Incidental Mutation 'R1381:Dennd4c'
| ID |
162998 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dennd4c
|
| Ensembl Gene |
ENSMUSG00000038024 |
| Gene Name |
DENN domain containing 4C |
| Synonyms |
1700065A05Rik |
| MMRRC Submission |
039443-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R1381 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
4 |
| Chromosomal Location |
86666792-86768840 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to A
at 86692769 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Arginine to Lysine
at position 93
(R93K)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000123367
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000045512]
[ENSMUST00000082026]
[ENSMUST00000142837]
|
| AlphaFold |
A6H8H2 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000045512
AA Change: R93K
PolyPhen 2
Score 0.100 (Sensitivity: 0.93; Specificity: 0.86)
|
| SMART Domains |
Protein: ENSMUSP00000039860
Gene: ENSMUSG00000038024
AA Change: R93K
| Domain | Start | End | E-Value | Type |
|---|
|
internal_repeat_1
|
43 |
91 |
2.15e-5 |
PROSPERO |
|
uDENN
|
168 |
275 |
3.96e-24 |
SMART |
|
DENN
|
307 |
491 |
7.16e-72 |
SMART |
|
dDENN
|
557 |
631 |
1.85e-24 |
SMART |
|
low complexity region
|
983 |
1001 |
N/A |
INTRINSIC |
|
low complexity region
|
1013 |
1025 |
N/A |
INTRINSIC |
|
low complexity region
|
1045 |
1052 |
N/A |
INTRINSIC |
|
low complexity region
|
1102 |
1113 |
N/A |
INTRINSIC |
|
low complexity region
|
1175 |
1186 |
N/A |
INTRINSIC |
|
low complexity region
|
1377 |
1392 |
N/A |
INTRINSIC |
|
low complexity region
|
1472 |
1486 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000082026
AA Change: R93K
PolyPhen 2
Score 0.240 (Sensitivity: 0.91; Specificity: 0.88)
|
| SMART Domains |
Protein: ENSMUSP00000080685
Gene: ENSMUSG00000038024
AA Change: R93K
| Domain | Start | End | E-Value | Type |
|---|
|
internal_repeat_1
|
43 |
91 |
3.19e-5 |
PROSPERO |
|
uDENN
|
168 |
275 |
3.96e-24 |
SMART |
|
DENN
|
307 |
491 |
7.16e-72 |
SMART |
|
dDENN
|
557 |
631 |
1.85e-24 |
SMART |
|
low complexity region
|
983 |
1001 |
N/A |
INTRINSIC |
|
low complexity region
|
1013 |
1025 |
N/A |
INTRINSIC |
|
low complexity region
|
1045 |
1052 |
N/A |
INTRINSIC |
|
low complexity region
|
1102 |
1113 |
N/A |
INTRINSIC |
|
low complexity region
|
1175 |
1186 |
N/A |
INTRINSIC |
|
low complexity region
|
1377 |
1392 |
N/A |
INTRINSIC |
|
low complexity region
|
1472 |
1486 |
N/A |
INTRINSIC |
|
low complexity region
|
1724 |
1739 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000128710
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000142837
AA Change: R93K
PolyPhen 2
Score 0.240 (Sensitivity: 0.91; Specificity: 0.88)
|
| SMART Domains |
Protein: ENSMUSP00000123367
Gene: ENSMUSG00000038024
AA Change: R93K
| Domain | Start | End | E-Value | Type |
|---|
|
internal_repeat_1
|
43 |
91 |
2.68e-5 |
PROSPERO |
|
uDENN
|
168 |
275 |
3.96e-24 |
SMART |
|
DENN
|
307 |
491 |
7.16e-72 |
SMART |
|
dDENN
|
557 |
631 |
1.85e-24 |
SMART |
|
low complexity region
|
934 |
952 |
N/A |
INTRINSIC |
|
low complexity region
|
964 |
976 |
N/A |
INTRINSIC |
|
low complexity region
|
996 |
1003 |
N/A |
INTRINSIC |
|
low complexity region
|
1053 |
1064 |
N/A |
INTRINSIC |
|
low complexity region
|
1126 |
1137 |
N/A |
INTRINSIC |
|
low complexity region
|
1328 |
1343 |
N/A |
INTRINSIC |
|
low complexity region
|
1423 |
1437 |
N/A |
INTRINSIC |
|
low complexity region
|
1675 |
1690 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 98.8%
- 3x: 97.8%
- 10x: 94.4%
- 20x: 86.2%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 83 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4932414N04Rik |
C |
A |
2: 68,561,430 (GRCm39) |
F252L |
probably benign |
Het |
| Aadac |
A |
T |
3: 59,947,351 (GRCm39) |
M350L |
probably damaging |
Het |
| Agtrap |
G |
A |
4: 148,168,422 (GRCm39) |
T19I |
probably damaging |
Het |
| Apba3 |
C |
T |
10: 81,107,590 (GRCm39) |
T142M |
possibly damaging |
Het |
| Cd55b |
T |
A |
1: 130,347,412 (GRCm39) |
K133I |
probably damaging |
Het |
| Cep295 |
A |
C |
9: 15,233,861 (GRCm39) |
C2312G |
probably benign |
Het |
| Ces1a |
A |
G |
8: 93,760,659 (GRCm39) |
V231A |
probably damaging |
Het |
| Chdh |
C |
A |
14: 29,758,791 (GRCm39) |
L579I |
probably damaging |
Het |
| Cyb5r4 |
T |
A |
9: 86,904,286 (GRCm39) |
S19T |
probably benign |
Het |
| Cyp2d22 |
C |
A |
15: 82,256,709 (GRCm39) |
R355L |
probably benign |
Het |
| Dach2 |
T |
C |
X: 112,208,472 (GRCm39) |
Y117H |
probably damaging |
Het |
| Dph2 |
G |
T |
4: 117,746,865 (GRCm39) |
L452I |
probably damaging |
Het |
| Exoc6b |
T |
C |
6: 84,812,099 (GRCm39) |
D634G |
probably benign |
Het |
| Fam217b |
G |
A |
2: 178,062,218 (GRCm39) |
V61I |
probably benign |
Het |
| Fbln7 |
A |
C |
2: 128,719,299 (GRCm39) |
Q32P |
probably damaging |
Het |
| Fgfr1op2 |
A |
G |
6: 146,490,239 (GRCm39) |
Y46C |
probably damaging |
Het |
| Fhod3 |
T |
A |
18: 25,223,528 (GRCm39) |
I958N |
probably damaging |
Het |
| Foxp2 |
T |
A |
6: 15,409,765 (GRCm39) |
M455K |
possibly damaging |
Het |
| Gabrr2 |
G |
A |
4: 33,081,420 (GRCm39) |
G152D |
probably damaging |
Het |
| Galntl6 |
G |
T |
8: 58,925,989 (GRCm39) |
P92Q |
probably damaging |
Het |
| Gm5592 |
A |
T |
7: 40,935,596 (GRCm39) |
T33S |
probably benign |
Het |
| Grid2ip |
A |
T |
5: 143,348,406 (GRCm39) |
T166S |
probably benign |
Het |
| Grsf1 |
G |
A |
5: 88,813,723 (GRCm39) |
S225L |
probably benign |
Het |
| Hadha |
G |
T |
5: 30,333,834 (GRCm39) |
T395K |
probably benign |
Het |
| Hars2 |
C |
T |
18: 36,922,270 (GRCm39) |
A295V |
possibly damaging |
Het |
| Hsf5 |
T |
A |
11: 87,528,995 (GRCm39) |
S577T |
probably benign |
Het |
| Ice2 |
A |
G |
9: 69,307,809 (GRCm39) |
Y31C |
probably damaging |
Het |
| Ift80 |
A |
T |
3: 68,822,116 (GRCm39) |
I643N |
possibly damaging |
Het |
| Iglon5 |
A |
T |
7: 43,126,064 (GRCm39) |
D222E |
probably benign |
Het |
| Ilvbl |
C |
A |
10: 78,412,430 (GRCm39) |
S50R |
probably damaging |
Het |
| Invs |
C |
A |
4: 48,421,942 (GRCm39) |
S858* |
probably null |
Het |
| Ipo13 |
T |
G |
4: 117,761,592 (GRCm39) |
T508P |
probably damaging |
Het |
| Itgb4 |
T |
C |
11: 115,885,163 (GRCm39) |
I1015T |
probably benign |
Het |
| Kank4 |
A |
T |
4: 98,668,175 (GRCm39) |
W91R |
probably damaging |
Het |
| Kansl1l |
C |
T |
1: 66,760,063 (GRCm39) |
A906T |
probably benign |
Het |
| Klk4 |
G |
A |
7: 43,534,706 (GRCm39) |
V222M |
probably damaging |
Het |
| Lipo4 |
T |
A |
19: 33,476,741 (GRCm39) |
M336L |
probably benign |
Het |
| Lrig1 |
T |
C |
6: 94,583,111 (GRCm39) |
N1002D |
probably benign |
Het |
| Lzts3 |
A |
G |
2: 130,477,219 (GRCm39) |
S524P |
probably damaging |
Het |
| Maz |
A |
T |
7: 126,622,324 (GRCm39) |
C409* |
probably null |
Het |
| Mmp24 |
A |
T |
2: 155,656,047 (GRCm39) |
Q495L |
possibly damaging |
Het |
| Mrgpra9 |
C |
T |
7: 46,885,050 (GRCm39) |
V206I |
possibly damaging |
Het |
| Myof |
A |
G |
19: 37,983,933 (GRCm39) |
Y124H |
probably damaging |
Het |
| Nalcn |
A |
T |
14: 123,551,517 (GRCm39) |
V1030D |
probably damaging |
Het |
| Neb |
T |
A |
2: 52,150,544 (GRCm39) |
I2495F |
probably damaging |
Het |
| Nfix |
G |
A |
8: 85,453,155 (GRCm39) |
R300C |
probably damaging |
Het |
| Nrbf2 |
G |
A |
10: 67,103,605 (GRCm39) |
T166M |
probably damaging |
Het |
| Nup153 |
T |
C |
13: 46,842,657 (GRCm39) |
D837G |
probably damaging |
Het |
| Nup210 |
C |
A |
6: 91,052,942 (GRCm39) |
G331V |
probably damaging |
Het |
| Or5b97 |
T |
C |
19: 12,878,320 (GRCm39) |
T275A |
probably benign |
Het |
| Or5w18 |
T |
C |
2: 87,633,480 (GRCm39) |
L245P |
probably damaging |
Het |
| Or6z7 |
A |
G |
7: 6,484,008 (GRCm39) |
|
probably null |
Het |
| Or8b56 |
T |
A |
9: 38,739,634 (GRCm39) |
S210T |
probably benign |
Het |
| Pabpc4 |
T |
A |
4: 123,182,852 (GRCm39) |
L163H |
probably damaging |
Het |
| Pcdh7 |
T |
A |
5: 57,878,882 (GRCm39) |
Y126* |
probably null |
Het |
| Pdzd2 |
A |
G |
15: 12,385,525 (GRCm39) |
S1082P |
probably benign |
Het |
| Pkd2l1 |
T |
C |
19: 44,138,902 (GRCm39) |
I649M |
probably benign |
Het |
| Plcl2 |
G |
A |
17: 50,914,757 (GRCm39) |
E589K |
probably damaging |
Het |
| Plppr1 |
C |
A |
4: 49,337,674 (GRCm39) |
T325N |
possibly damaging |
Het |
| Prss8 |
GCTGCCCAAGTCCC |
GC |
7: 127,529,021 (GRCm39) |
|
probably benign |
Het |
| Ptcd2 |
A |
G |
13: 99,481,105 (GRCm39) |
S25P |
probably benign |
Het |
| Ptpro |
T |
A |
6: 137,420,592 (GRCm39) |
V1007D |
probably damaging |
Het |
| Rusc2 |
T |
A |
4: 43,416,137 (GRCm39) |
V481E |
probably damaging |
Het |
| Sephs2 |
G |
T |
7: 126,872,139 (GRCm39) |
T318K |
probably damaging |
Het |
| Sf3b1 |
T |
A |
1: 55,042,313 (GRCm39) |
I497L |
probably damaging |
Het |
| Slc30a7 |
C |
T |
3: 115,750,519 (GRCm39) |
|
probably null |
Het |
| Slc66a2 |
T |
G |
18: 80,326,529 (GRCm39) |
S126A |
probably benign |
Het |
| Smarca2 |
T |
C |
19: 26,608,228 (GRCm39) |
S96P |
probably damaging |
Het |
| Spata31d1c |
A |
C |
13: 65,184,368 (GRCm39) |
I637L |
probably benign |
Het |
| Ston2 |
A |
T |
12: 91,707,266 (GRCm39) |
S115T |
probably damaging |
Het |
| Tal2 |
A |
C |
4: 53,785,999 (GRCm39) |
E60A |
probably benign |
Het |
| Tdpoz3 |
A |
T |
3: 93,733,447 (GRCm39) |
T41S |
probably benign |
Het |
| Tent4b |
T |
A |
8: 88,969,937 (GRCm39) |
M203K |
possibly damaging |
Het |
| Tespa1 |
T |
C |
10: 130,196,560 (GRCm39) |
I166T |
probably benign |
Het |
| Thsd7a |
A |
T |
6: 12,555,438 (GRCm39) |
C149S |
probably damaging |
Het |
| Trav6-1 |
T |
A |
14: 52,875,967 (GRCm39) |
|
probably benign |
Het |
| Txnl4a |
T |
C |
18: 80,250,479 (GRCm39) |
V25A |
probably benign |
Het |
| Utp4 |
C |
A |
8: 107,632,908 (GRCm39) |
P297Q |
probably benign |
Het |
| Vmn1r34 |
T |
C |
6: 66,613,922 (GRCm39) |
Y272C |
probably damaging |
Het |
| Vmn2r112 |
A |
T |
17: 22,837,467 (GRCm39) |
I643F |
probably damaging |
Het |
| Vmn2r121 |
C |
A |
X: 123,037,837 (GRCm39) |
G728W |
probably damaging |
Het |
| Vmn2r24 |
T |
A |
6: 123,763,692 (GRCm39) |
S190T |
probably damaging |
Het |
| Zfp507 |
A |
G |
7: 35,475,435 (GRCm39) |
V926A |
possibly damaging |
Het |
|
| Other mutations in Dennd4c |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01309:Dennd4c
|
APN |
4 |
86,723,724 (GRCm39) |
splice site |
probably benign |
|
|
IGL01810:Dennd4c
|
APN |
4 |
86,717,788 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL02203:Dennd4c
|
APN |
4 |
86,721,173 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02217:Dennd4c
|
APN |
4 |
86,732,036 (GRCm39) |
missense |
probably benign |
|
|
IGL02236:Dennd4c
|
APN |
4 |
86,725,672 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
IGL02256:Dennd4c
|
APN |
4 |
86,717,778 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02396:Dennd4c
|
APN |
4 |
86,743,237 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02523:Dennd4c
|
APN |
4 |
86,692,490 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02615:Dennd4c
|
APN |
4 |
86,739,704 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03069:Dennd4c
|
APN |
4 |
86,692,674 (GRCm39) |
nonsense |
probably null |
|
|
IGL03116:Dennd4c
|
APN |
4 |
86,707,057 (GRCm39) |
splice site |
probably benign |
|
|
IGL03117:Dennd4c
|
APN |
4 |
86,696,140 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL03273:Dennd4c
|
APN |
4 |
86,696,033 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03329:Dennd4c
|
APN |
4 |
86,696,113 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03365:Dennd4c
|
APN |
4 |
86,725,663 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
PIT4486001:Dennd4c
|
UTSW |
4 |
86,717,701 (GRCm39) |
nonsense |
probably null |
|
|
R0010:Dennd4c
|
UTSW |
4 |
86,699,814 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0032:Dennd4c
|
UTSW |
4 |
86,746,387 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0032:Dennd4c
|
UTSW |
4 |
86,746,387 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0092:Dennd4c
|
UTSW |
4 |
86,699,844 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0103:Dennd4c
|
UTSW |
4 |
86,730,683 (GRCm39) |
missense |
probably benign |
0.07 |
|
R0103:Dennd4c
|
UTSW |
4 |
86,730,683 (GRCm39) |
missense |
probably benign |
0.07 |
|
R0511:Dennd4c
|
UTSW |
4 |
86,744,259 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0515:Dennd4c
|
UTSW |
4 |
86,731,703 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R0578:Dennd4c
|
UTSW |
4 |
86,730,659 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0759:Dennd4c
|
UTSW |
4 |
86,707,066 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0784:Dennd4c
|
UTSW |
4 |
86,763,145 (GRCm39) |
missense |
probably benign |
0.37 |
|
R1156:Dennd4c
|
UTSW |
4 |
86,725,703 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1370:Dennd4c
|
UTSW |
4 |
86,729,747 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1569:Dennd4c
|
UTSW |
4 |
86,704,331 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
R1747:Dennd4c
|
UTSW |
4 |
86,725,675 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1764:Dennd4c
|
UTSW |
4 |
86,721,247 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1838:Dennd4c
|
UTSW |
4 |
86,743,415 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1997:Dennd4c
|
UTSW |
4 |
86,755,634 (GRCm39) |
missense |
probably benign |
|
|
R2244:Dennd4c
|
UTSW |
4 |
86,692,780 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2348:Dennd4c
|
UTSW |
4 |
86,729,764 (GRCm39) |
missense |
probably benign |
0.04 |
|
R2968:Dennd4c
|
UTSW |
4 |
86,699,881 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R3033:Dennd4c
|
UTSW |
4 |
86,743,557 (GRCm39) |
small deletion |
probably benign |
|
|
R3401:Dennd4c
|
UTSW |
4 |
86,692,780 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3402:Dennd4c
|
UTSW |
4 |
86,692,780 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3403:Dennd4c
|
UTSW |
4 |
86,692,780 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3855:Dennd4c
|
UTSW |
4 |
86,698,084 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3939:Dennd4c
|
UTSW |
4 |
86,692,517 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4164:Dennd4c
|
UTSW |
4 |
86,725,764 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4384:Dennd4c
|
UTSW |
4 |
86,729,687 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4435:Dennd4c
|
UTSW |
4 |
86,716,312 (GRCm39) |
missense |
probably benign |
0.44 |
|
R4788:Dennd4c
|
UTSW |
4 |
86,738,200 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4801:Dennd4c
|
UTSW |
4 |
86,738,121 (GRCm39) |
nonsense |
probably null |
|
|
R4802:Dennd4c
|
UTSW |
4 |
86,738,121 (GRCm39) |
nonsense |
probably null |
|
|
R4818:Dennd4c
|
UTSW |
4 |
86,743,511 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4923:Dennd4c
|
UTSW |
4 |
86,725,775 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4958:Dennd4c
|
UTSW |
4 |
86,699,916 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5025:Dennd4c
|
UTSW |
4 |
86,713,536 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5434:Dennd4c
|
UTSW |
4 |
86,729,693 (GRCm39) |
missense |
probably benign |
0.10 |
|
R5662:Dennd4c
|
UTSW |
4 |
86,713,525 (GRCm39) |
missense |
probably benign |
0.13 |
|
R5802:Dennd4c
|
UTSW |
4 |
86,729,690 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5849:Dennd4c
|
UTSW |
4 |
86,744,223 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R5861:Dennd4c
|
UTSW |
4 |
86,709,589 (GRCm39) |
missense |
probably benign |
0.30 |
|
R5970:Dennd4c
|
UTSW |
4 |
86,743,749 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6163:Dennd4c
|
UTSW |
4 |
86,723,828 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R6356:Dennd4c
|
UTSW |
4 |
86,743,686 (GRCm39) |
missense |
probably benign |
|
|
R6661:Dennd4c
|
UTSW |
4 |
86,717,626 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R6855:Dennd4c
|
UTSW |
4 |
86,754,694 (GRCm39) |
missense |
probably benign |
|
|
R6983:Dennd4c
|
UTSW |
4 |
86,717,730 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7035:Dennd4c
|
UTSW |
4 |
86,730,574 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7126:Dennd4c
|
UTSW |
4 |
86,725,667 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7185:Dennd4c
|
UTSW |
4 |
86,729,687 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7212:Dennd4c
|
UTSW |
4 |
86,721,228 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7324:Dennd4c
|
UTSW |
4 |
86,747,975 (GRCm39) |
missense |
unknown |
|
|
R7329:Dennd4c
|
UTSW |
4 |
86,698,111 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R7329:Dennd4c
|
UTSW |
4 |
86,759,318 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7466:Dennd4c
|
UTSW |
4 |
86,692,568 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7479:Dennd4c
|
UTSW |
4 |
86,717,590 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7538:Dennd4c
|
UTSW |
4 |
86,692,753 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7599:Dennd4c
|
UTSW |
4 |
86,729,849 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7688:Dennd4c
|
UTSW |
4 |
86,713,377 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7725:Dennd4c
|
UTSW |
4 |
86,704,330 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7751:Dennd4c
|
UTSW |
4 |
86,747,179 (GRCm39) |
missense |
probably benign |
0.05 |
|
R7790:Dennd4c
|
UTSW |
4 |
86,717,754 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8056:Dennd4c
|
UTSW |
4 |
86,763,213 (GRCm39) |
missense |
probably null |
0.71 |
|
R8307:Dennd4c
|
UTSW |
4 |
86,744,109 (GRCm39) |
missense |
probably benign |
0.12 |
|
R8494:Dennd4c
|
UTSW |
4 |
86,759,312 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8531:Dennd4c
|
UTSW |
4 |
86,744,319 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9014:Dennd4c
|
UTSW |
4 |
86,754,666 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9014:Dennd4c
|
UTSW |
4 |
86,739,702 (GRCm39) |
missense |
probably benign |
0.07 |
|
R9017:Dennd4c
|
UTSW |
4 |
86,743,349 (GRCm39) |
missense |
probably benign |
0.33 |
|
R9142:Dennd4c
|
UTSW |
4 |
86,755,637 (GRCm39) |
missense |
probably benign |
0.32 |
|
R9224:Dennd4c
|
UTSW |
4 |
86,738,170 (GRCm39) |
nonsense |
probably null |
|
|
R9570:Dennd4c
|
UTSW |
4 |
86,747,208 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R9644:Dennd4c
|
UTSW |
4 |
86,713,363 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9649:Dennd4c
|
UTSW |
4 |
86,743,160 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9658:Dennd4c
|
UTSW |
4 |
86,754,625 (GRCm39) |
nonsense |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- AGCTCCAATCACAGACATTGCTGTTAT -3'
(R):5'- GGAATGCCCTTCCCTAAAGATGTTCAT -3'
Sequencing Primer
(F):5'- CAGCACTCCAAGCAAACTTG -3'
(R):5'- agcactgactcctctccc -3'
|
| Posted On |
2014-03-17 |
Incidental Mutation