Incidental Mutation 'IGL01862:Zfp202'
ID178359
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Zfp202
Ensembl Gene ENSMUSG00000025602
Gene Namezinc finger protein 202
SynonymsC130037E22Rik
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.074) question?
Stock #IGL01862
Quality Score
Status
Chromosome9
Chromosomal Location40192316-40213604 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to G at 40211828 bp
ZygosityHeterozygous
Amino Acid Change Isoleucine to Valine at position 629 (I629V)
Ref Sequence ENSEMBL: ENSMUSP00000026693 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000026693] [ENSMUST00000168691] [ENSMUST00000168832]
Predicted Effect probably benign
Transcript: ENSMUST00000026693
AA Change: I629V

PolyPhen 2 Score 0.392 (Sensitivity: 0.90; Specificity: 0.89)
SMART Domains Protein: ENSMUSP00000026693
Gene: ENSMUSG00000025602
AA Change: I629V

DomainStartEndE-ValueType
SCAN 42 154 1.19e-75 SMART
KRAB 237 297 1.7e-17 SMART
ZnF_C2H2 391 413 9.44e-2 SMART
ZnF_C2H2 419 441 6.42e-4 SMART
ZnF_C2H2 473 495 3.44e-4 SMART
ZnF_C2H2 501 523 1.47e-3 SMART
ZnF_C2H2 529 551 1.64e-1 SMART
ZnF_C2H2 557 579 3.11e-2 SMART
ZnF_C2H2 585 607 8.47e-4 SMART
ZnF_C2H2 613 635 3.39e-3 SMART
Predicted Effect probably benign
Transcript: ENSMUST00000168691
SMART Domains Protein: ENSMUSP00000130163
Gene: ENSMUSG00000025602

DomainStartEndE-ValueType
SCAN 42 132 1.03e-56 SMART
Predicted Effect probably benign
Transcript: ENSMUST00000168832
SMART Domains Protein: ENSMUSP00000132131
Gene: ENSMUSG00000025602

DomainStartEndE-ValueType
SCAN 42 154 1.19e-75 SMART
KRAB 237 277 5.32e-2 SMART
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 60 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
4933406M09Rik G A 1: 134,390,611 V374I probably benign Het
Abca8b G T 11: 109,947,171 S1085* probably null Het
Akap9 T G 5: 3,951,705 S94A probably damaging Het
Akap9 T A 5: 4,065,856 N3425K probably damaging Het
Anapc7 T A 5: 122,440,119 I389N probably benign Het
Aqp7 G A 4: 41,045,321 R20* probably null Het
Cacna1h C T 17: 25,383,483 G1524R probably damaging Het
Cacng4 T C 11: 107,794,370 Y32C probably damaging Het
Ccdc130 G T 8: 84,260,534 probably benign Het
Cep120 A C 18: 53,714,767 S673R probably benign Het
Cep162 T C 9: 87,253,933 E19G possibly damaging Het
Cpxm2 C T 7: 132,059,811 V416I probably benign Het
Dapk1 A G 13: 60,726,610 T427A probably benign Het
Ecm1 A T 3: 95,734,273 D549E probably benign Het
Efemp1 T A 11: 28,921,428 N342K probably damaging Het
Erc2 T C 14: 28,271,569 probably benign Het
Fam160b2 C T 14: 70,587,690 R402H probably benign Het
Galnt13 T C 2: 54,857,914 V269A probably damaging Het
Gm6465 T G 5: 11,849,053 L171R probably damaging Het
Gpatch1 A G 7: 35,295,278 V521A probably benign Het
Heatr5b A T 17: 78,796,485 V1087E possibly damaging Het
Ikzf2 A T 1: 69,538,898 V484D probably damaging Het
Ints4 T A 7: 97,541,153 V953E probably damaging Het
Iqce T C 5: 140,699,725 D15G possibly damaging Het
Kif3a T A 11: 53,570,541 N4K possibly damaging Het
Lrch4 A T 5: 137,637,009 I254F probably damaging Het
Ly75 A T 2: 60,299,172 V1623D probably damaging Het
Mapt T A 11: 104,290,002 probably benign Het
Mast1 A T 8: 84,913,246 probably null Het
Mcc G T 18: 44,759,296 Q84K probably benign Het
Mtfr2 G A 10: 20,348,403 V28M probably benign Het
Myh8 T A 11: 67,289,694 Y585* probably null Het
Napsa T C 7: 44,582,493 V202A probably damaging Het
Nsd2 A G 5: 33,843,736 K199R probably null Het
Ntpcr C T 8: 125,736,098 A18V probably benign Het
Olfr1009 G T 2: 85,722,128 C241F probably damaging Het
Olfr117 G T 17: 37,659,477 N285K probably damaging Het
Olfr169 A T 16: 19,566,676 M69K probably damaging Het
Olfr689 T A 7: 105,314,232 I76N probably damaging Het
Olfr877 A G 9: 37,855,181 D121G probably damaging Het
Os9 A G 10: 127,099,704 V299A probably benign Het
Pcdhb7 T C 18: 37,343,862 S684P possibly damaging Het
Phf19 A C 2: 34,897,055 probably null Het
Pkd1l3 G A 8: 109,631,276 probably null Het
Pkhd1 A G 1: 20,358,910 I2422T probably damaging Het
Plxna2 T A 1: 194,643,950 V64E possibly damaging Het
Psme4 T A 11: 30,812,038 C459* probably null Het
Ptk6 T C 2: 181,199,640 S159G probably benign Het
Rhd T C 4: 134,890,339 I329T possibly damaging Het
Scfd1 A G 12: 51,445,711 Y601C probably damaging Het
Shroom3 T C 5: 92,962,289 S1753P probably damaging Het
Slc8a1 A C 17: 81,442,201 probably null Het
Spg7 T A 8: 123,076,930 L233Q probably damaging Het
Strip1 C A 3: 107,621,882 R353L probably damaging Het
Ubr1 T C 2: 120,934,342 N544D possibly damaging Het
Ubr4 A G 4: 139,477,158 T4794A possibly damaging Het
Usp24 A G 4: 106,408,898 probably benign Het
Vmn1r193 A T 13: 22,219,814 C3S probably benign Het
Zdhhc5 C T 2: 84,690,492 R447H probably benign Het
Zfp462 T A 4: 55,023,441 C990S probably damaging Het
Other mutations in Zfp202
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00662:Zfp202 APN 9 40211043 missense probably benign 0.02
IGL03069:Zfp202 APN 9 40211399 missense probably damaging 1.00
R0028:Zfp202 UTSW 9 40211752 missense probably damaging 1.00
R0158:Zfp202 UTSW 9 40208916 nonsense probably null
R0278:Zfp202 UTSW 9 40208482 missense probably benign 0.15
R1132:Zfp202 UTSW 9 40211022 missense probably benign 0.00
R1404:Zfp202 UTSW 9 40211496 missense probably damaging 1.00
R1404:Zfp202 UTSW 9 40211496 missense probably damaging 1.00
R1764:Zfp202 UTSW 9 40210466 missense probably benign 0.00
R1928:Zfp202 UTSW 9 40209787 missense probably damaging 1.00
R2929:Zfp202 UTSW 9 40211688 missense possibly damaging 0.94
R3153:Zfp202 UTSW 9 40208438 missense probably benign 0.00
R3948:Zfp202 UTSW 9 40208425 missense probably benign 0.43
R4190:Zfp202 UTSW 9 40211337 missense probably benign 0.00
R4273:Zfp202 UTSW 9 40207494 nonsense probably null
R6181:Zfp202 UTSW 9 40207342 missense probably damaging 1.00
R6182:Zfp202 UTSW 9 40207342 missense probably damaging 1.00
R6816:Zfp202 UTSW 9 40211813 missense probably damaging 1.00
R6835:Zfp202 UTSW 9 40210235 intron probably null
X0012:Zfp202 UTSW 9 40211184 missense probably damaging 1.00
Posted On2014-05-07