly damaging	0.71
R3834:Map1a	UTSW	2	121,137,803 (GRCm39)	missense	probably damaging	1.00
R4011:Map1a	UTSW	2	121,130,608 (GRCm39)	missense	probably damaging	1.00
R4346:Map1a	UTSW	2	121,131,806 (GRCm39)	missense	probably benign	0.13
R4842:Map1a	UTSW	2	121,132,567 (GRCm39)	missense	probably damaging	1.00
R4933:Map1a	UTSW	2	121,136,386 (GRCm39)	missense	probably damaging	1.00
R4978:Map1a	UTSW	2	121,131,623 (GRCm39)	missense	probably benign	0.00
R4988:Map1a	UTSW	2	121,133,531 (GRCm39)	missense	probably benign	0.34
R5026:Map1a	UTSW	2	121,138,019 (GRCm39)	missense	possibly damaging	0.83
R5086:Map1a	UTSW	2	121,134,985 (GRCm39)	missense	probably damaging	1.00
R5155:Map1a	UTSW	2	121,132,867 (GRCm39)	missense	probably damaging	1.00
R5232:Map1a	UTSW	2	121,132,466 (GRCm39)	missense	probably damaging	1.00
R5311:Map1a	UTSW	2	121,132,868 (GRCm39)	missense	probably damaging	1.00
R5401:Map1a	UTSW	2	121,130,153 (GRCm39)	missense	probably damaging	1.00
R5465:Map1a	UTSW	2	121,136,506 (GRCm39)	missense	probably damaging	1.00
R5526:Map1a	UTSW	2	121,136,143 (GRCm39)	missense	probably damaging	1.00
R5642:Map1a	UTSW	2	121,136,524 (GRCm39)	missense	probably damaging	1.00
R5726:Map1a	UTSW	2	121,135,546 (GRCm39)	missense	probably damaging	1.00
R5817:Map1a	UTSW	2	121,129,391 (GRCm39)	missense	possibly damaging	0.81
R5855:Map1a	UTSW	2	121,134,155 (GRCm39)	missense	possibly damaging	0.74
R5917:Map1a	UTSW	2	121,135,697 (GRCm39)	missense	probably damaging	1.00
R5974:Map1a	UTSW	2	121,134,857 (GRCm39)	missense	probably benign	0.20
R5987:Map1a	UTSW	2	121,134,776 (GRCm39)	missense	possibly damaging	0.56
R6151:Map1a	UTSW	2	121,120,304 (GRCm39)	missense	probably benign	0.12
R6406:Map1a	UTSW	2	121,131,224 (GRCm39)	missense	probably damaging	1.00
R7014:Map1a	UTSW	2	121,130,720 (GRCm39)	missense	probably damaging	1.00
R7099:Map1a	UTSW	2	121,130,998 (GRCm39)	missense	probably benign	0.04
R7211:Map1a	UTSW	2	121,135,124 (GRCm39)	missense	probably benign	0.02
R7230:Map1a	UTSW	2	121,131,299 (GRCm39)	missense	probably damaging	1.00
R7305:Map1a	UTSW	2	121,129,939 (GRCm39)	missense	probably damaging	1.00
R7382:Map1a	UTSW	2	121,121,266 (GRCm39)	missense	probably damaging	1.00
R7524:Map1a	UTSW	2	121,120,293 (GRCm39)	missense	probably damaging	1.00
R7699:Map1a	UTSW	2	121,130,201 (GRCm39)	missense	probably damaging	1.00
R7767:Map1a	UTSW	2	121,132,517 (GRCm39)	missense	probably damaging	1.00
R7883:Map1a	UTSW	2	121,135,853 (GRCm39)	missense	probably damaging	1.00
R7896:Map1a	UTSW	2	121,135,657 (GRCm39)	missense	probably benign	0.00
R7993:Map1a	UTSW	2	121,135,057 (GRCm39)	missense	possibly damaging	0.84
R8270:Map1a	UTSW	2	121,129,501 (GRCm39)	missense	probably damaging	0.99
R8365:Map1a	UTSW	2	121,138,528 (GRCm39)	missense	probably damaging	1.00
R8428:Map1a	UTSW	2	121,135,418 (GRCm39)	missense	probably benign	0.42
R8490:Map1a	UTSW	2	121,135,045 (GRCm39)	missense	possibly damaging	0.93
R8678:Map1a	UTSW	2	121,137,737 (GRCm39)	missense	probably damaging	1.00
R8798:Map1a	UTSW	2	121,132,768 (GRCm39)	missense	probably benign	0.20
R8857:Map1a	UTSW	2	121,138,098 (GRCm39)	missense	probably damaging	1.00
R8878:Map1a	UTSW	2	121,138,125 (GRCm39)	missense	probably damaging	1.00
R8909:Map1a	UTSW	2	121,129,391 (GRCm39)	missense	probably damaging	0.99
R8917:Map1a	UTSW	2	121,131,791 (GRCm39)	missense	possibly damaging	0.93
R8947:Map1a	UTSW	2	121,135,450 (GRCm39)	missense	probably benign	0.27
R9069:Map1a	UTSW	2	121,134,145 (GRCm39)	missense	probably benign	0.15
R9198:Map1a	UTSW	2	121,133,854 (GRCm39)	missense	probably benign	0.00
R9253:Map1a	UTSW	2	121,132,823 (GRCm39)	missense	probably benign	0.00
R9290:Map1a	UTSW	2	121,131,014 (GRCm39)	missense	probably damaging	1.00
R9300:Map1a	UTSW	2	121,133,446 (GRCm39)	missense	probably damaging	1.00
R9589:Map1a	UTSW	2	121,136,398 (GRCm39)	missense	probably damaging	1.00
R9680:Map1a	UTSW	2	121,132,865 (GRCm39)	missense	probably damaging	1.00
R9792:Map1a	UTSW	2	121,121,304 (GRCm39)	critical splice donor site	probably null
R9793:Map1a	UTSW	2	121,121,304 (GRCm39)	critical splice donor site	probably null
R9795:Map1a	UTSW	2	121,121,304 (GRCm39)	critical splice donor site	probably null
RF003:Map1a	UTSW	2	121,136,777 (GRCm39)	small insertion	probably benign
RF007:Map1a	UTSW	2	121,136,789 (GRCm39)	small insertion	probably benign
RF009:Map1a	UTSW	2	121,136,782 (GRCm39)	small insertion	probably benign
RF010:Map1a	UTSW	2	121,136,799 (GRCm39)	small insertion	probably benign
RF014:Map1a	UTSW	2	121,136,776 (GRCm39)	small insertion	probably benign
RF017:Map1a	UTSW	2	121,136,789 (GRCm39)	small insertion	probably benign
RF024:Map1a	UTSW	2	121,136,788 (GRCm39)	small insertion	probably benign
RF025:Map1a	UTSW	2	121,136,775 (GRCm39)	small insertion	probably benign
RF030:Map1a	UTSW	2	121,136,798 (GRCm39)	small insertion	probably benign
RF030:Map1a	UTSW	2	121,136,792 (GRCm39)	small insertion	probably benign
RF033:Map1a	UTSW	2	121,136,780 (GRCm39)	small insertion	probably benign
RF034:Map1a	UTSW	2	121,136,788 (GRCm39)	small insertion	probably benign
RF034:Map1a	UTSW	2	121,136,785 (GRCm39)	small insertion	probably benign
RF035:Map1a	UTSW	2	121,136,782 (GRCm39)	small insertion	probably benign
RF037:Map1a	UTSW	2	121,136,775 (GRCm39)	small insertion	probably benign
RF039:Map1a	UTSW	2	121,136,785 (GRCm39)	small insertion	probably benign
RF042:Map1a	UTSW	2	121,136,768 (GRCm39)	small insertion	probably benign
RF044:Map1a	UTSW	2	121,136,774 (GRCm39)	small insertion	probably benign
RF045:Map1a	UTSW	2	121,136,774 (GRCm39)	small insertion	probably benign
RF051:Map1a	UTSW	2	121,136,777 (GRCm39)	small insertion	probably benign
RF052:Map1a	UTSW	2	121,136,776 (GRCm39)	small insertion	probably benign
RF053:Map1a	UTSW	2	121,136,771 (GRCm39)	small insertion	probably benign
RF060:Map1a	UTSW	2	121,136,799 (GRCm39)	small insertion	probably benign
RF061:Map1a	UTSW	2	121,136,768 (GRCm39)	small insertion	probably benign
Z1176:Map1a	UTSW	2	121,133,719 (GRCm39)	missense	possibly damaging	0.95
Z1177:Map1a	UTSW	2	121,135,760 (GRCm39)	missense	probably damaging	0.99

Predicted Primers

PCR Primer
(F):5'- TTAGAACAAAGGGGTGCAGCCCTG -3'
(R):5'- ACCAGACCTTCCTCTCACAGCTTAG -3'

Sequencing Primer
(F):5'- GTGCAGCCCTGCAACAG -3'
(R):5'- TGACTTCCTGCTCAGGAGAC -3'

Posted On

2014-03-17