Incidental Mutation 'R1638:Pik3r4'
| ID |
173315 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Pik3r4
|
| Ensembl Gene |
ENSMUSG00000032571 |
| Gene Name |
phosphoinositide-3-kinase regulatory subunit 4 |
| Synonyms |
p150, Vps15 |
| MMRRC Submission |
039674-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R1638 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
9 |
| Chromosomal Location |
105520177-105564856 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 105564408 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Glycine
at position 1334
(D1334G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000139427
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000065778]
[ENSMUST00000098441]
[ENSMUST00000166431]
[ENSMUST00000191268]
|
| AlphaFold |
Q8VD65 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000065778
AA Change: D1334G
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000067400
Gene: ENSMUSG00000032571
AA Change: D1334G
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Pkinase_Tyr
|
26 |
310 |
1.7e-5 |
PFAM |
|
Pfam:Pkinase
|
26 |
312 |
1.2e-18 |
PFAM |
|
coiled coil region
|
941 |
963 |
N/A |
INTRINSIC |
|
WD40
|
982 |
1021 |
3.99e-8 |
SMART |
|
WD40
|
1031 |
1070 |
6.16e0 |
SMART |
|
WD40
|
1132 |
1169 |
4.58e1 |
SMART |
|
WD40
|
1171 |
1214 |
1.64e2 |
SMART |
|
WD40
|
1228 |
1269 |
2.76e-2 |
SMART |
|
WD40
|
1317 |
1358 |
2.96e-2 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000098441
|
| SMART Domains |
Protein: ENSMUSP00000096040
Gene: ENSMUSG00000043719
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
17 |
N/A |
INTRINSIC |
|
VWA
|
24 |
197 |
4.26e-26 |
SMART |
|
VWA
|
226 |
407 |
1.06e-30 |
SMART |
|
VWA
|
433 |
610 |
5.19e-39 |
SMART |
|
VWA
|
619 |
795 |
3.58e-42 |
SMART |
|
VWA
|
806 |
982 |
6.64e-37 |
SMART |
|
VWA
|
997 |
1175 |
2.7e-37 |
SMART |
|
VWA
|
1184 |
1370 |
3.45e-1 |
SMART |
|
Pfam:Collagen
|
1389 |
1450 |
3.3e-9 |
PFAM |
|
low complexity region
|
1451 |
1475 |
N/A |
INTRINSIC |
|
low complexity region
|
1490 |
1508 |
N/A |
INTRINSIC |
|
low complexity region
|
1602 |
1623 |
N/A |
INTRINSIC |
|
low complexity region
|
1698 |
1724 |
N/A |
INTRINSIC |
|
VWA
|
1754 |
1937 |
1.73e-17 |
SMART |
|
VWA
|
1962 |
2145 |
4.4e-19 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000166431
|
| SMART Domains |
Protein: ENSMUSP00000125765
Gene: ENSMUSG00000043719
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
17 |
N/A |
INTRINSIC |
|
VWA
|
24 |
197 |
4.26e-26 |
SMART |
|
VWA
|
226 |
407 |
1.06e-30 |
SMART |
|
VWA
|
433 |
610 |
5.19e-39 |
SMART |
|
VWA
|
619 |
795 |
3.58e-42 |
SMART |
|
VWA
|
806 |
982 |
6.64e-37 |
SMART |
|
VWA
|
997 |
1175 |
2.7e-37 |
SMART |
|
VWA
|
1184 |
1370 |
3.45e-1 |
SMART |
|
Pfam:Collagen
|
1389 |
1450 |
9.3e-10 |
PFAM |
|
low complexity region
|
1451 |
1475 |
N/A |
INTRINSIC |
|
low complexity region
|
1490 |
1508 |
N/A |
INTRINSIC |
|
low complexity region
|
1602 |
1623 |
N/A |
INTRINSIC |
|
low complexity region
|
1698 |
1724 |
N/A |
INTRINSIC |
|
VWA
|
1754 |
1937 |
1.73e-17 |
SMART |
|
VWA
|
1962 |
2145 |
4.4e-19 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000189691
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000191268
AA Change: D1334G
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000139427
Gene: ENSMUSG00000032571
AA Change: D1334G
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Pkinase_Tyr
|
26 |
310 |
8.9e-7 |
PFAM |
|
Pfam:Pkinase
|
26 |
312 |
3.7e-23 |
PFAM |
|
coiled coil region
|
941 |
963 |
N/A |
INTRINSIC |
|
WD40
|
982 |
1021 |
3.99e-8 |
SMART |
|
WD40
|
1031 |
1070 |
6.16e0 |
SMART |
|
WD40
|
1132 |
1169 |
4.58e1 |
SMART |
|
WD40
|
1171 |
1214 |
1.64e2 |
SMART |
|
WD40
|
1228 |
1269 |
2.76e-2 |
SMART |
|
WD40
|
1317 |
1358 |
2.96e-2 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000214254
|
| Meta Mutation Damage Score |
0.6437 |
| Coding Region Coverage |
- 1x: 99.0%
- 3x: 97.9%
- 10x: 94.9%
- 20x: 87.8%
|
| Validation Efficiency |
99% (79/80) |
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a knock-out allele exhibit earl embryonic lethality before E7.5. Mice homozygous for a conditional allele activated in muscles exhibit symptoms of autophagic vacuolar myopathies. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 71 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| A2m |
C |
A |
6: 121,631,571 (GRCm39) |
L623M |
probably benign |
Het |
| Adamts13 |
A |
G |
2: 26,886,595 (GRCm39) |
E938G |
possibly damaging |
Het |
| Agfg1 |
A |
T |
1: 82,871,259 (GRCm39) |
Q497L |
probably damaging |
Het |
| Ahnak |
A |
G |
19: 8,986,813 (GRCm39) |
H2699R |
probably benign |
Het |
| Antxrl |
G |
T |
14: 33,792,453 (GRCm39) |
|
probably null |
Het |
| Apol7c |
A |
T |
15: 77,410,418 (GRCm39) |
V176E |
probably damaging |
Het |
| Arid5b |
T |
C |
10: 68,113,777 (GRCm39) |
N87D |
possibly damaging |
Het |
| Atp2c1 |
A |
T |
9: 105,309,897 (GRCm39) |
I560N |
probably damaging |
Het |
| Atp2c2 |
T |
C |
8: 120,482,742 (GRCm39) |
F868S |
possibly damaging |
Het |
| Blnk |
G |
C |
19: 40,926,122 (GRCm39) |
F326L |
probably benign |
Het |
| Bltp1 |
C |
T |
3: 37,089,961 (GRCm39) |
R4130* |
probably null |
Het |
| Ckap2 |
C |
T |
8: 22,665,812 (GRCm39) |
V412I |
possibly damaging |
Het |
| Clmn |
A |
G |
12: 104,748,281 (GRCm39) |
V422A |
probably benign |
Het |
| Ctnnal1 |
A |
G |
4: 56,813,856 (GRCm39) |
S638P |
probably benign |
Het |
| Cyp2j5 |
T |
C |
4: 96,524,052 (GRCm39) |
S327G |
probably benign |
Het |
| Dhx38 |
G |
A |
8: 110,280,177 (GRCm39) |
T871M |
probably damaging |
Het |
| Dmxl1 |
A |
T |
18: 50,023,834 (GRCm39) |
K1706* |
probably null |
Het |
| Dnah11 |
A |
G |
12: 117,979,154 (GRCm39) |
L2648P |
possibly damaging |
Het |
| Elf2 |
G |
A |
3: 51,215,530 (GRCm39) |
T60I |
probably damaging |
Het |
| Fam120b |
T |
A |
17: 15,622,759 (GRCm39) |
C246S |
possibly damaging |
Het |
| Fcho2 |
G |
T |
13: 98,882,403 (GRCm39) |
T451K |
possibly damaging |
Het |
| Fzd9 |
T |
A |
5: 135,278,602 (GRCm39) |
I428F |
probably damaging |
Het |
| Galnt13 |
T |
A |
2: 54,744,667 (GRCm39) |
V122E |
probably damaging |
Het |
| Gm21738 |
T |
A |
14: 19,418,908 (GRCm38) |
Y8F |
probably benign |
Het |
| Gnptab |
A |
G |
10: 88,272,029 (GRCm39) |
I940V |
possibly damaging |
Het |
| Gp2 |
A |
G |
7: 119,050,721 (GRCm39) |
|
probably null |
Het |
| Gpr6 |
A |
G |
10: 40,946,530 (GRCm39) |
S351P |
probably benign |
Het |
| Gprin1 |
T |
C |
13: 54,887,689 (GRCm39) |
E195G |
possibly damaging |
Het |
| Grm8 |
A |
T |
6: 28,125,882 (GRCm39) |
Y81* |
probably null |
Het |
| Gtf3c3 |
A |
T |
1: 54,444,278 (GRCm39) |
N703K |
probably damaging |
Het |
| Hhipl2 |
G |
A |
1: 183,208,921 (GRCm39) |
V495I |
probably benign |
Het |
| Islr |
G |
A |
9: 58,065,502 (GRCm39) |
|
probably benign |
Het |
| Lrrc36 |
T |
C |
8: 106,176,273 (GRCm39) |
Y216H |
possibly damaging |
Het |
| Macroh2a1 |
T |
A |
13: 56,252,722 (GRCm39) |
N87Y |
probably damaging |
Het |
| Me2 |
A |
G |
18: 73,906,205 (GRCm39) |
I528T |
probably benign |
Het |
| Mecr |
A |
T |
4: 131,585,127 (GRCm39) |
I156F |
possibly damaging |
Het |
| Megf6 |
A |
G |
4: 154,346,967 (GRCm39) |
|
probably benign |
Het |
| Mn1 |
T |
A |
5: 111,569,435 (GRCm39) |
L1135H |
probably damaging |
Het |
| Naip5 |
A |
G |
13: 100,349,177 (GRCm39) |
S1384P |
probably damaging |
Het |
| Nav2 |
A |
G |
7: 49,102,213 (GRCm39) |
N337S |
probably benign |
Het |
| Ndn |
C |
T |
7: 61,998,256 (GRCm39) |
P34L |
probably benign |
Het |
| Neb |
A |
T |
2: 52,139,293 (GRCm39) |
H3107Q |
probably benign |
Het |
| Nebl |
A |
G |
2: 17,381,462 (GRCm39) |
V738A |
possibly damaging |
Het |
| Nsd2 |
G |
A |
5: 34,039,464 (GRCm39) |
R825Q |
possibly damaging |
Het |
| Nsun2 |
A |
G |
13: 69,775,705 (GRCm39) |
N383S |
probably damaging |
Het |
| Ntrk3 |
A |
T |
7: 77,897,036 (GRCm39) |
M667K |
probably damaging |
Het |
| Or10a48 |
A |
C |
7: 108,424,442 (GRCm39) |
C255G |
probably benign |
Het |
| Or11h6 |
G |
A |
14: 50,880,565 (GRCm39) |
V276M |
possibly damaging |
Het |
| Or1e29 |
A |
G |
11: 73,667,974 (GRCm39) |
Y60H |
possibly damaging |
Het |
| Or6c2 |
A |
T |
10: 129,362,488 (GRCm39) |
M131L |
probably benign |
Het |
| Pex6 |
T |
C |
17: 47,033,558 (GRCm39) |
V633A |
probably benign |
Het |
| Phactr1 |
C |
T |
13: 43,110,147 (GRCm39) |
T95M |
probably damaging |
Het |
| Pkhd1l1 |
A |
C |
15: 44,460,513 (GRCm39) |
I4241L |
probably benign |
Het |
| Ppwd1 |
T |
C |
13: 104,356,771 (GRCm39) |
E248G |
probably damaging |
Het |
| Prepl |
A |
C |
17: 85,379,509 (GRCm39) |
M393R |
probably benign |
Het |
| Ptpn6 |
T |
C |
6: 124,698,148 (GRCm39) |
S532G |
probably benign |
Het |
| Rnase11 |
G |
T |
14: 51,287,058 (GRCm39) |
H165Q |
possibly damaging |
Het |
| Sf1 |
A |
G |
19: 6,422,090 (GRCm39) |
N172S |
possibly damaging |
Het |
| Shprh |
T |
A |
10: 11,032,822 (GRCm39) |
D269E |
probably benign |
Het |
| Slc16a1 |
T |
C |
3: 104,556,798 (GRCm39) |
I61T |
possibly damaging |
Het |
| Slc38a2 |
A |
C |
15: 96,590,417 (GRCm39) |
I309S |
probably damaging |
Het |
| Sry |
C |
G |
Y: 2,663,149 (GRCm39) |
Q170H |
unknown |
Het |
| Stk3 |
A |
C |
15: 35,008,454 (GRCm39) |
|
probably null |
Het |
| Tg |
C |
A |
15: 66,568,015 (GRCm39) |
C1306* |
probably null |
Het |
| Tnik |
A |
G |
3: 28,719,889 (GRCm39) |
M1254V |
probably damaging |
Het |
| U2surp |
T |
C |
9: 95,366,280 (GRCm39) |
E474G |
possibly damaging |
Het |
| Vmn1r224 |
T |
A |
17: 20,639,587 (GRCm39) |
F55I |
probably benign |
Het |
| Vmn1r32 |
A |
G |
6: 66,529,939 (GRCm39) |
I279T |
possibly damaging |
Het |
| Zc2hc1a |
A |
G |
3: 7,581,543 (GRCm39) |
D15G |
probably benign |
Het |
| Zfp827 |
C |
A |
8: 79,802,975 (GRCm39) |
P516T |
possibly damaging |
Het |
| Zfyve9 |
A |
T |
4: 108,542,104 (GRCm39) |
|
probably null |
Het |
|
| Other mutations in Pik3r4 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01375:Pik3r4
|
APN |
9 |
105,521,803 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
IGL01617:Pik3r4
|
APN |
9 |
105,532,164 (GRCm39) |
missense |
probably benign |
0.33 |
|
IGL01764:Pik3r4
|
APN |
9 |
105,562,321 (GRCm39) |
splice site |
probably benign |
|
|
IGL01817:Pik3r4
|
APN |
9 |
105,528,021 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01830:Pik3r4
|
APN |
9 |
105,522,154 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01905:Pik3r4
|
APN |
9 |
105,522,077 (GRCm39) |
nonsense |
probably null |
|
|
IGL01947:Pik3r4
|
APN |
9 |
105,563,349 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
IGL01985:Pik3r4
|
APN |
9 |
105,540,244 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL02321:Pik3r4
|
APN |
9 |
105,521,677 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL02389:Pik3r4
|
APN |
9 |
105,527,530 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
IGL02898:Pik3r4
|
APN |
9 |
105,527,605 (GRCm39) |
missense |
probably benign |
0.21 |
|
IGL03037:Pik3r4
|
APN |
9 |
105,528,012 (GRCm39) |
missense |
probably damaging |
1.00 |
|
boteh
|
UTSW |
9 |
105,545,137 (GRCm39) |
splice site |
probably null |
|
|
truth
|
UTSW |
9 |
105,527,805 (GRCm39) |
missense |
probably damaging |
0.98 |
|
verisimilitude
|
UTSW |
9 |
105,555,352 (GRCm39) |
missense |
probably benign |
0.17 |
|
IGL02835:Pik3r4
|
UTSW |
9 |
105,549,905 (GRCm39) |
missense |
probably benign |
0.07 |
|
R0011:Pik3r4
|
UTSW |
9 |
105,521,836 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0312:Pik3r4
|
UTSW |
9 |
105,563,409 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0321:Pik3r4
|
UTSW |
9 |
105,525,906 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0482:Pik3r4
|
UTSW |
9 |
105,546,244 (GRCm39) |
missense |
probably benign |
0.04 |
|
R0645:Pik3r4
|
UTSW |
9 |
105,546,386 (GRCm39) |
splice site |
probably benign |
|
|
R0690:Pik3r4
|
UTSW |
9 |
105,531,175 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R0789:Pik3r4
|
UTSW |
9 |
105,562,366 (GRCm39) |
missense |
probably benign |
0.14 |
|
R0894:Pik3r4
|
UTSW |
9 |
105,544,970 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R0988:Pik3r4
|
UTSW |
9 |
105,564,404 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1123:Pik3r4
|
UTSW |
9 |
105,540,328 (GRCm39) |
missense |
probably benign |
|
|
R1172:Pik3r4
|
UTSW |
9 |
105,540,373 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1174:Pik3r4
|
UTSW |
9 |
105,540,373 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1342:Pik3r4
|
UTSW |
9 |
105,528,100 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1387:Pik3r4
|
UTSW |
9 |
105,521,490 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1480:Pik3r4
|
UTSW |
9 |
105,564,443 (GRCm39) |
missense |
probably benign |
0.39 |
|
R1643:Pik3r4
|
UTSW |
9 |
105,564,351 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R1995:Pik3r4
|
UTSW |
9 |
105,546,364 (GRCm39) |
missense |
probably benign |
0.12 |
|
R2037:Pik3r4
|
UTSW |
9 |
105,527,534 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2165:Pik3r4
|
UTSW |
9 |
105,549,984 (GRCm39) |
missense |
probably benign |
0.05 |
|
R4210:Pik3r4
|
UTSW |
9 |
105,527,957 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
R4515:Pik3r4
|
UTSW |
9 |
105,549,924 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4519:Pik3r4
|
UTSW |
9 |
105,549,924 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4630:Pik3r4
|
UTSW |
9 |
105,532,098 (GRCm39) |
missense |
probably benign |
0.06 |
|
R4632:Pik3r4
|
UTSW |
9 |
105,532,098 (GRCm39) |
missense |
probably benign |
0.06 |
|
R4732:Pik3r4
|
UTSW |
9 |
105,555,375 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R4733:Pik3r4
|
UTSW |
9 |
105,555,375 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R4940:Pik3r4
|
UTSW |
9 |
105,546,193 (GRCm39) |
missense |
probably benign |
0.20 |
|
R5120:Pik3r4
|
UTSW |
9 |
105,546,208 (GRCm39) |
missense |
probably benign |
0.30 |
|
R5169:Pik3r4
|
UTSW |
9 |
105,555,360 (GRCm39) |
missense |
probably benign |
0.14 |
|
R5183:Pik3r4
|
UTSW |
9 |
105,559,507 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R5353:Pik3r4
|
UTSW |
9 |
105,545,137 (GRCm39) |
splice site |
probably null |
|
|
R5463:Pik3r4
|
UTSW |
9 |
105,525,930 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5635:Pik3r4
|
UTSW |
9 |
105,545,024 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5763:Pik3r4
|
UTSW |
9 |
105,546,974 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5830:Pik3r4
|
UTSW |
9 |
105,522,023 (GRCm39) |
nonsense |
probably null |
|
|
R6251:Pik3r4
|
UTSW |
9 |
105,531,247 (GRCm39) |
missense |
probably benign |
|
|
R6468:Pik3r4
|
UTSW |
9 |
105,562,389 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R6611:Pik3r4
|
UTSW |
9 |
105,521,476 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6642:Pik3r4
|
UTSW |
9 |
105,521,845 (GRCm39) |
missense |
probably benign |
0.11 |
|
R6821:Pik3r4
|
UTSW |
9 |
105,527,805 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7039:Pik3r4
|
UTSW |
9 |
105,554,089 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R7144:Pik3r4
|
UTSW |
9 |
105,527,783 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7410:Pik3r4
|
UTSW |
9 |
105,527,790 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7559:Pik3r4
|
UTSW |
9 |
105,555,352 (GRCm39) |
missense |
probably benign |
0.17 |
|
R7561:Pik3r4
|
UTSW |
9 |
105,564,446 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7658:Pik3r4
|
UTSW |
9 |
105,521,710 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7727:Pik3r4
|
UTSW |
9 |
105,547,081 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7871:Pik3r4
|
UTSW |
9 |
105,540,316 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7957:Pik3r4
|
UTSW |
9 |
105,564,408 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8138:Pik3r4
|
UTSW |
9 |
105,546,234 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R8686:Pik3r4
|
UTSW |
9 |
105,535,728 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R8719:Pik3r4
|
UTSW |
9 |
105,559,394 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9091:Pik3r4
|
UTSW |
9 |
105,547,108 (GRCm39) |
missense |
probably benign |
0.35 |
|
R9189:Pik3r4
|
UTSW |
9 |
105,547,038 (GRCm39) |
missense |
probably benign |
0.22 |
|
R9270:Pik3r4
|
UTSW |
9 |
105,547,108 (GRCm39) |
missense |
probably benign |
0.35 |
|
R9439:Pik3r4
|
UTSW |
9 |
105,528,041 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- ATGAGGCGCAGGTTTAACCTCAG -3'
(R):5'- CTGTTCTGTTCCATATGCAGCAAGC -3'
Sequencing Primer
(F):5'- GGCCTTTGTTTTTGACTTCTACC -3'
(R):5'- GGATTTGCTCAGCCATGAAAC -3'
|
| Posted On |
2014-04-24 |
Incidental Mutation