Incidental Mutation 'R1381:Pcdh7'
| ID |
163006 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Pcdh7
|
| Ensembl Gene |
ENSMUSG00000029108 |
| Gene Name |
protocadherin 7 |
| Synonyms |
BH-protocadherin |
| MMRRC Submission |
039443-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.141)
|
| Stock # |
R1381 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
5 |
| Chromosomal Location |
57875309-58290572 bp(+) (GRCm39) |
| Type of Mutation |
nonsense |
| DNA Base Change (assembly) |
T to A
at 57878882 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Tyrosine to Stop codon
at position 126
(Y126*)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000068110]
[ENSMUST00000094783]
[ENSMUST00000191837]
[ENSMUST00000199310]
|
| AlphaFold |
A0A0A6YY83 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000068110
AA Change: Y812*
|
| SMART Domains |
Protein: ENSMUSP00000066306
Gene: ENSMUSG00000029108
AA Change: Y812*
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
30 |
N/A |
INTRINSIC |
|
CA
|
48 |
141 |
7.29e-4 |
SMART |
|
CA
|
165 |
306 |
1.13e-18 |
SMART |
|
CA
|
330 |
413 |
2.12e-23 |
SMART |
|
CA
|
445 |
533 |
1.53e-20 |
SMART |
|
CA
|
557 |
637 |
1.36e-26 |
SMART |
|
CA
|
661 |
740 |
2.38e-26 |
SMART |
|
CA
|
766 |
847 |
2.01e-15 |
SMART |
|
transmembrane domain
|
878 |
900 |
N/A |
INTRINSIC |
|
low complexity region
|
929 |
944 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000094783
AA Change: Y812*
|
| SMART Domains |
Protein: ENSMUSP00000092376
Gene: ENSMUSG00000029108
AA Change: Y812*
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
30 |
N/A |
INTRINSIC |
|
CA
|
48 |
141 |
7.29e-4 |
SMART |
|
CA
|
165 |
306 |
1.13e-18 |
SMART |
|
CA
|
330 |
413 |
2.12e-23 |
SMART |
|
CA
|
445 |
533 |
1.53e-20 |
SMART |
|
CA
|
557 |
637 |
1.36e-26 |
SMART |
|
CA
|
661 |
740 |
2.38e-26 |
SMART |
|
CA
|
766 |
847 |
2.01e-15 |
SMART |
|
transmembrane domain
|
878 |
900 |
N/A |
INTRINSIC |
|
low complexity region
|
929 |
944 |
N/A |
INTRINSIC |
|
low complexity region
|
1088 |
1099 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000180708
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000191837
AA Change: Y812*
|
| SMART Domains |
Protein: ENSMUSP00000142319
Gene: ENSMUSG00000029108
AA Change: Y812*
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
30 |
N/A |
INTRINSIC |
|
CA
|
48 |
141 |
7.29e-4 |
SMART |
|
CA
|
165 |
306 |
1.13e-18 |
SMART |
|
CA
|
330 |
413 |
2.12e-23 |
SMART |
|
CA
|
445 |
533 |
1.53e-20 |
SMART |
|
CA
|
557 |
637 |
1.36e-26 |
SMART |
|
CA
|
661 |
740 |
2.38e-26 |
SMART |
|
CA
|
766 |
847 |
2.01e-15 |
SMART |
|
transmembrane domain
|
878 |
900 |
N/A |
INTRINSIC |
|
low complexity region
|
929 |
944 |
N/A |
INTRINSIC |
|
low complexity region
|
1088 |
1099 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000192048
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000192287
AA Change: Y472*
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000193156
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000195156
AA Change: Y126*
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000200266
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000199310
|
| SMART Domains |
Protein: ENSMUSP00000143387
Gene: ENSMUSG00000029108
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Protocadherin
|
1 |
79 |
5.1e-40 |
PFAM |
|
low complexity region
|
112 |
123 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 98.8%
- 3x: 97.8%
- 10x: 94.4%
- 20x: 86.2%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The gene encodes a protein with an extracellular domain containing 7 cadherin repeats. The gene product is an integral membrane protein that is thought to function in cell-cell recognition and adhesion. Alternative splicing yields isoforms with unique cytoplasmic tails. [provided by RefSeq, Jul 2008]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 83 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4932414N04Rik |
C |
A |
2: 68,561,430 (GRCm39) |
F252L |
probably benign |
Het |
| Aadac |
A |
T |
3: 59,947,351 (GRCm39) |
M350L |
probably damaging |
Het |
| Agtrap |
G |
A |
4: 148,168,422 (GRCm39) |
T19I |
probably damaging |
Het |
| Apba3 |
C |
T |
10: 81,107,590 (GRCm39) |
T142M |
possibly damaging |
Het |
| Cd55b |
T |
A |
1: 130,347,412 (GRCm39) |
K133I |
probably damaging |
Het |
| Cep295 |
A |
C |
9: 15,233,861 (GRCm39) |
C2312G |
probably benign |
Het |
| Ces1a |
A |
G |
8: 93,760,659 (GRCm39) |
V231A |
probably damaging |
Het |
| Chdh |
C |
A |
14: 29,758,791 (GRCm39) |
L579I |
probably damaging |
Het |
| Cyb5r4 |
T |
A |
9: 86,904,286 (GRCm39) |
S19T |
probably benign |
Het |
| Cyp2d22 |
C |
A |
15: 82,256,709 (GRCm39) |
R355L |
probably benign |
Het |
| Dach2 |
T |
C |
X: 112,208,472 (GRCm39) |
Y117H |
probably damaging |
Het |
| Dennd4c |
G |
A |
4: 86,692,769 (GRCm39) |
R93K |
probably benign |
Het |
| Dph2 |
G |
T |
4: 117,746,865 (GRCm39) |
L452I |
probably damaging |
Het |
| Exoc6b |
T |
C |
6: 84,812,099 (GRCm39) |
D634G |
probably benign |
Het |
| Fam217b |
G |
A |
2: 178,062,218 (GRCm39) |
V61I |
probably benign |
Het |
| Fbln7 |
A |
C |
2: 128,719,299 (GRCm39) |
Q32P |
probably damaging |
Het |
| Fgfr1op2 |
A |
G |
6: 146,490,239 (GRCm39) |
Y46C |
probably damaging |
Het |
| Fhod3 |
T |
A |
18: 25,223,528 (GRCm39) |
I958N |
probably damaging |
Het |
| Foxp2 |
T |
A |
6: 15,409,765 (GRCm39) |
M455K |
possibly damaging |
Het |
| Gabrr2 |
G |
A |
4: 33,081,420 (GRCm39) |
G152D |
probably damaging |
Het |
| Galntl6 |
G |
T |
8: 58,925,989 (GRCm39) |
P92Q |
probably damaging |
Het |
| Gm5592 |
A |
T |
7: 40,935,596 (GRCm39) |
T33S |
probably benign |
Het |
| Grid2ip |
A |
T |
5: 143,348,406 (GRCm39) |
T166S |
probably benign |
Het |
| Grsf1 |
G |
A |
5: 88,813,723 (GRCm39) |
S225L |
probably benign |
Het |
| Hadha |
G |
T |
5: 30,333,834 (GRCm39) |
T395K |
probably benign |
Het |
| Hars2 |
C |
T |
18: 36,922,270 (GRCm39) |
A295V |
possibly damaging |
Het |
| Hsf5 |
T |
A |
11: 87,528,995 (GRCm39) |
S577T |
probably benign |
Het |
| Ice2 |
A |
G |
9: 69,307,809 (GRCm39) |
Y31C |
probably damaging |
Het |
| Ift80 |
A |
T |
3: 68,822,116 (GRCm39) |
I643N |
possibly damaging |
Het |
| Iglon5 |
A |
T |
7: 43,126,064 (GRCm39) |
D222E |
probably benign |
Het |
| Ilvbl |
C |
A |
10: 78,412,430 (GRCm39) |
S50R |
probably damaging |
Het |
| Invs |
C |
A |
4: 48,421,942 (GRCm39) |
S858* |
probably null |
Het |
| Ipo13 |
T |
G |
4: 117,761,592 (GRCm39) |
T508P |
probably damaging |
Het |
| Itgb4 |
T |
C |
11: 115,885,163 (GRCm39) |
I1015T |
probably benign |
Het |
| Kank4 |
A |
T |
4: 98,668,175 (GRCm39) |
W91R |
probably damaging |
Het |
| Kansl1l |
C |
T |
1: 66,760,063 (GRCm39) |
A906T |
probably benign |
Het |
| Klk4 |
G |
A |
7: 43,534,706 (GRCm39) |
V222M |
probably damaging |
Het |
| Lipo4 |
T |
A |
19: 33,476,741 (GRCm39) |
M336L |
probably benign |
Het |
| Lrig1 |
T |
C |
6: 94,583,111 (GRCm39) |
N1002D |
probably benign |
Het |
| Lzts3 |
A |
G |
2: 130,477,219 (GRCm39) |
S524P |
probably damaging |
Het |
| Maz |
A |
T |
7: 126,622,324 (GRCm39) |
C409* |
probably null |
Het |
| Mmp24 |
A |
T |
2: 155,656,047 (GRCm39) |
Q495L |
possibly damaging |
Het |
| Mrgpra9 |
C |
T |
7: 46,885,050 (GRCm39) |
V206I |
possibly damaging |
Het |
| Myof |
A |
G |
19: 37,983,933 (GRCm39) |
Y124H |
probably damaging |
Het |
| Nalcn |
A |
T |
14: 123,551,517 (GRCm39) |
V1030D |
probably damaging |
Het |
| Neb |
T |
A |
2: 52,150,544 (GRCm39) |
I2495F |
probably damaging |
Het |
| Nfix |
G |
A |
8: 85,453,155 (GRCm39) |
R300C |
probably damaging |
Het |
| Nrbf2 |
G |
A |
10: 67,103,605 (GRCm39) |
T166M |
probably damaging |
Het |
| Nup153 |
T |
C |
13: 46,842,657 (GRCm39) |
D837G |
probably damaging |
Het |
| Nup210 |
C |
A |
6: 91,052,942 (GRCm39) |
G331V |
probably damaging |
Het |
| Or5b97 |
T |
C |
19: 12,878,320 (GRCm39) |
T275A |
probably benign |
Het |
| Or5w18 |
T |
C |
2: 87,633,480 (GRCm39) |
L245P |
probably damaging |
Het |
| Or6z7 |
A |
G |
7: 6,484,008 (GRCm39) |
|
probably null |
Het |
| Or8b56 |
T |
A |
9: 38,739,634 (GRCm39) |
S210T |
probably benign |
Het |
| Pabpc4 |
T |
A |
4: 123,182,852 (GRCm39) |
L163H |
probably damaging |
Het |
| Pdzd2 |
A |
G |
15: 12,385,525 (GRCm39) |
S1082P |
probably benign |
Het |
| Pkd2l1 |
T |
C |
19: 44,138,902 (GRCm39) |
I649M |
probably benign |
Het |
| Plcl2 |
G |
A |
17: 50,914,757 (GRCm39) |
E589K |
probably damaging |
Het |
| Plppr1 |
C |
A |
4: 49,337,674 (GRCm39) |
T325N |
possibly damaging |
Het |
| Prss8 |
GCTGCCCAAGTCCC |
GC |
7: 127,529,021 (GRCm39) |
|
probably benign |
Het |
| Ptcd2 |
A |
G |
13: 99,481,105 (GRCm39) |
S25P |
probably benign |
Het |
| Ptpro |
T |
A |
6: 137,420,592 (GRCm39) |
V1007D |
probably damaging |
Het |
| Rusc2 |
T |
A |
4: 43,416,137 (GRCm39) |
V481E |
probably damaging |
Het |
| Sephs2 |
G |
T |
7: 126,872,139 (GRCm39) |
T318K |
probably damaging |
Het |
| Sf3b1 |
T |
A |
1: 55,042,313 (GRCm39) |
I497L |
probably damaging |
Het |
| Slc30a7 |
C |
T |
3: 115,750,519 (GRCm39) |
|
probably null |
Het |
| Slc66a2 |
T |
G |
18: 80,326,529 (GRCm39) |
S126A |
probably benign |
Het |
| Smarca2 |
T |
C |
19: 26,608,228 (GRCm39) |
S96P |
probably damaging |
Het |
| Spata31d1c |
A |
C |
13: 65,184,368 (GRCm39) |
I637L |
probably benign |
Het |
| Ston2 |
A |
T |
12: 91,707,266 (GRCm39) |
S115T |
probably damaging |
Het |
| Tal2 |
A |
C |
4: 53,785,999 (GRCm39) |
E60A |
probably benign |
Het |
| Tdpoz3 |
A |
T |
3: 93,733,447 (GRCm39) |
T41S |
probably benign |
Het |
| Tent4b |
T |
A |
8: 88,969,937 (GRCm39) |
M203K |
possibly damaging |
Het |
| Tespa1 |
T |
C |
10: 130,196,560 (GRCm39) |
I166T |
probably benign |
Het |
| Thsd7a |
A |
T |
6: 12,555,438 (GRCm39) |
C149S |
probably damaging |
Het |
| Trav6-1 |
T |
A |
14: 52,875,967 (GRCm39) |
|
probably benign |
Het |
| Txnl4a |
T |
C |
18: 80,250,479 (GRCm39) |
V25A |
probably benign |
Het |
| Utp4 |
C |
A |
8: 107,632,908 (GRCm39) |
P297Q |
probably benign |
Het |
| Vmn1r34 |
T |
C |
6: 66,613,922 (GRCm39) |
Y272C |
probably damaging |
Het |
| Vmn2r112 |
A |
T |
17: 22,837,467 (GRCm39) |
I643F |
probably damaging |
Het |
| Vmn2r121 |
C |
A |
X: 123,037,837 (GRCm39) |
G728W |
probably damaging |
Het |
| Vmn2r24 |
T |
A |
6: 123,763,692 (GRCm39) |
S190T |
probably damaging |
Het |
| Zfp507 |
A |
G |
7: 35,475,435 (GRCm39) |
V926A |
possibly damaging |
Het |
|
| Other mutations in Pcdh7 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00790:Pcdh7
|
APN |
5 |
57,878,806 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00920:Pcdh7
|
APN |
5 |
57,877,473 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL00990:Pcdh7
|
APN |
5 |
57,877,806 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL01367:Pcdh7
|
APN |
5 |
58,286,566 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
IGL01388:Pcdh7
|
APN |
5 |
57,877,546 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01543:Pcdh7
|
APN |
5 |
57,878,107 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01750:Pcdh7
|
APN |
5 |
57,877,764 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02010:Pcdh7
|
APN |
5 |
58,286,597 (GRCm39) |
missense |
probably benign |
|
|
IGL02014:Pcdh7
|
APN |
5 |
57,877,045 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL02269:Pcdh7
|
APN |
5 |
58,070,664 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03051:Pcdh7
|
APN |
5 |
58,286,415 (GRCm39) |
missense |
probably damaging |
0.99 |
|
floated
|
UTSW |
5 |
57,878,704 (GRCm39) |
missense |
probably damaging |
1.00 |
|
proposed
|
UTSW |
5 |
57,879,582 (GRCm39) |
missense |
probably damaging |
0.99 |
|
P0037:Pcdh7
|
UTSW |
5 |
58,070,590 (GRCm39) |
missense |
probably benign |
0.17 |
|
R0003:Pcdh7
|
UTSW |
5 |
58,070,590 (GRCm39) |
missense |
probably benign |
0.17 |
|
R0421:Pcdh7
|
UTSW |
5 |
57,877,402 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0551:Pcdh7
|
UTSW |
5 |
57,879,336 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0562:Pcdh7
|
UTSW |
5 |
57,877,405 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0732:Pcdh7
|
UTSW |
5 |
57,878,657 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0755:Pcdh7
|
UTSW |
5 |
57,877,664 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R1080:Pcdh7
|
UTSW |
5 |
57,876,768 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1591:Pcdh7
|
UTSW |
5 |
57,877,764 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1891:Pcdh7
|
UTSW |
5 |
57,878,217 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2011:Pcdh7
|
UTSW |
5 |
57,876,971 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2140:Pcdh7
|
UTSW |
5 |
58,286,338 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2147:Pcdh7
|
UTSW |
5 |
58,286,458 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R2848:Pcdh7
|
UTSW |
5 |
57,877,618 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2867:Pcdh7
|
UTSW |
5 |
57,879,236 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2867:Pcdh7
|
UTSW |
5 |
57,879,236 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3719:Pcdh7
|
UTSW |
5 |
58,286,374 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4075:Pcdh7
|
UTSW |
5 |
57,879,150 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4231:Pcdh7
|
UTSW |
5 |
57,876,631 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R4236:Pcdh7
|
UTSW |
5 |
57,876,631 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R4352:Pcdh7
|
UTSW |
5 |
57,879,361 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R4420:Pcdh7
|
UTSW |
5 |
58,286,512 (GRCm39) |
missense |
probably benign |
0.03 |
|
R4449:Pcdh7
|
UTSW |
5 |
57,877,827 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4584:Pcdh7
|
UTSW |
5 |
57,878,625 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4686:Pcdh7
|
UTSW |
5 |
58,286,511 (GRCm39) |
missense |
probably benign |
|
|
R4837:Pcdh7
|
UTSW |
5 |
57,877,753 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R4838:Pcdh7
|
UTSW |
5 |
57,878,146 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4947:Pcdh7
|
UTSW |
5 |
57,879,258 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5053:Pcdh7
|
UTSW |
5 |
57,878,943 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5068:Pcdh7
|
UTSW |
5 |
57,879,508 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5117:Pcdh7
|
UTSW |
5 |
57,879,090 (GRCm39) |
missense |
probably benign |
0.09 |
|
R5132:Pcdh7
|
UTSW |
5 |
57,885,463 (GRCm39) |
missense |
probably benign |
|
|
R5248:Pcdh7
|
UTSW |
5 |
58,286,515 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5294:Pcdh7
|
UTSW |
5 |
57,885,453 (GRCm39) |
splice site |
probably null |
|
|
R5420:Pcdh7
|
UTSW |
5 |
57,877,529 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5777:Pcdh7
|
UTSW |
5 |
57,876,856 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5800:Pcdh7
|
UTSW |
5 |
57,879,567 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5834:Pcdh7
|
UTSW |
5 |
57,878,970 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R5870:Pcdh7
|
UTSW |
5 |
57,877,753 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R5917:Pcdh7
|
UTSW |
5 |
57,879,097 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6014:Pcdh7
|
UTSW |
5 |
57,878,497 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6193:Pcdh7
|
UTSW |
5 |
57,877,666 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6240:Pcdh7
|
UTSW |
5 |
57,878,704 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6335:Pcdh7
|
UTSW |
5 |
58,099,607 (GRCm39) |
splice site |
probably null |
|
|
R6418:Pcdh7
|
UTSW |
5 |
57,879,046 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6907:Pcdh7
|
UTSW |
5 |
57,876,471 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R7058:Pcdh7
|
UTSW |
5 |
57,879,582 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7069:Pcdh7
|
UTSW |
5 |
57,877,126 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7073:Pcdh7
|
UTSW |
5 |
57,878,299 (GRCm39) |
missense |
probably benign |
0.19 |
|
R7463:Pcdh7
|
UTSW |
5 |
57,878,340 (GRCm39) |
missense |
probably benign |
0.06 |
|
R7509:Pcdh7
|
UTSW |
5 |
57,877,529 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7588:Pcdh7
|
UTSW |
5 |
57,877,246 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7707:Pcdh7
|
UTSW |
5 |
57,877,672 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7734:Pcdh7
|
UTSW |
5 |
57,876,976 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7899:Pcdh7
|
UTSW |
5 |
57,877,152 (GRCm39) |
missense |
probably benign |
|
|
R8194:Pcdh7
|
UTSW |
5 |
57,877,678 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8480:Pcdh7
|
UTSW |
5 |
58,286,407 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8890:Pcdh7
|
UTSW |
5 |
57,876,717 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8906:Pcdh7
|
UTSW |
5 |
57,879,154 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8990:Pcdh7
|
UTSW |
5 |
57,879,364 (GRCm39) |
missense |
probably benign |
0.06 |
|
R9264:Pcdh7
|
UTSW |
5 |
58,286,663 (GRCm39) |
missense |
probably benign |
0.09 |
|
R9272:Pcdh7
|
UTSW |
5 |
57,878,779 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R9294:Pcdh7
|
UTSW |
5 |
57,878,677 (GRCm39) |
missense |
probably benign |
0.39 |
|
R9518:Pcdh7
|
UTSW |
5 |
58,070,513 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R9597:Pcdh7
|
UTSW |
5 |
57,877,197 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R9642:Pcdh7
|
UTSW |
5 |
57,876,717 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9745:Pcdh7
|
UTSW |
5 |
57,879,622 (GRCm39) |
critical splice donor site |
probably null |
|
|
X0021:Pcdh7
|
UTSW |
5 |
57,878,826 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
X0026:Pcdh7
|
UTSW |
5 |
57,876,721 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Pcdh7
|
UTSW |
5 |
57,877,006 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGGATGAAAATGACAACGCTCCCAC -3'
(R):5'- AGCTTGGGTCACCAGCTATATCCTG -3'
Sequencing Primer
(F):5'- GAAACATTTCCTACACGTTGCTG -3'
(R):5'- TCACCAGCTATATCCTGGGTGAG -3'
|
| Posted On |
2014-03-17 |
Incidental Mutation