Incidental Mutation 'R1522:Nup210'
| ID |
167518 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Nup210
|
| Ensembl Gene |
ENSMUSG00000030091 |
| Gene Name |
nucleoporin 210 |
| Synonyms |
gp190, gp210, Pom210 |
| MMRRC Submission |
040871-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R1522 (G1)
|
| Quality Score |
193 |
|
Status
|
Not validated
|
| Chromosome |
6 |
| Chromosomal Location |
90990050-91093811 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to A
at 91046148 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Proline to Leucine
at position 595
(P595L)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000032179
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000032179]
[ENSMUST00000113509]
|
| AlphaFold |
Q9QY81 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000032179
AA Change: P595L
PolyPhen 2
Score 0.845 (Sensitivity: 0.83; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000032179
Gene: ENSMUSG00000030091
AA Change: P595L
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
25 |
N/A |
INTRINSIC |
|
Blast:BID_2
|
450 |
527 |
3e-29 |
BLAST |
|
low complexity region
|
850 |
862 |
N/A |
INTRINSIC |
|
Blast:S1
|
937 |
1022 |
6e-37 |
BLAST |
|
BID_2
|
1077 |
1152 |
8.36e-6 |
SMART |
|
low complexity region
|
1159 |
1168 |
N/A |
INTRINSIC |
|
Blast:BID_2
|
1468 |
1551 |
3e-35 |
BLAST |
|
transmembrane domain
|
1809 |
1831 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000113509
AA Change: P595L
PolyPhen 2
Score 0.638 (Sensitivity: 0.87; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000109137
Gene: ENSMUSG00000030091
AA Change: P595L
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
25 |
N/A |
INTRINSIC |
|
Blast:BID_2
|
450 |
527 |
4e-29 |
BLAST |
|
low complexity region
|
806 |
818 |
N/A |
INTRINSIC |
|
Blast:S1
|
893 |
978 |
4e-37 |
BLAST |
|
BID_2
|
1033 |
1108 |
8.36e-6 |
SMART |
|
low complexity region
|
1115 |
1124 |
N/A |
INTRINSIC |
|
Blast:BID_2
|
1424 |
1507 |
3e-35 |
BLAST |
|
transmembrane domain
|
1765 |
1787 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000151437
|
| Coding Region Coverage |
- 1x: 99.0%
- 3x: 98.1%
- 10x: 95.8%
- 20x: 91.1%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene is a membrane-spanning glycoprotein that is a major component of the nuclear pore complex. Multiple pseudogenes related to this gene are located on chromosome 3. [provided by RefSeq, Jul 2013]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 99 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700003E16Rik |
T |
C |
6: 83,139,568 (GRCm39) |
S498P |
probably damaging |
Het |
| 3100002H09Rik |
A |
G |
4: 124,504,487 (GRCm39) |
W22R |
probably damaging |
Het |
| AA986860 |
A |
G |
1: 130,670,831 (GRCm39) |
E351G |
probably damaging |
Het |
| Acsl5 |
T |
C |
19: 55,268,924 (GRCm39) |
V195A |
probably benign |
Het |
| Actmap |
A |
G |
7: 26,902,105 (GRCm39) |
H244R |
probably damaging |
Het |
| Adamts10 |
A |
G |
17: 33,756,293 (GRCm39) |
D312G |
probably benign |
Het |
| Adgrb1 |
A |
G |
15: 74,452,466 (GRCm39) |
M211V |
probably damaging |
Het |
| Ankfy1 |
C |
T |
11: 72,646,693 (GRCm39) |
R859* |
probably null |
Het |
| Atp8b1 |
T |
A |
18: 64,683,503 (GRCm39) |
I742L |
probably benign |
Het |
| B3galnt2 |
T |
A |
13: 14,145,354 (GRCm39) |
V89E |
probably damaging |
Het |
| Brinp3 |
A |
C |
1: 146,777,628 (GRCm39) |
T692P |
probably damaging |
Het |
| C9 |
T |
A |
15: 6,516,243 (GRCm39) |
F349I |
probably damaging |
Het |
| Cacna1a |
T |
A |
8: 85,360,062 (GRCm39) |
M1976K |
probably benign |
Het |
| Castor2 |
T |
G |
5: 134,154,726 (GRCm39) |
S43R |
probably damaging |
Het |
| Ccdc180 |
T |
C |
4: 45,927,975 (GRCm39) |
V1170A |
possibly damaging |
Het |
| Celsr1 |
A |
G |
15: 85,815,477 (GRCm39) |
V1846A |
probably benign |
Het |
| Ces1f |
A |
T |
8: 93,998,517 (GRCm39) |
Y160N |
possibly damaging |
Het |
| Cfap45 |
A |
G |
1: 172,368,139 (GRCm39) |
E377G |
probably damaging |
Het |
| Clca3a1 |
T |
A |
3: 144,460,932 (GRCm39) |
M240L |
probably benign |
Het |
| Clnk |
G |
A |
5: 38,952,309 (GRCm39) |
T10M |
probably damaging |
Het |
| Cntrl |
T |
A |
2: 35,045,291 (GRCm39) |
I781K |
possibly damaging |
Het |
| Col11a2 |
G |
A |
17: 34,274,228 (GRCm39) |
G375S |
probably damaging |
Het |
| Col6a5 |
T |
A |
9: 105,817,193 (GRCm39) |
I373F |
unknown |
Het |
| Dmxl1 |
C |
T |
18: 49,985,434 (GRCm39) |
A227V |
probably benign |
Het |
| Dok5 |
A |
G |
2: 170,574,052 (GRCm39) |
N4D |
probably benign |
Het |
| Dpysl3 |
A |
T |
18: 43,496,622 (GRCm39) |
V138D |
probably damaging |
Het |
| Efs |
A |
T |
14: 55,157,172 (GRCm39) |
Y380N |
probably damaging |
Het |
| Eme2 |
G |
A |
17: 25,111,892 (GRCm39) |
S263F |
probably damaging |
Het |
| Farp2 |
A |
G |
1: 93,546,275 (GRCm39) |
Q855R |
possibly damaging |
Het |
| Fcrl2 |
A |
C |
3: 87,164,014 (GRCm39) |
S372A |
possibly damaging |
Het |
| Gadl1 |
C |
T |
9: 115,773,297 (GRCm39) |
A113V |
probably damaging |
Het |
| Gda |
T |
A |
19: 21,389,903 (GRCm39) |
E219D |
probably benign |
Het |
| Gli1 |
A |
T |
10: 127,168,446 (GRCm39) |
M469K |
probably damaging |
Het |
| Gm4847 |
A |
T |
1: 166,469,219 (GRCm39) |
S148R |
probably damaging |
Het |
| Golga2 |
T |
C |
2: 32,192,216 (GRCm39) |
V325A |
probably benign |
Het |
| Hpf1 |
A |
G |
8: 61,349,783 (GRCm39) |
D137G |
probably damaging |
Het |
| Htr2a |
C |
G |
14: 74,943,293 (GRCm39) |
S291* |
probably null |
Het |
| Itga5 |
G |
A |
15: 103,265,209 (GRCm39) |
Q233* |
probably null |
Het |
| Jazf1 |
C |
A |
6: 52,789,168 (GRCm39) |
R102L |
probably damaging |
Het |
| Kif6 |
T |
G |
17: 50,021,141 (GRCm39) |
L322R |
probably damaging |
Het |
| Ktn1 |
A |
C |
14: 47,904,873 (GRCm39) |
K217T |
probably damaging |
Het |
| Lig4 |
A |
T |
8: 10,023,012 (GRCm39) |
V256E |
possibly damaging |
Het |
| Lrp1 |
G |
T |
10: 127,403,233 (GRCm39) |
D2113E |
probably damaging |
Het |
| Lrp1 |
A |
T |
10: 127,411,155 (GRCm39) |
D1399E |
probably benign |
Het |
| Mmel1 |
A |
G |
4: 154,979,443 (GRCm39) |
E717G |
probably damaging |
Het |
| Mndal |
G |
T |
1: 173,699,032 (GRCm39) |
P155H |
possibly damaging |
Het |
| Mycbpap |
A |
G |
11: 94,402,449 (GRCm39) |
|
probably null |
Het |
| Nedd1 |
T |
C |
10: 92,555,476 (GRCm39) |
E3G |
probably damaging |
Het |
| Nlgn1 |
A |
T |
3: 25,490,073 (GRCm39) |
N551K |
probably damaging |
Het |
| Or2ag15 |
A |
G |
7: 106,340,212 (GRCm39) |
C310R |
probably benign |
Het |
| Or2g25 |
A |
T |
17: 37,970,661 (GRCm39) |
C188S |
probably damaging |
Het |
| Or4k52 |
A |
T |
2: 111,610,693 (GRCm39) |
|
probably null |
Het |
| Or5ac17 |
T |
G |
16: 59,036,347 (GRCm39) |
T210P |
probably damaging |
Het |
| Or5p56 |
A |
G |
7: 107,589,740 (GRCm39) |
H56R |
probably benign |
Het |
| Pank3 |
G |
A |
11: 35,672,508 (GRCm39) |
V304M |
probably benign |
Het |
| Phf3 |
G |
A |
1: 30,844,729 (GRCm39) |
T1410I |
probably benign |
Het |
| Ppm1k |
A |
G |
6: 57,502,142 (GRCm39) |
I7T |
possibly damaging |
Het |
| Ppp1r12c |
T |
C |
7: 4,500,424 (GRCm39) |
D73G |
probably damaging |
Het |
| Prelid2 |
T |
G |
18: 42,014,332 (GRCm39) |
M165L |
probably benign |
Het |
| Prkd3 |
A |
C |
17: 79,260,125 (GRCm39) |
L826R |
probably damaging |
Het |
| Ptchd4 |
A |
T |
17: 42,814,433 (GRCm39) |
N778I |
probably damaging |
Het |
| Ptprm |
T |
C |
17: 67,000,866 (GRCm39) |
D1063G |
possibly damaging |
Het |
| Rab27a |
C |
A |
9: 72,982,764 (GRCm39) |
T23N |
probably damaging |
Het |
| Rasgrf2 |
A |
T |
13: 92,044,205 (GRCm39) |
F949L |
probably benign |
Het |
| Rbm33 |
A |
G |
5: 28,542,002 (GRCm39) |
N68D |
probably damaging |
Het |
| Rgl1 |
A |
T |
1: 152,462,284 (GRCm39) |
L109Q |
probably damaging |
Het |
| Rnf20 |
A |
G |
4: 49,638,197 (GRCm39) |
N103S |
possibly damaging |
Het |
| Sbno1 |
G |
A |
5: 124,530,675 (GRCm39) |
L875F |
probably damaging |
Het |
| Scube1 |
T |
A |
15: 83,512,277 (GRCm39) |
|
probably null |
Het |
| Selenbp1 |
G |
A |
3: 94,844,669 (GRCm39) |
V109M |
probably damaging |
Het |
| Serpina3c |
T |
A |
12: 104,117,805 (GRCm39) |
I178F |
probably damaging |
Het |
| Shisa8 |
C |
T |
15: 82,092,702 (GRCm39) |
G63D |
probably damaging |
Het |
| Snx14 |
T |
C |
9: 88,284,277 (GRCm39) |
R464G |
possibly damaging |
Het |
| Snx25 |
A |
T |
8: 46,577,119 (GRCm39) |
M1K |
probably null |
Het |
| Sorcs3 |
C |
A |
19: 48,694,448 (GRCm39) |
T574K |
possibly damaging |
Het |
| Syne2 |
A |
G |
12: 76,150,557 (GRCm39) |
E6528G |
probably damaging |
Het |
| Syt5 |
T |
C |
7: 4,543,245 (GRCm39) |
E338G |
probably damaging |
Het |
| Tbk1 |
T |
C |
10: 121,387,223 (GRCm39) |
K691E |
probably benign |
Het |
| Tenm3 |
G |
A |
8: 48,848,611 (GRCm39) |
T11I |
probably damaging |
Het |
| Thrb |
A |
G |
14: 18,002,597 (GRCm38) |
H87R |
probably damaging |
Het |
| Tlr4 |
T |
A |
4: 66,757,933 (GRCm39) |
M242K |
possibly damaging |
Het |
| Tm4sf19 |
T |
C |
16: 32,224,820 (GRCm39) |
M56T |
possibly damaging |
Het |
| Tmem212 |
T |
A |
3: 27,940,620 (GRCm39) |
R66* |
probably null |
Het |
| Tmem39b |
G |
T |
4: 129,578,275 (GRCm39) |
D315E |
probably benign |
Het |
| Tnxb |
T |
C |
17: 34,937,612 (GRCm39) |
F3834L |
probably damaging |
Het |
| Trim36 |
A |
T |
18: 46,319,250 (GRCm39) |
L225* |
probably null |
Het |
| Trim42 |
A |
T |
9: 97,247,732 (GRCm39) |
H321Q |
probably damaging |
Het |
| Trio |
G |
T |
15: 27,732,726 (GRCm39) |
Q3052K |
probably benign |
Het |
| Trpm3 |
T |
C |
19: 22,955,698 (GRCm39) |
I1091T |
probably benign |
Het |
| Tst |
T |
C |
15: 78,284,143 (GRCm39) |
E228G |
possibly damaging |
Het |
| Ttn |
T |
C |
2: 76,702,060 (GRCm39) |
|
probably benign |
Het |
| Uap1 |
A |
C |
1: 169,978,510 (GRCm39) |
|
probably null |
Het |
| Ush2a |
T |
C |
1: 188,530,011 (GRCm39) |
S3267P |
possibly damaging |
Het |
| Usp5 |
T |
C |
6: 124,802,129 (GRCm39) |
T38A |
probably benign |
Het |
| Uvssa |
A |
T |
5: 33,545,152 (GRCm39) |
Q84L |
probably damaging |
Het |
| Vmn1r159 |
T |
G |
7: 22,542,693 (GRCm39) |
H113P |
probably damaging |
Het |
| Vps13d |
A |
T |
4: 144,824,742 (GRCm39) |
|
probably null |
Het |
| Zfp182 |
T |
A |
X: 20,897,799 (GRCm39) |
I166L |
probably benign |
Het |
| Zfp811 |
A |
T |
17: 33,016,622 (GRCm39) |
Y472N |
probably damaging |
Het |
|
| Other mutations in Nup210 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01139:Nup210
|
APN |
6 |
91,007,079 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL01532:Nup210
|
APN |
6 |
91,062,981 (GRCm39) |
splice site |
probably benign |
|
|
IGL01574:Nup210
|
APN |
6 |
91,017,546 (GRCm39) |
missense |
probably benign |
0.35 |
|
IGL01621:Nup210
|
APN |
6 |
91,007,099 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01976:Nup210
|
APN |
6 |
91,030,596 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
IGL02089:Nup210
|
APN |
6 |
91,053,680 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL02291:Nup210
|
APN |
6 |
91,078,250 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03013:Nup210
|
APN |
6 |
91,030,361 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03046:Nup210
|
APN |
6 |
90,995,978 (GRCm39) |
splice site |
probably benign |
|
|
IGL03136:Nup210
|
APN |
6 |
91,005,843 (GRCm39) |
missense |
probably benign |
0.32 |
|
IGL03139:Nup210
|
APN |
6 |
90,997,221 (GRCm39) |
missense |
probably benign |
0.08 |
|
IGL03195:Nup210
|
APN |
6 |
90,992,832 (GRCm39) |
missense |
probably benign |
0.32 |
|
IGL03344:Nup210
|
APN |
6 |
90,998,411 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
brotherhood
|
UTSW |
6 |
91,013,451 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
equality
|
UTSW |
6 |
90,998,377 (GRCm39) |
critical splice donor site |
probably null |
|
|
fraternity
|
UTSW |
6 |
91,019,235 (GRCm39) |
critical splice donor site |
probably null |
|
|
Liberty
|
UTSW |
6 |
90,997,162 (GRCm39) |
missense |
probably benign |
0.04 |
|
napoleonic
|
UTSW |
6 |
91,030,434 (GRCm39) |
missense |
probably damaging |
1.00 |
|
unity
|
UTSW |
6 |
91,008,650 (GRCm39) |
nonsense |
probably null |
|
|
IGL03134:Nup210
|
UTSW |
6 |
91,007,172 (GRCm39) |
missense |
probably damaging |
0.99 |
|
PIT4810001:Nup210
|
UTSW |
6 |
91,007,106 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0100:Nup210
|
UTSW |
6 |
91,046,175 (GRCm39) |
missense |
probably benign |
0.04 |
|
R0348:Nup210
|
UTSW |
6 |
91,051,292 (GRCm39) |
missense |
probably benign |
0.27 |
|
R0385:Nup210
|
UTSW |
6 |
91,005,777 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R0551:Nup210
|
UTSW |
6 |
90,998,466 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R0606:Nup210
|
UTSW |
6 |
91,003,911 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1053:Nup210
|
UTSW |
6 |
91,005,793 (GRCm39) |
missense |
probably benign |
0.41 |
|
R1301:Nup210
|
UTSW |
6 |
91,019,329 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R1381:Nup210
|
UTSW |
6 |
91,052,942 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1464:Nup210
|
UTSW |
6 |
91,030,551 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R1464:Nup210
|
UTSW |
6 |
91,030,551 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R1487:Nup210
|
UTSW |
6 |
91,019,558 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1529:Nup210
|
UTSW |
6 |
91,013,358 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1531:Nup210
|
UTSW |
6 |
91,011,823 (GRCm39) |
missense |
probably benign |
0.05 |
|
R1668:Nup210
|
UTSW |
6 |
91,005,787 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1694:Nup210
|
UTSW |
6 |
91,039,785 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1803:Nup210
|
UTSW |
6 |
91,051,264 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1851:Nup210
|
UTSW |
6 |
90,993,036 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2145:Nup210
|
UTSW |
6 |
91,005,858 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R2196:Nup210
|
UTSW |
6 |
91,032,226 (GRCm39) |
missense |
probably benign |
0.02 |
|
R2308:Nup210
|
UTSW |
6 |
91,017,850 (GRCm39) |
missense |
probably benign |
0.19 |
|
R2419:Nup210
|
UTSW |
6 |
90,994,538 (GRCm39) |
splice site |
probably benign |
|
|
R2912:Nup210
|
UTSW |
6 |
91,003,956 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3413:Nup210
|
UTSW |
6 |
91,002,224 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3718:Nup210
|
UTSW |
6 |
90,997,162 (GRCm39) |
missense |
probably benign |
0.04 |
|
R3753:Nup210
|
UTSW |
6 |
90,998,377 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4058:Nup210
|
UTSW |
6 |
91,037,602 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4840:Nup210
|
UTSW |
6 |
91,008,650 (GRCm39) |
nonsense |
probably null |
|
|
R4912:Nup210
|
UTSW |
6 |
90,994,511 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4967:Nup210
|
UTSW |
6 |
91,013,451 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R4996:Nup210
|
UTSW |
6 |
91,030,418 (GRCm39) |
missense |
probably benign |
0.16 |
|
R5074:Nup210
|
UTSW |
6 |
91,032,309 (GRCm39) |
missense |
probably benign |
0.16 |
|
R5233:Nup210
|
UTSW |
6 |
91,003,951 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5352:Nup210
|
UTSW |
6 |
91,046,298 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5490:Nup210
|
UTSW |
6 |
91,062,970 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5511:Nup210
|
UTSW |
6 |
91,003,945 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5773:Nup210
|
UTSW |
6 |
91,062,865 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6064:Nup210
|
UTSW |
6 |
91,032,273 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6209:Nup210
|
UTSW |
6 |
91,002,337 (GRCm39) |
missense |
probably benign |
|
|
R6299:Nup210
|
UTSW |
6 |
91,051,270 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R6705:Nup210
|
UTSW |
6 |
91,064,942 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R6855:Nup210
|
UTSW |
6 |
91,017,835 (GRCm39) |
missense |
probably benign |
0.13 |
|
R6856:Nup210
|
UTSW |
6 |
91,064,895 (GRCm39) |
nonsense |
probably null |
|
|
R6911:Nup210
|
UTSW |
6 |
91,007,112 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6955:Nup210
|
UTSW |
6 |
91,064,909 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7045:Nup210
|
UTSW |
6 |
91,031,433 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7081:Nup210
|
UTSW |
6 |
91,037,647 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R7163:Nup210
|
UTSW |
6 |
91,050,313 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7305:Nup210
|
UTSW |
6 |
91,064,948 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7387:Nup210
|
UTSW |
6 |
90,998,378 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7404:Nup210
|
UTSW |
6 |
91,050,227 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7469:Nup210
|
UTSW |
6 |
90,995,874 (GRCm39) |
missense |
probably benign |
0.08 |
|
R7603:Nup210
|
UTSW |
6 |
91,053,679 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7731:Nup210
|
UTSW |
6 |
91,048,870 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R7822:Nup210
|
UTSW |
6 |
90,995,759 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R7944:Nup210
|
UTSW |
6 |
91,050,179 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8032:Nup210
|
UTSW |
6 |
91,051,331 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8039:Nup210
|
UTSW |
6 |
91,047,215 (GRCm39) |
missense |
probably benign |
0.09 |
|
R8081:Nup210
|
UTSW |
6 |
91,053,657 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8177:Nup210
|
UTSW |
6 |
90,991,470 (GRCm39) |
missense |
probably benign |
|
|
R8331:Nup210
|
UTSW |
6 |
91,030,648 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R8356:Nup210
|
UTSW |
6 |
91,051,330 (GRCm39) |
missense |
probably benign |
0.32 |
|
R8530:Nup210
|
UTSW |
6 |
91,053,627 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R8896:Nup210
|
UTSW |
6 |
91,019,235 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8926:Nup210
|
UTSW |
6 |
91,030,434 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9093:Nup210
|
UTSW |
6 |
91,066,872 (GRCm39) |
missense |
probably benign |
0.16 |
|
R9130:Nup210
|
UTSW |
6 |
91,020,799 (GRCm39) |
missense |
probably benign |
0.08 |
|
R9136:Nup210
|
UTSW |
6 |
91,020,830 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R9260:Nup210
|
UTSW |
6 |
91,039,785 (GRCm39) |
missense |
probably benign |
0.09 |
|
R9292:Nup210
|
UTSW |
6 |
91,051,235 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R9444:Nup210
|
UTSW |
6 |
91,048,885 (GRCm39) |
missense |
probably benign |
|
|
R9482:Nup210
|
UTSW |
6 |
91,019,608 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9506:Nup210
|
UTSW |
6 |
91,048,856 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R9621:Nup210
|
UTSW |
6 |
90,994,375 (GRCm39) |
missense |
probably benign |
0.18 |
|
R9735:Nup210
|
UTSW |
6 |
91,030,630 (GRCm39) |
missense |
probably benign |
0.42 |
|
X0067:Nup210
|
UTSW |
6 |
91,051,262 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Nup210
|
UTSW |
6 |
91,064,889 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
Z1177:Nup210
|
UTSW |
6 |
90,997,167 (GRCm39) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- ACTCCACTCAGGCATGGAAGAGAC -3'
(R):5'- CTAGGTGTATGTGATTGAGCCCAGC -3'
Sequencing Primer
(F):5'- GCATGGAAGAGACACTTTGC -3'
(R):5'- AGCAGCATGGAGTTTGCC -3'
|
| Posted On |
2014-04-13 |
Incidental Mutation