Incidental Mutation 'R1624:Adcy4'
| ID |
174922 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Adcy4
|
| Ensembl Gene |
ENSMUSG00000022220 |
| Gene Name |
adenylate cyclase 4 |
| Synonyms |
|
| MMRRC Submission |
039661-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R1624 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
14 |
| Chromosomal Location |
56006514-56021552 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 56019384 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Alanine
at position 89
(T89A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000130530
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000002398]
[ENSMUST00000022830]
[ENSMUST00000168716]
[ENSMUST00000170223]
[ENSMUST00000178399]
[ENSMUST00000227031]
[ENSMUST00000228476]
|
| AlphaFold |
Q91WF3 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000002398
AA Change: T89A
PolyPhen 2
Score 0.682 (Sensitivity: 0.86; Specificity: 0.92)
|
| SMART Domains |
Protein: ENSMUSP00000002398
Gene: ENSMUSG00000022220
AA Change: T89A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
28 |
48 |
N/A |
INTRINSIC |
|
low complexity region
|
66 |
80 |
N/A |
INTRINSIC |
|
low complexity region
|
145 |
161 |
N/A |
INTRINSIC |
|
CYCc
|
218 |
426 |
1.56e-62 |
SMART |
|
Pfam:DUF1053
|
479 |
581 |
2.4e-35 |
PFAM |
|
transmembrane domain
|
607 |
629 |
N/A |
INTRINSIC |
|
transmembrane domain
|
661 |
683 |
N/A |
INTRINSIC |
|
transmembrane domain
|
717 |
739 |
N/A |
INTRINSIC |
|
transmembrane domain
|
746 |
768 |
N/A |
INTRINSIC |
|
transmembrane domain
|
792 |
809 |
N/A |
INTRINSIC |
|
CYCc
|
835 |
1057 |
4.46e-40 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000022830
|
| SMART Domains |
Protein: ENSMUSP00000022830
Gene: ENSMUSG00000022221
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Pkinase
|
22 |
288 |
2.8e-38 |
PFAM |
|
Pfam:Pkinase_Tyr
|
22 |
288 |
3e-34 |
PFAM |
|
Pfam:RHIM
|
408 |
458 |
2.4e-19 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000168716
|
| SMART Domains |
Protein: ENSMUSP00000126306
Gene: ENSMUSG00000022221
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Pkinase
|
1 |
223 |
1.2e-30 |
PFAM |
|
Pfam:Pkinase_Tyr
|
1 |
224 |
3.1e-27 |
PFAM |
|
Pfam:RHIM
|
344 |
395 |
2.4e-14 |
PFAM |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000170223
AA Change: T89A
PolyPhen 2
Score 0.682 (Sensitivity: 0.86; Specificity: 0.92)
|
| SMART Domains |
Protein: ENSMUSP00000130530
Gene: ENSMUSG00000022220
AA Change: T89A
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
29 |
51 |
N/A |
INTRINSIC |
|
transmembrane domain
|
61 |
80 |
N/A |
INTRINSIC |
|
transmembrane domain
|
92 |
114 |
N/A |
INTRINSIC |
|
transmembrane domain
|
119 |
138 |
N/A |
INTRINSIC |
|
transmembrane domain
|
145 |
162 |
N/A |
INTRINSIC |
|
transmembrane domain
|
172 |
194 |
N/A |
INTRINSIC |
|
CYCc
|
218 |
426 |
1.56e-62 |
SMART |
|
Pfam:DUF1053
|
479 |
581 |
1.6e-24 |
PFAM |
|
transmembrane domain
|
607 |
629 |
N/A |
INTRINSIC |
|
transmembrane domain
|
661 |
683 |
N/A |
INTRINSIC |
|
transmembrane domain
|
717 |
739 |
N/A |
INTRINSIC |
|
transmembrane domain
|
746 |
768 |
N/A |
INTRINSIC |
|
transmembrane domain
|
792 |
809 |
N/A |
INTRINSIC |
|
CYCc
|
835 |
1057 |
4.46e-40 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000178399
|
| SMART Domains |
Protein: ENSMUSP00000137278
Gene: ENSMUSG00000022221
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Pkinase
|
1 |
223 |
1.2e-30 |
PFAM |
|
Pfam:Pkinase_Tyr
|
1 |
224 |
3.1e-27 |
PFAM |
|
Pfam:RHIM
|
344 |
395 |
2.4e-14 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000226361
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000227031
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000228175
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000227072
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000228077
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000228476
|
| Meta Mutation Damage Score |
0.1136 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.3%
- 10x: 95.9%
- 20x: 91.4%
|
| Validation Efficiency |
99% (90/91) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). Mouse studies show that adenylate cyclase 4, along with adenylate cyclases 2 and 3, is expressed in olfactory cilia, suggesting that several different adenylate cyclases may couple to olfactory receptors and that there may be multiple receptor-mediated mechanisms for the generation of cAMP signals. Alternative splicing results in transcript variants. [provided by RefSeq, Nov 2010]
PHENOTYPE: Mice homozygous for disruptions of this gene display a normal phenotype. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 83 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2510009E07Rik |
T |
C |
16: 21,472,496 (GRCm39) |
Y68C |
probably damaging |
Het |
| 6820408C15Rik |
A |
T |
2: 152,276,031 (GRCm39) |
H81L |
probably damaging |
Het |
| Acbd4 |
A |
G |
11: 102,994,785 (GRCm39) |
T48A |
probably damaging |
Het |
| Acp3 |
T |
A |
9: 104,197,200 (GRCm39) |
E146D |
probably benign |
Het |
| Acsm1 |
T |
A |
7: 119,251,796 (GRCm39) |
I307N |
probably damaging |
Het |
| Agl |
T |
C |
3: 116,580,895 (GRCm39) |
T356A |
probably benign |
Het |
| Ago1 |
A |
G |
4: 126,357,534 (GRCm39) |
I47T |
probably damaging |
Het |
| Akr1c6 |
T |
A |
13: 4,496,363 (GRCm39) |
Y75N |
probably benign |
Het |
| Anxa2 |
T |
A |
9: 69,386,990 (GRCm39) |
S92T |
probably benign |
Het |
| Arid4b |
T |
C |
13: 14,358,979 (GRCm39) |
S585P |
probably damaging |
Het |
| Arl4d |
T |
C |
11: 101,557,842 (GRCm39) |
S123P |
possibly damaging |
Het |
| Atad2 |
A |
T |
15: 57,963,415 (GRCm39) |
D1067E |
probably damaging |
Het |
| Brap |
C |
A |
5: 121,820,922 (GRCm39) |
T403K |
possibly damaging |
Het |
| Brwd1 |
A |
T |
16: 95,809,344 (GRCm39) |
N1895K |
possibly damaging |
Het |
| Ccdc187 |
T |
C |
2: 26,171,087 (GRCm39) |
T464A |
probably benign |
Het |
| Ccn6 |
G |
A |
10: 39,029,239 (GRCm39) |
R230W |
probably damaging |
Het |
| Cdh11 |
T |
C |
8: 103,391,233 (GRCm39) |
|
probably benign |
Het |
| Chd9 |
A |
T |
8: 91,725,163 (GRCm39) |
Y691F |
probably benign |
Het |
| Clhc1 |
A |
T |
11: 29,519,287 (GRCm39) |
I365F |
possibly damaging |
Het |
| Col11a1 |
A |
G |
3: 113,951,804 (GRCm39) |
Q1078R |
probably damaging |
Het |
| Creb3 |
G |
A |
4: 43,566,375 (GRCm39) |
V294I |
possibly damaging |
Het |
| Cspg4 |
T |
C |
9: 56,795,754 (GRCm39) |
I1163T |
probably damaging |
Het |
| Cyp3a57 |
A |
C |
5: 145,327,225 (GRCm39) |
|
probably null |
Het |
| Dnah3 |
A |
T |
7: 119,618,918 (GRCm39) |
I1661N |
probably damaging |
Het |
| Dpysl4 |
A |
C |
7: 138,669,469 (GRCm39) |
D49A |
probably damaging |
Het |
| Efhb |
T |
A |
17: 53,733,306 (GRCm39) |
I522F |
probably damaging |
Het |
| Epha4 |
T |
C |
1: 77,376,329 (GRCm39) |
T517A |
probably damaging |
Het |
| Fasn |
A |
G |
11: 120,703,937 (GRCm39) |
S1466P |
probably damaging |
Het |
| Fgd6 |
A |
T |
10: 93,973,298 (GRCm39) |
D1253V |
probably benign |
Het |
| Fjx1 |
G |
A |
2: 102,281,509 (GRCm39) |
A142V |
probably benign |
Het |
| Foxb1 |
T |
C |
9: 69,666,598 (GRCm39) |
T311A |
probably benign |
Het |
| Fpgs |
A |
G |
2: 32,581,200 (GRCm39) |
|
probably null |
Het |
| Gm10024 |
A |
G |
10: 77,547,606 (GRCm39) |
|
probably null |
Het |
| Gnat3 |
A |
T |
5: 18,208,841 (GRCm39) |
T182S |
possibly damaging |
Het |
| Igsf3 |
T |
A |
3: 101,362,543 (GRCm39) |
F875I |
probably benign |
Het |
| Kif13b |
A |
G |
14: 64,976,068 (GRCm39) |
E461G |
probably damaging |
Het |
| Kif23 |
A |
T |
9: 61,832,982 (GRCm39) |
|
probably null |
Het |
| Kntc1 |
G |
A |
5: 123,896,540 (GRCm39) |
R134Q |
possibly damaging |
Het |
| Krt33a |
A |
T |
11: 99,905,072 (GRCm39) |
Y145N |
probably damaging |
Het |
| Lama5 |
A |
G |
2: 179,848,551 (GRCm39) |
V313A |
probably benign |
Het |
| Lamb1 |
T |
C |
12: 31,328,651 (GRCm39) |
|
probably null |
Het |
| Megf6 |
G |
T |
4: 154,261,578 (GRCm39) |
V68L |
probably benign |
Het |
| Mtor |
C |
T |
4: 148,632,133 (GRCm39) |
L2336F |
probably damaging |
Het |
| Naglu |
T |
C |
11: 100,967,351 (GRCm39) |
S434P |
probably damaging |
Het |
| Ncoa7 |
T |
A |
10: 30,580,655 (GRCm39) |
H101L |
possibly damaging |
Het |
| Nlrc4 |
G |
A |
17: 74,752,184 (GRCm39) |
T733I |
possibly damaging |
Het |
| Nr3c2 |
A |
G |
8: 77,636,573 (GRCm39) |
E558G |
probably damaging |
Het |
| Nsun4 |
A |
T |
4: 115,891,397 (GRCm39) |
N327K |
probably benign |
Het |
| Or11g27 |
A |
G |
14: 50,771,100 (GRCm39) |
Y77C |
probably damaging |
Het |
| Or1x2 |
T |
C |
11: 50,917,952 (GRCm39) |
V41A |
probably damaging |
Het |
| Or2m13 |
T |
A |
16: 19,226,454 (GRCm39) |
Y104F |
probably benign |
Het |
| Or4f6 |
T |
A |
2: 111,838,877 (GRCm39) |
Y218F |
probably damaging |
Het |
| Or6b13 |
T |
C |
7: 139,781,864 (GRCm39) |
N273S |
probably damaging |
Het |
| Pdia2 |
T |
A |
17: 26,415,495 (GRCm39) |
I441F |
probably damaging |
Het |
| Phyh |
T |
C |
2: 4,930,494 (GRCm39) |
S74P |
probably benign |
Het |
| Pigo |
A |
G |
4: 43,024,661 (GRCm39) |
L146P |
probably damaging |
Het |
| Plce1 |
A |
G |
19: 38,713,219 (GRCm39) |
D1191G |
probably damaging |
Het |
| Plrg1 |
T |
C |
3: 82,975,301 (GRCm39) |
|
probably benign |
Het |
| Plrg1 |
G |
A |
3: 82,977,051 (GRCm39) |
R364Q |
probably damaging |
Het |
| Polr3b |
T |
C |
10: 84,515,669 (GRCm39) |
L614S |
probably damaging |
Het |
| Pramel16 |
A |
T |
4: 143,676,400 (GRCm39) |
C235S |
possibly damaging |
Het |
| Prrg4 |
A |
G |
2: 104,663,027 (GRCm39) |
V193A |
probably damaging |
Het |
| Prss16 |
T |
A |
13: 22,187,483 (GRCm39) |
E47V |
probably benign |
Het |
| Ptpru |
G |
A |
4: 131,499,861 (GRCm39) |
T1261I |
probably damaging |
Het |
| Pycard |
A |
G |
7: 127,591,970 (GRCm39) |
S124P |
possibly damaging |
Het |
| Riok1 |
C |
A |
13: 38,221,487 (GRCm39) |
D17E |
probably damaging |
Het |
| Scin |
T |
A |
12: 40,177,929 (GRCm39) |
Y102F |
probably benign |
Het |
| Scmh1 |
A |
G |
4: 120,386,425 (GRCm39) |
H655R |
probably damaging |
Het |
| Scyl2 |
A |
T |
10: 89,476,598 (GRCm39) |
N842K |
probably benign |
Het |
| Sec23b |
T |
A |
2: 144,409,049 (GRCm39) |
M211K |
probably benign |
Het |
| Serpina3i |
A |
C |
12: 104,234,897 (GRCm39) |
*409C |
probably null |
Het |
| Sgk2 |
G |
A |
2: 162,839,779 (GRCm39) |
R129H |
probably benign |
Het |
| Slc39a13 |
A |
G |
2: 90,898,871 (GRCm39) |
I80T |
probably damaging |
Het |
| Smarcad1 |
A |
G |
6: 65,029,631 (GRCm39) |
D73G |
probably benign |
Het |
| Spata18 |
A |
C |
5: 73,826,888 (GRCm39) |
T276P |
probably damaging |
Het |
| Srgap1 |
T |
G |
10: 121,691,278 (GRCm39) |
M319L |
probably benign |
Het |
| Stx7 |
T |
A |
10: 24,060,903 (GRCm39) |
V210E |
probably damaging |
Het |
| Tjp2 |
T |
A |
19: 24,108,776 (GRCm39) |
H112L |
probably benign |
Het |
| Tuba8 |
A |
T |
6: 121,197,385 (GRCm39) |
I16F |
probably damaging |
Het |
| Ube3c |
G |
A |
5: 29,851,617 (GRCm39) |
A815T |
probably benign |
Het |
| Vmn2r5 |
A |
T |
3: 64,417,116 (GRCm39) |
V14E |
probably benign |
Het |
| Vmn2r79 |
A |
T |
7: 86,653,247 (GRCm39) |
|
probably null |
Het |
| Zdbf2 |
A |
G |
1: 63,343,018 (GRCm39) |
T466A |
possibly damaging |
Het |
|
| Other mutations in Adcy4 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00917:Adcy4
|
APN |
14 |
56,011,120 (GRCm39) |
splice site |
probably null |
|
|
IGL02406:Adcy4
|
APN |
14 |
56,007,504 (GRCm39) |
missense |
possibly damaging |
0.45 |
|
IGL02503:Adcy4
|
APN |
14 |
56,008,962 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02543:Adcy4
|
APN |
14 |
56,006,627 (GRCm39) |
missense |
probably benign |
|
|
IGL02616:Adcy4
|
APN |
14 |
56,020,971 (GRCm39) |
splice site |
probably null |
|
|
IGL03002:Adcy4
|
APN |
14 |
56,011,013 (GRCm39) |
missense |
probably benign |
0.31 |
|
IGL03026:Adcy4
|
APN |
14 |
56,015,467 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03190:Adcy4
|
APN |
14 |
56,016,510 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03247:Adcy4
|
APN |
14 |
56,007,553 (GRCm39) |
missense |
probably damaging |
1.00 |
|
stressed
|
UTSW |
14 |
56,016,556 (GRCm39) |
splice site |
probably null |
|
|
IGL03098:Adcy4
|
UTSW |
14 |
56,019,038 (GRCm39) |
missense |
probably null |
0.82 |
|
R0098:Adcy4
|
UTSW |
14 |
56,007,284 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R0102:Adcy4
|
UTSW |
14 |
56,008,990 (GRCm39) |
missense |
probably benign |
0.29 |
|
R0396:Adcy4
|
UTSW |
14 |
56,009,745 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0482:Adcy4
|
UTSW |
14 |
56,012,029 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R0634:Adcy4
|
UTSW |
14 |
56,019,054 (GRCm39) |
missense |
probably benign |
|
|
R0691:Adcy4
|
UTSW |
14 |
56,010,104 (GRCm39) |
splice site |
probably benign |
|
|
R0704:Adcy4
|
UTSW |
14 |
56,010,213 (GRCm39) |
missense |
probably benign |
|
|
R0815:Adcy4
|
UTSW |
14 |
56,021,056 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0863:Adcy4
|
UTSW |
14 |
56,021,056 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1446:Adcy4
|
UTSW |
14 |
56,007,480 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1462:Adcy4
|
UTSW |
14 |
56,015,765 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R1462:Adcy4
|
UTSW |
14 |
56,015,765 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R1463:Adcy4
|
UTSW |
14 |
56,016,396 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1799:Adcy4
|
UTSW |
14 |
56,008,929 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1878:Adcy4
|
UTSW |
14 |
56,007,362 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R2007:Adcy4
|
UTSW |
14 |
56,015,770 (GRCm39) |
missense |
possibly damaging |
0.45 |
|
R2156:Adcy4
|
UTSW |
14 |
56,006,627 (GRCm39) |
missense |
probably benign |
0.09 |
|
R2425:Adcy4
|
UTSW |
14 |
56,015,474 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2517:Adcy4
|
UTSW |
14 |
56,019,403 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3882:Adcy4
|
UTSW |
14 |
56,012,003 (GRCm39) |
missense |
probably benign |
0.27 |
|
R4021:Adcy4
|
UTSW |
14 |
56,012,635 (GRCm39) |
splice site |
probably null |
|
|
R4022:Adcy4
|
UTSW |
14 |
56,012,635 (GRCm39) |
splice site |
probably null |
|
|
R4411:Adcy4
|
UTSW |
14 |
56,006,900 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4530:Adcy4
|
UTSW |
14 |
56,016,485 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4560:Adcy4
|
UTSW |
14 |
56,016,407 (GRCm39) |
splice site |
probably null |
|
|
R4704:Adcy4
|
UTSW |
14 |
56,012,482 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R4780:Adcy4
|
UTSW |
14 |
56,012,493 (GRCm39) |
missense |
probably benign |
0.07 |
|
R4860:Adcy4
|
UTSW |
14 |
56,019,384 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R4860:Adcy4
|
UTSW |
14 |
56,019,384 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R4868:Adcy4
|
UTSW |
14 |
56,011,179 (GRCm39) |
missense |
probably benign |
|
|
R4890:Adcy4
|
UTSW |
14 |
56,016,486 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4920:Adcy4
|
UTSW |
14 |
56,016,486 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4948:Adcy4
|
UTSW |
14 |
56,016,486 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4952:Adcy4
|
UTSW |
14 |
56,016,486 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4953:Adcy4
|
UTSW |
14 |
56,016,486 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4987:Adcy4
|
UTSW |
14 |
56,010,934 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4991:Adcy4
|
UTSW |
14 |
56,010,922 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5080:Adcy4
|
UTSW |
14 |
56,009,832 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5620:Adcy4
|
UTSW |
14 |
56,009,824 (GRCm39) |
nonsense |
probably null |
|
|
R5652:Adcy4
|
UTSW |
14 |
56,010,900 (GRCm39) |
missense |
probably benign |
|
|
R5726:Adcy4
|
UTSW |
14 |
56,021,118 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5910:Adcy4
|
UTSW |
14 |
56,016,470 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5958:Adcy4
|
UTSW |
14 |
56,016,556 (GRCm39) |
splice site |
probably null |
|
|
R6280:Adcy4
|
UTSW |
14 |
56,016,500 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6318:Adcy4
|
UTSW |
14 |
56,006,681 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6598:Adcy4
|
UTSW |
14 |
56,007,502 (GRCm39) |
missense |
probably benign |
0.03 |
|
R6947:Adcy4
|
UTSW |
14 |
56,015,848 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R7012:Adcy4
|
UTSW |
14 |
56,017,376 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7147:Adcy4
|
UTSW |
14 |
56,017,182 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7386:Adcy4
|
UTSW |
14 |
56,015,784 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7414:Adcy4
|
UTSW |
14 |
56,019,090 (GRCm39) |
missense |
probably benign |
0.15 |
|
R7431:Adcy4
|
UTSW |
14 |
56,010,129 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7490:Adcy4
|
UTSW |
14 |
56,007,890 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R7552:Adcy4
|
UTSW |
14 |
56,010,922 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7672:Adcy4
|
UTSW |
14 |
56,018,362 (GRCm39) |
missense |
probably benign |
0.14 |
|
R8003:Adcy4
|
UTSW |
14 |
56,019,092 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8042:Adcy4
|
UTSW |
14 |
56,012,696 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8100:Adcy4
|
UTSW |
14 |
56,009,722 (GRCm39) |
nonsense |
probably null |
|
|
R8343:Adcy4
|
UTSW |
14 |
56,012,697 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8801:Adcy4
|
UTSW |
14 |
56,009,452 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8811:Adcy4
|
UTSW |
14 |
56,010,221 (GRCm39) |
missense |
probably benign |
|
|
R8993:Adcy4
|
UTSW |
14 |
56,016,156 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8993:Adcy4
|
UTSW |
14 |
56,008,835 (GRCm39) |
missense |
probably null |
1.00 |
|
R9026:Adcy4
|
UTSW |
14 |
56,016,426 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0025:Adcy4
|
UTSW |
14 |
56,007,848 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1088:Adcy4
|
UTSW |
14 |
56,018,413 (GRCm39) |
missense |
probably benign |
0.06 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGCGCCCAGGGTCTAAATTTGAG -3'
(R):5'- TGCAAATAGCCAAGAGTAGCCCG -3'
Sequencing Primer
(F):5'- CCAGGGTCTAAATTTGAGGTTCAC -3'
(R):5'- cccccaccattccccac -3'
|
| Posted On |
2014-04-24 |
Incidental Mutation