Mutagenetix > Incidental Mutation

Incidental Mutation 'R1550:Stab2'

169859

Institutional Source

Beutler Lab

Gene Symbol

Stab2

Ensembl Gene

ENSMUSG00000035459

Gene Name

stabilin 2

Synonyms

FEEL-2, STAB-2

MMRRC Submission

039589-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R1550 (G1)

Quality Score

208

Status

Not validated

Chromosome

Chromosomal Location

86677062-86843889 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to T at 86714790 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Phenylalanine to Leucine at position 125 (F125L)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000035288]

AlphaFold

Q8R4U0

Predicted Effect

probably benign
Transcript: ENSMUST00000035288
AA Change: F1576L

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)

SMART Domains

Protein: ENSMUSP00000048309
Gene: ENSMUSG00000035459
AA Change: F1576L

Domain	Start	End	E-Value	Type
signal peptide	1	27	N/A	INTRINSIC
EGF	119	156	1.85e0	SMART
EGF	167	201	2.43e1	SMART
EGF	206	244	1.43e-1	SMART
EGF	248	284	3.82e-2	SMART
EGF	333	370	2.02e-1	SMART
FAS1	414	515	1.06e-8	SMART
FAS1	561	662	3.54e-19	SMART
EGF	746	783	6.76e-3	SMART
EGF	836	873	1.31e0	SMART
EGF	877	917	2.99e-4	SMART
EGF	921	960	3.51e-1	SMART
EGF	964	1002	1.99e0	SMART
FAS1	1038	1138	1.73e-13	SMART
FAS1	1181	1276	1.83e-12	SMART
EGF	1354	1391	6.92e0	SMART
EGF	1401	1435	1.11e1	SMART
EGF	1442	1477	3.01e0	SMART
EGF	1481	1519	1.64e-1	SMART
EGF	1523	1561	1.14e0	SMART
EGF	1565	1603	5.62e0	SMART
FAS1	1638	1734	2.23e-25	SMART
FAS1	1785	1891	6.92e-22	SMART
EGF	1966	2006	1.95e1	SMART
EGF_like	1977	2017	2.46e-1	SMART
EGF	2016	2050	1.14e0	SMART
EGF	2058	2089	1.56e1	SMART
EGF	2093	2130	1.36e1	SMART
EGF	2134	2173	2.13e0	SMART
LINK	2204	2298	2.08e-29	SMART
FAS1	2363	2455	3.19e-12	SMART
transmembrane domain	2467	2489	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000159023

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000159118

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000159445

Predicted Effect

probably benign
Transcript: ENSMUST00000161560
AA Change: F125L

PolyPhen 2 Score 0.008 (Sensitivity: 0.96; Specificity: 0.76)

SMART Domains

Protein: ENSMUSP00000125263
Gene: ENSMUSG00000035459
AA Change: F125L

Domain	Start	End	E-Value	Type
EGF	30	68	1.64e-1	SMART
EGF	72	110	1.14e0	SMART
EGF	114	152	5.62e0	SMART
FAS1	187	283	2.23e-25	SMART
FAS1	334	440	6.92e-22	SMART
EGF	515	555	1.95e1	SMART
EGF_like	526	566	2.46e-1	SMART
EGF	565	599	1.14e0	SMART
EGF	607	638	1.56e1	SMART
EGF	643	680	1.36e1	SMART
EGF	684	723	2.13e0	SMART
LINK	754	848	2.08e-29	SMART

Predicted Effect

unknown
Transcript: ENSMUST00000219341
AA Change: F124L

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000219612

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000219659

Coding Region Coverage

1x: 99.0%
3x: 98.1%
10x: 95.4%
20x: 89.2%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a large, transmembrane receptor protein which may function in angiogenesis, lymphocyte homing, cell adhesion, or receptor scavenging. The protein contains 7 fasciclin, 15 epidermal growth factor (EGF)-like, and 2 laminin-type EGF-like domains as well as a C-type lectin-like hyaluronan-binding Link module. The protein is primarily expressed on sinusoidal endothelial cells of liver, spleen, and lymph node. The receptor has been shown to bind and endocytose ligands such as hyaluronan, low density lipoprotein, Gram-positive and Gram-negative bacteria, and advanced glycosylation end products. Supporting its possible role as a scavenger receptor, the protein has been shown to cycle between the plasma membrane and lysosomes. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mice homozygous for knock-out alleles exhibit no gross abnormaities. Mice homozygous for one null allele display elevated serum hyaluronic acid levels and decreased metastasis. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 61 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abcc6	A	G	7: 45,654,668 (GRCm39)	V551A	probably benign	Het
Acss1	A	T	2: 150,484,715 (GRCm39)	L176Q	probably damaging	Het
Aldh7a1	A	G	18: 56,683,454 (GRCm39)	I117T	possibly damaging	Het
Arf5	C	T	6: 28,426,152 (GRCm39)	R180C	probably damaging	Het
Arhgap21	A	T	2: 20,886,576 (GRCm39)	Y39*	probably null	Het
Arrdc1	A	G	2: 24,816,351 (GRCm39)	L206P	probably damaging	Het
Cby3	A	T	11: 50,250,313 (GRCm39)	Y173F	probably damaging	Het
Cdh18	T	A	15: 23,436,634 (GRCm39)	C497S	probably damaging	Het
Cyp11b2	T	C	15: 74,725,442 (GRCm39)	I226V	probably benign	Het
Ddit4l	T	A	3: 137,330,036 (GRCm39)		probably null	Het
Ddx11	C	T	17: 66,445,215 (GRCm39)	T405I	probably benign	Het
Dhx40	A	T	11: 86,667,565 (GRCm39)		probably null	Het
Dlgap2	A	G	8: 14,872,499 (GRCm39)	D659G	probably damaging	Het
Eef2	A	G	10: 81,016,681 (GRCm39)	E586G	probably benign	Het
Fam161a	A	G	11: 22,970,470 (GRCm39)	Q216R	possibly damaging	Het
Fbxw24	G	T	9: 109,436,112 (GRCm39)	R307S	probably benign	Het
Gbp2b	G	T	3: 142,312,591 (GRCm39)	A325S	probably damaging	Het
Gli1	A	T	10: 127,174,385 (GRCm39)	F2Y	probably damaging	Het
Gnl2	T	C	4: 124,938,027 (GRCm39)	V269A	probably damaging	Het
Grin1	A	G	2: 25,195,143 (GRCm39)	V292A	probably benign	Het
Heg1	T	A	16: 33,555,923 (GRCm39)	V1001E	probably damaging	Het
Herc2	T	A	7: 55,785,406 (GRCm39)	I1552N	probably damaging	Het
Htr1a	A	G	13: 105,581,788 (GRCm39)	T343A	probably benign	Het
Itk	G	T	11: 46,280,153 (GRCm39)	R29S	probably damaging	Het
Ivns1abp	G	T	1: 151,237,242 (GRCm39)	G469C	probably damaging	Het
Jph3	A	T	8: 122,511,598 (GRCm39)	N529Y	possibly damaging	Het
Kdm2b	A	G	5: 123,019,120 (GRCm39)	L829P	probably damaging	Het
Kprp	T	A	3: 92,732,033 (GRCm39)	Y339F	probably damaging	Het
Lrp2	A	G	2: 69,333,005 (GRCm39)	V1504A	possibly damaging	Het
Lypd6b	A	G	2: 49,833,615 (GRCm39)	D85G	probably damaging	Het
Mansc4	T	C	6: 146,977,136 (GRCm39)	Y160C	probably damaging	Het
Mgll	C	A	6: 88,790,871 (GRCm39)	H164N	probably benign	Het
Mtmr4	A	T	11: 87,504,342 (GRCm39)	D1097V	probably damaging	Het
Nfasc	T	C	1: 132,536,241 (GRCm39)	K571E	probably damaging	Het
Nfat5	A	T	8: 108,097,205 (GRCm39)	N1527Y	probably damaging	Het
Nlgn1	A	G	3: 25,966,808 (GRCm39)	L215P	probably damaging	Het
Or6b9	T	A	7: 106,555,235 (GRCm39)	I303L	probably benign	Het
Pde4dip	T	C	3: 97,627,020 (GRCm39)	S1173G	probably damaging	Het
Prrt3	A	T	6: 113,472,468 (GRCm39)	V568E	probably damaging	Het
Ptpra	G	A	2: 130,383,313 (GRCm39)	R503Q	possibly damaging	Het
Pttg1ip2	C	A	5: 5,502,019 (GRCm39)	W144C	probably benign	Het
Rnf7l	A	G	10: 63,257,427 (GRCm39)	L31P	probably damaging	Het
Sema5a	G	A	15: 32,618,995 (GRCm39)	A508T	probably benign	Het
Serpinb11	T	C	1: 107,307,418 (GRCm39)	I283T	possibly damaging	Het
Setbp1	A	T	18: 78,901,807 (GRCm39)	L620Q	probably damaging	Het
Sipa1l3	A	T	7: 29,082,628 (GRCm39)	C756S	probably benign	Het
Sirpa	A	T	2: 129,471,961 (GRCm39)	I463F	probably damaging	Het
Slc13a2	G	T	11: 78,293,990 (GRCm39)	N257K	probably damaging	Het
Slc4a5	C	A	6: 83,248,039 (GRCm39)	T530N	probably damaging	Het
Tet2	G	T	3: 133,175,280 (GRCm39)	Q1356K	probably benign	Het
Tet3	A	T	6: 83,363,010 (GRCm39)	S856T	probably damaging	Het
Tg	C	T	15: 66,565,279 (GRCm39)	T1207I	possibly damaging	Het
Tkt	A	G	14: 30,287,525 (GRCm39)	Y173C	probably damaging	Het
Tlr6	T	A	5: 65,110,754 (GRCm39)	I718F	probably damaging	Het
Tnfrsf11b	A	G	15: 54,117,454 (GRCm39)	V267A	possibly damaging	Het
Ubqln3	T	A	7: 103,790,753 (GRCm39)	N446Y	probably damaging	Het
Vmn2r118	C	T	17: 55,915,083 (GRCm39)	C521Y	probably damaging	Het
Vps16	A	G	2: 130,282,260 (GRCm39)	D394G	probably benign	Het
Zfp236	A	T	18: 82,692,549 (GRCm39)	M142K	possibly damaging	Het
Zfp780b	T	C	7: 27,664,282 (GRCm39)	D91G	probably benign	Het
Zfp97	T	A	17: 17,365,468 (GRCm39)	Y322*	probably null	Het

Other mutations in Stab2

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00091:Stab2	APN	10	86,705,070 (GRCm39)	splice site	probably null
IGL00809:Stab2	APN	10	86,684,038 (GRCm39)	splice site	probably benign
IGL00911:Stab2	APN	10	86,805,617 (GRCm39)	missense	probably damaging	1.00
IGL01347:Stab2	APN	10	86,737,567 (GRCm39)	splice site	probably null
IGL01411:Stab2	APN	10	86,815,872 (GRCm39)	splice site	probably benign
IGL01503:Stab2	APN	10	86,776,477 (GRCm39)	splice site	probably benign
IGL01599:Stab2	APN	10	86,758,759 (GRCm39)	missense	probably damaging	1.00
IGL01635:Stab2	APN	10	86,816,992 (GRCm39)	missense	probably benign	0.04
IGL01640:Stab2	APN	10	86,790,035 (GRCm39)	missense	probably benign	0.09
IGL01671:Stab2	APN	10	86,805,141 (GRCm39)	missense	possibly damaging	0.80
IGL02023:Stab2	APN	10	86,707,695 (GRCm39)	missense	possibly damaging	0.67
IGL02075:Stab2	APN	10	86,803,514 (GRCm39)	missense	possibly damaging	0.71
IGL02174:Stab2	APN	10	86,695,606 (GRCm39)	splice site	probably null
IGL02600:Stab2	APN	10	86,790,123 (GRCm39)	missense	probably damaging	1.00
IGL02666:Stab2	APN	10	86,686,766 (GRCm39)	missense	possibly damaging	0.67
IGL02668:Stab2	APN	10	86,682,027 (GRCm39)	splice site	probably benign
IGL02709:Stab2	APN	10	86,682,029 (GRCm39)	splice site	probably benign
IGL02728:Stab2	APN	10	86,692,420 (GRCm39)	missense	possibly damaging	0.95
IGL02803:Stab2	APN	10	86,786,133 (GRCm39)	splice site	probably benign
IGL02938:Stab2	APN	10	86,707,785 (GRCm39)	missense	possibly damaging	0.77
IGL03033:Stab2	APN	10	86,832,667 (GRCm39)	critical splice donor site	probably null
IGL03238:Stab2	APN	10	86,690,985 (GRCm39)	missense	probably damaging	1.00
IGL03402:Stab2	APN	10	86,805,165 (GRCm39)	missense	probably benign	0.03
prospector	UTSW	10	86,737,431 (GRCm39)	splice site	probably null
songbird	UTSW	10	86,694,016 (GRCm39)	missense	probably damaging	1.00
3-1:Stab2	UTSW	10	86,705,041 (GRCm39)	missense	probably damaging	0.96
F6893:Stab2	UTSW	10	86,691,035 (GRCm39)	missense	probably damaging	1.00
K7371:Stab2	UTSW	10	86,779,153 (GRCm39)	critical splice donor site	probably null
PIT4142001:Stab2	UTSW	10	86,703,039 (GRCm39)	missense	possibly damaging	0.94
PIT4362001:Stab2	UTSW	10	86,697,299 (GRCm39)	nonsense	probably null
R0015:Stab2	UTSW	10	86,679,481 (GRCm39)	missense	probably benign
R0254:Stab2	UTSW	10	86,733,824 (GRCm39)	missense	probably benign
R0310:Stab2	UTSW	10	86,803,477 (GRCm39)	splice site	probably benign
R0333:Stab2	UTSW	10	86,677,491 (GRCm39)	missense	probably benign
R0391:Stab2	UTSW	10	86,783,008 (GRCm39)	missense	probably benign	0.27
R0400:Stab2	UTSW	10	86,708,474 (GRCm39)	missense	probably damaging	1.00
R0433:Stab2	UTSW	10	86,679,355 (GRCm39)	splice site	probably benign
R0440:Stab2	UTSW	10	86,785,792 (GRCm39)	missense	probably benign	0.23
R0743:Stab2	UTSW	10	86,723,759 (GRCm39)	missense	probably damaging	1.00
R0847:Stab2	UTSW	10	86,805,735 (GRCm39)	missense	probably benign	0.00
R0883:Stab2	UTSW	10	86,760,314 (GRCm39)	splice site	probably benign
R1078:Stab2	UTSW	10	86,742,997 (GRCm39)	splice site	probably null
R1118:Stab2	UTSW	10	86,721,582 (GRCm39)	splice site	probably null
R1119:Stab2	UTSW	10	86,695,619 (GRCm39)	missense	possibly damaging	0.51
R1179:Stab2	UTSW	10	86,786,165 (GRCm39)	missense	probably damaging	0.98
R1440:Stab2	UTSW	10	86,697,231 (GRCm39)	splice site	probably null
R1616:Stab2	UTSW	10	86,721,582 (GRCm39)	splice site	probably null
R1728:Stab2	UTSW	10	86,773,903 (GRCm39)	missense	probably benign	0.41
R1768:Stab2	UTSW	10	86,838,872 (GRCm39)	missense	probably damaging	1.00
R1772:Stab2	UTSW	10	86,790,098 (GRCm39)	missense	probably benign	0.06
R1776:Stab2	UTSW	10	86,793,680 (GRCm39)	missense	possibly damaging	0.92
R1784:Stab2	UTSW	10	86,773,903 (GRCm39)	missense	probably benign	0.41
R1892:Stab2	UTSW	10	86,773,913 (GRCm39)	missense	probably damaging	0.99
R1957:Stab2	UTSW	10	86,697,334 (GRCm39)	missense	probably benign	0.13
R1972:Stab2	UTSW	10	86,796,180 (GRCm39)	missense	probably damaging	0.99
R1975:Stab2	UTSW	10	86,732,360 (GRCm39)	critical splice donor site	probably null
R1976:Stab2	UTSW	10	86,732,360 (GRCm39)	critical splice donor site	probably null
R1996:Stab2	UTSW	10	86,838,895 (GRCm39)	missense	probably damaging	1.00
R2085:Stab2	UTSW	10	86,790,023 (GRCm39)	missense	probably damaging	1.00
R2149:Stab2	UTSW	10	86,700,904 (GRCm39)	nonsense	probably null
R2169:Stab2	UTSW	10	86,723,726 (GRCm39)	missense	probably damaging	1.00
R2201:Stab2	UTSW	10	86,776,503 (GRCm39)	missense	probably benign	0.22
R2296:Stab2	UTSW	10	86,790,338 (GRCm39)	critical splice acceptor site	probably null
R2297:Stab2	UTSW	10	86,790,338 (GRCm39)	critical splice acceptor site	probably null
R2298:Stab2	UTSW	10	86,790,338 (GRCm39)	critical splice acceptor site	probably null
R2326:Stab2	UTSW	10	86,790,338 (GRCm39)	critical splice acceptor site	probably null
R2434:Stab2	UTSW	10	86,805,183 (GRCm39)	missense	possibly damaging	0.78
R2519:Stab2	UTSW	10	86,770,704 (GRCm39)	splice site	probably benign
R2696:Stab2	UTSW	10	86,697,363 (GRCm39)	missense	probably benign	0.45
R2883:Stab2	UTSW	10	86,803,550 (GRCm39)	missense	possibly damaging	0.92
R2923:Stab2	UTSW	10	86,697,325 (GRCm39)	missense	probably damaging	1.00
R3711:Stab2	UTSW	10	86,702,572 (GRCm39)	missense	probably damaging	1.00
R3787:Stab2	UTSW	10	86,805,141 (GRCm39)	missense	possibly damaging	0.50
R3834:Stab2	UTSW	10	86,785,776 (GRCm39)	missense	possibly damaging	0.87
R3970:Stab2	UTSW	10	86,714,750 (GRCm39)	missense	probably damaging	0.97
R3979:Stab2	UTSW	10	86,699,320 (GRCm39)	missense	possibly damaging	0.56
R4003:Stab2	UTSW	10	86,693,988 (GRCm39)	missense	probably damaging	1.00
R4088:Stab2	UTSW	10	86,758,049 (GRCm39)	missense	probably damaging	1.00
R4151:Stab2	UTSW	10	86,838,847 (GRCm39)	missense	probably benign	0.12
R4190:Stab2	UTSW	10	86,714,808 (GRCm39)	missense	probably damaging	0.98
R4556:Stab2	UTSW	10	86,803,543 (GRCm39)	missense	possibly damaging	0.95
R4773:Stab2	UTSW	10	86,743,235 (GRCm39)	nonsense	probably null
R4825:Stab2	UTSW	10	86,783,011 (GRCm39)	missense	probably benign	0.08
R4865:Stab2	UTSW	10	86,679,364 (GRCm39)	splice site	probably null
R4871:Stab2	UTSW	10	86,778,099 (GRCm39)	missense	probably damaging	0.99
R4943:Stab2	UTSW	10	86,790,026 (GRCm39)	missense	probably damaging	0.99
R4981:Stab2	UTSW	10	86,796,087 (GRCm39)	missense	probably benign
R4994:Stab2	UTSW	10	86,785,771 (GRCm39)	missense	probably benign
R4999:Stab2	UTSW	10	86,773,773 (GRCm39)	missense	probably damaging	0.97
R5061:Stab2	UTSW	10	86,743,249 (GRCm39)	missense	probably damaging	1.00
R5072:Stab2	UTSW	10	86,699,422 (GRCm39)	missense	probably benign	0.23
R5073:Stab2	UTSW	10	86,699,422 (GRCm39)	missense	probably benign	0.23
R5074:Stab2	UTSW	10	86,699,422 (GRCm39)	missense	probably benign	0.23
R5134:Stab2	UTSW	10	86,707,674 (GRCm39)	splice site	probably null
R5213:Stab2	UTSW	10	86,743,061 (GRCm39)	missense	probably damaging	0.99
R5508:Stab2	UTSW	10	86,796,143 (GRCm39)	missense	probably benign	0.01
R5530:Stab2	UTSW	10	86,783,026 (GRCm39)	missense	probably benign	0.04
R5540:Stab2	UTSW	10	86,683,989 (GRCm39)	missense	probably benign	0.30
R5839:Stab2	UTSW	10	86,708,555 (GRCm39)	missense	probably damaging	0.97
R5949:Stab2	UTSW	10	86,805,713 (GRCm39)	missense	possibly damaging	0.87
R6015:Stab2	UTSW	10	86,773,906 (GRCm39)	missense	probably damaging	0.99
R6019:Stab2	UTSW	10	86,838,886 (GRCm39)	missense	probably benign	0.00
R6116:Stab2	UTSW	10	86,743,054 (GRCm39)	missense	probably damaging	1.00
R6131:Stab2	UTSW	10	86,719,642 (GRCm39)	splice site	probably null
R6209:Stab2	UTSW	10	86,758,867 (GRCm39)	missense	possibly damaging	0.94
R6243:Stab2	UTSW	10	86,743,025 (GRCm39)	missense	probably damaging	1.00
R6433:Stab2	UTSW	10	86,737,431 (GRCm39)	splice site	probably null
R6787:Stab2	UTSW	10	86,754,948 (GRCm39)	missense	probably benign	0.07
R6841:Stab2	UTSW	10	86,778,054 (GRCm39)	missense	probably damaging	1.00
R6873:Stab2	UTSW	10	86,697,230 (GRCm39)	critical splice donor site	probably null
R7025:Stab2	UTSW	10	86,686,701 (GRCm39)	missense	probably damaging	1.00
R7043:Stab2	UTSW	10	86,706,110 (GRCm39)	missense	probably damaging	0.99
R7047:Stab2	UTSW	10	86,694,016 (GRCm39)	missense	probably damaging	1.00
R7107:Stab2	UTSW	10	86,741,456 (GRCm39)	missense	possibly damaging	0.96
R7214:Stab2	UTSW	10	86,735,705 (GRCm39)	missense	probably damaging	0.99
R7271:Stab2	UTSW	10	86,838,972 (GRCm39)	splice site	probably null
R7291:Stab2	UTSW	10	86,782,084 (GRCm39)	missense	probably damaging	0.96
R7336:Stab2	UTSW	10	86,805,049 (GRCm39)	nonsense	probably null
R7432:Stab2	UTSW	10	86,721,547 (GRCm39)	missense	probably damaging	0.99
R7580:Stab2	UTSW	10	86,705,028 (GRCm39)	missense	probably benign	0.00
R7622:Stab2	UTSW	10	86,709,766 (GRCm39)	missense	possibly damaging	0.65
R7629:Stab2	UTSW	10	86,719,646 (GRCm39)	critical splice donor site	probably null
R7658:Stab2	UTSW	10	86,816,999 (GRCm39)	missense	probably benign	0.12
R7798:Stab2	UTSW	10	86,793,776 (GRCm39)	missense	probably damaging	0.98
R7835:Stab2	UTSW	10	86,708,483 (GRCm39)	missense	probably benign	0.06
R7845:Stab2	UTSW	10	86,832,758 (GRCm39)	missense	probably benign	0.09
R7863:Stab2	UTSW	10	86,808,745 (GRCm39)	missense	probably benign	0.30
R7885:Stab2	UTSW	10	86,714,776 (GRCm39)	missense	probably benign	0.03
R7904:Stab2	UTSW	10	86,790,056 (GRCm39)	nonsense	probably null
R7947:Stab2	UTSW	10	86,681,897 (GRCm39)	missense	probably benign	0.31
R7963:Stab2	UTSW	10	86,683,887 (GRCm39)	critical splice donor site	probably null
R8014:Stab2	UTSW	10	86,686,767 (GRCm39)	missense	possibly damaging	0.78
R8021:Stab2	UTSW	10	86,741,403 (GRCm39)	missense	possibly damaging	0.69
R8024:Stab2	UTSW	10	86,681,916 (GRCm39)	missense	probably benign	0.34
R8097:Stab2	UTSW	10	86,704,959 (GRCm39)	missense	possibly damaging	0.86
R8281:Stab2	UTSW	10	86,709,728 (GRCm39)	missense	probably damaging	0.98
R8462:Stab2	UTSW	10	86,803,598 (GRCm39)	missense	possibly damaging	0.79
R8670:Stab2	UTSW	10	86,776,587 (GRCm39)	missense	probably damaging	1.00
R8692:Stab2	UTSW	10	86,808,794 (GRCm39)	missense	probably damaging	0.99
R8744:Stab2	UTSW	10	86,805,213 (GRCm39)	missense	probably benign	0.32
R8745:Stab2	UTSW	10	86,805,213 (GRCm39)	missense	probably benign	0.32
R8782:Stab2	UTSW	10	86,735,685 (GRCm39)	missense	probably benign	0.00
R8875:Stab2	UTSW	10	86,832,728 (GRCm39)	missense	probably damaging	1.00
R8978:Stab2	UTSW	10	86,785,782 (GRCm39)	missense	possibly damaging	0.64
R9141:Stab2	UTSW	10	86,704,911 (GRCm39)	missense	probably damaging	1.00
R9248:Stab2	UTSW	10	86,727,481 (GRCm39)	missense	probably damaging	0.98
R9326:Stab2	UTSW	10	86,791,010 (GRCm39)	missense	probably damaging	1.00
R9426:Stab2	UTSW	10	86,704,911 (GRCm39)	missense	probably damaging	1.00
R9568:Stab2	UTSW	10	86,699,420 (GRCm39)	missense	probably damaging	1.00
R9627:Stab2	UTSW	10	86,793,704 (GRCm39)	missense	probably damaging	0.98
R9635:Stab2	UTSW	10	86,686,651 (GRCm39)	nonsense	probably null
R9648:Stab2	UTSW	10	86,692,561 (GRCm39)	frame shift	probably null
R9649:Stab2	UTSW	10	86,692,561 (GRCm39)	frame shift	probably null
R9650:Stab2	UTSW	10	86,692,561 (GRCm39)	frame shift	probably null
R9726:Stab2	UTSW	10	86,790,095 (GRCm39)	missense	probably benign	0.00
R9756:Stab2	UTSW	10	86,803,553 (GRCm39)	missense	possibly damaging	0.50
R9786:Stab2	UTSW	10	86,757,997 (GRCm39)	missense	probably benign	0.03
RF061:Stab2	UTSW	10	86,702,622 (GRCm39)	critical splice acceptor site	probably benign
X0023:Stab2	UTSW	10	86,758,062 (GRCm39)	critical splice acceptor site	probably null
X0025:Stab2	UTSW	10	86,723,680 (GRCm39)	missense	probably damaging	1.00
Z1176:Stab2	UTSW	10	86,785,778 (GRCm39)	missense	probably damaging	0.99
Z1177:Stab2	UTSW	10	86,732,460 (GRCm39)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- GGGCAGAGTTCAATTTCAAACGCAG -3'
(R):5'- TAATGACCCACAACCAAGGGGCTG -3'

Sequencing Primer
(F):5'- tcaatttcaaacgcagatgtttc -3'
(R):5'- tgtgtgtgtgtgttactaggg -3'

Posted On

2014-04-13