Incidental Mutation 'R1497:Tanc2'
| ID |
168981 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Tanc2
|
| Ensembl Gene |
ENSMUSG00000053580 |
| Gene Name |
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 |
| Synonyms |
5730590C14Rik, 3526402J09Rik |
| MMRRC Submission |
039548-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R1497 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
11 |
| Chromosomal Location |
105480812-105820130 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 105812963 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Aspartic acid
at position 1469
(V1469D)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000097904
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000100330]
|
| AlphaFold |
A2A690 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000089485
|
| SMART Domains |
Protein: ENSMUSP00000086912
Gene: ENSMUSG00000053580
| Domain | Start | End | E-Value | Type |
|---|
|
ANK
|
35 |
63 |
1.16e3 |
SMART |
|
ANK
|
78 |
107 |
3.31e-1 |
SMART |
|
ANK
|
111 |
140 |
7.71e-2 |
SMART |
|
ANK
|
144 |
173 |
6.12e-5 |
SMART |
|
ANK
|
177 |
206 |
8.99e-3 |
SMART |
|
ANK
|
210 |
239 |
5.71e-5 |
SMART |
|
ANK
|
243 |
272 |
2.11e2 |
SMART |
|
Blast:TPR
|
289 |
322 |
3e-14 |
BLAST |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000100330
AA Change: V1469D
PolyPhen 2
Score 0.208 (Sensitivity: 0.92; Specificity: 0.88)
|
| SMART Domains |
Protein: ENSMUSP00000097904
Gene: ENSMUSG00000053580
AA Change: V1469D
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
32 |
50 |
N/A |
INTRINSIC |
|
low complexity region
|
129 |
152 |
N/A |
INTRINSIC |
|
low complexity region
|
362 |
375 |
N/A |
INTRINSIC |
|
low complexity region
|
436 |
447 |
N/A |
INTRINSIC |
|
low complexity region
|
823 |
834 |
N/A |
INTRINSIC |
|
ANK
|
846 |
878 |
2.08e3 |
SMART |
|
ANK
|
882 |
913 |
2.97e2 |
SMART |
|
ANK
|
917 |
946 |
5.75e-1 |
SMART |
|
ANK
|
950 |
979 |
8.62e1 |
SMART |
|
ANK
|
990 |
1018 |
1.16e3 |
SMART |
|
ANK
|
1033 |
1062 |
3.31e-1 |
SMART |
|
ANK
|
1066 |
1095 |
7.71e-2 |
SMART |
|
ANK
|
1099 |
1128 |
6.12e-5 |
SMART |
|
ANK
|
1132 |
1161 |
8.99e-3 |
SMART |
|
ANK
|
1165 |
1194 |
5.71e-5 |
SMART |
|
ANK
|
1198 |
1227 |
2.11e2 |
SMART |
|
TPR
|
1244 |
1277 |
3.89e1 |
SMART |
|
TPR
|
1291 |
1324 |
3.61e-2 |
SMART |
|
TPR
|
1325 |
1358 |
2.82e-4 |
SMART |
|
low complexity region
|
1369 |
1406 |
N/A |
INTRINSIC |
|
low complexity region
|
1533 |
1539 |
N/A |
INTRINSIC |
|
low complexity region
|
1787 |
1802 |
N/A |
INTRINSIC |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000146162
AA Change: V611D
|
| SMART Domains |
Protein: ENSMUSP00000123674
Gene: ENSMUSG00000053580
AA Change: V611D
| Domain | Start | End | E-Value | Type |
|---|
|
ANK
|
15 |
46 |
2.97e2 |
SMART |
|
ANK
|
50 |
79 |
5.75e-1 |
SMART |
|
ANK
|
83 |
112 |
8.62e1 |
SMART |
|
ANK
|
123 |
151 |
1.16e3 |
SMART |
|
ANK
|
166 |
195 |
3.31e-1 |
SMART |
|
ANK
|
199 |
228 |
7.71e-2 |
SMART |
|
ANK
|
232 |
261 |
6.12e-5 |
SMART |
|
ANK
|
265 |
294 |
8.99e-3 |
SMART |
|
ANK
|
298 |
327 |
5.71e-5 |
SMART |
|
ANK
|
331 |
360 |
3.44e1 |
SMART |
|
TPR
|
387 |
420 |
3.89e1 |
SMART |
|
TPR
|
434 |
467 |
3.61e-2 |
SMART |
|
TPR
|
468 |
501 |
2.82e-4 |
SMART |
|
low complexity region
|
512 |
549 |
N/A |
INTRINSIC |
|
low complexity region
|
676 |
682 |
N/A |
INTRINSIC |
|
low complexity region
|
930 |
945 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.0630 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.4%
- 10x: 96.8%
- 20x: 94.4%
|
| Validation Efficiency |
99% (79/80) |
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a gene trap vector die prior to E12. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 79 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca8b |
G |
T |
11: 109,864,647 (GRCm39) |
|
probably benign |
Het |
| Abhd17a |
A |
G |
10: 80,420,164 (GRCm39) |
|
probably benign |
Het |
| Acacb |
G |
A |
5: 114,334,868 (GRCm39) |
E646K |
probably damaging |
Het |
| Afap1l2 |
T |
C |
19: 56,916,743 (GRCm39) |
M262V |
probably benign |
Het |
| Anapc7 |
T |
A |
5: 122,573,578 (GRCm39) |
|
probably benign |
Het |
| Car5b |
T |
A |
X: 162,771,400 (GRCm39) |
K188N |
probably benign |
Het |
| Caskin1 |
C |
T |
17: 24,723,515 (GRCm39) |
R768* |
probably null |
Het |
| Casp8ap2 |
T |
C |
4: 32,639,938 (GRCm39) |
S331P |
probably benign |
Het |
| Ccdc68 |
C |
T |
18: 70,093,585 (GRCm39) |
|
probably benign |
Het |
| Cd44 |
A |
T |
2: 102,673,300 (GRCm39) |
|
probably null |
Het |
| Celsr3 |
A |
G |
9: 108,726,064 (GRCm39) |
S3090G |
probably benign |
Het |
| Clasp1 |
A |
T |
1: 118,479,788 (GRCm39) |
M1023L |
probably benign |
Het |
| Clec16a |
T |
C |
16: 10,453,123 (GRCm39) |
F608S |
probably damaging |
Het |
| Col7a1 |
A |
C |
9: 108,807,893 (GRCm39) |
E2531A |
unknown |
Het |
| Ctc1 |
T |
A |
11: 68,913,387 (GRCm39) |
C128S |
probably benign |
Het |
| Cyp2d41-ps |
T |
C |
15: 82,666,223 (GRCm39) |
|
noncoding transcript |
Het |
| Cyp2j6 |
T |
A |
4: 96,419,898 (GRCm39) |
I278F |
probably damaging |
Het |
| Dhtkd1 |
A |
T |
2: 5,908,924 (GRCm39) |
S723R |
probably damaging |
Het |
| Dhx8 |
A |
G |
11: 101,626,213 (GRCm39) |
|
probably benign |
Het |
| Dnah17 |
A |
T |
11: 118,005,059 (GRCm39) |
L775Q |
probably damaging |
Het |
| Dnah8 |
C |
A |
17: 30,971,049 (GRCm39) |
T2701K |
probably damaging |
Het |
| Eml3 |
T |
A |
19: 8,913,733 (GRCm39) |
S424R |
probably damaging |
Het |
| Epm2aip1 |
A |
G |
9: 111,101,315 (GRCm39) |
E96G |
possibly damaging |
Het |
| Ezr |
T |
C |
17: 7,010,107 (GRCm39) |
H314R |
probably benign |
Het |
| Fam193b |
G |
T |
13: 55,702,247 (GRCm39) |
H43Q |
probably damaging |
Het |
| Fam217a |
T |
A |
13: 35,095,195 (GRCm39) |
N340I |
probably damaging |
Het |
| Fcrl1 |
A |
T |
3: 87,292,109 (GRCm39) |
Q89H |
probably damaging |
Het |
| Flg2 |
A |
T |
3: 93,127,076 (GRCm39) |
H1996L |
unknown |
Het |
| Gabpb1 |
C |
T |
2: 126,481,169 (GRCm39) |
V327M |
possibly damaging |
Het |
| Gtf3c3 |
A |
G |
1: 54,477,098 (GRCm39) |
V36A |
probably benign |
Het |
| Hspg2 |
A |
G |
4: 137,275,407 (GRCm39) |
N2739S |
probably damaging |
Het |
| Hyal1 |
A |
G |
9: 107,455,194 (GRCm39) |
|
probably null |
Het |
| Ipo13 |
T |
C |
4: 117,761,856 (GRCm39) |
D448G |
probably benign |
Het |
| Kcnq5 |
T |
C |
1: 21,472,610 (GRCm39) |
D860G |
possibly damaging |
Het |
| Kif13b |
A |
G |
14: 64,973,715 (GRCm39) |
N355S |
probably damaging |
Het |
| Kmt2c |
T |
A |
5: 25,519,513 (GRCm39) |
H2199L |
possibly damaging |
Het |
| Magi1 |
A |
G |
6: 93,724,310 (GRCm39) |
F235S |
probably damaging |
Het |
| Maml1 |
A |
C |
11: 50,156,534 (GRCm39) |
M547R |
possibly damaging |
Het |
| Mapk7 |
T |
C |
11: 61,384,689 (GRCm39) |
K6E |
possibly damaging |
Het |
| Mbd5 |
T |
A |
2: 49,147,393 (GRCm39) |
N534K |
possibly damaging |
Het |
| Mcat |
G |
A |
15: 83,433,453 (GRCm39) |
Q34* |
probably null |
Het |
| Mcu |
T |
A |
10: 59,284,670 (GRCm39) |
D180V |
probably damaging |
Het |
| Mettl21c |
G |
T |
1: 44,048,951 (GRCm39) |
P199T |
probably benign |
Het |
| Mndal |
A |
T |
1: 173,700,441 (GRCm39) |
S177T |
probably benign |
Het |
| Mpeg1 |
G |
T |
19: 12,438,611 (GRCm39) |
C23F |
probably benign |
Het |
| Mup15 |
T |
A |
4: 61,356,471 (GRCm39) |
Y98F |
probably benign |
Het |
| Myh8 |
T |
C |
11: 67,180,638 (GRCm39) |
S625P |
probably benign |
Het |
| Nipsnap2 |
T |
C |
5: 129,830,282 (GRCm39) |
|
probably benign |
Het |
| Nlrp4e |
T |
C |
7: 23,019,797 (GRCm39) |
S95P |
probably benign |
Het |
| Or1e19 |
T |
A |
11: 73,316,653 (GRCm39) |
D52V |
possibly damaging |
Het |
| Or4a66 |
T |
C |
2: 88,531,106 (GRCm39) |
D189G |
probably damaging |
Het |
| Otop2 |
A |
G |
11: 115,220,675 (GRCm39) |
|
probably null |
Het |
| Pcnx4 |
G |
C |
12: 72,621,174 (GRCm39) |
G998A |
probably benign |
Het |
| Pnkd |
C |
A |
1: 74,390,681 (GRCm39) |
|
probably null |
Het |
| Ppp4r4 |
T |
A |
12: 103,573,204 (GRCm39) |
V701E |
probably benign |
Het |
| Ryr2 |
A |
G |
13: 11,616,727 (GRCm39) |
I3897T |
probably damaging |
Het |
| Scn1a |
T |
C |
2: 66,162,631 (GRCm39) |
E205G |
probably damaging |
Het |
| Sdk2 |
G |
A |
11: 113,784,401 (GRCm39) |
|
probably benign |
Het |
| Serpinb5 |
A |
T |
1: 106,803,782 (GRCm39) |
Q156L |
probably benign |
Het |
| Setdb1 |
A |
T |
3: 95,234,778 (GRCm39) |
V975D |
probably benign |
Het |
| Shc1 |
A |
G |
3: 89,335,752 (GRCm39) |
*470W |
probably null |
Het |
| Sik3 |
T |
A |
9: 46,113,320 (GRCm39) |
V587E |
probably damaging |
Het |
| Sik3 |
C |
A |
9: 46,132,387 (GRCm39) |
H1276Q |
probably benign |
Het |
| Spata7 |
T |
C |
12: 98,635,120 (GRCm39) |
I384T |
probably damaging |
Het |
| Tasor2 |
T |
C |
13: 3,620,409 (GRCm39) |
E2164G |
probably damaging |
Het |
| Tdrd5 |
A |
T |
1: 156,083,372 (GRCm39) |
N888K |
probably benign |
Het |
| Tex22 |
T |
C |
12: 113,039,000 (GRCm39) |
S34P |
probably benign |
Het |
| Tmed6 |
T |
C |
8: 107,790,754 (GRCm39) |
T98A |
probably benign |
Het |
| Trim66 |
G |
A |
7: 109,083,826 (GRCm39) |
P141L |
probably benign |
Het |
| Trpa1 |
T |
C |
1: 14,956,036 (GRCm39) |
I778V |
probably benign |
Het |
| Urb2 |
T |
A |
8: 124,754,816 (GRCm39) |
H174Q |
probably damaging |
Het |
| Usb1 |
T |
C |
8: 96,065,325 (GRCm39) |
V59A |
probably benign |
Het |
| Vmn1r11 |
T |
A |
6: 57,114,394 (GRCm39) |
N19K |
probably damaging |
Het |
| Vmn1r185 |
A |
T |
7: 26,311,219 (GRCm39) |
F95L |
probably benign |
Het |
| Vmn1r206 |
C |
T |
13: 22,805,160 (GRCm39) |
V16M |
probably benign |
Het |
| Vmn2r92 |
T |
C |
17: 18,387,625 (GRCm39) |
V210A |
probably benign |
Het |
| Wdr17 |
A |
T |
8: 55,125,536 (GRCm39) |
I448K |
possibly damaging |
Het |
| Zfp768 |
T |
A |
7: 126,942,733 (GRCm39) |
Q465L |
probably damaging |
Het |
| Zfp804b |
T |
A |
5: 6,821,105 (GRCm39) |
N617Y |
probably damaging |
Het |
|
| Other mutations in Tanc2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00501:Tanc2
|
APN |
11 |
105,814,046 (GRCm39) |
missense |
probably benign |
0.28 |
|
IGL00688:Tanc2
|
APN |
11 |
105,689,516 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00709:Tanc2
|
APN |
11 |
105,689,621 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01013:Tanc2
|
APN |
11 |
105,515,891 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL01141:Tanc2
|
APN |
11 |
105,777,300 (GRCm39) |
splice site |
probably benign |
|
|
IGL01386:Tanc2
|
APN |
11 |
105,777,207 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01433:Tanc2
|
APN |
11 |
105,701,348 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
IGL01562:Tanc2
|
APN |
11 |
105,670,895 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01979:Tanc2
|
APN |
11 |
105,667,746 (GRCm39) |
missense |
probably benign |
|
|
IGL02104:Tanc2
|
APN |
11 |
105,670,959 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02434:Tanc2
|
APN |
11 |
105,670,868 (GRCm39) |
missense |
probably benign |
0.14 |
|
IGL02534:Tanc2
|
APN |
11 |
105,725,994 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02568:Tanc2
|
APN |
11 |
105,667,777 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03279:Tanc2
|
APN |
11 |
105,803,918 (GRCm39) |
splice site |
probably null |
|
|
R0595:Tanc2
|
UTSW |
11 |
105,605,003 (GRCm39) |
splice site |
probably null |
|
|
R1131:Tanc2
|
UTSW |
11 |
105,725,828 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1320:Tanc2
|
UTSW |
11 |
105,777,270 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1487:Tanc2
|
UTSW |
11 |
105,814,460 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1692:Tanc2
|
UTSW |
11 |
105,748,326 (GRCm39) |
missense |
probably benign |
|
|
R1712:Tanc2
|
UTSW |
11 |
105,790,606 (GRCm39) |
missense |
probably benign |
|
|
R1793:Tanc2
|
UTSW |
11 |
105,515,859 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R1812:Tanc2
|
UTSW |
11 |
105,777,212 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1905:Tanc2
|
UTSW |
11 |
105,813,689 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R1959:Tanc2
|
UTSW |
11 |
105,801,121 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1962:Tanc2
|
UTSW |
11 |
105,689,558 (GRCm39) |
missense |
probably benign |
0.14 |
|
R2122:Tanc2
|
UTSW |
11 |
105,786,775 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2174:Tanc2
|
UTSW |
11 |
105,801,135 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2341:Tanc2
|
UTSW |
11 |
105,725,877 (GRCm39) |
missense |
probably benign |
0.09 |
|
R2497:Tanc2
|
UTSW |
11 |
105,564,319 (GRCm39) |
critical splice donor site |
probably null |
|
|
R3438:Tanc2
|
UTSW |
11 |
105,748,401 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R3711:Tanc2
|
UTSW |
11 |
105,689,516 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3765:Tanc2
|
UTSW |
11 |
105,805,796 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3890:Tanc2
|
UTSW |
11 |
105,689,504 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4193:Tanc2
|
UTSW |
11 |
105,804,888 (GRCm39) |
intron |
probably benign |
|
|
R4609:Tanc2
|
UTSW |
11 |
105,801,066 (GRCm39) |
missense |
probably benign |
0.24 |
|
R4674:Tanc2
|
UTSW |
11 |
105,758,306 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4928:Tanc2
|
UTSW |
11 |
105,758,588 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5008:Tanc2
|
UTSW |
11 |
105,515,886 (GRCm39) |
start codon destroyed |
probably null |
0.46 |
|
R5010:Tanc2
|
UTSW |
11 |
105,670,918 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5135:Tanc2
|
UTSW |
11 |
105,748,379 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R5385:Tanc2
|
UTSW |
11 |
105,667,672 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5409:Tanc2
|
UTSW |
11 |
105,758,311 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R5419:Tanc2
|
UTSW |
11 |
105,813,709 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5501:Tanc2
|
UTSW |
11 |
105,805,811 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5590:Tanc2
|
UTSW |
11 |
105,814,132 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5651:Tanc2
|
UTSW |
11 |
105,689,526 (GRCm39) |
missense |
probably benign |
0.44 |
|
R5798:Tanc2
|
UTSW |
11 |
105,812,681 (GRCm39) |
small deletion |
probably benign |
|
|
R5876:Tanc2
|
UTSW |
11 |
105,813,439 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R5889:Tanc2
|
UTSW |
11 |
105,812,633 (GRCm39) |
missense |
probably benign |
0.23 |
|
R5958:Tanc2
|
UTSW |
11 |
105,731,451 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5999:Tanc2
|
UTSW |
11 |
105,758,543 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6024:Tanc2
|
UTSW |
11 |
105,814,498 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6024:Tanc2
|
UTSW |
11 |
105,758,543 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6025:Tanc2
|
UTSW |
11 |
105,787,373 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R6025:Tanc2
|
UTSW |
11 |
105,758,543 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6048:Tanc2
|
UTSW |
11 |
105,758,543 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6049:Tanc2
|
UTSW |
11 |
105,758,543 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6185:Tanc2
|
UTSW |
11 |
105,803,865 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6335:Tanc2
|
UTSW |
11 |
105,748,382 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6821:Tanc2
|
UTSW |
11 |
105,777,316 (GRCm39) |
splice site |
probably null |
|
|
R6846:Tanc2
|
UTSW |
11 |
105,689,479 (GRCm39) |
missense |
probably benign |
0.34 |
|
R6857:Tanc2
|
UTSW |
11 |
105,801,114 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R6904:Tanc2
|
UTSW |
11 |
105,726,056 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R7009:Tanc2
|
UTSW |
11 |
105,731,525 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R7017:Tanc2
|
UTSW |
11 |
105,813,934 (GRCm39) |
missense |
probably benign |
|
|
R7371:Tanc2
|
UTSW |
11 |
105,689,422 (GRCm39) |
missense |
probably benign |
|
|
R7556:Tanc2
|
UTSW |
11 |
105,799,857 (GRCm39) |
missense |
|
|
|
R7630:Tanc2
|
UTSW |
11 |
105,667,734 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7693:Tanc2
|
UTSW |
11 |
105,814,293 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7757:Tanc2
|
UTSW |
11 |
105,667,684 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R7807:Tanc2
|
UTSW |
11 |
105,758,480 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7878:Tanc2
|
UTSW |
11 |
105,804,241 (GRCm39) |
missense |
|
|
|
R7895:Tanc2
|
UTSW |
11 |
105,812,651 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7952:Tanc2
|
UTSW |
11 |
105,787,423 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8099:Tanc2
|
UTSW |
11 |
105,754,833 (GRCm39) |
missense |
probably benign |
0.17 |
|
R8117:Tanc2
|
UTSW |
11 |
105,725,988 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8133:Tanc2
|
UTSW |
11 |
105,814,048 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8422:Tanc2
|
UTSW |
11 |
105,726,014 (GRCm39) |
missense |
probably benign |
0.10 |
|
R8527:Tanc2
|
UTSW |
11 |
105,807,834 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8542:Tanc2
|
UTSW |
11 |
105,807,834 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8834:Tanc2
|
UTSW |
11 |
105,807,845 (GRCm39) |
missense |
|
|
|
R8912:Tanc2
|
UTSW |
11 |
105,758,153 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8927:Tanc2
|
UTSW |
11 |
105,701,331 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8928:Tanc2
|
UTSW |
11 |
105,701,331 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8968:Tanc2
|
UTSW |
11 |
105,758,400 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R9065:Tanc2
|
UTSW |
11 |
105,689,518 (GRCm39) |
nonsense |
probably null |
|
|
R9095:Tanc2
|
UTSW |
11 |
105,758,104 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9108:Tanc2
|
UTSW |
11 |
105,810,580 (GRCm39) |
intron |
probably benign |
|
|
R9131:Tanc2
|
UTSW |
11 |
105,689,603 (GRCm39) |
missense |
probably benign |
|
|
R9294:Tanc2
|
UTSW |
11 |
105,777,284 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9445:Tanc2
|
UTSW |
11 |
105,758,290 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
X0027:Tanc2
|
UTSW |
11 |
105,726,009 (GRCm39) |
missense |
probably benign |
0.26 |
|
| Predicted Primers |
PCR Primer
(F):5'- CTATGTCCCAACAACCGTGAGATCC -3'
(R):5'- AAGATGCACCCTGATGAGCTGGAG -3'
Sequencing Primer
(F):5'- GATgcagcagcagcagc -3'
(R):5'- CCCTGATGAGCTGGAGAAGTATG -3'
|
| Posted On |
2014-04-13 |
Incidental Mutation