Incidental Mutation 'R1635:Anapc1'
| ID |
173036 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Anapc1
|
| Ensembl Gene |
ENSMUSG00000014355 |
| Gene Name |
anaphase promoting complex subunit 1 |
| Synonyms |
Apc1, tsg24, Mcpr, 2610021O03Rik |
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R1635 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
2 |
| Chromosomal Location |
128452024-128529311 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to T
at 128470452 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Histidine to Glutamine
at position 1559
(H1559Q)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000014499
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000014499]
|
| AlphaFold |
P53995 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000014499
AA Change: H1559Q
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000014499
Gene: ENSMUSG00000014355
AA Change: H1559Q
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:ANAPC1
|
150 |
214 |
1.7e-13 |
PFAM |
|
low complexity region
|
323 |
345 |
N/A |
INTRINSIC |
|
low complexity region
|
1404 |
1415 |
N/A |
INTRINSIC |
|
Pfam:PC_rep
|
1467 |
1501 |
8.3e-8 |
PFAM |
|
low complexity region
|
1516 |
1528 |
N/A |
INTRINSIC |
|
low complexity region
|
1924 |
1936 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000145906
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000154320
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000154995
|
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.3%
- 10x: 96.0%
- 20x: 91.9%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a subunit of the anaphase-promoting complex. This complex is an E3 ubiquitin ligase that regulates progression through the metaphase to anaphase portion of the cell cycle by ubiquitinating proteins which targets them for degradation. [provided by RefSeq, Dec 2011]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 95 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca2 |
A |
T |
2: 25,334,868 (GRCm39) |
I1947F |
probably benign |
Het |
| Adgrd1 |
G |
T |
5: 129,205,971 (GRCm39) |
V182F |
probably damaging |
Het |
| Agmat |
A |
G |
4: 141,474,380 (GRCm39) |
D87G |
probably damaging |
Het |
| AI182371 |
T |
C |
2: 34,978,749 (GRCm39) |
|
probably null |
Het |
| Ankar |
T |
C |
1: 72,689,297 (GRCm39) |
Y1278C |
probably damaging |
Het |
| Arhgef2 |
A |
T |
3: 88,546,628 (GRCm39) |
|
probably null |
Het |
| Arsi |
G |
A |
18: 61,049,723 (GRCm39) |
G202E |
probably benign |
Het |
| Banp |
A |
T |
8: 122,727,750 (GRCm39) |
I130F |
probably damaging |
Het |
| C130050O18Rik |
G |
T |
5: 139,400,248 (GRCm39) |
R100S |
probably benign |
Het |
| Carmil3 |
A |
G |
14: 55,733,739 (GRCm39) |
T374A |
possibly damaging |
Het |
| Cc2d2a |
T |
A |
5: 43,879,812 (GRCm39) |
W1076R |
probably damaging |
Het |
| Cdc34 |
T |
G |
10: 79,523,888 (GRCm39) |
S235A |
probably benign |
Het |
| Cdh8 |
G |
T |
8: 99,757,656 (GRCm39) |
H647Q |
probably damaging |
Het |
| Cdk1 |
A |
T |
10: 69,174,377 (GRCm39) |
L282Q |
probably damaging |
Het |
| Ceacam3 |
A |
G |
7: 16,893,902 (GRCm39) |
D471G |
probably damaging |
Het |
| Ciao2b |
A |
T |
8: 105,367,620 (GRCm39) |
I108N |
possibly damaging |
Het |
| Cltc |
A |
T |
11: 86,648,105 (GRCm39) |
I4N |
probably benign |
Het |
| Cntfr |
T |
A |
4: 41,658,816 (GRCm39) |
E305V |
probably damaging |
Het |
| Cwh43 |
T |
A |
5: 73,591,653 (GRCm39) |
I496N |
probably damaging |
Het |
| Cyp2f2 |
A |
G |
7: 26,829,149 (GRCm39) |
N218S |
probably benign |
Het |
| D16Ertd472e |
A |
G |
16: 78,343,392 (GRCm39) |
|
probably null |
Het |
| Dab2 |
A |
G |
15: 6,459,351 (GRCm39) |
Q400R |
possibly damaging |
Het |
| Dapl1 |
A |
T |
2: 59,326,906 (GRCm39) |
I51F |
probably benign |
Het |
| Drc7 |
G |
A |
8: 95,800,960 (GRCm39) |
|
probably null |
Het |
| Etl4 |
A |
G |
2: 20,811,219 (GRCm39) |
T1101A |
probably damaging |
Het |
| Fam83c |
C |
A |
2: 155,671,971 (GRCm39) |
R488M |
possibly damaging |
Het |
| Fbxo42 |
A |
G |
4: 140,927,840 (GRCm39) |
T707A |
probably damaging |
Het |
| Fcmr |
A |
T |
1: 130,803,922 (GRCm39) |
|
probably null |
Het |
| Fer1l6 |
G |
C |
15: 58,518,930 (GRCm39) |
K1687N |
probably damaging |
Het |
| Fgd4 |
G |
A |
16: 16,292,893 (GRCm39) |
R275* |
probably null |
Het |
| Fxr2 |
G |
A |
11: 69,532,139 (GRCm39) |
C87Y |
possibly damaging |
Het |
| Gja4 |
A |
T |
4: 127,206,472 (GRCm39) |
I97N |
probably damaging |
Het |
| Gm136 |
A |
G |
4: 34,750,919 (GRCm39) |
|
probably null |
Het |
| Gm14496 |
A |
G |
2: 181,642,837 (GRCm39) |
D836G |
possibly damaging |
Het |
| Grm3 |
T |
A |
5: 9,561,520 (GRCm39) |
T777S |
probably damaging |
Het |
| Guca2b |
A |
G |
4: 119,514,912 (GRCm39) |
Y50H |
probably damaging |
Het |
| Herc2 |
C |
T |
7: 55,786,415 (GRCm39) |
P1587S |
probably benign |
Het |
| Hmcn1 |
C |
T |
1: 150,545,309 (GRCm39) |
S2766N |
probably benign |
Het |
| Idi2 |
T |
A |
13: 9,009,455 (GRCm39) |
I224K |
probably damaging |
Het |
| Kmt2a |
A |
T |
9: 44,735,666 (GRCm39) |
|
probably benign |
Het |
| Lonp2 |
A |
T |
8: 87,440,078 (GRCm39) |
M693L |
possibly damaging |
Het |
| Megf8 |
G |
T |
7: 25,046,172 (GRCm39) |
M1525I |
possibly damaging |
Het |
| Mgme1 |
T |
C |
2: 144,121,018 (GRCm39) |
V276A |
possibly damaging |
Het |
| Mief2 |
G |
T |
11: 60,622,234 (GRCm39) |
W268L |
probably damaging |
Het |
| Mpped1 |
C |
T |
15: 83,676,191 (GRCm39) |
|
probably benign |
Het |
| Mreg |
T |
C |
1: 72,231,356 (GRCm39) |
N34S |
probably benign |
Het |
| Myf6 |
T |
C |
10: 107,330,534 (GRCm39) |
Y11C |
probably damaging |
Het |
| Myh9 |
C |
A |
15: 77,655,367 (GRCm39) |
Q1196H |
probably benign |
Het |
| Myh9 |
A |
T |
15: 77,660,099 (GRCm39) |
D56E |
probably benign |
Het |
| Myo5c |
A |
T |
9: 75,184,357 (GRCm39) |
R949S |
probably benign |
Het |
| Ncapg2 |
TAA |
TA |
12: 116,398,305 (GRCm39) |
|
probably null |
Het |
| Nfx1 |
T |
A |
4: 40,977,004 (GRCm39) |
V226E |
probably benign |
Het |
| Nlrp10 |
T |
A |
7: 108,523,737 (GRCm39) |
K581M |
possibly damaging |
Het |
| Nmd3 |
T |
G |
3: 69,647,317 (GRCm39) |
I273S |
probably benign |
Het |
| Or4c3 |
A |
T |
2: 89,852,314 (GRCm39) |
I32N |
possibly damaging |
Het |
| P4hb |
T |
C |
11: 120,462,442 (GRCm39) |
E88G |
probably damaging |
Het |
| Pcnx3 |
A |
T |
19: 5,715,773 (GRCm39) |
H1444Q |
probably benign |
Het |
| Pdia4 |
A |
T |
6: 47,776,133 (GRCm39) |
F421L |
possibly damaging |
Het |
| Picalm |
T |
A |
7: 89,840,459 (GRCm39) |
S538T |
probably damaging |
Het |
| Ppp2r2b |
T |
A |
18: 43,192,275 (GRCm39) |
I11F |
probably benign |
Het |
| Prb1c |
A |
G |
6: 132,339,969 (GRCm39) |
|
probably null |
Het |
| Ptk7 |
C |
T |
17: 46,884,460 (GRCm39) |
E757K |
possibly damaging |
Het |
| Rbm22 |
T |
G |
18: 60,694,340 (GRCm39) |
C24W |
probably damaging |
Het |
| Rev3l |
A |
G |
10: 39,682,658 (GRCm39) |
D288G |
probably damaging |
Het |
| Rgs18 |
T |
A |
1: 144,629,791 (GRCm39) |
H156L |
probably benign |
Het |
| Rnf213 |
A |
G |
11: 119,333,405 (GRCm39) |
I2871M |
probably damaging |
Het |
| Rrm2b |
A |
T |
15: 37,945,328 (GRCm39) |
M137K |
probably damaging |
Het |
| Rrp12 |
A |
T |
19: 41,857,224 (GRCm39) |
D1183E |
probably benign |
Het |
| Sacs |
G |
A |
14: 61,441,277 (GRCm39) |
V1108M |
probably damaging |
Het |
| Scube2 |
A |
T |
7: 109,442,421 (GRCm39) |
D270E |
possibly damaging |
Het |
| Serpina3a |
T |
A |
12: 104,082,737 (GRCm39) |
F170Y |
probably damaging |
Het |
| Serpinb3b |
T |
C |
1: 107,082,403 (GRCm39) |
E287G |
probably benign |
Het |
| Slamf8 |
C |
T |
1: 172,412,186 (GRCm39) |
V130M |
probably damaging |
Het |
| Slc5a3 |
T |
C |
16: 91,874,284 (GRCm39) |
S114P |
possibly damaging |
Het |
| Sos1 |
T |
A |
17: 80,730,108 (GRCm39) |
|
probably null |
Het |
| Sox10 |
A |
T |
15: 79,040,660 (GRCm39) |
D293E |
probably damaging |
Het |
| Sphk1 |
A |
G |
11: 116,426,596 (GRCm39) |
D177G |
probably damaging |
Het |
| Sphkap |
T |
G |
1: 83,256,121 (GRCm39) |
M543L |
probably benign |
Het |
| Syt13 |
A |
T |
2: 92,783,760 (GRCm39) |
K343N |
probably damaging |
Het |
| Tatdn3 |
A |
G |
1: 190,792,373 (GRCm39) |
M34T |
probably benign |
Het |
| Timd4 |
T |
G |
11: 46,732,989 (GRCm39) |
V305G |
possibly damaging |
Het |
| Tnnc2 |
T |
C |
2: 164,619,512 (GRCm39) |
I111V |
probably benign |
Het |
| Togaram2 |
C |
T |
17: 72,004,846 (GRCm39) |
P301L |
probably benign |
Het |
| Trpc3 |
T |
C |
3: 36,694,776 (GRCm39) |
N726S |
probably damaging |
Het |
| Tspear |
T |
A |
10: 77,706,253 (GRCm39) |
L341H |
possibly damaging |
Het |
| Ugt1a5 |
T |
A |
1: 88,093,805 (GRCm39) |
|
probably benign |
Het |
| Ulk3 |
A |
T |
9: 57,500,443 (GRCm39) |
|
probably null |
Het |
| Unc5d |
T |
A |
8: 29,250,777 (GRCm39) |
I297L |
probably benign |
Het |
| Usp20 |
A |
G |
2: 30,908,830 (GRCm39) |
I804V |
probably benign |
Het |
| Usp22 |
G |
T |
11: 61,052,144 (GRCm39) |
C278* |
probably null |
Het |
| Usp53 |
A |
T |
3: 122,727,872 (GRCm39) |
N903K |
probably benign |
Het |
| V1rd19 |
T |
C |
7: 23,702,812 (GRCm39) |
F93L |
probably benign |
Het |
| Zdbf2 |
T |
A |
1: 63,343,493 (GRCm39) |
V624E |
possibly damaging |
Het |
| Zfyve16 |
A |
T |
13: 92,645,528 (GRCm39) |
S1073T |
probably damaging |
Het |
| Zkscan8 |
T |
C |
13: 21,710,765 (GRCm39) |
H115R |
possibly damaging |
Het |
|
| Other mutations in Anapc1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00232:Anapc1
|
APN |
2 |
128,487,050 (GRCm39) |
splice site |
probably benign |
|
|
IGL00704:Anapc1
|
APN |
2 |
128,505,904 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
IGL01023:Anapc1
|
APN |
2 |
128,471,649 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01432:Anapc1
|
APN |
2 |
128,475,328 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01549:Anapc1
|
APN |
2 |
128,495,090 (GRCm39) |
missense |
probably benign |
|
|
IGL02089:Anapc1
|
APN |
2 |
128,505,853 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02275:Anapc1
|
APN |
2 |
128,501,772 (GRCm39) |
missense |
probably benign |
|
|
IGL02570:Anapc1
|
APN |
2 |
128,487,120 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02597:Anapc1
|
APN |
2 |
128,465,851 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL02726:Anapc1
|
APN |
2 |
128,501,705 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL03265:Anapc1
|
APN |
2 |
128,469,117 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03304:Anapc1
|
APN |
2 |
128,469,033 (GRCm39) |
splice site |
probably benign |
|
|
IGL03327:Anapc1
|
APN |
2 |
128,465,854 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0023:Anapc1
|
UTSW |
2 |
128,520,138 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0027:Anapc1
|
UTSW |
2 |
128,483,431 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R0027:Anapc1
|
UTSW |
2 |
128,483,431 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R0084:Anapc1
|
UTSW |
2 |
128,465,886 (GRCm39) |
splice site |
probably benign |
|
|
R0103:Anapc1
|
UTSW |
2 |
128,522,372 (GRCm39) |
splice site |
probably benign |
|
|
R0103:Anapc1
|
UTSW |
2 |
128,522,372 (GRCm39) |
splice site |
probably benign |
|
|
R0109:Anapc1
|
UTSW |
2 |
128,476,613 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0109:Anapc1
|
UTSW |
2 |
128,476,613 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0241:Anapc1
|
UTSW |
2 |
128,470,549 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R0241:Anapc1
|
UTSW |
2 |
128,470,549 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R0255:Anapc1
|
UTSW |
2 |
128,476,631 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0377:Anapc1
|
UTSW |
2 |
128,483,260 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0467:Anapc1
|
UTSW |
2 |
128,510,963 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0514:Anapc1
|
UTSW |
2 |
128,474,575 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0591:Anapc1
|
UTSW |
2 |
128,461,252 (GRCm39) |
missense |
probably benign |
0.17 |
|
R0919:Anapc1
|
UTSW |
2 |
128,459,651 (GRCm39) |
missense |
probably benign |
|
|
R1175:Anapc1
|
UTSW |
2 |
128,522,108 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1473:Anapc1
|
UTSW |
2 |
128,459,617 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R1547:Anapc1
|
UTSW |
2 |
128,459,476 (GRCm39) |
missense |
probably benign |
0.44 |
|
R1556:Anapc1
|
UTSW |
2 |
128,466,819 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1567:Anapc1
|
UTSW |
2 |
128,459,636 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1645:Anapc1
|
UTSW |
2 |
128,500,166 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1677:Anapc1
|
UTSW |
2 |
128,518,128 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1854:Anapc1
|
UTSW |
2 |
128,517,810 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1856:Anapc1
|
UTSW |
2 |
128,501,708 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1959:Anapc1
|
UTSW |
2 |
128,475,335 (GRCm39) |
missense |
probably benign |
0.36 |
|
R1984:Anapc1
|
UTSW |
2 |
128,511,608 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R2034:Anapc1
|
UTSW |
2 |
128,490,378 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R2283:Anapc1
|
UTSW |
2 |
128,484,468 (GRCm39) |
missense |
probably benign |
0.23 |
|
R2928:Anapc1
|
UTSW |
2 |
128,522,057 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3547:Anapc1
|
UTSW |
2 |
128,484,602 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R3904:Anapc1
|
UTSW |
2 |
128,484,439 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4156:Anapc1
|
UTSW |
2 |
128,469,149 (GRCm39) |
intron |
probably benign |
|
|
R4359:Anapc1
|
UTSW |
2 |
128,465,476 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R4392:Anapc1
|
UTSW |
2 |
128,518,169 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R4574:Anapc1
|
UTSW |
2 |
128,469,115 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4682:Anapc1
|
UTSW |
2 |
128,505,925 (GRCm39) |
missense |
probably benign |
0.05 |
|
R4770:Anapc1
|
UTSW |
2 |
128,527,980 (GRCm39) |
splice site |
probably benign |
|
|
R4824:Anapc1
|
UTSW |
2 |
128,470,610 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R4960:Anapc1
|
UTSW |
2 |
128,526,514 (GRCm39) |
missense |
probably benign |
0.23 |
|
R5016:Anapc1
|
UTSW |
2 |
128,449,095 (GRCm39) |
unclassified |
probably benign |
|
|
R5063:Anapc1
|
UTSW |
2 |
128,471,469 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R5128:Anapc1
|
UTSW |
2 |
128,501,837 (GRCm39) |
missense |
probably benign |
|
|
R5271:Anapc1
|
UTSW |
2 |
128,527,905 (GRCm39) |
nonsense |
probably null |
|
|
R5363:Anapc1
|
UTSW |
2 |
128,492,114 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5469:Anapc1
|
UTSW |
2 |
128,517,621 (GRCm39) |
nonsense |
probably null |
|
|
R5473:Anapc1
|
UTSW |
2 |
128,449,115 (GRCm39) |
unclassified |
probably benign |
|
|
R5559:Anapc1
|
UTSW |
2 |
128,522,354 (GRCm39) |
nonsense |
probably null |
|
|
R5631:Anapc1
|
UTSW |
2 |
128,499,137 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R5747:Anapc1
|
UTSW |
2 |
128,466,836 (GRCm39) |
missense |
probably benign |
0.19 |
|
R5840:Anapc1
|
UTSW |
2 |
128,448,957 (GRCm39) |
unclassified |
probably benign |
|
|
R6226:Anapc1
|
UTSW |
2 |
128,492,292 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6526:Anapc1
|
UTSW |
2 |
128,514,055 (GRCm39) |
nonsense |
probably null |
|
|
R6561:Anapc1
|
UTSW |
2 |
128,505,919 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6743:Anapc1
|
UTSW |
2 |
128,526,454 (GRCm39) |
nonsense |
probably null |
|
|
R6799:Anapc1
|
UTSW |
2 |
128,501,657 (GRCm39) |
missense |
probably null |
0.38 |
|
R6887:Anapc1
|
UTSW |
2 |
128,501,688 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R6978:Anapc1
|
UTSW |
2 |
128,511,820 (GRCm39) |
missense |
probably benign |
0.06 |
|
R7011:Anapc1
|
UTSW |
2 |
128,490,601 (GRCm39) |
splice site |
probably null |
|
|
R7041:Anapc1
|
UTSW |
2 |
128,470,576 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R7047:Anapc1
|
UTSW |
2 |
128,457,350 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7074:Anapc1
|
UTSW |
2 |
128,520,194 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7109:Anapc1
|
UTSW |
2 |
128,516,522 (GRCm39) |
missense |
probably benign |
0.33 |
|
R7123:Anapc1
|
UTSW |
2 |
128,454,930 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7309:Anapc1
|
UTSW |
2 |
128,516,604 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7693:Anapc1
|
UTSW |
2 |
128,483,457 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R7839:Anapc1
|
UTSW |
2 |
128,526,528 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7847:Anapc1
|
UTSW |
2 |
128,511,828 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R7960:Anapc1
|
UTSW |
2 |
128,516,513 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8061:Anapc1
|
UTSW |
2 |
128,490,408 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8127:Anapc1
|
UTSW |
2 |
128,474,547 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8228:Anapc1
|
UTSW |
2 |
128,461,837 (GRCm39) |
nonsense |
probably null |
|
|
R8402:Anapc1
|
UTSW |
2 |
128,472,148 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8422:Anapc1
|
UTSW |
2 |
128,517,757 (GRCm39) |
missense |
probably benign |
|
|
R8425:Anapc1
|
UTSW |
2 |
128,511,788 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8469:Anapc1
|
UTSW |
2 |
128,500,264 (GRCm39) |
splice site |
probably null |
|
|
R8553:Anapc1
|
UTSW |
2 |
128,461,833 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R8688:Anapc1
|
UTSW |
2 |
128,527,748 (GRCm39) |
missense |
probably benign |
0.19 |
|
R8699:Anapc1
|
UTSW |
2 |
128,483,373 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8719:Anapc1
|
UTSW |
2 |
128,483,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8775:Anapc1
|
UTSW |
2 |
128,499,093 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8775-TAIL:Anapc1
|
UTSW |
2 |
128,499,093 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8806:Anapc1
|
UTSW |
2 |
128,464,333 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R8973:Anapc1
|
UTSW |
2 |
128,505,952 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8977:Anapc1
|
UTSW |
2 |
128,483,322 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9000:Anapc1
|
UTSW |
2 |
128,476,628 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9080:Anapc1
|
UTSW |
2 |
128,464,426 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R9203:Anapc1
|
UTSW |
2 |
128,465,422 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R9314:Anapc1
|
UTSW |
2 |
128,464,420 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R9386:Anapc1
|
UTSW |
2 |
128,459,642 (GRCm39) |
missense |
probably benign |
0.08 |
|
R9415:Anapc1
|
UTSW |
2 |
128,476,598 (GRCm39) |
missense |
probably benign |
|
|
R9436:Anapc1
|
UTSW |
2 |
128,518,045 (GRCm39) |
missense |
probably benign |
|
|
R9516:Anapc1
|
UTSW |
2 |
128,517,633 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R9563:Anapc1
|
UTSW |
2 |
128,505,980 (GRCm39) |
nonsense |
probably null |
|
|
R9572:Anapc1
|
UTSW |
2 |
128,505,976 (GRCm39) |
missense |
probably benign |
|
|
R9757:Anapc1
|
UTSW |
2 |
128,517,676 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9766:Anapc1
|
UTSW |
2 |
128,500,221 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0066:Anapc1
|
UTSW |
2 |
128,516,621 (GRCm39) |
missense |
probably benign |
0.10 |
|
| Predicted Primers |
PCR Primer
(F):5'- CAAGGGACTTCAATCCTCTGCTGC -3'
(R):5'- AACCTCGAAACCTGCCTGAGTGTG -3'
Sequencing Primer
(F):5'- GCAGGTGCCATCAATACAGTTC -3'
(R):5'- CCTGAGTGTGGTCCTGC -3'
|
| Posted On |
2014-04-24 |
Incidental Mutation