Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01843:Pcdha11'

178099

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Pcdha11

Ensembl Gene

ENSMUSG00000102206

Gene Name

protocadherin alpha 11

Synonyms

A830022B16Rik, Cnr7, Crnr7

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.133) question?

Stock #

IGL01843

Quality Score

Status

Chromosome

Chromosomal Location

37143911-37320710 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

C to T at 37145886 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Threonine to Isoleucine at position 659 (T659I)

Ref Sequence

ENSEMBL: ENSMUSP00000111321 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000070797] [ENSMUST00000115657] [ENSMUST00000115658] [ENSMUST00000115659] [ENSMUST00000115661] [ENSMUST00000115662] [ENSMUST00000192447] [ENSMUST00000192512] [ENSMUST00000192631] [ENSMUST00000192168] [ENSMUST00000193389] [ENSMUST00000193839] [ENSMUST00000194544] [ENSMUST00000192295] [ENSMUST00000194038] [ENSMUST00000192503] [ENSMUST00000193777] [ENSMUST00000194751] [ENSMUST00000195590]

AlphaFold

Q91Y19

Predicted Effect

probably benign
Transcript: ENSMUST00000070797

SMART Domains

Protein: ENSMUSP00000068828
Gene: ENSMUSG00000103442

Domain	Start	End	E-Value	Type
CA	22	132	3.09e-2	SMART
CA	156	241	6.14e-20	SMART
CA	265	349	3.92e-27	SMART
CA	373	454	4.94e-24	SMART
CA	478	564	1e-24	SMART
CA	592	672	4.55e-14	SMART
transmembrane domain	694	716	N/A	INTRINSIC
Pfam:Cadherin_tail	797	931	5.3e-58	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000097612

Predicted Effect

probably benign
Transcript: ENSMUST00000115657
AA Change: T659I

PolyPhen 2 Score 0.279 (Sensitivity: 0.91; Specificity: 0.88)

SMART Domains

Protein: ENSMUSP00000111321
Gene: ENSMUSG00000102206
AA Change: T659I

Domain	Start	End	E-Value	Type
CA	21	131	2.95e-2	SMART
CA	155	240	7.44e-19	SMART
CA	264	347	5.63e-28	SMART
CA	371	452	3.14e-26	SMART
CA	476	562	1.42e-24	SMART
CA	593	675	1.03e-12	SMART
transmembrane domain	697	719	N/A	INTRINSIC
low complexity region	783	794	N/A	INTRINSIC
low complexity region	918	942	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000115658

SMART Domains

Protein: ENSMUSP00000111322
Gene: ENSMUSG00000007440

Domain	Start	End	E-Value	Type
low complexity region	15	21	N/A	INTRINSIC
CA	46	132	6.34e-2	SMART
CA	156	241	4.65e-20	SMART
CA	265	349	1.25e-25	SMART
CA	373	454	9.22e-24	SMART
CA	478	564	4.3e-24	SMART
CA	595	678	5.07e-12	SMART
low complexity region	706	721	N/A	INTRINSIC
Pfam:Cadherin_tail	795	929	5.3e-58	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000115659

SMART Domains

Protein: ENSMUSP00000111323
Gene: ENSMUSG00000103770

Domain	Start	End	E-Value	Type
low complexity region	44	51	N/A	INTRINSIC
CA	75	161	2.46e-2	SMART
CA	185	270	8.1e-20	SMART
CA	294	378	1.69e-22	SMART
CA	402	483	1.52e-24	SMART
CA	507	593	5.68e-24	SMART
CA	624	705	6.69e-12	SMART
transmembrane domain	727	749	N/A	INTRINSIC
Pfam:Cadherin_tail	828	962	5.6e-58	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000115661

SMART Domains

Protein: ENSMUSP00000111325
Gene: ENSMUSG00000103458

Domain	Start	End	E-Value	Type
CA	20	131	5.3e-2	SMART
CA	155	240	1.51e-19	SMART
CA	264	348	7.6e-25	SMART
CA	372	453	1.42e-24	SMART
CA	477	563	1.42e-24	SMART
CA	594	674	4.12e-12	SMART
low complexity region	706	721	N/A	INTRINSIC
Pfam:Cadherin_tail	796	930	3.9e-58	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000115662

SMART Domains

Protein: ENSMUSP00000111326
Gene: ENSMUSG00000104148

Domain	Start	End	E-Value	Type
CA	45	131	6.34e-2	SMART
CA	155	240	2.98e-18	SMART
CA	264	348	2.17e-29	SMART
CA	372	453	2.84e-24	SMART
CA	477	563	5.02e-25	SMART
CA	594	675	8.16e-16	SMART
transmembrane domain	695	717	N/A	INTRINSIC
low complexity region	916	940	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000192447
AA Change: T659I

PolyPhen 2 Score 0.144 (Sensitivity: 0.92; Specificity: 0.86)

SMART Domains

Protein: ENSMUSP00000142270
Gene: ENSMUSG00000102206
AA Change: T659I

Domain	Start	End	E-Value	Type
CA	21	131	1.5e-4	SMART
CA	155	240	3.6e-21	SMART
CA	264	347	2.8e-30	SMART
CA	371	452	1.5e-28	SMART
CA	476	562	6.8e-27	SMART
CA	593	675	4.9e-15	SMART
transmembrane domain	697	719	N/A	INTRINSIC
low complexity region	783	794	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000194050

Predicted Effect

probably benign
Transcript: ENSMUST00000192512

SMART Domains

Protein: ENSMUSP00000141408
Gene: ENSMUSG00000104252

Domain	Start	End	E-Value	Type
CA	20	131	5.3e-2	SMART
CA	155	240	1.51e-19	SMART
CA	264	348	7.6e-25	SMART
CA	372	453	1.42e-24	SMART
CA	477	563	1.42e-24	SMART
CA	594	674	4.12e-12	SMART
low complexity region	706	721	N/A	INTRINSIC
low complexity region	915	939	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000192631

SMART Domains

Protein: ENSMUSP00000142156
Gene: ENSMUSG00000104318

Domain	Start	End	E-Value	Type
CA	21	131	2.58e-2	SMART
CA	155	240	4.27e-19	SMART
CA	264	348	1.42e-24	SMART
CA	372	453	9.36e-25	SMART
CA	477	563	1.42e-24	SMART
CA	594	671	4.03e-6	SMART
transmembrane domain	696	718	N/A	INTRINSIC
low complexity region	905	929	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000193984

Predicted Effect

probably benign
Transcript: ENSMUST00000193856

Predicted Effect

probably benign
Transcript: ENSMUST00000192168

SMART Domains

Protein: ENSMUSP00000142293
Gene: ENSMUSG00000103092

Domain	Start	End	E-Value	Type
CA	21	131	2.2e-2	SMART
CA	155	240	2.05e-21	SMART
CA	264	348	8.81e-21	SMART
CA	372	453	2.01e-24	SMART
CA	477	563	1.42e-24	SMART
CA	591	673	1.63e-15	SMART
transmembrane domain	693	715	N/A	INTRINSIC
low complexity region	902	926	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000193389

SMART Domains

Protein: ENSMUSP00000141459
Gene: ENSMUSG00000103707

Domain	Start	End	E-Value	Type
CA	21	131	5.67e-2	SMART
CA	155	240	4.72e-21	SMART
CA	264	348	1.9e-25	SMART
CA	372	453	3.31e-25	SMART
CA	477	563	1.42e-24	SMART
CA	594	676	5.91e-13	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000193839

SMART Domains

Protein: ENSMUSP00000142308
Gene: ENSMUSG00000103442

Domain	Start	End	E-Value	Type
CA	22	132	3.09e-2	SMART
CA	156	241	6.14e-20	SMART
CA	265	349	3.92e-27	SMART
CA	373	454	4.94e-24	SMART
CA	478	564	1e-24	SMART
CA	592	672	4.55e-14	SMART
transmembrane domain	694	716	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000194544

SMART Domains

Protein: ENSMUSP00000141847
Gene: ENSMUSG00000102836

Domain	Start	End	E-Value	Type
Blast:CA	18	66	5e-20	BLAST

Predicted Effect

probably benign
Transcript: ENSMUST00000192295

SMART Domains

Protein: ENSMUSP00000142103
Gene: ENSMUSG00000104252

Domain	Start	End	E-Value	Type
CA	20	131	5.3e-2	SMART
CA	155	240	1.51e-19	SMART
CA	264	348	7.6e-25	SMART
CA	372	453	1.42e-24	SMART
CA	477	568	5.38e-1	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000194038

SMART Domains

Protein: ENSMUSP00000142159
Gene: ENSMUSG00000103800

Domain	Start	End	E-Value	Type
CA	20	131	6.34e-2	SMART
CA	155	240	4.27e-19	SMART
CA	264	348	2.04e-25	SMART
CA	372	453	2.84e-24	SMART
CA	477	563	9.88e-24	SMART
CA	594	676	8.62e-15	SMART
transmembrane domain	699	721	N/A	INTRINSIC
low complexity region	914	938	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000192503

SMART Domains

Protein: ENSMUSP00000141989
Gene: ENSMUSG00000102312

Domain	Start	End	E-Value	Type
low complexity region	11	17	N/A	INTRINSIC
CA	42	128	3.78e-2	SMART
CA	152	237	8.94e-22	SMART
CA	261	345	3.74e-24	SMART
CA	369	450	1.09e-25	SMART
CA	474	560	1.42e-24	SMART
CA	588	670	2.96e-13	SMART
transmembrane domain	692	714	N/A	INTRINSIC
low complexity region	910	934	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000193777

SMART Domains

Protein: ENSMUSP00000141587
Gene: ENSMUSG00000103707

Domain	Start	End	E-Value	Type
CA	21	131	5.67e-2	SMART
CA	155	240	4.72e-21	SMART
CA	264	348	1.9e-25	SMART
CA	372	453	3.31e-25	SMART
CA	477	563	1.42e-24	SMART
CA	594	676	5.91e-13	SMART
low complexity region	914	938	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000195341

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000194691

Predicted Effect

probably benign
Transcript: ENSMUST00000194751

SMART Domains

Protein: ENSMUSP00000142285
Gene: ENSMUSG00000103707

Domain	Start	End	E-Value	Type
low complexity region	15	21	N/A	INTRINSIC
Pfam:Cadherin_2	29	112	4.5e-32	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000195590

SMART Domains

Protein: ENSMUSP00000141355
Gene: ENSMUSG00000104148

Domain	Start	End	E-Value	Type
CA	45	131	6.34e-2	SMART
CA	155	240	2.98e-18	SMART
CA	264	348	2.17e-29	SMART
CA	372	453	2.84e-24	SMART
CA	477	563	5.02e-25	SMART
CA	594	675	8.16e-16	SMART
transmembrane domain	695	717	N/A	INTRINSIC

Coding Region Coverage

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined. [provided by RefSeq, Jul 2008]

Allele List at MGI

Other mutations in this stock

Total: 52 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
A2ml1	C	T	6: 128,530,301 (GRCm39)		probably benign	Het
Ap1b1	T	C	11: 4,989,169 (GRCm39)	L782P	probably damaging	Het
Arid1a	T	C	4: 133,408,765 (GRCm39)	D1914G	unknown	Het
C8a	G	A	4: 104,719,808 (GRCm39)	Q57*	probably null	Het
Cachd1	T	C	4: 100,850,069 (GRCm39)	S1144P	probably damaging	Het
Cdh23	A	T	10: 60,255,598 (GRCm39)		probably null	Het
Cenpe	A	G	3: 134,924,268 (GRCm39)	Q198R	possibly damaging	Het
Cpne8	T	C	15: 90,453,700 (GRCm39)	I228V	probably benign	Het
Cr2	A	T	1: 194,833,222 (GRCm39)		probably benign	Het
Csmd3	T	C	15: 47,522,395 (GRCm39)		probably benign	Het
Cyp2c23	A	G	19: 43,994,046 (GRCm39)	V440A	probably benign	Het
Dag1	T	C	9: 108,085,281 (GRCm39)	D620G	possibly damaging	Het
Dmxl1	T	A	18: 50,011,449 (GRCm39)	L1202*	probably null	Het
Dnah3	T	G	7: 119,542,798 (GRCm39)	H3538P	probably benign	Het
Dock8	A	T	19: 25,067,292 (GRCm39)	Q312L	probably benign	Het
E2f7	T	G	10: 110,610,596 (GRCm39)	V407G	probably benign	Het
F13b	T	C	1: 139,444,165 (GRCm39)	S500P	probably damaging	Het
F5	A	G	1: 164,039,395 (GRCm39)	I2002V	probably benign	Het
Flywch1	T	A	17: 23,979,319 (GRCm39)	M439L	possibly damaging	Het
Gcn1	C	A	5: 115,757,759 (GRCm39)	A2488E	probably damaging	Het
Gria1	T	C	11: 57,208,600 (GRCm39)	S832P	probably damaging	Het
Hnrnpr	T	C	4: 136,066,724 (GRCm39)		probably benign	Het
Hps3	A	G	3: 20,083,165 (GRCm39)	I177T	probably benign	Het
Irgm2	G	A	11: 58,111,167 (GRCm39)	G298D	probably benign	Het
Kcnk7	G	A	19: 5,756,230 (GRCm39)	G152D	probably damaging	Het
Man2a2	T	C	7: 80,012,654 (GRCm39)	T620A	probably benign	Het
Mapk12	A	G	15: 89,021,669 (GRCm39)		probably benign	Het
Mapk6	T	C	9: 75,297,572 (GRCm39)	Y315C	probably damaging	Het
Mdga2	T	A	12: 66,769,905 (GRCm39)		probably null	Het
Met	T	A	6: 17,491,700 (GRCm39)	I154N	probably damaging	Het
Mtrex	T	C	13: 113,055,095 (GRCm39)		probably benign	Het
Nap1l1	A	G	10: 111,328,772 (GRCm39)	R234G	possibly damaging	Het
Olfm5	C	A	7: 103,809,951 (GRCm39)	V137F	possibly damaging	Het
Or4d11	G	T	19: 12,014,041 (GRCm39)	H22N	probably benign	Het
Pfkm	T	C	15: 98,027,187 (GRCm39)	V620A	possibly damaging	Het
Rbak	A	G	5: 143,162,355 (GRCm39)		probably benign	Het
Rbl2	A	G	8: 91,816,844 (GRCm39)	I401M	probably benign	Het
Rragc	T	C	4: 123,814,852 (GRCm39)	S183P	probably damaging	Het
Septin3	A	G	15: 82,163,814 (GRCm39)		probably benign	Het
Slc22a6	A	T	19: 8,603,578 (GRCm39)		probably benign	Het
Spag4	A	T	2: 155,910,417 (GRCm39)	T348S	probably benign	Het
Sptbn1	T	C	11: 30,054,623 (GRCm39)	R2157G	probably benign	Het
Tmem168	G	A	6: 13,582,940 (GRCm39)	T263M	probably damaging	Het
Tnik	T	A	3: 28,625,007 (GRCm39)		probably null	Het
Tnpo2	T	A	8: 85,777,137 (GRCm39)	V549E	probably damaging	Het
Ttll7	A	C	3: 146,645,776 (GRCm39)	K545Q	possibly damaging	Het
Tubgcp5	T	G	7: 55,449,221 (GRCm39)	D139E	probably benign	Het
Vmn1r233	T	A	17: 21,214,861 (GRCm39)	N30Y	probably damaging	Het
Vmn2r25	T	G	6: 123,829,962 (GRCm39)	D63A	possibly damaging	Het
Vmn2r79	T	A	7: 86,686,485 (GRCm39)	L622Q	probably damaging	Het
Vmn2r84	T	C	10: 130,222,148 (GRCm39)	M691V	probably benign	Het
Zc3hc1	A	T	6: 30,372,729 (GRCm39)		probably benign	Het

Other mutations in Pcdha11

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01522:Pcdha11	APN	18	37,318,061 (GRCm39)	missense	probably damaging	1.00
R1165:Pcdha11	UTSW	18	37,140,757 (GRCm39)	intron	probably benign
R2422:Pcdha11	UTSW	18	37,140,325 (GRCm39)	missense	probably damaging	0.99
R2423:Pcdha11	UTSW	18	37,140,477 (GRCm39)	missense	possibly damaging	0.89
R2508:Pcdha11	UTSW	18	37,145,907 (GRCm39)	missense	possibly damaging	0.86
R3114:Pcdha11	UTSW	18	37,144,860 (GRCm39)	missense	probably damaging	1.00
R4173:Pcdha11	UTSW	18	37,145,676 (GRCm39)	missense	probably damaging	0.99
R4255:Pcdha11	UTSW	18	37,145,843 (GRCm39)	missense	probably benign	0.23
R4369:Pcdha11	UTSW	18	37,139,796 (GRCm39)	missense	possibly damaging	0.70
R4454:Pcdha11	UTSW	18	37,140,426 (GRCm39)	missense	probably benign	0.13
R4489:Pcdha11	UTSW	18	37,139,969 (GRCm39)	missense	possibly damaging	0.78
R4626:Pcdha11	UTSW	18	37,140,051 (GRCm39)	missense	probably damaging	1.00
R4751:Pcdha11	UTSW	18	37,139,997 (GRCm39)	missense	probably damaging	1.00
R4801:Pcdha11	UTSW	18	37,138,518 (GRCm39)	missense	probably damaging	1.00
R4802:Pcdha11	UTSW	18	37,138,518 (GRCm39)	missense	probably damaging	1.00
R4857:Pcdha11	UTSW	18	37,144,505 (GRCm39)	missense	probably benign	0.02
R4995:Pcdha11	UTSW	18	37,144,080 (GRCm39)	missense	probably benign	0.24
R5042:Pcdha11	UTSW	18	37,144,649 (GRCm39)	missense	probably damaging	1.00
R5480:Pcdha11	UTSW	18	37,138,935 (GRCm39)	missense	probably benign	0.04
R5495:Pcdha11	UTSW	18	37,144,079 (GRCm39)	missense	probably benign
R5523:Pcdha11	UTSW	18	37,145,439 (GRCm39)	missense	probably damaging	1.00
R5584:Pcdha11	UTSW	18	37,139,818 (GRCm39)	missense	probably damaging	1.00
R5682:Pcdha11	UTSW	18	37,144,502 (GRCm39)	missense	probably damaging	1.00
R5834:Pcdha11	UTSW	18	37,145,676 (GRCm39)	missense	probably damaging	0.99
R5842:Pcdha11	UTSW	18	37,144,337 (GRCm39)	missense	possibly damaging	0.85
R5859:Pcdha11	UTSW	18	37,140,336 (GRCm39)	missense	probably damaging	1.00
R6110:Pcdha11	UTSW	18	37,144,509 (GRCm39)	missense	probably damaging	1.00
R6135:Pcdha11	UTSW	18	37,138,870 (GRCm39)	missense	probably damaging	1.00
R6248:Pcdha11	UTSW	18	37,138,950 (GRCm39)	missense	probably benign	0.26
R6416:Pcdha11	UTSW	18	37,145,222 (GRCm39)	splice site	probably null
R6450:Pcdha11	UTSW	18	37,146,215 (GRCm39)	missense	probably damaging	1.00
R6594:Pcdha11	UTSW	18	37,144,235 (GRCm39)	missense	probably benign	0.04
R6631:Pcdha11	UTSW	18	37,138,844 (GRCm39)	missense	probably damaging	1.00
R6883:Pcdha11	UTSW	18	37,144,242 (GRCm39)	missense	probably damaging	1.00
R7088:Pcdha11	UTSW	18	37,138,470 (GRCm39)	missense	probably benign	0.00
R7129:Pcdha11	UTSW	18	37,140,291 (GRCm39)	missense	probably benign	0.45
R7153:Pcdha11	UTSW	18	37,144,278 (GRCm39)	missense	probably damaging	1.00
R7244:Pcdha11	UTSW	18	37,144,421 (GRCm39)	nonsense	probably null
R7295:Pcdha11	UTSW	18	37,139,979 (GRCm39)	missense	probably damaging	1.00
R7319:Pcdha11	UTSW	18	37,146,245 (GRCm39)	missense	probably benign	0.10
R7352:Pcdha11	UTSW	18	37,139,898 (GRCm39)	missense	probably damaging	1.00
R7516:Pcdha11	UTSW	18	37,144,671 (GRCm39)	missense	probably damaging	1.00
R7519:Pcdha11	UTSW	18	37,139,319 (GRCm39)	nonsense	probably null
R7660:Pcdha11	UTSW	18	37,138,904 (GRCm39)	missense	probably benign	0.17
R7677:Pcdha11	UTSW	18	37,144,605 (GRCm39)	missense	probably damaging	1.00
R7707:Pcdha11	UTSW	18	37,144,845 (GRCm39)	missense	probably benign	0.00
R7775:Pcdha11	UTSW	18	37,145,733 (GRCm39)	missense	possibly damaging	0.64
R7778:Pcdha11	UTSW	18	37,145,733 (GRCm39)	missense	possibly damaging	0.64
R7780:Pcdha11	UTSW	18	37,145,849 (GRCm39)	missense	probably damaging	0.97
R7916:Pcdha11	UTSW	18	37,140,441 (GRCm39)	missense	probably benign	0.01
R7991:Pcdha11	UTSW	18	37,145,909 (GRCm39)	missense	probably damaging	0.99
R8068:Pcdha11	UTSW	18	37,138,618 (GRCm39)	missense	probably damaging	1.00
R8220:Pcdha11	UTSW	18	37,139,624 (GRCm39)	missense	probably benign	0.01
R8252:Pcdha11	UTSW	18	37,140,590 (GRCm39)	missense	possibly damaging	0.65
R8392:Pcdha11	UTSW	18	37,139,212 (GRCm39)	nonsense	probably null
R8398:Pcdha11	UTSW	18	37,146,116 (GRCm39)	missense	possibly damaging	0.65
R8470:Pcdha11	UTSW	18	37,145,937 (GRCm39)	missense	probably benign	0.07
R8812:Pcdha11	UTSW	18	37,140,716 (GRCm39)	missense	probably benign	0.00
R8900:Pcdha11	UTSW	18	37,145,799 (GRCm39)	missense	probably damaging	1.00
R8968:Pcdha11	UTSW	18	37,145,307 (GRCm39)	missense	probably damaging	1.00
R9065:Pcdha11	UTSW	18	37,139,877 (GRCm39)	missense	possibly damaging	0.93
R9192:Pcdha11	UTSW	18	37,140,527 (GRCm39)	missense	probably benign	0.42
R9224:Pcdha11	UTSW	18	37,139,073 (GRCm39)	missense	probably damaging	0.99
R9228:Pcdha11	UTSW	18	37,144,512 (GRCm39)	missense	probably damaging	1.00
R9237:Pcdha11	UTSW	18	37,145,260 (GRCm39)	missense	probably damaging	1.00
R9336:Pcdha11	UTSW	18	37,144,514 (GRCm39)	missense	probably damaging	1.00
R9449:Pcdha11	UTSW	18	37,145,484 (GRCm39)	missense	probably damaging	1.00
R9475:Pcdha11	UTSW	18	37,140,591 (GRCm39)	missense	probably damaging	1.00
R9476:Pcdha11	UTSW	18	37,139,532 (GRCm39)	missense	probably benign	0.26
R9510:Pcdha11	UTSW	18	37,139,532 (GRCm39)	missense	probably benign	0.26
R9578:Pcdha11	UTSW	18	37,140,176 (GRCm39)	missense	probably damaging	1.00
R9654:Pcdha11	UTSW	18	37,145,333 (GRCm39)	missense	probably damaging	1.00
RF017:Pcdha11	UTSW	18	37,138,577 (GRCm39)	missense	possibly damaging	0.92
Z1177:Pcdha11	UTSW	18	37,145,976 (GRCm39)	missense	probably benign	0.43

Posted On

2014-05-07