Incidental Mutation 'R1595:Lrrc7'
| ID |
175713 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Lrrc7
|
| Ensembl Gene |
ENSMUSG00000028176 |
| Gene Name |
leucine rich repeat containing 7 |
| Synonyms |
densin |
| MMRRC Submission |
039632-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.798)
|
| Stock # |
R1595 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
3 |
| Chromosomal Location |
157788528-158267858 bp(-) (GRCm39) |
| Type of Mutation |
nonsense |
| DNA Base Change (assembly) |
G to A
at 157882914 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamine to Stop codon
at position 448
(Q448*)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000106044]
[ENSMUST00000199890]
[ENSMUST00000200137]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably null
Transcript: ENSMUST00000106044
AA Change: Q460*
|
| SMART Domains |
Protein: ENSMUSP00000101659
Gene: ENSMUSG00000028176
AA Change: Q460*
| Domain | Start | End | E-Value | Type |
|---|
|
LRR
|
53 |
73 |
3.65e0 |
SMART |
|
LRR
|
96 |
118 |
2.2e1 |
SMART |
|
LRR
|
142 |
164 |
4.21e1 |
SMART |
|
LRR
|
165 |
187 |
7.36e0 |
SMART |
|
LRR
|
188 |
210 |
7.05e-1 |
SMART |
|
LRR
|
211 |
233 |
3.09e1 |
SMART |
|
LRR
|
234 |
257 |
4.21e1 |
SMART |
|
LRR
|
258 |
279 |
2.61e2 |
SMART |
|
LRR
|
280 |
303 |
3.52e-1 |
SMART |
|
LRR
|
326 |
349 |
1.99e0 |
SMART |
|
LRR
|
372 |
394 |
2.63e0 |
SMART |
|
low complexity region
|
466 |
476 |
N/A |
INTRINSIC |
|
low complexity region
|
692 |
705 |
N/A |
INTRINSIC |
|
Blast:PDZ
|
708 |
736 |
1e-5 |
BLAST |
|
low complexity region
|
787 |
797 |
N/A |
INTRINSIC |
|
low complexity region
|
864 |
878 |
N/A |
INTRINSIC |
|
Blast:PDZ
|
1349 |
1378 |
2e-11 |
BLAST |
|
PDZ
|
1460 |
1540 |
1.33e-19 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000198578
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000199890
AA Change: Q460*
|
| SMART Domains |
Protein: ENSMUSP00000142440
Gene: ENSMUSG00000028176
AA Change: Q460*
| Domain | Start | End | E-Value | Type |
|---|
|
LRR
|
53 |
73 |
3.65e0 |
SMART |
|
LRR
|
96 |
118 |
2.2e1 |
SMART |
|
LRR
|
142 |
164 |
4.21e1 |
SMART |
|
LRR
|
165 |
187 |
7.36e0 |
SMART |
|
LRR
|
188 |
210 |
7.05e-1 |
SMART |
|
LRR
|
211 |
233 |
3.09e1 |
SMART |
|
LRR
|
234 |
257 |
4.21e1 |
SMART |
|
LRR
|
258 |
279 |
2.61e2 |
SMART |
|
LRR
|
280 |
303 |
3.52e-1 |
SMART |
|
LRR
|
326 |
349 |
1.99e0 |
SMART |
|
LRR
|
372 |
394 |
2.63e0 |
SMART |
|
low complexity region
|
466 |
476 |
N/A |
INTRINSIC |
|
low complexity region
|
692 |
705 |
N/A |
INTRINSIC |
|
Blast:PDZ
|
708 |
736 |
9e-6 |
BLAST |
|
low complexity region
|
787 |
797 |
N/A |
INTRINSIC |
|
low complexity region
|
864 |
878 |
N/A |
INTRINSIC |
|
Blast:PDZ
|
1328 |
1364 |
1e-15 |
BLAST |
|
low complexity region
|
1374 |
1387 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000200137
AA Change: Q460*
|
| SMART Domains |
Protein: ENSMUSP00000142498
Gene: ENSMUSG00000028176
AA Change: Q460*
| Domain | Start | End | E-Value | Type |
|---|
|
LRR
|
52 |
69 |
7.6e-1 |
SMART |
|
LRR
|
73 |
92 |
4.2e-1 |
SMART |
|
LRR
|
96 |
115 |
3.4e-1 |
SMART |
|
LRR
|
142 |
164 |
1.8e-1 |
SMART |
|
LRR
|
165 |
184 |
1.5e-1 |
SMART |
|
LRR
|
188 |
207 |
2e-2 |
SMART |
|
LRR
|
211 |
233 |
1.3e-1 |
SMART |
|
LRR
|
234 |
257 |
1.7e-1 |
SMART |
|
LRR
|
257 |
276 |
1e0 |
SMART |
|
LRR
|
280 |
299 |
3.1e-2 |
SMART |
|
LRR
|
303 |
322 |
6.6e-1 |
SMART |
|
LRR
|
326 |
345 |
2.1e-1 |
SMART |
|
LRR
|
372 |
391 |
1.2e-1 |
SMART |
|
low complexity region
|
466 |
476 |
N/A |
INTRINSIC |
|
low complexity region
|
692 |
705 |
N/A |
INTRINSIC |
|
Blast:PDZ
|
708 |
736 |
1e-5 |
BLAST |
|
low complexity region
|
787 |
797 |
N/A |
INTRINSIC |
|
low complexity region
|
864 |
878 |
N/A |
INTRINSIC |
|
Blast:PDZ
|
1302 |
1331 |
2e-11 |
BLAST |
|
PDZ
|
1413 |
1493 |
6.4e-22 |
SMART |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000200196
AA Change: Q448*
|
| Meta Mutation Damage Score |
0.9717 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.3%
- 10x: 96.1%
- 20x: 92.1%
|
| Validation Efficiency |
97% (77/79) |
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a knock-out allele exhibit limb grasping, reduced long term depression, increased anxiety, increased aggression towards other mice, impaired spatial memory, decreased prepulse inhibition, decreased nesting building behavior, and abnormal dendritic spines. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(2) : Gene trapped(2) |
| Other mutations in this stock |
Total: 72 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abcb6 |
C |
T |
1: 75,153,944 (GRCm39) |
|
probably null |
Het |
| Abcc10 |
G |
T |
17: 46,633,164 (GRCm39) |
P556H |
probably damaging |
Het |
| Abcc9 |
A |
T |
6: 142,578,821 (GRCm39) |
D914E |
probably benign |
Het |
| Adgrf4 |
A |
G |
17: 42,978,764 (GRCm39) |
V193A |
probably benign |
Het |
| Adm |
A |
T |
7: 110,228,298 (GRCm39) |
T160S |
probably damaging |
Het |
| Ammecr1l |
T |
C |
18: 31,905,173 (GRCm39) |
|
probably null |
Het |
| Angpt2 |
T |
C |
8: 18,748,129 (GRCm39) |
D377G |
probably damaging |
Het |
| Ankfn1 |
A |
G |
11: 89,313,593 (GRCm39) |
|
probably null |
Het |
| Arhgap30 |
T |
G |
1: 171,235,909 (GRCm39) |
M761R |
probably benign |
Het |
| Asb4 |
T |
G |
6: 5,390,692 (GRCm39) |
N28K |
probably damaging |
Het |
| Cd177 |
A |
T |
7: 24,444,389 (GRCm39) |
D696E |
probably benign |
Het |
| Cd200 |
G |
A |
16: 45,215,214 (GRCm39) |
T123I |
probably benign |
Het |
| Cfap70 |
A |
G |
14: 20,497,604 (GRCm39) |
V50A |
probably benign |
Het |
| Chaf1b |
T |
C |
16: 93,701,987 (GRCm39) |
|
probably null |
Het |
| Chgb |
A |
C |
2: 132,635,657 (GRCm39) |
D533A |
probably benign |
Het |
| Col12a1 |
A |
G |
9: 79,509,536 (GRCm39) |
Y3041H |
probably damaging |
Het |
| Crot |
T |
C |
5: 9,024,186 (GRCm39) |
N337D |
probably benign |
Het |
| Csad |
G |
A |
15: 102,086,217 (GRCm39) |
A51V |
probably damaging |
Het |
| Cstdc7 |
T |
C |
18: 42,306,454 (GRCm39) |
M7T |
probably benign |
Het |
| Cyp2b9 |
A |
G |
7: 25,900,332 (GRCm39) |
Y380C |
possibly damaging |
Het |
| Dpysl2 |
G |
T |
14: 67,052,952 (GRCm39) |
A299E |
probably damaging |
Het |
| Efcc1 |
A |
G |
6: 87,708,440 (GRCm39) |
E189G |
probably damaging |
Het |
| Egfr |
T |
C |
11: 16,856,847 (GRCm39) |
I940T |
probably damaging |
Het |
| Etnk2 |
T |
G |
1: 133,300,917 (GRCm39) |
L228R |
possibly damaging |
Het |
| Fitm2 |
A |
G |
2: 163,311,610 (GRCm39) |
I201T |
probably benign |
Het |
| Foxo1 |
A |
T |
3: 52,253,375 (GRCm39) |
M513L |
probably benign |
Het |
| Galnt16 |
A |
T |
12: 80,637,410 (GRCm39) |
K379I |
probably damaging |
Het |
| Gm57858 |
C |
T |
3: 36,073,146 (GRCm39) |
A379T |
probably damaging |
Het |
| Gtf2a1 |
T |
A |
12: 91,556,323 (GRCm39) |
N6Y |
probably damaging |
Het |
| Kcnc1 |
G |
A |
7: 46,077,010 (GRCm39) |
V271M |
probably benign |
Het |
| Klhdc8b |
T |
A |
9: 108,328,362 (GRCm39) |
D30V |
probably damaging |
Het |
| Med29 |
T |
C |
7: 28,091,928 (GRCm39) |
D54G |
probably damaging |
Het |
| Mfn2 |
T |
C |
4: 147,979,153 (GRCm39) |
T60A |
probably benign |
Het |
| Mroh1 |
T |
C |
15: 76,317,730 (GRCm39) |
|
probably benign |
Het |
| Mxd1 |
A |
T |
6: 86,628,453 (GRCm39) |
V149E |
possibly damaging |
Het |
| Naip6 |
A |
T |
13: 100,435,602 (GRCm39) |
Y974N |
probably damaging |
Het |
| Ndn |
C |
T |
7: 61,998,256 (GRCm39) |
P34L |
probably benign |
Het |
| Nhsl1 |
G |
T |
10: 18,402,096 (GRCm39) |
K1107N |
probably damaging |
Het |
| Nlrc3 |
T |
C |
16: 3,783,166 (GRCm39) |
E81G |
probably benign |
Het |
| Or10al3 |
G |
T |
17: 38,012,004 (GRCm39) |
A148S |
probably benign |
Het |
| Or9e1 |
G |
T |
11: 58,732,478 (GRCm39) |
M179I |
probably benign |
Het |
| Osbpl5 |
C |
T |
7: 143,256,955 (GRCm39) |
V392M |
possibly damaging |
Het |
| Pcdhb22 |
T |
A |
18: 37,653,506 (GRCm39) |
V401E |
probably damaging |
Het |
| Pcm1 |
T |
A |
8: 41,762,672 (GRCm39) |
H1444Q |
probably damaging |
Het |
| Pdlim2 |
A |
G |
14: 70,402,193 (GRCm39) |
Y308H |
probably damaging |
Het |
| Phf14 |
T |
G |
6: 11,988,752 (GRCm39) |
L664R |
possibly damaging |
Het |
| Phkb |
T |
C |
8: 86,753,182 (GRCm39) |
|
probably benign |
Het |
| Ptchd3 |
T |
A |
11: 121,721,420 (GRCm39) |
F98I |
probably damaging |
Het |
| Ptprt |
C |
T |
2: 161,652,469 (GRCm39) |
|
probably null |
Het |
| Rbp3 |
A |
T |
14: 33,678,155 (GRCm39) |
H701L |
possibly damaging |
Het |
| Rgl1 |
T |
C |
1: 152,550,774 (GRCm39) |
|
probably benign |
Het |
| Satb1 |
A |
T |
17: 52,089,729 (GRCm39) |
S373T |
possibly damaging |
Het |
| Scn3a |
T |
A |
2: 65,329,323 (GRCm39) |
Y769F |
probably damaging |
Het |
| Senp7 |
A |
G |
16: 56,005,131 (GRCm39) |
I922V |
probably damaging |
Het |
| Serpina3g |
A |
G |
12: 104,205,531 (GRCm39) |
E90G |
probably benign |
Het |
| Sh3rf2 |
C |
T |
18: 42,244,353 (GRCm39) |
T273I |
probably damaging |
Het |
| Slc15a3 |
A |
G |
19: 10,831,675 (GRCm39) |
T350A |
probably benign |
Het |
| Socs5 |
T |
C |
17: 87,441,623 (GRCm39) |
C188R |
probably damaging |
Het |
| Tacr1 |
A |
G |
6: 82,380,723 (GRCm39) |
T45A |
probably benign |
Het |
| Th |
A |
G |
7: 142,450,745 (GRCm39) |
V117A |
probably benign |
Het |
| Thpo |
C |
A |
16: 20,547,206 (GRCm39) |
D81Y |
probably damaging |
Het |
| Tmem229b-ps |
A |
G |
10: 53,351,385 (GRCm39) |
|
noncoding transcript |
Het |
| Trpc4 |
A |
G |
3: 54,223,236 (GRCm39) |
E724G |
probably benign |
Het |
| Ttn |
T |
C |
2: 76,576,977 (GRCm39) |
T24639A |
probably damaging |
Het |
| Ulk4 |
A |
G |
9: 120,873,904 (GRCm39) |
S1176P |
probably damaging |
Het |
| Urgcp |
T |
C |
11: 5,667,447 (GRCm39) |
D297G |
probably damaging |
Het |
| Vmn1r168 |
G |
A |
7: 23,240,620 (GRCm39) |
G159D |
probably damaging |
Het |
| Vmn1r67 |
A |
T |
7: 10,181,597 (GRCm39) |
N226I |
probably benign |
Het |
| Vmn2r27 |
T |
C |
6: 124,208,574 (GRCm39) |
E57G |
probably benign |
Het |
| Zdhhc14 |
G |
T |
17: 5,543,831 (GRCm39) |
R37L |
probably benign |
Het |
| Zfp512b |
G |
A |
2: 181,230,229 (GRCm39) |
T499I |
probably damaging |
Het |
| Zmym2 |
A |
T |
14: 57,158,187 (GRCm39) |
K575N |
probably benign |
Het |
|
| Other mutations in Lrrc7 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00594:Lrrc7
|
APN |
3 |
157,892,647 (GRCm39) |
missense |
probably benign |
0.07 |
|
IGL00644:Lrrc7
|
APN |
3 |
157,908,005 (GRCm39) |
nonsense |
probably null |
|
|
IGL00822:Lrrc7
|
APN |
3 |
157,891,111 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL00927:Lrrc7
|
APN |
3 |
157,866,727 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL00946:Lrrc7
|
APN |
3 |
157,866,993 (GRCm39) |
missense |
probably benign |
0.07 |
|
IGL00948:Lrrc7
|
APN |
3 |
157,867,194 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01838:Lrrc7
|
APN |
3 |
157,891,100 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01874:Lrrc7
|
APN |
3 |
157,946,080 (GRCm39) |
splice site |
probably benign |
|
|
IGL02514:Lrrc7
|
APN |
3 |
157,865,929 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02545:Lrrc7
|
APN |
3 |
157,891,011 (GRCm39) |
splice site |
probably benign |
|
|
IGL02665:Lrrc7
|
APN |
3 |
157,866,742 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03129:Lrrc7
|
APN |
3 |
157,866,696 (GRCm39) |
missense |
probably benign |
0.02 |
|
N/A:Lrrc7
|
UTSW |
3 |
157,865,977 (GRCm39) |
missense |
probably benign |
|
|
R0021:Lrrc7
|
UTSW |
3 |
157,866,298 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0041:Lrrc7
|
UTSW |
3 |
157,869,897 (GRCm39) |
splice site |
probably benign |
|
|
R0255:Lrrc7
|
UTSW |
3 |
157,866,475 (GRCm39) |
nonsense |
probably null |
|
|
R0278:Lrrc7
|
UTSW |
3 |
157,885,432 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R0409:Lrrc7
|
UTSW |
3 |
157,867,063 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
R0612:Lrrc7
|
UTSW |
3 |
157,869,990 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0866:Lrrc7
|
UTSW |
3 |
157,869,903 (GRCm39) |
splice site |
probably benign |
|
|
R1077:Lrrc7
|
UTSW |
3 |
157,866,780 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1103:Lrrc7
|
UTSW |
3 |
157,854,343 (GRCm39) |
splice site |
probably benign |
|
|
R1157:Lrrc7
|
UTSW |
3 |
157,865,892 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1187:Lrrc7
|
UTSW |
3 |
157,866,039 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1301:Lrrc7
|
UTSW |
3 |
157,840,968 (GRCm39) |
missense |
probably benign |
0.20 |
|
R1433:Lrrc7
|
UTSW |
3 |
157,882,943 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1450:Lrrc7
|
UTSW |
3 |
157,892,681 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R1659:Lrrc7
|
UTSW |
3 |
157,867,045 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1693:Lrrc7
|
UTSW |
3 |
157,790,170 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1774:Lrrc7
|
UTSW |
3 |
157,865,929 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R2273:Lrrc7
|
UTSW |
3 |
157,892,696 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2276:Lrrc7
|
UTSW |
3 |
157,885,429 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2302:Lrrc7
|
UTSW |
3 |
157,840,881 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2326:Lrrc7
|
UTSW |
3 |
157,876,298 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2371:Lrrc7
|
UTSW |
3 |
157,866,697 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2383:Lrrc7
|
UTSW |
3 |
157,869,593 (GRCm39) |
missense |
probably benign |
|
|
R2679:Lrrc7
|
UTSW |
3 |
157,880,745 (GRCm39) |
nonsense |
probably null |
|
|
R2698:Lrrc7
|
UTSW |
3 |
157,841,028 (GRCm39) |
missense |
probably benign |
0.22 |
|
R2858:Lrrc7
|
UTSW |
3 |
157,867,362 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3758:Lrrc7
|
UTSW |
3 |
157,869,602 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3791:Lrrc7
|
UTSW |
3 |
157,869,593 (GRCm39) |
missense |
probably benign |
|
|
R3805:Lrrc7
|
UTSW |
3 |
157,891,130 (GRCm39) |
missense |
probably benign |
0.10 |
|
R3806:Lrrc7
|
UTSW |
3 |
157,891,130 (GRCm39) |
missense |
probably benign |
0.10 |
|
R3807:Lrrc7
|
UTSW |
3 |
157,891,130 (GRCm39) |
missense |
probably benign |
0.10 |
|
R3892:Lrrc7
|
UTSW |
3 |
157,866,333 (GRCm39) |
missense |
probably benign |
0.08 |
|
R3912:Lrrc7
|
UTSW |
3 |
157,997,589 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3913:Lrrc7
|
UTSW |
3 |
157,997,589 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3963:Lrrc7
|
UTSW |
3 |
157,866,042 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4665:Lrrc7
|
UTSW |
3 |
158,024,045 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4666:Lrrc7
|
UTSW |
3 |
158,024,045 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4671:Lrrc7
|
UTSW |
3 |
157,908,132 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R4688:Lrrc7
|
UTSW |
3 |
157,854,242 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4725:Lrrc7
|
UTSW |
3 |
158,024,045 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4726:Lrrc7
|
UTSW |
3 |
158,024,045 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4728:Lrrc7
|
UTSW |
3 |
158,024,045 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4783:Lrrc7
|
UTSW |
3 |
157,832,850 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4867:Lrrc7
|
UTSW |
3 |
157,866,642 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4907:Lrrc7
|
UTSW |
3 |
157,866,877 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5032:Lrrc7
|
UTSW |
3 |
157,887,217 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R5107:Lrrc7
|
UTSW |
3 |
157,867,533 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5295:Lrrc7
|
UTSW |
3 |
157,876,376 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5348:Lrrc7
|
UTSW |
3 |
157,880,963 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5468:Lrrc7
|
UTSW |
3 |
158,024,073 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5778:Lrrc7
|
UTSW |
3 |
157,876,380 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5897:Lrrc7
|
UTSW |
3 |
157,869,990 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6179:Lrrc7
|
UTSW |
3 |
158,059,069 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6312:Lrrc7
|
UTSW |
3 |
157,866,246 (GRCm39) |
missense |
probably benign |
0.04 |
|
R6313:Lrrc7
|
UTSW |
3 |
157,866,373 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6366:Lrrc7
|
UTSW |
3 |
157,841,012 (GRCm39) |
missense |
probably benign |
0.04 |
|
R6389:Lrrc7
|
UTSW |
3 |
157,891,063 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6638:Lrrc7
|
UTSW |
3 |
157,840,940 (GRCm39) |
missense |
probably benign |
0.20 |
|
R6956:Lrrc7
|
UTSW |
3 |
157,994,668 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6969:Lrrc7
|
UTSW |
3 |
157,862,550 (GRCm39) |
missense |
probably benign |
0.19 |
|
R7073:Lrrc7
|
UTSW |
3 |
157,832,884 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7313:Lrrc7
|
UTSW |
3 |
157,866,111 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7365:Lrrc7
|
UTSW |
3 |
157,903,798 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7398:Lrrc7
|
UTSW |
3 |
157,997,595 (GRCm39) |
nonsense |
probably null |
|
|
R7403:Lrrc7
|
UTSW |
3 |
157,854,311 (GRCm39) |
nonsense |
probably null |
|
|
R7407:Lrrc7
|
UTSW |
3 |
157,840,878 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7427:Lrrc7
|
UTSW |
3 |
157,903,778 (GRCm39) |
missense |
probably benign |
0.06 |
|
R7453:Lrrc7
|
UTSW |
3 |
157,891,046 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7461:Lrrc7
|
UTSW |
3 |
157,892,657 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7807:Lrrc7
|
UTSW |
3 |
157,866,124 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7872:Lrrc7
|
UTSW |
3 |
158,059,099 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8215:Lrrc7
|
UTSW |
3 |
157,915,387 (GRCm39) |
missense |
probably benign |
|
|
R8367:Lrrc7
|
UTSW |
3 |
157,908,007 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R8867:Lrrc7
|
UTSW |
3 |
157,867,521 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8880:Lrrc7
|
UTSW |
3 |
157,867,381 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8941:Lrrc7
|
UTSW |
3 |
157,869,593 (GRCm39) |
missense |
probably benign |
|
|
R8958:Lrrc7
|
UTSW |
3 |
157,946,138 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9068:Lrrc7
|
UTSW |
3 |
157,946,138 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9069:Lrrc7
|
UTSW |
3 |
157,946,138 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9180:Lrrc7
|
UTSW |
3 |
157,867,011 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R9193:Lrrc7
|
UTSW |
3 |
158,059,011 (GRCm39) |
nonsense |
probably null |
|
|
R9309:Lrrc7
|
UTSW |
3 |
157,915,361 (GRCm39) |
nonsense |
probably null |
|
|
R9418:Lrrc7
|
UTSW |
3 |
157,908,023 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R9474:Lrrc7
|
UTSW |
3 |
157,841,028 (GRCm39) |
missense |
probably benign |
0.22 |
|
R9515:Lrrc7
|
UTSW |
3 |
157,867,105 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9635:Lrrc7
|
UTSW |
3 |
157,946,138 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9639:Lrrc7
|
UTSW |
3 |
157,946,138 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9682:Lrrc7
|
UTSW |
3 |
157,882,954 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R9731:Lrrc7
|
UTSW |
3 |
157,880,888 (GRCm39) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- ACTGCAACCTTCCAGAGAGGTCAC -3'
(R):5'- TCCAGAGACGGGAATGCTCCAATC -3'
Sequencing Primer
(F):5'- TCCAGAGAGGTCACTCAGTGTATC -3'
(R):5'- TAGGGAAGCCCACTCTTATGC -3'
|
| Posted On |
2014-04-24 |
Incidental Mutation