Incidental Mutation 'R1628:Pcnx3'
| ID |
172648 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Pcnx3
|
| Ensembl Gene |
ENSMUSG00000054874 |
| Gene Name |
pecanex homolog 3 |
| Synonyms |
Pcnxl3 |
| MMRRC Submission |
039665-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R1628 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
19 |
| Chromosomal Location |
5714663-5738936 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to T
at 5736093 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Arginine
at position 244
(S244R)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000109245
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000004156]
[ENSMUST00000068169]
[ENSMUST00000113615]
[ENSMUST00000141577]
|
| AlphaFold |
Q8VI59 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000004156
|
| SMART Domains |
Protein: ENSMUSP00000004156
Gene: ENSMUSG00000004054
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
11 |
36 |
N/A |
INTRINSIC |
|
SH3
|
45 |
105 |
6.79e-19 |
SMART |
|
TyrKc
|
118 |
377 |
6.83e-81 |
SMART |
|
coiled coil region
|
398 |
444 |
N/A |
INTRINSIC |
|
low complexity region
|
467 |
476 |
N/A |
INTRINSIC |
|
low complexity region
|
593 |
610 |
N/A |
INTRINSIC |
|
low complexity region
|
614 |
632 |
N/A |
INTRINSIC |
|
low complexity region
|
676 |
697 |
N/A |
INTRINSIC |
|
low complexity region
|
759 |
778 |
N/A |
INTRINSIC |
|
low complexity region
|
786 |
805 |
N/A |
INTRINSIC |
|
low complexity region
|
809 |
820 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000068169
|
| SMART Domains |
Protein: ENSMUSP00000063786
Gene: ENSMUSG00000054874
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
36 |
53 |
N/A |
INTRINSIC |
|
transmembrane domain
|
57 |
79 |
N/A |
INTRINSIC |
|
low complexity region
|
99 |
111 |
N/A |
INTRINSIC |
|
low complexity region
|
370 |
376 |
N/A |
INTRINSIC |
|
transmembrane domain
|
385 |
407 |
N/A |
INTRINSIC |
|
transmembrane domain
|
411 |
428 |
N/A |
INTRINSIC |
|
transmembrane domain
|
441 |
463 |
N/A |
INTRINSIC |
|
transmembrane domain
|
473 |
492 |
N/A |
INTRINSIC |
|
transmembrane domain
|
501 |
523 |
N/A |
INTRINSIC |
|
transmembrane domain
|
538 |
560 |
N/A |
INTRINSIC |
|
transmembrane domain
|
573 |
592 |
N/A |
INTRINSIC |
|
transmembrane domain
|
645 |
667 |
N/A |
INTRINSIC |
|
transmembrane domain
|
669 |
691 |
N/A |
INTRINSIC |
|
low complexity region
|
1011 |
1025 |
N/A |
INTRINSIC |
|
Pfam:Pecanex_C
|
1159 |
1389 |
7.5e-124 |
PFAM |
|
low complexity region
|
1462 |
1479 |
N/A |
INTRINSIC |
|
low complexity region
|
1481 |
1510 |
N/A |
INTRINSIC |
|
low complexity region
|
1525 |
1538 |
N/A |
INTRINSIC |
|
low complexity region
|
1558 |
1569 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000113615
AA Change: S244R
PolyPhen 2
Score 0.992 (Sensitivity: 0.70; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000109245
Gene: ENSMUSG00000054874
AA Change: S244R
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
36 |
53 |
N/A |
INTRINSIC |
|
transmembrane domain
|
57 |
79 |
N/A |
INTRINSIC |
|
low complexity region
|
99 |
111 |
N/A |
INTRINSIC |
|
low complexity region
|
438 |
459 |
N/A |
INTRINSIC |
|
low complexity region
|
778 |
784 |
N/A |
INTRINSIC |
|
transmembrane domain
|
793 |
815 |
N/A |
INTRINSIC |
|
transmembrane domain
|
819 |
836 |
N/A |
INTRINSIC |
|
transmembrane domain
|
849 |
871 |
N/A |
INTRINSIC |
|
transmembrane domain
|
881 |
900 |
N/A |
INTRINSIC |
|
transmembrane domain
|
909 |
931 |
N/A |
INTRINSIC |
|
transmembrane domain
|
946 |
968 |
N/A |
INTRINSIC |
|
transmembrane domain
|
981 |
1000 |
N/A |
INTRINSIC |
|
transmembrane domain
|
1053 |
1075 |
N/A |
INTRINSIC |
|
transmembrane domain
|
1077 |
1099 |
N/A |
INTRINSIC |
|
low complexity region
|
1419 |
1433 |
N/A |
INTRINSIC |
|
Pfam:Pecanex_C
|
1570 |
1796 |
5.9e-116 |
PFAM |
|
low complexity region
|
1870 |
1887 |
N/A |
INTRINSIC |
|
low complexity region
|
1889 |
1918 |
N/A |
INTRINSIC |
|
low complexity region
|
1933 |
1946 |
N/A |
INTRINSIC |
|
low complexity region
|
1966 |
1977 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000127876
|
| SMART Domains |
Protein: ENSMUSP00000123696
Gene: ENSMUSG00000054874
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
69 |
75 |
N/A |
INTRINSIC |
|
transmembrane domain
|
84 |
106 |
N/A |
INTRINSIC |
|
transmembrane domain
|
110 |
127 |
N/A |
INTRINSIC |
|
transmembrane domain
|
140 |
162 |
N/A |
INTRINSIC |
|
transmembrane domain
|
172 |
191 |
N/A |
INTRINSIC |
|
transmembrane domain
|
200 |
222 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000135119
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000141577
|
| SMART Domains |
Protein: ENSMUSP00000116451
Gene: ENSMUSG00000054874
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
104 |
110 |
N/A |
INTRINSIC |
|
transmembrane domain
|
119 |
141 |
N/A |
INTRINSIC |
|
transmembrane domain
|
145 |
162 |
N/A |
INTRINSIC |
|
transmembrane domain
|
175 |
197 |
N/A |
INTRINSIC |
|
transmembrane domain
|
207 |
224 |
N/A |
INTRINSIC |
|
transmembrane domain
|
229 |
251 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000145270
|
| SMART Domains |
Protein: ENSMUSP00000116493
Gene: ENSMUSG00000054874
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
199 |
205 |
N/A |
INTRINSIC |
|
transmembrane domain
|
214 |
236 |
N/A |
INTRINSIC |
|
transmembrane domain
|
240 |
257 |
N/A |
INTRINSIC |
|
transmembrane domain
|
270 |
292 |
N/A |
INTRINSIC |
|
transmembrane domain
|
302 |
321 |
N/A |
INTRINSIC |
|
transmembrane domain
|
330 |
352 |
N/A |
INTRINSIC |
|
transmembrane domain
|
367 |
389 |
N/A |
INTRINSIC |
|
transmembrane domain
|
402 |
421 |
N/A |
INTRINSIC |
|
transmembrane domain
|
474 |
496 |
N/A |
INTRINSIC |
|
transmembrane domain
|
498 |
520 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000147161
|
| Meta Mutation Damage Score |
0.0703 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.3%
- 10x: 96.0%
- 20x: 91.7%
|
| Validation Efficiency |
99% (75/76) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 70 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abcg8 |
C |
T |
17: 84,999,419 (GRCm39) |
Q172* |
probably null |
Het |
| AI467606 |
G |
A |
7: 126,691,755 (GRCm39) |
G110D |
probably benign |
Het |
| Arhgef15 |
A |
C |
11: 68,835,640 (GRCm39) |
L805R |
possibly damaging |
Het |
| B3galnt1 |
G |
A |
3: 69,482,961 (GRCm39) |
T100I |
probably damaging |
Het |
| Bod1l |
T |
A |
5: 41,974,325 (GRCm39) |
M2330L |
probably benign |
Het |
| Calcr |
A |
T |
6: 3,700,251 (GRCm39) |
H280Q |
possibly damaging |
Het |
| Camk1d |
T |
C |
2: 5,315,848 (GRCm39) |
D263G |
probably damaging |
Het |
| Cd48 |
T |
A |
1: 171,532,420 (GRCm39) |
I233N |
probably damaging |
Het |
| Cyp3a25 |
A |
T |
5: 145,938,273 (GRCm39) |
Y68* |
probably null |
Het |
| Dapk3 |
C |
A |
10: 81,027,643 (GRCm39) |
T227K |
possibly damaging |
Het |
| Dnajc22 |
A |
G |
15: 98,998,817 (GRCm39) |
M1V |
probably null |
Het |
| Etv5 |
C |
T |
16: 22,220,421 (GRCm39) |
|
probably null |
Het |
| Gabrr1 |
A |
G |
4: 33,152,432 (GRCm39) |
Y124C |
probably damaging |
Het |
| Gba2 |
C |
T |
4: 43,570,118 (GRCm39) |
R392Q |
probably benign |
Het |
| Gli3 |
C |
G |
13: 15,900,897 (GRCm39) |
A1428G |
probably benign |
Het |
| Gls |
G |
A |
1: 52,271,835 (GRCm39) |
A106V |
probably benign |
Het |
| Gm21370 |
A |
G |
13: 120,488,414 (GRCm39) |
V45A |
possibly damaging |
Het |
| Gpr4 |
A |
G |
7: 18,957,124 (GRCm39) |
T349A |
probably benign |
Het |
| Gpr6 |
C |
T |
10: 40,947,544 (GRCm39) |
V13M |
possibly damaging |
Het |
| Gvin3 |
A |
T |
7: 106,202,476 (GRCm39) |
L256* |
probably null |
Het |
| Hectd3 |
A |
G |
4: 116,854,589 (GRCm39) |
H345R |
probably damaging |
Het |
| Igfl3 |
A |
T |
7: 17,914,232 (GRCm39) |
K135N |
probably benign |
Het |
| Il23r |
A |
G |
6: 67,400,593 (GRCm39) |
L579S |
probably damaging |
Het |
| Itsn2 |
A |
C |
12: 4,679,652 (GRCm39) |
M154L |
probably benign |
Het |
| Junb |
T |
A |
8: 85,705,039 (GRCm39) |
Q7L |
possibly damaging |
Het |
| Kif21b |
T |
A |
1: 136,098,958 (GRCm39) |
H1415Q |
probably benign |
Het |
| Kirrel1 |
C |
T |
3: 86,996,458 (GRCm39) |
M380I |
probably null |
Het |
| Klhdc10 |
T |
G |
6: 30,444,461 (GRCm39) |
F79L |
probably damaging |
Het |
| Klk1b8 |
A |
G |
7: 43,603,565 (GRCm39) |
|
probably null |
Het |
| Lmbrd2 |
T |
A |
15: 9,182,593 (GRCm39) |
N509K |
probably damaging |
Het |
| Mctp2 |
A |
G |
7: 71,861,337 (GRCm39) |
|
probably null |
Het |
| Myo3b |
A |
G |
2: 70,117,306 (GRCm39) |
N913S |
probably benign |
Het |
| N4bp2 |
G |
A |
5: 65,960,915 (GRCm39) |
|
probably null |
Het |
| Nt5c1a |
A |
G |
4: 123,102,284 (GRCm39) |
E70G |
possibly damaging |
Het |
| Or12k5 |
A |
G |
2: 36,894,738 (GRCm39) |
V296A |
probably damaging |
Het |
| Papln |
A |
G |
12: 83,831,180 (GRCm39) |
|
probably benign |
Het |
| Pecam1 |
A |
T |
11: 106,573,786 (GRCm39) |
|
probably null |
Het |
| Plppr4 |
A |
T |
3: 117,121,921 (GRCm39) |
L219Q |
probably damaging |
Het |
| Ppp2r5b |
A |
G |
19: 6,280,935 (GRCm39) |
|
probably null |
Het |
| Ralgapb |
A |
G |
2: 158,272,383 (GRCm39) |
R146G |
probably benign |
Het |
| Rapgef6 |
TG |
TGG |
11: 54,437,223 (GRCm39) |
|
probably null |
Het |
| Rfpl4b |
T |
G |
10: 38,697,530 (GRCm39) |
I24L |
probably benign |
Het |
| Serpinb1b |
G |
A |
13: 33,277,637 (GRCm39) |
C290Y |
probably benign |
Het |
| Skic3 |
A |
G |
13: 76,259,910 (GRCm39) |
E70G |
possibly damaging |
Het |
| Slc25a17 |
A |
G |
15: 81,244,925 (GRCm39) |
S3P |
possibly damaging |
Het |
| Slc4a11 |
A |
C |
2: 130,529,047 (GRCm39) |
|
probably null |
Het |
| Spata31e4 |
T |
C |
13: 50,856,324 (GRCm39) |
L654P |
probably benign |
Het |
| Sptb |
A |
G |
12: 76,630,622 (GRCm39) |
Y2231H |
probably damaging |
Het |
| Srgap1 |
T |
G |
10: 121,706,244 (GRCm39) |
M221L |
probably benign |
Het |
| Srgap3 |
A |
G |
6: 112,716,331 (GRCm39) |
L599P |
probably damaging |
Het |
| Svep1 |
C |
T |
4: 58,107,561 (GRCm39) |
V1177M |
probably benign |
Het |
| Tarbp1 |
A |
G |
8: 127,157,599 (GRCm39) |
F1303L |
possibly damaging |
Het |
| Tbxa2r |
T |
C |
10: 81,170,341 (GRCm39) |
S276P |
possibly damaging |
Het |
| Try10 |
A |
T |
6: 41,334,390 (GRCm39) |
D194V |
probably damaging |
Het |
| Ttc39c |
T |
C |
18: 12,867,936 (GRCm39) |
|
probably benign |
Het |
| Ttc8 |
G |
A |
12: 98,948,780 (GRCm39) |
V489M |
probably benign |
Het |
| Unc13b |
G |
T |
4: 43,263,371 (GRCm39) |
R1912L |
probably damaging |
Het |
| Unc45b |
T |
A |
11: 82,820,206 (GRCm39) |
|
probably null |
Het |
| Usp17lb |
T |
C |
7: 104,490,048 (GRCm39) |
Y292C |
probably damaging |
Het |
| Usp34 |
A |
G |
11: 23,438,725 (GRCm39) |
D3429G |
probably damaging |
Het |
| Usp42 |
A |
G |
5: 143,703,122 (GRCm39) |
S500P |
probably damaging |
Het |
| Vmn2r14 |
T |
C |
5: 109,367,838 (GRCm39) |
M385V |
probably benign |
Het |
| Vmn2r60 |
G |
A |
7: 41,785,830 (GRCm39) |
W211* |
probably null |
Het |
| Vwf |
A |
T |
6: 125,624,701 (GRCm39) |
|
probably benign |
Het |
| Wdfy4 |
A |
T |
14: 32,681,918 (GRCm39) |
F3018I |
probably damaging |
Het |
| Wwox |
A |
G |
8: 115,174,973 (GRCm39) |
T102A |
probably benign |
Het |
| Zfp142 |
A |
C |
1: 74,611,047 (GRCm39) |
L813R |
possibly damaging |
Het |
| Zfp407 |
G |
A |
18: 84,372,658 (GRCm39) |
T1670M |
probably damaging |
Het |
| Zfp93 |
A |
G |
7: 23,974,282 (GRCm39) |
E89G |
probably benign |
Het |
| Zwint |
C |
T |
10: 72,492,127 (GRCm39) |
Q18* |
probably null |
Het |
|
| Other mutations in Pcnx3 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01616:Pcnx3
|
APN |
19 |
5,717,287 (GRCm39) |
unclassified |
probably benign |
|
|
IGL01667:Pcnx3
|
APN |
19 |
5,736,658 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL01704:Pcnx3
|
APN |
19 |
5,717,504 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01752:Pcnx3
|
APN |
19 |
5,715,365 (GRCm39) |
nonsense |
probably null |
|
|
IGL01791:Pcnx3
|
APN |
19 |
5,723,295 (GRCm39) |
missense |
probably benign |
0.39 |
|
IGL01937:Pcnx3
|
APN |
19 |
5,727,691 (GRCm39) |
missense |
probably benign |
|
|
IGL01987:Pcnx3
|
APN |
19 |
5,727,507 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02073:Pcnx3
|
APN |
19 |
5,729,414 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02417:Pcnx3
|
APN |
19 |
5,736,509 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL03143:Pcnx3
|
APN |
19 |
5,735,423 (GRCm39) |
missense |
probably damaging |
1.00 |
|
buns
|
UTSW |
19 |
5,733,368 (GRCm39) |
start codon destroyed |
probably null |
|
|
Pastries
|
UTSW |
19 |
5,733,367 (GRCm39) |
nonsense |
probably null |
|
|
pie
|
UTSW |
19 |
5,717,186 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R7096_pcnx3_526
|
UTSW |
19 |
5,722,643 (GRCm39) |
missense |
probably damaging |
1.00 |
|
swirls
|
UTSW |
19 |
5,722,543 (GRCm39) |
missense |
probably damaging |
1.00 |
|
tip
|
UTSW |
19 |
5,733,808 (GRCm39) |
splice site |
probably benign |
|
|
PIT4453001:Pcnx3
|
UTSW |
19 |
5,722,784 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0234:Pcnx3
|
UTSW |
19 |
5,722,646 (GRCm39) |
missense |
probably benign |
0.12 |
|
R0234:Pcnx3
|
UTSW |
19 |
5,722,646 (GRCm39) |
missense |
probably benign |
0.12 |
|
R0360:Pcnx3
|
UTSW |
19 |
5,715,611 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0687:Pcnx3
|
UTSW |
19 |
5,734,361 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0718:Pcnx3
|
UTSW |
19 |
5,727,756 (GRCm39) |
splice site |
probably benign |
|
|
R0840:Pcnx3
|
UTSW |
19 |
5,735,729 (GRCm39) |
splice site |
probably null |
|
|
R0907:Pcnx3
|
UTSW |
19 |
5,721,553 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1251:Pcnx3
|
UTSW |
19 |
5,727,210 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1373:Pcnx3
|
UTSW |
19 |
5,715,544 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1467:Pcnx3
|
UTSW |
19 |
5,724,922 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R1467:Pcnx3
|
UTSW |
19 |
5,724,922 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R1572:Pcnx3
|
UTSW |
19 |
5,735,375 (GRCm39) |
nonsense |
probably null |
|
|
R1602:Pcnx3
|
UTSW |
19 |
5,722,543 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1635:Pcnx3
|
UTSW |
19 |
5,715,773 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1670:Pcnx3
|
UTSW |
19 |
5,723,343 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1889:Pcnx3
|
UTSW |
19 |
5,722,684 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1898:Pcnx3
|
UTSW |
19 |
5,722,615 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2113:Pcnx3
|
UTSW |
19 |
5,721,584 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R2147:Pcnx3
|
UTSW |
19 |
5,717,633 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2358:Pcnx3
|
UTSW |
19 |
5,733,368 (GRCm39) |
start codon destroyed |
probably null |
|
|
R2358:Pcnx3
|
UTSW |
19 |
5,733,367 (GRCm39) |
nonsense |
probably null |
|
|
R2871:Pcnx3
|
UTSW |
19 |
5,733,774 (GRCm39) |
intron |
probably benign |
|
|
R3699:Pcnx3
|
UTSW |
19 |
5,722,493 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3712:Pcnx3
|
UTSW |
19 |
5,733,368 (GRCm39) |
start codon destroyed |
probably null |
|
|
R3712:Pcnx3
|
UTSW |
19 |
5,733,367 (GRCm39) |
nonsense |
probably null |
|
|
R3798:Pcnx3
|
UTSW |
19 |
5,728,696 (GRCm39) |
nonsense |
probably null |
|
|
R3856:Pcnx3
|
UTSW |
19 |
5,728,995 (GRCm39) |
missense |
probably benign |
0.02 |
|
R3953:Pcnx3
|
UTSW |
19 |
5,733,808 (GRCm39) |
splice site |
probably benign |
|
|
R4613:Pcnx3
|
UTSW |
19 |
5,717,247 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R4781:Pcnx3
|
UTSW |
19 |
5,737,158 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4816:Pcnx3
|
UTSW |
19 |
5,738,023 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5338:Pcnx3
|
UTSW |
19 |
5,722,624 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5770:Pcnx3
|
UTSW |
19 |
5,731,607 (GRCm39) |
intron |
probably benign |
|
|
R5950:Pcnx3
|
UTSW |
19 |
5,717,186 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R5951:Pcnx3
|
UTSW |
19 |
5,721,708 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R5969:Pcnx3
|
UTSW |
19 |
5,735,563 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6543:Pcnx3
|
UTSW |
19 |
5,715,275 (GRCm39) |
missense |
probably benign |
0.07 |
|
R6704:Pcnx3
|
UTSW |
19 |
5,736,515 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R7096:Pcnx3
|
UTSW |
19 |
5,722,643 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7177:Pcnx3
|
UTSW |
19 |
5,737,527 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7308:Pcnx3
|
UTSW |
19 |
5,736,175 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R7387:Pcnx3
|
UTSW |
19 |
5,723,364 (GRCm39) |
missense |
probably benign |
0.33 |
|
R7488:Pcnx3
|
UTSW |
19 |
5,717,487 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R7670:Pcnx3
|
UTSW |
19 |
5,727,210 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7831:Pcnx3
|
UTSW |
19 |
5,735,989 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7850:Pcnx3
|
UTSW |
19 |
5,728,960 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R8120:Pcnx3
|
UTSW |
19 |
5,717,574 (GRCm39) |
missense |
probably benign |
|
|
R8139:Pcnx3
|
UTSW |
19 |
5,715,773 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8258:Pcnx3
|
UTSW |
19 |
5,715,412 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8259:Pcnx3
|
UTSW |
19 |
5,715,412 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8260:Pcnx3
|
UTSW |
19 |
5,715,412 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8261:Pcnx3
|
UTSW |
19 |
5,715,412 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8262:Pcnx3
|
UTSW |
19 |
5,715,412 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8350:Pcnx3
|
UTSW |
19 |
5,723,254 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8411:Pcnx3
|
UTSW |
19 |
5,729,618 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R8429:Pcnx3
|
UTSW |
19 |
5,715,412 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8431:Pcnx3
|
UTSW |
19 |
5,715,412 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8443:Pcnx3
|
UTSW |
19 |
5,736,670 (GRCm39) |
missense |
probably benign |
|
|
R8450:Pcnx3
|
UTSW |
19 |
5,723,254 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8494:Pcnx3
|
UTSW |
19 |
5,725,404 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8790:Pcnx3
|
UTSW |
19 |
5,735,206 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R8939:Pcnx3
|
UTSW |
19 |
5,730,347 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9065:Pcnx3
|
UTSW |
19 |
5,717,582 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R9070:Pcnx3
|
UTSW |
19 |
5,715,601 (GRCm39) |
missense |
probably benign |
0.33 |
|
X0028:Pcnx3
|
UTSW |
19 |
5,734,455 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0053:Pcnx3
|
UTSW |
19 |
5,736,650 (GRCm39) |
splice site |
probably null |
|
|
Z1176:Pcnx3
|
UTSW |
19 |
5,737,248 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
Z1177:Pcnx3
|
UTSW |
19 |
5,721,654 (GRCm39) |
missense |
probably benign |
0.17 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGCCACTGAAGCAGGAATCCGAAG -3'
(R):5'- ACATCATCCCAAAGTTGGCTCCG -3'
Sequencing Primer
(F):5'- ATCCGAAGAGCCAGCTTTCTG -3'
(R):5'- TCCTGGATGGAGCACCTTG -3'
|
| Posted On |
2014-04-24 |
Incidental Mutation