Incidental Mutation 'IGL00155:4933402N22Rik'
ID1673
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol 4933402N22Rik
Ensembl Gene ENSMUSG00000067848
Gene NameRIKEN cDNA 4933402N22 gene
Synonyms
Accession Numbers
Is this an essential gene? Not available question?
Stock #IGL00155
Quality Score
Status
Chromosome5
Chromosomal Location11918043-11922821 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to G at 11921410 bp
ZygosityHeterozygous
Amino Acid Change Serine to Glycine at position 110 (S110G)
Ref Sequence ENSEMBL: ENSMUSP00000130317 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000170301]
Predicted Effect unknown
Transcript: ENSMUST00000168329
AA Change: S142G
SMART Domains Protein: ENSMUSP00000130833
Gene: ENSMUSG00000067848
AA Change: S142G

DomainStartEndE-ValueType
Pfam:Takusan 39 125 5.2e-25 PFAM
Predicted Effect possibly damaging
Transcript: ENSMUST00000170301
AA Change: S110G

PolyPhen 2 Score 0.845 (Sensitivity: 0.83; Specificity: 0.93)
SMART Domains Protein: ENSMUSP00000130317
Gene: ENSMUSG00000067848
AA Change: S110G

DomainStartEndE-ValueType
Pfam:Takusan 6 92 1e-24 PFAM
Predicted Effect noncoding transcript
Transcript: ENSMUST00000200042
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 38 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Aacs T C 5: 125,513,171 F498S probably damaging Het
Arhgap11a A G 2: 113,834,256 S561P probably benign Het
Best3 T C 10: 116,988,727 Y33H probably damaging Het
Cd209b T A 8: 3,919,945 probably benign Het
Cep152 A G 2: 125,563,888 S1575P probably benign Het
Crabp2 A G 3: 87,952,199 Y52C probably damaging Het
Crybg1 T C 10: 43,992,509 D1017G probably damaging Het
Ctnna2 A T 6: 76,980,761 W137R probably damaging Het
Cxcl9 T A 5: 92,323,869 H104L possibly damaging Het
Ddr2 A G 1: 169,984,427 I742T possibly damaging Het
Frem1 A G 4: 82,959,389 V223A possibly damaging Het
Fzd10 T A 5: 128,601,528 I104N probably damaging Het
Greb1 A G 12: 16,711,961 S473P probably damaging Het
Gtf2i T C 5: 134,242,748 Y873C probably damaging Het
Igsf6 T A 7: 121,070,653 K89* probably null Het
Ints3 A G 3: 90,406,329 F331L probably damaging Het
Kcnh3 A T 15: 99,242,473 H1080L possibly damaging Het
Mettl15 A T 2: 109,093,176 Y300* probably null Het
Mms19 A G 19: 41,948,233 F654L probably benign Het
Myc A G 15: 61,989,820 H425R probably benign Het
Ntn1 G T 11: 68,226,619 probably benign Het
Ormdl2 C A 10: 128,820,075 G69W probably damaging Het
Pdpr T C 8: 111,102,072 V69A possibly damaging Het
Rbbp6 T C 7: 122,988,685 I254T probably damaging Het
Sema6d A G 2: 124,659,865 R543G possibly damaging Het
Slc18a1 C T 8: 69,051,346 A314T probably damaging Het
Slc22a26 A G 19: 7,782,836 L514P probably damaging Het
Slc22a28 A C 19: 8,130,203 S167A possibly damaging Het
Tchh A G 3: 93,445,299 E682G unknown Het
Thbs2 A T 17: 14,668,835 M1134K probably damaging Het
Tmem26 A G 10: 68,775,354 S218G probably damaging Het
Tmprss11c A T 5: 86,239,395 S208R probably benign Het
Tnfrsf8 T C 4: 145,292,591 probably null Het
Ush2a T C 1: 188,864,678 S3872P probably benign Het
Vmn1r69 T C 7: 10,579,952 N205S probably benign Het
Vmn2r54 T A 7: 12,631,913 probably benign Het
Wwtr1 A T 3: 57,463,521 M328K possibly damaging Het
Zfp64 G A 2: 168,926,681 S337L probably benign Het
Other mutations in 4933402N22Rik
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01904:4933402N22Rik APN 5 11921456 missense probably benign 0.06
R6029:4933402N22Rik UTSW 5 11920713 missense probably damaging 0.99
R6575:4933402N22Rik UTSW 5 11920645 nonsense probably null
R7238:4933402N22Rik UTSW 5 11920745 missense
Posted On2011-07-12