Incidental Mutation 'R1513:Abca15'
| ID |
168530 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Abca15
|
| Ensembl Gene |
ENSMUSG00000054746 |
| Gene Name |
ATP-binding cassette, sub-family A member 15 |
| Synonyms |
4930500I12Rik |
| MMRRC Submission |
039560-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.059)
|
| Stock # |
R1513 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
7 |
| Chromosomal Location |
119927893-120006910 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 119939322 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Phenylalanine
at position 239
(I239F)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000112821
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000076272]
[ENSMUST00000121265]
|
| AlphaFold |
E9PWH4 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000076272
AA Change: I239F
PolyPhen 2
Score 0.935 (Sensitivity: 0.80; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000075621
Gene: ENSMUSG00000054746
AA Change: I239F
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:ABC2_membrane_3
|
24 |
464 |
5.7e-21 |
PFAM |
|
AAA
|
550 |
732 |
9.14e-11 |
SMART |
|
Pfam:ABC2_membrane_3
|
892 |
1293 |
7.9e-24 |
PFAM |
|
AAA
|
1381 |
1565 |
1.16e-3 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000121265
AA Change: I239F
PolyPhen 2
Score 0.964 (Sensitivity: 0.78; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000112821
Gene: ENSMUSG00000054746
AA Change: I239F
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:ABC2_membrane_3
|
24 |
464 |
2.1e-21 |
PFAM |
|
AAA
|
550 |
732 |
9.14e-11 |
SMART |
|
Pfam:ABC2_membrane_3
|
907 |
1293 |
1e-25 |
PFAM |
|
AAA
|
1381 |
1565 |
1.16e-3 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000140459
|
| Coding Region Coverage |
- 1x: 98.9%
- 3x: 97.9%
- 10x: 94.7%
- 20x: 87.2%
|
| Validation Efficiency |
|
| Allele List at MGI |
All alleles(2) : Targeted(2)
|
| Other mutations in this stock |
Total: 107 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1500011B03Rik |
A |
T |
5: 114,947,334 (GRCm39) |
C64* |
probably null |
Het |
| 1700003H04Rik |
A |
C |
3: 124,368,985 (GRCm39) |
Y109D |
possibly damaging |
Het |
| Adgrv1 |
A |
G |
13: 81,741,167 (GRCm39) |
V99A |
probably damaging |
Het |
| Adgrv1 |
A |
T |
13: 81,705,076 (GRCm39) |
I1578K |
probably damaging |
Het |
| Ap4e1 |
G |
T |
2: 126,903,475 (GRCm39) |
K792N |
probably null |
Het |
| Ap5b1 |
G |
A |
19: 5,619,892 (GRCm39) |
W437* |
probably null |
Het |
| Arhgef17 |
A |
G |
7: 100,580,069 (GRCm39) |
L293P |
probably benign |
Het |
| Arhgef33 |
A |
C |
17: 80,678,818 (GRCm39) |
M505L |
probably benign |
Het |
| Arih1 |
T |
A |
9: 59,310,663 (GRCm39) |
R320S |
probably damaging |
Het |
| Atp1b3 |
A |
T |
9: 96,246,206 (GRCm39) |
M1K |
probably null |
Het |
| Bbs2 |
T |
C |
8: 94,816,472 (GRCm39) |
D130G |
possibly damaging |
Het |
| Bscl2 |
G |
A |
19: 8,818,509 (GRCm39) |
R38H |
probably damaging |
Het |
| Cad |
A |
G |
5: 31,226,106 (GRCm39) |
Y1102C |
probably damaging |
Het |
| Cc2d1b |
G |
A |
4: 108,490,423 (GRCm39) |
R825Q |
probably damaging |
Het |
| Ccdc39 |
A |
G |
3: 33,893,294 (GRCm39) |
V97A |
possibly damaging |
Het |
| Ccr1 |
T |
C |
9: 123,764,510 (GRCm39) |
T7A |
probably benign |
Het |
| Cd33 |
A |
G |
7: 43,181,618 (GRCm39) |
S181P |
probably damaging |
Het |
| Cdc20 |
A |
C |
4: 118,290,304 (GRCm39) |
S452R |
probably damaging |
Het |
| Cdk8 |
A |
T |
5: 146,233,188 (GRCm39) |
I229F |
possibly damaging |
Het |
| Ces3a |
A |
T |
8: 105,776,909 (GRCm39) |
N131Y |
probably damaging |
Het |
| Cgnl1 |
A |
G |
9: 71,631,872 (GRCm39) |
I493T |
probably benign |
Het |
| Chia1 |
G |
A |
3: 106,039,220 (GRCm39) |
V437M |
probably benign |
Het |
| Chrna2 |
G |
A |
14: 66,380,878 (GRCm39) |
R49H |
probably benign |
Het |
| Clec12b |
A |
G |
6: 129,353,265 (GRCm39) |
C241R |
probably damaging |
Het |
| Col11a1 |
A |
G |
3: 113,890,803 (GRCm39) |
D380G |
unknown |
Het |
| Crebbp |
A |
G |
16: 3,933,749 (GRCm39) |
S948P |
probably damaging |
Het |
| Dchs1 |
G |
A |
7: 105,421,278 (GRCm39) |
R381* |
probably null |
Het |
| Defb19 |
A |
T |
2: 152,418,085 (GRCm39) |
*84R |
probably null |
Het |
| Dnah8 |
T |
C |
17: 30,892,862 (GRCm39) |
F816L |
probably benign |
Het |
| Dync2h1 |
T |
A |
9: 7,103,663 (GRCm39) |
I371F |
possibly damaging |
Het |
| Ezhip |
GTCATCATCATCATC |
GTCATCATCATCATCATC |
X: 5,994,645 (GRCm39) |
|
probably benign |
Het |
| Fggy |
T |
C |
4: 95,790,295 (GRCm39) |
|
probably benign |
Het |
| Galnt12 |
G |
A |
4: 47,117,956 (GRCm39) |
C125Y |
probably damaging |
Het |
| Gm4952 |
A |
T |
19: 12,602,039 (GRCm39) |
D149V |
probably damaging |
Het |
| Gm6309 |
A |
T |
5: 146,107,393 (GRCm39) |
H37Q |
possibly damaging |
Het |
| Gmnn |
A |
G |
13: 24,940,615 (GRCm39) |
L78P |
possibly damaging |
Het |
| Golga4 |
C |
A |
9: 118,384,800 (GRCm39) |
Q613K |
probably benign |
Het |
| Iqgap2 |
A |
T |
13: 95,766,518 (GRCm39) |
I1495K |
probably damaging |
Het |
| Junb |
T |
C |
8: 85,704,758 (GRCm39) |
T101A |
probably damaging |
Het |
| Kif21b |
T |
C |
1: 136,083,849 (GRCm39) |
Y699H |
probably damaging |
Het |
| Klf17 |
T |
C |
4: 117,618,132 (GRCm39) |
E75G |
probably damaging |
Het |
| Klra17 |
T |
C |
6: 129,849,277 (GRCm39) |
E99G |
possibly damaging |
Het |
| Knop1 |
CTCTTCTTCTTCTTCTTCTTCTTC |
CTCTTCTTCTTCTTCTTCTTC |
7: 118,451,672 (GRCm39) |
|
probably benign |
Het |
| Krt87 |
C |
T |
15: 101,387,538 (GRCm39) |
V167M |
probably benign |
Het |
| Lce1m |
A |
G |
3: 92,925,932 (GRCm39) |
|
probably benign |
Het |
| Lpin3 |
A |
T |
2: 160,746,468 (GRCm39) |
Y709F |
probably damaging |
Het |
| Ltbp2 |
T |
A |
12: 84,838,718 (GRCm39) |
D1080V |
probably damaging |
Het |
| Mycbp2 |
G |
A |
14: 103,441,825 (GRCm39) |
T1980I |
probably damaging |
Het |
| Myo1g |
T |
A |
11: 6,465,140 (GRCm39) |
K435M |
probably damaging |
Het |
| Mypn |
T |
A |
10: 63,005,147 (GRCm39) |
N320I |
probably damaging |
Het |
| Naip5 |
A |
T |
13: 100,358,714 (GRCm39) |
W841R |
probably benign |
Het |
| Ncapd2 |
A |
T |
6: 125,147,955 (GRCm39) |
M1124K |
probably damaging |
Het |
| Ncf4 |
A |
G |
15: 78,146,560 (GRCm39) |
D330G |
probably benign |
Het |
| Ndst3 |
C |
T |
3: 123,395,104 (GRCm39) |
V509M |
possibly damaging |
Het |
| Neb |
A |
T |
2: 52,117,256 (GRCm39) |
D4105E |
probably damaging |
Het |
| Nfix |
G |
A |
8: 85,453,155 (GRCm39) |
R300C |
probably damaging |
Het |
| Nsrp1 |
A |
T |
11: 76,937,445 (GRCm39) |
F250L |
probably benign |
Het |
| Or11g7 |
A |
G |
14: 50,691,138 (GRCm39) |
I210V |
probably benign |
Het |
| Or4l15 |
T |
C |
14: 50,198,558 (GRCm39) |
|
probably null |
Het |
| Or52d1 |
C |
T |
7: 103,755,671 (GRCm39) |
L62F |
probably benign |
Het |
| Or52k2 |
G |
T |
7: 102,254,509 (GRCm39) |
G316V |
probably benign |
Het |
| Or5m12 |
A |
T |
2: 85,735,015 (GRCm39) |
Y128N |
probably damaging |
Het |
| Or8k3b |
C |
T |
2: 86,521,141 (GRCm39) |
M59I |
possibly damaging |
Het |
| Oxr1 |
A |
G |
15: 41,660,870 (GRCm39) |
D67G |
probably damaging |
Het |
| P2ry12 |
A |
T |
3: 59,125,498 (GRCm39) |
I59N |
probably damaging |
Het |
| Pcdhb12 |
G |
T |
18: 37,570,111 (GRCm39) |
G419V |
probably damaging |
Het |
| Pdzd2 |
G |
T |
15: 12,373,915 (GRCm39) |
S2073R |
possibly damaging |
Het |
| Pex5l |
C |
A |
3: 33,069,162 (GRCm39) |
E112* |
probably null |
Het |
| Plaur |
A |
G |
7: 24,172,016 (GRCm39) |
D163G |
probably benign |
Het |
| Plk2 |
A |
G |
13: 110,536,622 (GRCm39) |
Y638C |
probably benign |
Het |
| Ppp1r15b |
A |
G |
1: 133,061,088 (GRCm39) |
N535S |
probably benign |
Het |
| Ppp2r1b |
T |
C |
9: 50,781,445 (GRCm39) |
L21P |
probably damaging |
Het |
| Prkar2a |
G |
A |
9: 108,605,469 (GRCm39) |
V176I |
possibly damaging |
Het |
| Ptpro |
T |
A |
6: 137,420,592 (GRCm39) |
V1007D |
probably damaging |
Het |
| Rag1 |
A |
G |
2: 101,473,336 (GRCm39) |
M602T |
possibly damaging |
Het |
| Rb1 |
A |
G |
14: 73,559,524 (GRCm39) |
V60A |
probably benign |
Het |
| Rgs20 |
T |
A |
1: 4,982,560 (GRCm39) |
I303F |
probably damaging |
Het |
| Rnf43 |
T |
A |
11: 87,620,257 (GRCm39) |
I240N |
probably damaging |
Het |
| Romo1 |
G |
A |
2: 155,986,433 (GRCm39) |
V19M |
probably benign |
Het |
| Ryr1 |
A |
G |
7: 28,770,046 (GRCm39) |
S2676P |
probably damaging |
Het |
| Ryr3 |
G |
A |
2: 112,539,542 (GRCm39) |
Q3233* |
probably null |
Het |
| Skic2 |
G |
T |
17: 35,066,420 (GRCm39) |
P188T |
probably damaging |
Het |
| Slc26a6 |
A |
G |
9: 108,733,035 (GRCm39) |
R5G |
probably benign |
Het |
| Slc33a1 |
A |
G |
3: 63,871,376 (GRCm39) |
L79P |
probably damaging |
Het |
| Snx31 |
G |
A |
15: 36,545,745 (GRCm39) |
R91C |
probably damaging |
Het |
| Tecpr2 |
T |
C |
12: 110,921,234 (GRCm39) |
I1269T |
possibly damaging |
Het |
| Tjap1 |
G |
T |
17: 46,572,368 (GRCm39) |
D89E |
probably benign |
Het |
| Tmem53 |
A |
T |
4: 117,123,090 (GRCm39) |
Q39L |
probably damaging |
Het |
| Tmod1 |
G |
T |
4: 46,083,549 (GRCm39) |
V95F |
possibly damaging |
Het |
| Trim30c |
A |
C |
7: 104,031,896 (GRCm39) |
H306Q |
probably benign |
Het |
| Trpm3 |
A |
T |
19: 22,964,236 (GRCm39) |
M1244L |
possibly damaging |
Het |
| Tspan32 |
A |
G |
7: 142,558,886 (GRCm39) |
I14V |
probably null |
Het |
| Ube4b |
A |
G |
4: 149,436,035 (GRCm39) |
V695A |
probably benign |
Het |
| Ubxn11 |
G |
A |
4: 133,851,452 (GRCm39) |
|
probably null |
Het |
| Ugt3a1 |
A |
G |
15: 9,361,610 (GRCm39) |
I129V |
probably benign |
Het |
| Vmn1r45 |
A |
G |
6: 89,910,058 (GRCm39) |
V304A |
probably damaging |
Het |
| Vmn2r124 |
A |
T |
17: 18,283,535 (GRCm39) |
S410C |
probably damaging |
Het |
| Vmn2r15 |
T |
A |
5: 109,441,195 (GRCm39) |
D221V |
probably damaging |
Het |
| Vmn2r79 |
G |
A |
7: 86,686,652 (GRCm39) |
V678I |
probably benign |
Het |
| Vps13b |
A |
T |
15: 35,438,876 (GRCm39) |
R319* |
probably null |
Het |
| Wdr95 |
G |
A |
5: 149,522,759 (GRCm39) |
R639Q |
probably benign |
Het |
| Xirp2 |
A |
G |
2: 67,341,874 (GRCm39) |
I1372V |
probably benign |
Het |
| Xpo5 |
T |
A |
17: 46,537,906 (GRCm39) |
M611K |
probably benign |
Het |
| Zfat |
A |
G |
15: 68,084,529 (GRCm39) |
C121R |
probably damaging |
Het |
| Zfp382 |
A |
T |
7: 29,832,721 (GRCm39) |
Y124F |
probably benign |
Het |
| Zfp512b |
A |
G |
2: 181,230,982 (GRCm39) |
F371S |
probably benign |
Het |
| Zfy2 |
A |
G |
Y: 2,116,185 (GRCm39) |
V285A |
probably benign |
Het |
|
| Other mutations in Abca15 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00429:Abca15
|
APN |
7 |
119,996,277 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00505:Abca15
|
APN |
7 |
119,968,459 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL00851:Abca15
|
APN |
7 |
119,939,230 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00985:Abca15
|
APN |
7 |
119,996,241 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01114:Abca15
|
APN |
7 |
119,960,643 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01287:Abca15
|
APN |
7 |
119,932,081 (GRCm39) |
utr 3 prime |
probably benign |
|
|
IGL01333:Abca15
|
APN |
7 |
119,981,531 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01482:Abca15
|
APN |
7 |
119,981,969 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01610:Abca15
|
APN |
7 |
119,939,867 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02238:Abca15
|
APN |
7 |
119,995,829 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL02377:Abca15
|
APN |
7 |
119,965,133 (GRCm39) |
splice site |
probably benign |
|
|
IGL02666:Abca15
|
APN |
7 |
119,934,431 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02836:Abca15
|
APN |
7 |
119,987,439 (GRCm39) |
missense |
probably benign |
|
|
IGL03337:Abca15
|
APN |
7 |
119,995,930 (GRCm39) |
missense |
probably benign |
0.24 |
|
IGL03354:Abca15
|
APN |
7 |
119,993,711 (GRCm39) |
nonsense |
probably null |
|
|
H8562:Abca15
|
UTSW |
7 |
119,974,077 (GRCm39) |
splice site |
probably benign |
|
|
IGL03098:Abca15
|
UTSW |
7 |
119,987,499 (GRCm39) |
splice site |
probably null |
|
|
R0029:Abca15
|
UTSW |
7 |
119,945,225 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0029:Abca15
|
UTSW |
7 |
119,945,225 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0076:Abca15
|
UTSW |
7 |
119,972,908 (GRCm39) |
splice site |
probably benign |
|
|
R0165:Abca15
|
UTSW |
7 |
119,950,126 (GRCm39) |
splice site |
probably benign |
|
|
R0311:Abca15
|
UTSW |
7 |
120,002,127 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0387:Abca15
|
UTSW |
7 |
119,932,075 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0610:Abca15
|
UTSW |
7 |
119,965,009 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R0612:Abca15
|
UTSW |
7 |
119,936,478 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0704:Abca15
|
UTSW |
7 |
119,953,746 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0890:Abca15
|
UTSW |
7 |
119,972,936 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0961:Abca15
|
UTSW |
7 |
119,960,208 (GRCm39) |
nonsense |
probably null |
|
|
R1144:Abca15
|
UTSW |
7 |
119,960,083 (GRCm39) |
splice site |
probably benign |
|
|
R1412:Abca15
|
UTSW |
7 |
119,944,546 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R1419:Abca15
|
UTSW |
7 |
119,974,125 (GRCm39) |
missense |
probably benign |
0.10 |
|
R1467:Abca15
|
UTSW |
7 |
119,939,761 (GRCm39) |
splice site |
probably null |
|
|
R1467:Abca15
|
UTSW |
7 |
119,939,761 (GRCm39) |
splice site |
probably null |
|
|
R1469:Abca15
|
UTSW |
7 |
119,981,720 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1469:Abca15
|
UTSW |
7 |
119,981,720 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1493:Abca15
|
UTSW |
7 |
119,981,513 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1702:Abca15
|
UTSW |
7 |
119,981,925 (GRCm39) |
missense |
probably benign |
0.10 |
|
R1857:Abca15
|
UTSW |
7 |
119,960,592 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1893:Abca15
|
UTSW |
7 |
119,939,776 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R1901:Abca15
|
UTSW |
7 |
119,945,322 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1951:Abca15
|
UTSW |
7 |
119,960,655 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1953:Abca15
|
UTSW |
7 |
119,960,655 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1962:Abca15
|
UTSW |
7 |
119,940,468 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2063:Abca15
|
UTSW |
7 |
119,960,127 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R2141:Abca15
|
UTSW |
7 |
120,006,697 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2145:Abca15
|
UTSW |
7 |
119,953,701 (GRCm39) |
missense |
probably benign |
0.08 |
|
R2182:Abca15
|
UTSW |
7 |
119,939,450 (GRCm39) |
nonsense |
probably null |
|
|
R2425:Abca15
|
UTSW |
7 |
119,959,033 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2444:Abca15
|
UTSW |
7 |
119,965,120 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3023:Abca15
|
UTSW |
7 |
119,982,002 (GRCm39) |
missense |
probably benign |
0.40 |
|
R3079:Abca15
|
UTSW |
7 |
119,984,392 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3106:Abca15
|
UTSW |
7 |
119,995,856 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R3622:Abca15
|
UTSW |
7 |
119,950,036 (GRCm39) |
nonsense |
probably null |
|
|
R4085:Abca15
|
UTSW |
7 |
119,981,949 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4233:Abca15
|
UTSW |
7 |
120,002,202 (GRCm39) |
nonsense |
probably null |
|
|
R4591:Abca15
|
UTSW |
7 |
119,981,636 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4612:Abca15
|
UTSW |
7 |
119,934,384 (GRCm39) |
missense |
probably benign |
0.03 |
|
R4721:Abca15
|
UTSW |
7 |
119,949,998 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4838:Abca15
|
UTSW |
7 |
119,944,523 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4940:Abca15
|
UTSW |
7 |
119,931,917 (GRCm39) |
missense |
probably benign |
|
|
R4963:Abca15
|
UTSW |
7 |
119,960,142 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4993:Abca15
|
UTSW |
7 |
120,000,941 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5022:Abca15
|
UTSW |
7 |
119,945,319 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5030:Abca15
|
UTSW |
7 |
119,939,224 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5072:Abca15
|
UTSW |
7 |
120,006,198 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5090:Abca15
|
UTSW |
7 |
119,984,422 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5309:Abca15
|
UTSW |
7 |
119,944,592 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5310:Abca15
|
UTSW |
7 |
119,931,839 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R5312:Abca15
|
UTSW |
7 |
119,944,592 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5482:Abca15
|
UTSW |
7 |
119,968,370 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5596:Abca15
|
UTSW |
7 |
120,000,972 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R5853:Abca15
|
UTSW |
7 |
119,939,806 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5950:Abca15
|
UTSW |
7 |
119,981,879 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5953:Abca15
|
UTSW |
7 |
119,960,241 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6072:Abca15
|
UTSW |
7 |
119,987,481 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6131:Abca15
|
UTSW |
7 |
119,939,428 (GRCm39) |
missense |
probably benign |
0.03 |
|
R6132:Abca15
|
UTSW |
7 |
119,960,643 (GRCm39) |
missense |
probably benign |
0.14 |
|
R6136:Abca15
|
UTSW |
7 |
119,939,272 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R6207:Abca15
|
UTSW |
7 |
119,973,017 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6315:Abca15
|
UTSW |
7 |
119,945,315 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6417:Abca15
|
UTSW |
7 |
119,996,351 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6420:Abca15
|
UTSW |
7 |
119,996,351 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6595:Abca15
|
UTSW |
7 |
119,993,710 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6653:Abca15
|
UTSW |
7 |
119,945,229 (GRCm39) |
missense |
probably benign |
0.03 |
|
R6859:Abca15
|
UTSW |
7 |
120,002,217 (GRCm39) |
nonsense |
probably null |
|
|
R6983:Abca15
|
UTSW |
7 |
119,953,686 (GRCm39) |
missense |
probably benign |
0.26 |
|
R7127:Abca15
|
UTSW |
7 |
119,931,825 (GRCm39) |
missense |
probably benign |
0.06 |
|
R7205:Abca15
|
UTSW |
7 |
119,993,587 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R7336:Abca15
|
UTSW |
7 |
119,987,456 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R7426:Abca15
|
UTSW |
7 |
119,945,221 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R7745:Abca15
|
UTSW |
7 |
119,931,440 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7751:Abca15
|
UTSW |
7 |
119,965,044 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R7806:Abca15
|
UTSW |
7 |
119,932,059 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8042:Abca15
|
UTSW |
7 |
120,002,233 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R8098:Abca15
|
UTSW |
7 |
119,960,619 (GRCm39) |
missense |
probably benign |
0.09 |
|
R8153:Abca15
|
UTSW |
7 |
119,999,812 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8247:Abca15
|
UTSW |
7 |
119,936,445 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R8259:Abca15
|
UTSW |
7 |
119,939,422 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8272:Abca15
|
UTSW |
7 |
120,006,665 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8295:Abca15
|
UTSW |
7 |
119,974,188 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8757:Abca15
|
UTSW |
7 |
120,006,631 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8759:Abca15
|
UTSW |
7 |
120,006,631 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8905:Abca15
|
UTSW |
7 |
119,960,771 (GRCm39) |
missense |
probably benign |
0.28 |
|
R9145:Abca15
|
UTSW |
7 |
119,987,388 (GRCm39) |
missense |
probably benign |
0.13 |
|
R9217:Abca15
|
UTSW |
7 |
119,987,439 (GRCm39) |
missense |
probably benign |
|
|
R9264:Abca15
|
UTSW |
7 |
120,001,056 (GRCm39) |
missense |
probably benign |
0.14 |
|
R9517:Abca15
|
UTSW |
7 |
119,987,424 (GRCm39) |
missense |
probably benign |
0.07 |
|
RF018:Abca15
|
UTSW |
7 |
119,993,683 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
Z1176:Abca15
|
UTSW |
7 |
119,981,728 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Z1176:Abca15
|
UTSW |
7 |
119,945,249 (GRCm39) |
missense |
probably benign |
0.22 |
|
| Predicted Primers |
PCR Primer
(F):5'- CATGTATCACCAAAGAGGGGCACAG -3'
(R):5'- TTCGACCTCCCACATAAGTTCATGC -3'
Sequencing Primer
(F):5'- AGGACAGTGCTAGACATCTTC -3'
(R):5'- CACATAAGTTCATGCCACATTTTC -3'
|
| Posted On |
2014-04-13 |
Incidental Mutation