Incidental Mutation 'R1467:Ipo9'
| ID |
164532 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ipo9
|
| Ensembl Gene |
ENSMUSG00000041879 |
| Gene Name |
importin 9 |
| Synonyms |
0710008K06Rik, Imp9 |
| MMRRC Submission |
039520-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R1467 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
1 |
| Chromosomal Location |
135310050-135358237 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 135334281 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamic Acid to Glycine
at position 315
(E315G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000124779
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000041023]
[ENSMUST00000161032]
[ENSMUST00000161189]
[ENSMUST00000161838]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000041023
AA Change: E315G
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000036093
Gene: ENSMUSG00000041879
AA Change: E315G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
10 |
N/A |
INTRINSIC |
|
IBN_N
|
43 |
119 |
3.83e-7 |
SMART |
|
low complexity region
|
911 |
922 |
N/A |
INTRINSIC |
|
low complexity region
|
978 |
990 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000159017
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000159173
|
| SMART Domains |
Protein: ENSMUSP00000123869
Gene: ENSMUSG00000041879
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
1 |
7 |
N/A |
INTRINSIC |
|
SCOP:d1i6la_
|
18 |
49 |
3e-3 |
SMART |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000161032
AA Change: E315G
PolyPhen 2
Score 0.888 (Sensitivity: 0.82; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000124779
Gene: ENSMUSG00000041879
AA Change: E315G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
10 |
N/A |
INTRINSIC |
|
IBN_N
|
43 |
119 |
3.83e-7 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000161135
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000161189
|
| SMART Domains |
Protein: ENSMUSP00000124492
Gene: ENSMUSG00000041879
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
10 |
N/A |
INTRINSIC |
|
SCOP:d1i6la_
|
21 |
52 |
4e-3 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000161258
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000161704
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000187450
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000161838
|
| SMART Domains |
Protein: ENSMUSP00000125646
Gene: ENSMUSG00000041879
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
10 |
N/A |
INTRINSIC |
|
SCOP:d1i6la_
|
21 |
52 |
4e-3 |
SMART |
|
| Meta Mutation Damage Score |
0.1425 |
| Coding Region Coverage |
- 1x: 99.6%
- 3x: 98.1%
- 10x: 88.5%
- 20x: 62.9%
|
| Validation Efficiency |
|
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a transgenic gene disruption exhibit embryonic lethality at E7. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 98 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2010315B03Rik |
C |
A |
9: 124,058,093 (GRCm39) |
V9L |
possibly damaging |
Het |
| A630010A05Rik |
C |
A |
16: 14,436,447 (GRCm39) |
L167I |
possibly damaging |
Het |
| Abca14 |
A |
T |
7: 119,815,405 (GRCm39) |
M218L |
possibly damaging |
Het |
| Abca15 |
C |
A |
7: 119,939,761 (GRCm39) |
|
probably null |
Het |
| Acod1 |
T |
C |
14: 103,292,003 (GRCm39) |
F176L |
probably benign |
Het |
| Actr5 |
A |
G |
2: 158,480,617 (GRCm39) |
H545R |
probably benign |
Het |
| Adcy1 |
A |
G |
11: 7,088,396 (GRCm39) |
T472A |
probably damaging |
Het |
| Aldh1l1 |
A |
G |
6: 90,548,910 (GRCm39) |
K469R |
possibly damaging |
Het |
| Ambra1 |
A |
T |
2: 91,716,048 (GRCm39) |
Q853L |
probably damaging |
Het |
| Apol7e |
G |
T |
15: 77,601,966 (GRCm39) |
G188V |
probably damaging |
Het |
| AU018091 |
A |
T |
7: 3,214,089 (GRCm39) |
W43R |
probably benign |
Het |
| Baat |
A |
G |
4: 49,503,101 (GRCm39) |
V7A |
probably benign |
Het |
| Bcas1 |
C |
A |
2: 170,229,852 (GRCm39) |
Q249H |
possibly damaging |
Het |
| Bltp1 |
T |
A |
3: 37,090,094 (GRCm39) |
V676D |
probably damaging |
Het |
| Bptf |
G |
T |
11: 106,945,881 (GRCm39) |
Q2453K |
possibly damaging |
Het |
| Btg3 |
A |
G |
16: 78,161,688 (GRCm39) |
|
probably null |
Het |
| Cacna2d3 |
T |
C |
14: 29,055,736 (GRCm39) |
N298S |
possibly damaging |
Het |
| Carf |
G |
A |
1: 60,167,152 (GRCm39) |
V127I |
possibly damaging |
Het |
| Catsperg1 |
T |
C |
7: 28,884,433 (GRCm39) |
S916G |
probably damaging |
Het |
| Cers1 |
T |
C |
8: 70,775,819 (GRCm39) |
S274P |
possibly damaging |
Het |
| Ces4a |
T |
A |
8: 105,864,667 (GRCm39) |
V48E |
possibly damaging |
Het |
| Cfap54 |
T |
A |
10: 92,805,625 (GRCm39) |
H1495L |
probably benign |
Het |
| Cntnap5a |
T |
A |
1: 115,612,898 (GRCm39) |
L11* |
probably null |
Het |
| Cr2 |
C |
T |
1: 194,839,817 (GRCm39) |
G913R |
probably damaging |
Het |
| Cul9 |
A |
G |
17: 46,836,299 (GRCm39) |
L1155P |
probably damaging |
Het |
| Dlec1 |
A |
T |
9: 118,971,646 (GRCm39) |
D1278V |
probably damaging |
Het |
| Dmrt2 |
A |
G |
19: 25,650,970 (GRCm39) |
E52G |
possibly damaging |
Het |
| Dsp |
A |
G |
13: 38,376,688 (GRCm39) |
K1491R |
probably benign |
Het |
| Ecpas |
A |
G |
4: 58,832,753 (GRCm39) |
V869A |
probably benign |
Het |
| Eef1d |
A |
T |
15: 75,767,770 (GRCm39) |
D206E |
probably damaging |
Het |
| Erbb2 |
C |
T |
11: 98,327,001 (GRCm39) |
Q1137* |
probably null |
Het |
| Ercc2 |
T |
A |
7: 19,119,811 (GRCm39) |
D157E |
probably benign |
Het |
| Eri1 |
A |
G |
8: 35,936,284 (GRCm39) |
*346Q |
probably null |
Het |
| Espl1 |
A |
G |
15: 102,228,293 (GRCm39) |
E1689G |
probably benign |
Het |
| Fap |
C |
T |
2: 62,347,964 (GRCm39) |
V539I |
probably benign |
Het |
| Fasn |
A |
G |
11: 120,701,866 (GRCm39) |
F1871S |
probably benign |
Het |
| Gabpb1 |
T |
G |
2: 126,494,247 (GRCm39) |
Y126S |
probably damaging |
Het |
| Grm1 |
T |
C |
10: 10,595,702 (GRCm39) |
Y642C |
probably damaging |
Het |
| Heatr4 |
T |
C |
12: 84,024,841 (GRCm39) |
T327A |
possibly damaging |
Het |
| Hmbox1 |
T |
C |
14: 65,099,027 (GRCm39) |
D212G |
possibly damaging |
Het |
| Hmcn1 |
T |
A |
1: 150,565,341 (GRCm39) |
D2262V |
probably damaging |
Het |
| Hoxb9 |
A |
G |
11: 96,162,764 (GRCm39) |
T133A |
probably benign |
Het |
| Insr |
A |
T |
8: 3,219,720 (GRCm39) |
V934E |
probably damaging |
Het |
| Itga10 |
C |
T |
3: 96,559,545 (GRCm39) |
Q481* |
probably null |
Het |
| Kntc1 |
T |
A |
5: 123,925,047 (GRCm39) |
M1120K |
probably benign |
Het |
| Krt78 |
A |
G |
15: 101,854,728 (GRCm39) |
Y1028H |
possibly damaging |
Het |
| Lrrc38 |
A |
T |
4: 143,096,450 (GRCm39) |
I254F |
probably damaging |
Het |
| Lyrm7 |
A |
G |
11: 54,741,215 (GRCm39) |
F40L |
probably damaging |
Het |
| Mfsd4b1 |
C |
T |
10: 39,878,631 (GRCm39) |
S422N |
possibly damaging |
Het |
| Mlh3 |
A |
T |
12: 85,284,374 (GRCm39) |
L1380* |
probably null |
Het |
| Mrpl24 |
C |
A |
3: 87,829,744 (GRCm39) |
A110D |
probably benign |
Het |
| Mrps14 |
T |
C |
1: 160,024,520 (GRCm39) |
V17A |
probably benign |
Het |
| Mtcl1 |
T |
C |
17: 66,755,322 (GRCm39) |
D340G |
probably damaging |
Het |
| Neb |
T |
C |
2: 52,120,059 (GRCm39) |
Y3900C |
probably damaging |
Het |
| Neurod4 |
T |
C |
10: 130,106,473 (GRCm39) |
D267G |
probably benign |
Het |
| Nf1 |
A |
T |
11: 79,319,452 (GRCm39) |
I536F |
possibly damaging |
Het |
| Nkg7 |
C |
T |
7: 43,086,857 (GRCm39) |
P44S |
probably damaging |
Het |
| Or14c40 |
T |
C |
7: 86,313,185 (GRCm39) |
V105A |
possibly damaging |
Het |
| Or4a67 |
T |
C |
2: 88,597,832 (GRCm39) |
I276V |
probably benign |
Het |
| Pcif1 |
T |
C |
2: 164,731,058 (GRCm39) |
Y404H |
probably benign |
Het |
| Pcnx2 |
A |
T |
8: 126,480,289 (GRCm39) |
L2006Q |
possibly damaging |
Het |
| Pcnx3 |
A |
T |
19: 5,724,922 (GRCm39) |
S821T |
possibly damaging |
Het |
| Pde8b |
T |
A |
13: 95,170,680 (GRCm39) |
D662V |
probably damaging |
Het |
| Pkd1l3 |
C |
T |
8: 110,343,000 (GRCm39) |
P113S |
unknown |
Het |
| Pkd2l1 |
G |
T |
19: 44,142,648 (GRCm39) |
Q465K |
possibly damaging |
Het |
| Plch2 |
G |
T |
4: 155,068,189 (GRCm39) |
P1479Q |
probably benign |
Het |
| Plekhm3 |
A |
T |
1: 64,932,041 (GRCm39) |
I521N |
probably damaging |
Het |
| Pola2 |
A |
T |
19: 5,992,093 (GRCm39) |
Y526* |
probably null |
Het |
| Prss23 |
T |
C |
7: 89,159,217 (GRCm39) |
D284G |
probably damaging |
Het |
| Psme2b |
A |
G |
11: 48,836,467 (GRCm39) |
F160S |
probably damaging |
Het |
| Rap1gap2 |
A |
G |
11: 74,327,853 (GRCm39) |
V139A |
possibly damaging |
Het |
| Rbbp9 |
G |
T |
2: 144,385,777 (GRCm39) |
R163S |
possibly damaging |
Het |
| Rdh12 |
T |
C |
12: 79,260,522 (GRCm39) |
L206P |
probably damaging |
Het |
| Rhou |
T |
C |
8: 124,388,029 (GRCm39) |
W254R |
possibly damaging |
Het |
| Scfd1 |
A |
G |
12: 51,478,281 (GRCm39) |
K498E |
possibly damaging |
Het |
| Scn7a |
A |
G |
2: 66,519,902 (GRCm39) |
Y1001H |
probably benign |
Het |
| Setx |
T |
A |
2: 29,048,917 (GRCm39) |
V1981E |
probably damaging |
Het |
| Sfxn1 |
T |
C |
13: 54,247,890 (GRCm39) |
I205T |
possibly damaging |
Het |
| Shld2 |
G |
T |
14: 33,990,619 (GRCm39) |
H96N |
possibly damaging |
Het |
| Speer1g |
C |
T |
5: 11,180,337 (GRCm39) |
H82Y |
probably damaging |
Het |
| Spock1 |
G |
A |
13: 57,577,182 (GRCm39) |
R416C |
possibly damaging |
Het |
| Spred2 |
A |
G |
11: 19,968,109 (GRCm39) |
I222V |
probably benign |
Het |
| Stkld1 |
A |
T |
2: 26,839,407 (GRCm39) |
T358S |
probably benign |
Het |
| Strip1 |
T |
C |
3: 107,534,724 (GRCm39) |
E102G |
possibly damaging |
Het |
| Tars3 |
T |
C |
7: 65,305,444 (GRCm39) |
S223P |
probably damaging |
Het |
| Tdpoz1 |
T |
A |
3: 93,578,637 (GRCm39) |
E49V |
probably benign |
Het |
| Tert |
A |
G |
13: 73,776,328 (GRCm39) |
T360A |
probably benign |
Het |
| Tspear |
A |
G |
10: 77,717,026 (GRCm39) |
Y567C |
probably damaging |
Het |
| Ttc28 |
A |
G |
5: 111,433,254 (GRCm39) |
Q2096R |
probably benign |
Het |
| Ugt2b38 |
T |
G |
5: 87,560,232 (GRCm39) |
N361H |
probably damaging |
Het |
| Unc80 |
C |
T |
1: 66,560,740 (GRCm39) |
H823Y |
possibly damaging |
Het |
| Vmn2r111 |
T |
A |
17: 22,790,028 (GRCm39) |
H326L |
probably damaging |
Het |
| Vmn2r18 |
A |
G |
5: 151,510,301 (GRCm39) |
F24S |
possibly damaging |
Het |
| Vmn2r82 |
A |
T |
10: 79,232,133 (GRCm39) |
I711F |
probably benign |
Het |
| Vwa8 |
C |
T |
14: 79,341,134 (GRCm39) |
Q1537* |
probably null |
Het |
| Wdr64 |
G |
A |
1: 175,603,288 (GRCm39) |
V630I |
probably benign |
Het |
| Wnt6 |
G |
T |
1: 74,821,434 (GRCm39) |
W84L |
probably damaging |
Het |
| Zfp11 |
C |
A |
5: 129,735,254 (GRCm39) |
R69L |
probably benign |
Het |
|
| Other mutations in Ipo9 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00896:Ipo9
|
APN |
1 |
135,327,797 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01611:Ipo9
|
APN |
1 |
135,314,431 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
IGL01941:Ipo9
|
APN |
1 |
135,335,811 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL01944:Ipo9
|
APN |
1 |
135,333,624 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01959:Ipo9
|
APN |
1 |
135,348,093 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
IGL02649:Ipo9
|
APN |
1 |
135,313,672 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL02697:Ipo9
|
APN |
1 |
135,318,314 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03286:Ipo9
|
APN |
1 |
135,334,816 (GRCm39) |
intron |
probably benign |
|
|
FR4304:Ipo9
|
UTSW |
1 |
135,314,017 (GRCm39) |
nonsense |
probably null |
|
|
FR4304:Ipo9
|
UTSW |
1 |
135,314,013 (GRCm39) |
small insertion |
probably benign |
|
|
FR4340:Ipo9
|
UTSW |
1 |
135,314,009 (GRCm39) |
small insertion |
probably benign |
|
|
FR4340:Ipo9
|
UTSW |
1 |
135,314,007 (GRCm39) |
small insertion |
probably benign |
|
|
FR4548:Ipo9
|
UTSW |
1 |
135,314,013 (GRCm39) |
small insertion |
probably benign |
|
|
FR4589:Ipo9
|
UTSW |
1 |
135,314,019 (GRCm39) |
small insertion |
probably benign |
|
|
FR4589:Ipo9
|
UTSW |
1 |
135,314,004 (GRCm39) |
small insertion |
probably benign |
|
|
FR4976:Ipo9
|
UTSW |
1 |
135,314,019 (GRCm39) |
small insertion |
probably benign |
|
|
R0111:Ipo9
|
UTSW |
1 |
135,333,662 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R0238:Ipo9
|
UTSW |
1 |
135,332,074 (GRCm39) |
splice site |
probably benign |
|
|
R0239:Ipo9
|
UTSW |
1 |
135,332,074 (GRCm39) |
splice site |
probably benign |
|
|
R0279:Ipo9
|
UTSW |
1 |
135,348,101 (GRCm39) |
intron |
probably benign |
|
|
R0704:Ipo9
|
UTSW |
1 |
135,314,006 (GRCm39) |
small deletion |
probably benign |
|
|
R1070:Ipo9
|
UTSW |
1 |
135,334,281 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1282:Ipo9
|
UTSW |
1 |
135,330,030 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R1467:Ipo9
|
UTSW |
1 |
135,334,281 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1728:Ipo9
|
UTSW |
1 |
135,329,988 (GRCm39) |
missense |
probably benign |
|
|
R1728:Ipo9
|
UTSW |
1 |
135,314,009 (GRCm39) |
small insertion |
probably benign |
|
|
R1728:Ipo9
|
UTSW |
1 |
135,314,006 (GRCm39) |
small insertion |
probably benign |
|
|
R1729:Ipo9
|
UTSW |
1 |
135,329,988 (GRCm39) |
missense |
probably benign |
|
|
R1729:Ipo9
|
UTSW |
1 |
135,314,006 (GRCm39) |
small insertion |
probably benign |
|
|
R1730:Ipo9
|
UTSW |
1 |
135,329,988 (GRCm39) |
missense |
probably benign |
|
|
R1730:Ipo9
|
UTSW |
1 |
135,314,006 (GRCm39) |
small insertion |
probably benign |
|
|
R1739:Ipo9
|
UTSW |
1 |
135,329,988 (GRCm39) |
missense |
probably benign |
|
|
R1739:Ipo9
|
UTSW |
1 |
135,314,006 (GRCm39) |
small insertion |
probably benign |
|
|
R1762:Ipo9
|
UTSW |
1 |
135,314,006 (GRCm39) |
small insertion |
probably benign |
|
|
R1762:Ipo9
|
UTSW |
1 |
135,329,988 (GRCm39) |
missense |
probably benign |
|
|
R1783:Ipo9
|
UTSW |
1 |
135,314,006 (GRCm39) |
small insertion |
probably benign |
|
|
R1783:Ipo9
|
UTSW |
1 |
135,329,988 (GRCm39) |
missense |
probably benign |
|
|
R1784:Ipo9
|
UTSW |
1 |
135,314,006 (GRCm39) |
small insertion |
probably benign |
|
|
R1784:Ipo9
|
UTSW |
1 |
135,329,988 (GRCm39) |
missense |
probably benign |
|
|
R1785:Ipo9
|
UTSW |
1 |
135,314,006 (GRCm39) |
small insertion |
probably benign |
|
|
R1785:Ipo9
|
UTSW |
1 |
135,314,019 (GRCm39) |
small insertion |
probably benign |
|
|
R1785:Ipo9
|
UTSW |
1 |
135,329,988 (GRCm39) |
missense |
probably benign |
|
|
R1899:Ipo9
|
UTSW |
1 |
135,327,884 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2049:Ipo9
|
UTSW |
1 |
135,314,006 (GRCm39) |
small insertion |
probably benign |
|
|
R2049:Ipo9
|
UTSW |
1 |
135,329,988 (GRCm39) |
missense |
probably benign |
|
|
R2130:Ipo9
|
UTSW |
1 |
135,314,006 (GRCm39) |
small insertion |
probably benign |
|
|
R2130:Ipo9
|
UTSW |
1 |
135,329,988 (GRCm39) |
missense |
probably benign |
|
|
R2131:Ipo9
|
UTSW |
1 |
135,314,006 (GRCm39) |
small insertion |
probably benign |
|
|
R2131:Ipo9
|
UTSW |
1 |
135,329,988 (GRCm39) |
missense |
probably benign |
|
|
R2133:Ipo9
|
UTSW |
1 |
135,314,006 (GRCm39) |
small insertion |
probably benign |
|
|
R2133:Ipo9
|
UTSW |
1 |
135,314,013 (GRCm39) |
small insertion |
probably benign |
|
|
R2133:Ipo9
|
UTSW |
1 |
135,329,988 (GRCm39) |
missense |
probably benign |
|
|
R2136:Ipo9
|
UTSW |
1 |
135,322,023 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2141:Ipo9
|
UTSW |
1 |
135,329,988 (GRCm39) |
missense |
probably benign |
|
|
R2141:Ipo9
|
UTSW |
1 |
135,314,006 (GRCm39) |
small insertion |
probably benign |
|
|
R2142:Ipo9
|
UTSW |
1 |
135,314,020 (GRCm39) |
small insertion |
probably benign |
|
|
R2142:Ipo9
|
UTSW |
1 |
135,329,988 (GRCm39) |
missense |
probably benign |
|
|
R2142:Ipo9
|
UTSW |
1 |
135,314,006 (GRCm39) |
small insertion |
probably benign |
|
|
R2142:Ipo9
|
UTSW |
1 |
135,314,013 (GRCm39) |
small insertion |
probably benign |
|
|
R2356:Ipo9
|
UTSW |
1 |
135,334,555 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2923:Ipo9
|
UTSW |
1 |
135,327,867 (GRCm39) |
missense |
probably benign |
0.25 |
|
R3161:Ipo9
|
UTSW |
1 |
135,337,214 (GRCm39) |
missense |
probably benign |
0.43 |
|
R3162:Ipo9
|
UTSW |
1 |
135,337,214 (GRCm39) |
missense |
probably benign |
0.43 |
|
R3162:Ipo9
|
UTSW |
1 |
135,337,214 (GRCm39) |
missense |
probably benign |
0.43 |
|
R4086:Ipo9
|
UTSW |
1 |
135,316,428 (GRCm39) |
unclassified |
probably benign |
|
|
R4679:Ipo9
|
UTSW |
1 |
135,321,907 (GRCm39) |
missense |
probably benign |
|
|
R4816:Ipo9
|
UTSW |
1 |
135,334,288 (GRCm39) |
missense |
probably benign |
0.21 |
|
R4956:Ipo9
|
UTSW |
1 |
135,331,960 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5052:Ipo9
|
UTSW |
1 |
135,316,349 (GRCm39) |
splice site |
probably null |
|
|
R5055:Ipo9
|
UTSW |
1 |
135,330,097 (GRCm39) |
nonsense |
probably null |
|
|
R5230:Ipo9
|
UTSW |
1 |
135,347,808 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5240:Ipo9
|
UTSW |
1 |
135,317,344 (GRCm39) |
unclassified |
probably benign |
|
|
R5257:Ipo9
|
UTSW |
1 |
135,313,173 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5340:Ipo9
|
UTSW |
1 |
135,313,170 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5560:Ipo9
|
UTSW |
1 |
135,329,983 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5602:Ipo9
|
UTSW |
1 |
135,329,983 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5604:Ipo9
|
UTSW |
1 |
135,329,983 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5654:Ipo9
|
UTSW |
1 |
135,313,210 (GRCm39) |
nonsense |
probably null |
|
|
R6018:Ipo9
|
UTSW |
1 |
135,318,274 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6128:Ipo9
|
UTSW |
1 |
135,318,311 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R6841:Ipo9
|
UTSW |
1 |
135,314,046 (GRCm39) |
missense |
probably benign |
|
|
R7230:Ipo9
|
UTSW |
1 |
135,334,496 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R7255:Ipo9
|
UTSW |
1 |
135,313,726 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7383:Ipo9
|
UTSW |
1 |
135,316,411 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7844:Ipo9
|
UTSW |
1 |
135,322,062 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7889:Ipo9
|
UTSW |
1 |
135,334,591 (GRCm39) |
missense |
probably benign |
0.22 |
|
R8125:Ipo9
|
UTSW |
1 |
135,331,078 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8823:Ipo9
|
UTSW |
1 |
135,347,077 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8889:Ipo9
|
UTSW |
1 |
135,314,544 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R8892:Ipo9
|
UTSW |
1 |
135,314,544 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R8906:Ipo9
|
UTSW |
1 |
135,321,951 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8926:Ipo9
|
UTSW |
1 |
135,313,952 (GRCm39) |
splice site |
probably benign |
|
|
R9084:Ipo9
|
UTSW |
1 |
135,334,563 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9215:Ipo9
|
UTSW |
1 |
135,347,033 (GRCm39) |
missense |
probably benign |
0.05 |
|
R9756:Ipo9
|
UTSW |
1 |
135,314,057 (GRCm39) |
missense |
probably benign |
0.00 |
|
Y5405:Ipo9
|
UTSW |
1 |
135,314,022 (GRCm39) |
small insertion |
probably benign |
|
|
Y5405:Ipo9
|
UTSW |
1 |
135,314,013 (GRCm39) |
small insertion |
probably benign |
|
|
Y5405:Ipo9
|
UTSW |
1 |
135,314,007 (GRCm39) |
small insertion |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- AGGCTACCATCATGTGGGACTTCG -3'
(R):5'- TCCTTTCCTGAGAACCCAGAGGAC -3'
Sequencing Primer
(F):5'- GCTGTATCAGACATCTGTGACAC -3'
(R):5'- CACTGCCTAACACTGGGG -3'
|
| Posted On |
2014-03-28 |
Incidental Mutation