Incidental Mutation 'R1491:Hdac5'
| ID |
163764 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Hdac5
|
| Ensembl Gene |
ENSMUSG00000008855 |
| Gene Name |
histone deacetylase 5 |
| Synonyms |
mHDA1 |
| MMRRC Submission |
039543-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R1491 (G1)
|
| Quality Score |
114 |
|
Status
|
Not validated
|
| Chromosome |
11 |
| Chromosomal Location |
102085244-102120968 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 102092079 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Alanine
at position 670
(V670A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000102770
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000008999]
[ENSMUST00000107150]
[ENSMUST00000107151]
[ENSMUST00000107152]
[ENSMUST00000124077]
[ENSMUST00000140962]
[ENSMUST00000156337]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000008999
AA Change: V688A
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000008999
Gene: ENSMUSG00000008855
AA Change: V688A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
58 |
75 |
N/A |
INTRINSIC |
|
Pfam:HDAC4_Gln
|
86 |
174 |
1e-30 |
PFAM |
|
low complexity region
|
233 |
247 |
N/A |
INTRINSIC |
|
low complexity region
|
322 |
337 |
N/A |
INTRINSIC |
|
low complexity region
|
502 |
541 |
N/A |
INTRINSIC |
|
low complexity region
|
560 |
577 |
N/A |
INTRINSIC |
|
coiled coil region
|
583 |
617 |
N/A |
INTRINSIC |
|
Pfam:Hist_deacetyl
|
704 |
1034 |
1.4e-81 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000107150
AA Change: V669A
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000102768
Gene: ENSMUSG00000008855
AA Change: V669A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
39 |
56 |
N/A |
INTRINSIC |
|
Pfam:HDAC4_Gln
|
66 |
155 |
5.1e-37 |
PFAM |
|
low complexity region
|
214 |
228 |
N/A |
INTRINSIC |
|
low complexity region
|
303 |
318 |
N/A |
INTRINSIC |
|
low complexity region
|
483 |
522 |
N/A |
INTRINSIC |
|
low complexity region
|
541 |
558 |
N/A |
INTRINSIC |
|
coiled coil region
|
564 |
598 |
N/A |
INTRINSIC |
|
Pfam:Hist_deacetyl
|
685 |
1015 |
9.4e-91 |
PFAM |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000107151
AA Change: V670A
|
| SMART Domains |
Protein: ENSMUSP00000102769
Gene: ENSMUSG00000008855
AA Change: V670A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
40 |
57 |
N/A |
INTRINSIC |
|
Pfam:HDAC4_Gln
|
67 |
156 |
1.1e-37 |
PFAM |
|
low complexity region
|
215 |
229 |
N/A |
INTRINSIC |
|
low complexity region
|
304 |
319 |
N/A |
INTRINSIC |
|
low complexity region
|
484 |
523 |
N/A |
INTRINSIC |
|
low complexity region
|
542 |
559 |
N/A |
INTRINSIC |
|
coiled coil region
|
565 |
599 |
N/A |
INTRINSIC |
|
Pfam:Hist_deacetyl
|
618 |
931 |
1.2e-82 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000107152
AA Change: V670A
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000102770
Gene: ENSMUSG00000008855
AA Change: V670A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
40 |
57 |
N/A |
INTRINSIC |
|
Pfam:HDAC4_Gln
|
67 |
156 |
3.7e-37 |
PFAM |
|
low complexity region
|
215 |
229 |
N/A |
INTRINSIC |
|
low complexity region
|
304 |
319 |
N/A |
INTRINSIC |
|
low complexity region
|
484 |
523 |
N/A |
INTRINSIC |
|
low complexity region
|
542 |
559 |
N/A |
INTRINSIC |
|
coiled coil region
|
565 |
599 |
N/A |
INTRINSIC |
|
Pfam:Hist_deacetyl
|
686 |
1016 |
6.4e-91 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000124077
|
| SMART Domains |
Protein: ENSMUSP00000116672
Gene: ENSMUSG00000008855
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
37 |
50 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000126453
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000133651
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000149087
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000136304
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000137787
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000145540
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000155065
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000150965
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000140481
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000140962
|
| SMART Domains |
Protein: ENSMUSP00000115435
Gene: ENSMUSG00000008855
| Domain | Start | End | E-Value | Type |
|---|
|
PDB:2VQQ|B
|
1 |
71 |
3e-21 |
PDB |
|
transmembrane domain
|
118 |
135 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000156337
|
| SMART Domains |
Protein: ENSMUSP00000116646
Gene: ENSMUSG00000008855
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
1 |
15 |
N/A |
INTRINSIC |
|
Pfam:HDAC4_Gln
|
25 |
114 |
2e-38 |
PFAM |
|
| Coding Region Coverage |
- 1x: 99.0%
- 3x: 98.1%
- 10x: 95.5%
- 20x: 90.2%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
PHENOTYPE: Homozygous null mice are viable and display cardiac hypertrophy. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 81 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| A730018C14Rik |
T |
A |
12: 112,381,489 (GRCm39) |
|
noncoding transcript |
Het |
| Acss3 |
A |
G |
10: 106,773,169 (GRCm39) |
S606P |
probably benign |
Het |
| Adamts13 |
C |
T |
2: 26,868,327 (GRCm39) |
T146M |
probably damaging |
Het |
| Adora2b |
G |
A |
11: 62,156,363 (GRCm39) |
V271M |
probably benign |
Het |
| Agpat5 |
A |
G |
8: 18,896,739 (GRCm39) |
Y55C |
probably damaging |
Het |
| AI987944 |
A |
C |
7: 41,023,772 (GRCm39) |
Y402* |
probably null |
Het |
| Angptl4 |
C |
T |
17: 34,000,165 (GRCm39) |
A68T |
possibly damaging |
Het |
| Ankmy1 |
T |
C |
1: 92,814,531 (GRCm39) |
I325M |
probably benign |
Het |
| Arfgap2 |
A |
G |
2: 91,105,204 (GRCm39) |
K423E |
probably damaging |
Het |
| Arfgef3 |
A |
T |
10: 18,522,302 (GRCm39) |
S575T |
probably damaging |
Het |
| Arhgap24 |
A |
G |
5: 103,008,198 (GRCm39) |
I40V |
possibly damaging |
Het |
| Arhgef7 |
T |
C |
8: 11,869,733 (GRCm39) |
|
probably null |
Het |
| Arid1a |
C |
A |
4: 133,448,237 (GRCm39) |
S477I |
unknown |
Het |
| Armc7 |
T |
C |
11: 115,367,029 (GRCm39) |
V58A |
probably damaging |
Het |
| Arrdc5 |
A |
T |
17: 56,601,222 (GRCm39) |
I301N |
probably damaging |
Het |
| Capn15 |
G |
A |
17: 26,183,453 (GRCm39) |
P343S |
probably damaging |
Het |
| Catspere2 |
C |
T |
1: 177,843,495 (GRCm39) |
T69I |
possibly damaging |
Het |
| Ccdc39 |
T |
C |
3: 33,880,629 (GRCm39) |
K446R |
probably damaging |
Het |
| Cgn |
C |
T |
3: 94,670,535 (GRCm39) |
R1002Q |
probably damaging |
Het |
| Clstn3 |
A |
T |
6: 124,414,449 (GRCm39) |
I759N |
possibly damaging |
Het |
| Cops5 |
A |
G |
1: 10,104,243 (GRCm39) |
V166A |
possibly damaging |
Het |
| Cramp1 |
G |
T |
17: 25,191,323 (GRCm39) |
T1046K |
probably benign |
Het |
| Cthrc1 |
T |
G |
15: 38,950,072 (GRCm39) |
V143G |
probably damaging |
Het |
| Cul9 |
G |
A |
17: 46,849,490 (GRCm39) |
Q552* |
probably null |
Het |
| Cyp27b1 |
A |
T |
10: 126,886,957 (GRCm39) |
D391V |
probably damaging |
Het |
| Dcun1d2 |
A |
G |
8: 13,331,040 (GRCm39) |
L30S |
probably damaging |
Het |
| Dsc3 |
T |
C |
18: 20,120,091 (GRCm39) |
E189G |
probably damaging |
Het |
| Dst |
T |
G |
1: 34,193,675 (GRCm39) |
S295A |
probably damaging |
Het |
| Dusp22 |
A |
G |
13: 30,892,798 (GRCm39) |
T192A |
probably benign |
Het |
| Esp24 |
A |
T |
17: 39,349,176 (GRCm39) |
M1L |
probably null |
Het |
| Evc2 |
G |
A |
5: 37,550,541 (GRCm39) |
|
probably null |
Het |
| Fgd6 |
A |
G |
10: 93,880,694 (GRCm39) |
N516S |
probably benign |
Het |
| Fmn1 |
T |
C |
2: 113,426,714 (GRCm39) |
Y1144H |
probably damaging |
Het |
| Fut8 |
T |
A |
12: 77,495,448 (GRCm39) |
I346K |
possibly damaging |
Het |
| Gata3 |
A |
C |
2: 9,882,201 (GRCm39) |
V32G |
probably damaging |
Het |
| Glrb |
A |
T |
3: 80,819,282 (GRCm39) |
C39S |
possibly damaging |
Het |
| Gpr171 |
A |
G |
3: 59,005,016 (GRCm39) |
V253A |
probably benign |
Het |
| Hmgxb3 |
T |
C |
18: 61,266,980 (GRCm39) |
S1085G |
probably benign |
Het |
| Hspa4l |
A |
G |
3: 40,741,226 (GRCm39) |
N746S |
probably benign |
Het |
| Hyal5 |
A |
G |
6: 24,877,902 (GRCm39) |
T333A |
probably benign |
Het |
| Ippk |
T |
C |
13: 49,615,069 (GRCm39) |
V484A |
probably benign |
Het |
| Jmjd8 |
A |
T |
17: 26,048,266 (GRCm39) |
T33S |
possibly damaging |
Het |
| Kctd19 |
T |
A |
8: 106,113,694 (GRCm39) |
I660L |
possibly damaging |
Het |
| Lrat |
A |
G |
3: 82,810,649 (GRCm39) |
V124A |
probably benign |
Het |
| Madcam1 |
A |
G |
10: 79,502,358 (GRCm39) |
I281V |
probably benign |
Het |
| Mast2 |
T |
A |
4: 116,173,688 (GRCm39) |
I455F |
possibly damaging |
Het |
| Mroh7 |
A |
G |
4: 106,560,255 (GRCm39) |
L683P |
probably benign |
Het |
| Myo15b |
C |
A |
11: 115,777,683 (GRCm39) |
|
probably null |
Het |
| Ncam1 |
T |
C |
9: 49,416,849 (GRCm39) |
E814G |
probably benign |
Het |
| Ncoa3 |
A |
G |
2: 165,897,182 (GRCm39) |
T658A |
probably benign |
Het |
| Or13a20 |
T |
G |
7: 140,232,650 (GRCm39) |
Y253D |
probably damaging |
Het |
| Or9a2 |
T |
C |
6: 41,748,456 (GRCm39) |
Y259C |
possibly damaging |
Het |
| P2ry13 |
T |
C |
3: 59,116,939 (GRCm39) |
K280E |
probably damaging |
Het |
| Paqr8 |
C |
A |
1: 21,005,048 (GRCm39) |
F67L |
probably benign |
Het |
| Pfkfb3 |
G |
T |
2: 11,498,747 (GRCm39) |
R37S |
probably damaging |
Het |
| Phf14 |
A |
G |
6: 11,941,478 (GRCm39) |
D310G |
possibly damaging |
Het |
| Phkb |
A |
G |
8: 86,602,286 (GRCm39) |
S26G |
possibly damaging |
Het |
| Pkd1l2 |
T |
A |
8: 117,755,147 (GRCm39) |
I1684F |
probably damaging |
Het |
| Plod2 |
T |
C |
9: 92,488,637 (GRCm39) |
V621A |
probably benign |
Het |
| Plvap |
T |
C |
8: 71,964,116 (GRCm39) |
N82S |
probably damaging |
Het |
| Pomgnt2 |
A |
G |
9: 121,811,326 (GRCm39) |
V485A |
probably damaging |
Het |
| Psmd9 |
A |
G |
5: 123,366,410 (GRCm39) |
E14G |
probably benign |
Het |
| Pwwp2b |
A |
G |
7: 138,835,879 (GRCm39) |
E440G |
probably damaging |
Het |
| Rasgrp1 |
G |
A |
2: 117,113,100 (GRCm39) |
Q771* |
probably null |
Het |
| Rft1 |
C |
T |
14: 30,388,744 (GRCm39) |
Q223* |
probably null |
Het |
| Rgs22 |
C |
A |
15: 36,093,047 (GRCm39) |
V409F |
probably damaging |
Het |
| Rgsl1 |
G |
A |
1: 153,701,672 (GRCm39) |
P261S |
possibly damaging |
Het |
| Rpl7a |
A |
G |
2: 26,801,127 (GRCm39) |
N38S |
probably damaging |
Het |
| Sh3rf2 |
T |
A |
18: 42,187,004 (GRCm39) |
F41Y |
probably damaging |
Het |
| Spata6 |
T |
A |
4: 111,603,388 (GRCm39) |
S34R |
probably damaging |
Het |
| Sult2a3 |
A |
T |
7: 13,856,867 (GRCm39) |
Y18N |
probably benign |
Het |
| Tapt1 |
A |
G |
5: 44,375,444 (GRCm39) |
|
probably null |
Het |
| Tex2 |
A |
T |
11: 106,394,466 (GRCm39) |
C615S |
possibly damaging |
Het |
| Trim43b |
T |
C |
9: 88,969,665 (GRCm39) |
K261R |
possibly damaging |
Het |
| Unc5c |
T |
A |
3: 141,495,583 (GRCm39) |
M484K |
probably damaging |
Het |
| Vezf1 |
T |
A |
11: 87,964,573 (GRCm39) |
S242T |
probably damaging |
Het |
| Vmn2r1 |
A |
G |
3: 63,997,034 (GRCm39) |
Y230C |
probably damaging |
Het |
| Vmn2r94 |
A |
G |
17: 18,477,965 (GRCm39) |
S149P |
probably damaging |
Het |
| Wfdc1 |
T |
A |
8: 120,393,405 (GRCm39) |
|
probably null |
Het |
| Zfp975 |
T |
C |
7: 42,312,236 (GRCm39) |
T126A |
probably benign |
Het |
| Zmym4 |
T |
C |
4: 126,776,105 (GRCm39) |
|
probably null |
Het |
|
| Other mutations in Hdac5 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00815:Hdac5
|
APN |
11 |
102,088,168 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01614:Hdac5
|
APN |
11 |
102,090,854 (GRCm39) |
missense |
probably benign |
0.38 |
|
IGL01799:Hdac5
|
APN |
11 |
102,090,911 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
IGL02839:Hdac5
|
APN |
11 |
102,095,734 (GRCm39) |
missense |
probably damaging |
1.00 |
|
E0354:Hdac5
|
UTSW |
11 |
102,092,972 (GRCm39) |
unclassified |
probably benign |
|
|
R0544:Hdac5
|
UTSW |
11 |
102,086,922 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0612:Hdac5
|
UTSW |
11 |
102,087,078 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R0632:Hdac5
|
UTSW |
11 |
102,096,638 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0659:Hdac5
|
UTSW |
11 |
102,086,850 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0930:Hdac5
|
UTSW |
11 |
102,095,472 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1195:Hdac5
|
UTSW |
11 |
102,096,332 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1195:Hdac5
|
UTSW |
11 |
102,096,332 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1195:Hdac5
|
UTSW |
11 |
102,096,332 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1475:Hdac5
|
UTSW |
11 |
102,093,012 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R1596:Hdac5
|
UTSW |
11 |
102,095,482 (GRCm39) |
splice site |
probably null |
|
|
R1673:Hdac5
|
UTSW |
11 |
102,089,631 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1783:Hdac5
|
UTSW |
11 |
102,091,342 (GRCm39) |
missense |
probably benign |
|
|
R1932:Hdac5
|
UTSW |
11 |
102,086,698 (GRCm39) |
splice site |
probably benign |
|
|
R2197:Hdac5
|
UTSW |
11 |
102,095,340 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2348:Hdac5
|
UTSW |
11 |
102,090,840 (GRCm39) |
missense |
probably benign |
0.44 |
|
R2518:Hdac5
|
UTSW |
11 |
102,087,962 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3081:Hdac5
|
UTSW |
11 |
102,096,436 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3622:Hdac5
|
UTSW |
11 |
102,086,644 (GRCm39) |
missense |
probably benign |
0.34 |
|
R4543:Hdac5
|
UTSW |
11 |
102,104,770 (GRCm39) |
intron |
probably benign |
|
|
R4559:Hdac5
|
UTSW |
11 |
102,089,928 (GRCm39) |
unclassified |
probably benign |
|
|
R4661:Hdac5
|
UTSW |
11 |
102,096,675 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4682:Hdac5
|
UTSW |
11 |
102,097,456 (GRCm39) |
missense |
probably null |
0.99 |
|
R4708:Hdac5
|
UTSW |
11 |
102,093,019 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R4933:Hdac5
|
UTSW |
11 |
102,091,389 (GRCm39) |
unclassified |
probably benign |
|
|
R4957:Hdac5
|
UTSW |
11 |
102,096,082 (GRCm39) |
unclassified |
probably benign |
|
|
R4991:Hdac5
|
UTSW |
11 |
102,096,450 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5090:Hdac5
|
UTSW |
11 |
102,088,539 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5103:Hdac5
|
UTSW |
11 |
102,087,109 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5330:Hdac5
|
UTSW |
11 |
102,088,180 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5331:Hdac5
|
UTSW |
11 |
102,088,180 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5386:Hdac5
|
UTSW |
11 |
102,092,967 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R5449:Hdac5
|
UTSW |
11 |
102,086,923 (GRCm39) |
nonsense |
probably null |
|
|
R5682:Hdac5
|
UTSW |
11 |
102,104,749 (GRCm39) |
intron |
probably benign |
|
|
R6615:Hdac5
|
UTSW |
11 |
102,087,882 (GRCm39) |
splice site |
probably null |
|
|
R6705:Hdac5
|
UTSW |
11 |
102,092,062 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6875:Hdac5
|
UTSW |
11 |
102,093,102 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6952:Hdac5
|
UTSW |
11 |
102,095,786 (GRCm39) |
missense |
probably benign |
|
|
R7179:Hdac5
|
UTSW |
11 |
102,095,385 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R7368:Hdac5
|
UTSW |
11 |
102,088,207 (GRCm39) |
missense |
probably null |
1.00 |
|
R8140:Hdac5
|
UTSW |
11 |
102,088,181 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8151:Hdac5
|
UTSW |
11 |
102,097,294 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8684:Hdac5
|
UTSW |
11 |
102,096,147 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8719:Hdac5
|
UTSW |
11 |
102,097,963 (GRCm39) |
missense |
probably benign |
0.18 |
|
R8751:Hdac5
|
UTSW |
11 |
102,109,280 (GRCm39) |
missense |
probably benign |
0.19 |
|
R8893:Hdac5
|
UTSW |
11 |
102,097,512 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R9337:Hdac5
|
UTSW |
11 |
102,096,178 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9516:Hdac5
|
UTSW |
11 |
102,093,522 (GRCm39) |
missense |
probably benign |
0.08 |
|
R9595:Hdac5
|
UTSW |
11 |
102,096,129 (GRCm39) |
missense |
probably benign |
0.06 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGAAGTGAAGACCCCTTTCCCCTC -3'
(R):5'- ATCGTGTAAGAGATGGCAAGCCTG -3'
Sequencing Primer
(F):5'- CTCCGTGCAGTTTTGCTAAG -3'
(R):5'- TTCAGACTGAGCCTTACGCAG -3'
|
| Posted On |
2014-03-28 |
Incidental Mutation